JP2010273685A5 - - Google Patents

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Publication number
JP2010273685A5
JP2010273685A5 JP2010166570A JP2010166570A JP2010273685A5 JP 2010273685 A5 JP2010273685 A5 JP 2010273685A5 JP 2010166570 A JP2010166570 A JP 2010166570A JP 2010166570 A JP2010166570 A JP 2010166570A JP 2010273685 A5 JP2010273685 A5 JP 2010273685A5
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JP
Japan
Prior art keywords
protein
antibody
seq
vertebrate
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010166570A
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English (en)
Japanese (ja)
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JP2010273685A (ja
Filing date
Publication date
Priority claimed from US08/400,159 external-priority patent/US5869282A/en
Application filed filed Critical
Publication of JP2010273685A publication Critical patent/JP2010273685A/ja
Publication of JP2010273685A5 publication Critical patent/JP2010273685A5/ja
Withdrawn legal-status Critical Current

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JP2010166570A 1995-03-07 2010-07-23 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法 Withdrawn JP2010273685A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/400,159 US5869282A (en) 1991-12-11 1995-03-07 Nucleotide and protein sequences of the serrate gene and methods based thereon

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007260391A Division JP2008099687A (ja) 1995-03-07 2007-10-03 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013023179A Division JP2013150605A (ja) 1995-03-07 2013-02-08 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Publications (2)

Publication Number Publication Date
JP2010273685A JP2010273685A (ja) 2010-12-09
JP2010273685A5 true JP2010273685A5 (https=) 2011-07-14

Family

ID=23582455

Family Applications (4)

Application Number Title Priority Date Filing Date
JP8527061A Withdrawn JPH11507203A (ja) 1995-03-07 1996-03-07 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2007260391A Withdrawn JP2008099687A (ja) 1995-03-07 2007-10-03 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2010166570A Withdrawn JP2010273685A (ja) 1995-03-07 2010-07-23 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2013023179A Withdrawn JP2013150605A (ja) 1995-03-07 2013-02-08 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP8527061A Withdrawn JPH11507203A (ja) 1995-03-07 1996-03-07 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2007260391A Withdrawn JP2008099687A (ja) 1995-03-07 2007-10-03 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013023179A Withdrawn JP2013150605A (ja) 1995-03-07 2013-02-08 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Country Status (11)

Country Link
US (1) US5869282A (https=)
EP (1) EP0813545B1 (https=)
JP (4) JPH11507203A (https=)
AT (1) ATE442381T1 (https=)
AU (1) AU718955B2 (https=)
CA (1) CA2214830C (https=)
DE (1) DE69638022D1 (https=)
DK (1) DK0813545T3 (https=)
ES (1) ES2333384T3 (https=)
PT (1) PT813545E (https=)
WO (1) WO1996027610A1 (https=)

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US6887475B1 (en) 1996-11-07 2005-05-03 Lorantis Limited Notch
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US6136952A (en) 1997-06-25 2000-10-24 University Of Washington Human jagged polypeptide, encoding nucleic acids and methods of use
US6692919B1 (en) 1997-07-23 2004-02-17 Yale University Activated forms of notch and methods based thereon
US6436650B1 (en) 1997-07-23 2002-08-20 Yale University Activated forms of notch and methods based thereon
AU1054900A (en) * 1998-10-30 2000-05-22 Smith & Nephew Plc Compositions comprising notch receptor manipulating agents
US8084258B2 (en) * 1999-07-12 2011-12-27 University Of Basel Manipulation of tissue of organ type using the notch pathway
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US8044259B2 (en) 2000-08-03 2011-10-25 The Regents Of The University Of Michigan Determining the capability of a test compound to affect solid tumor stem cells
US6984522B2 (en) * 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
AU2001288628A1 (en) * 2000-08-31 2002-03-13 Loyola University Chicago Method and reagents for treatment of skin disorders by modulating the notch pathway
ATE398175T1 (de) * 2000-12-08 2008-07-15 Coley Pharmaceuticals Gmbh Cpg-artige nukleinsäuren und verfahren zu ihrer verwendung
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WO2003011317A1 (en) * 2001-07-25 2003-02-13 Lorantis Limited Modulators of notch signalling for use in immunotherapy
CA2469204A1 (en) * 2001-12-07 2003-06-19 Regents Of The University Of Michigan Prospective identification and characterization of breast cancer stem cells
US20030185829A1 (en) * 2002-03-12 2003-10-02 Erich Koller Jagged 2 inhibitors for inducing apoptosis
US20040102401A1 (en) * 2002-11-22 2004-05-27 Isis Pharmaceuticals Inc. Modulation of jagged 1 expression
GB0300428D0 (en) * 2003-01-09 2003-02-05 Lorantis Ltd Medical treatment
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EP1639090A4 (en) * 2003-06-09 2008-04-16 Univ Michigan COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
AU2005209909B8 (en) * 2004-02-03 2009-01-15 The Regents Of The University Of Michigan Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
US20060252073A1 (en) * 2005-04-18 2006-11-09 Regents Of The University Of Michigan Compositions and methods for the treatment of cancer
WO2006135886A2 (en) * 2005-06-13 2006-12-21 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
EP1907858A4 (en) * 2005-06-13 2009-04-08 Univ Michigan COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
JP5129149B2 (ja) 2005-10-31 2013-01-23 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 癌を処置および診断するための組成物および方法
DK2500360T3 (en) 2005-10-31 2015-10-26 Oncomed Pharm Inc Compositions and methods for the diagnosis and treatment of cancer
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
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TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Wnt拮抗劑及治療和篩選方法
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US20130095079A1 (en) 2010-04-09 2013-04-18 Fred Hutchinson Cancer Research Center Compositions and methods for providing hematopoietic function without hla matching
US20130095080A1 (en) 2010-04-09 2013-04-18 Fred Hutchinson Cancer Reserach Center Compositions and methods for providing hematopoietic function
CA2858069C (en) 2011-12-08 2020-02-11 Novartis Ag Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells
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JP2016510411A (ja) 2013-02-04 2016-04-07 オンコメッド ファーマシューティカルズ インコーポレイテッド Wnt経路インヒビターによる処置の方法およびモニタリング
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MX389160B (es) 2013-10-31 2025-03-20 Hutchinson Fred Cancer Res Células no t efectoras y madre/progenitoras hematopoyéticas modificadas y usos de estas.
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CN113195707A (zh) * 2018-08-17 2021-07-30 频率治疗公司 用于通过上调jag-1来生成毛细胞的组合物和方法
CN112680471B (zh) * 2019-10-17 2023-08-01 华南农业大学 ZmSPL基因在调控玉米柱头乳突细胞发育中的应用
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WO1993012141A1 (en) * 1991-12-11 1993-06-24 Yale University Nucleotide and protein sequences of the serrate gene and methods based thereon
US5786158A (en) * 1992-04-30 1998-07-28 Yale University Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
DE69635899T2 (de) * 1995-11-17 2006-11-23 Asahi Kasei Kabushiki Kaisha Polypeptid, das die differenzierung unterdrueckt
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