JP2012518988A5 - - Google Patents
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- JP2012518988A5 JP2012518988A5 JP2011536662A JP2011536662A JP2012518988A5 JP 2012518988 A5 JP2012518988 A5 JP 2012518988A5 JP 2011536662 A JP2011536662 A JP 2011536662A JP 2011536662 A JP2011536662 A JP 2011536662A JP 2012518988 A5 JP2012518988 A5 JP 2012518988A5
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- 210000004027 cell Anatomy 0.000 claims 17
- 210000001082 somatic cell Anatomy 0.000 claims 15
- 239000000126 substance Substances 0.000 claims 15
- 108020004707 nucleic acids Proteins 0.000 claims 11
- 102000039446 nucleic acids Human genes 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 102100033575 Doublesex- and mab-3-related transcription factor B1 Human genes 0.000 claims 9
- 101000871973 Homo sapiens Doublesex- and mab-3-related transcription factor B1 Proteins 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 241000131390 Glis Species 0.000 claims 6
- 239000000463 material Substances 0.000 claims 6
- 108700021430 Kruppel-Like Factor 4 Proteins 0.000 claims 5
- 101150086694 SLC22A3 gene Proteins 0.000 claims 5
- 230000001939 inductive effect Effects 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 5
- 101000857270 Homo sapiens Zinc finger protein GLIS1 Proteins 0.000 claims 4
- 102100023527 Iroquois-class homeodomain protein IRX-6 Human genes 0.000 claims 4
- 101710136138 Iroquois-class homeodomain protein IRX-6 Proteins 0.000 claims 4
- 102100036090 Pituitary homeobox 2 Human genes 0.000 claims 4
- 102100025883 Zinc finger protein GLIS1 Human genes 0.000 claims 4
- 101000595669 Homo sapiens Pituitary homeobox 2 Proteins 0.000 claims 3
- 102100038895 Myc proto-oncogene protein Human genes 0.000 claims 3
- 101710135898 Myc proto-oncogene protein Proteins 0.000 claims 3
- 101100247004 Rattus norvegicus Qsox1 gene Proteins 0.000 claims 3
- 101710150448 Transcriptional regulator Myc Proteins 0.000 claims 3
- 108091057508 Myc family Proteins 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000000411 inducer Substances 0.000 claims 2
- 101100257372 Caenorhabditis elegans sox-3 gene Proteins 0.000 claims 1
- 101100310657 Mus musculus Sox1 gene Proteins 0.000 claims 1
- 101100310648 Mus musculus Sox17 gene Proteins 0.000 claims 1
- 101100310650 Mus musculus Sox18 gene Proteins 0.000 claims 1
- 101100257376 Mus musculus Sox3 gene Proteins 0.000 claims 1
- 101100043062 Mus musculus Sox7 gene Proteins 0.000 claims 1
- 108700026495 N-Myc Proto-Oncogene Proteins 0.000 claims 1
- 102100030124 N-myc proto-oncogene protein Human genes 0.000 claims 1
- 101710106040 Pituitary homeobox 2 Proteins 0.000 claims 1
- 102000001708 Protein Isoforms Human genes 0.000 claims 1
- 108010029485 Protein Isoforms Proteins 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 238000011419 induction treatment Methods 0.000 claims 1
- 230000000392 somatic effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20885309P | 2009-02-27 | 2009-02-27 | |
| US61/208,853 | 2009-02-27 | ||
| US27612309P | 2009-09-08 | 2009-09-08 | |
| US61/276,123 | 2009-09-08 | ||
| PCT/JP2010/053024 WO2010098419A1 (en) | 2009-02-27 | 2010-02-19 | Novel nuclear reprogramming substance |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012518988A JP2012518988A (ja) | 2012-08-23 |
| JP2012518988A5 true JP2012518988A5 (enExample) | 2013-02-21 |
| JP5553289B2 JP5553289B2 (ja) | 2014-07-16 |
Family
ID=42665623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536662A Active JP5553289B2 (ja) | 2009-02-27 | 2010-02-19 | 新規核初期化物質 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8951801B2 (enExample) |
| EP (2) | EP2607476B1 (enExample) |
| JP (1) | JP5553289B2 (enExample) |
| KR (1) | KR101764100B1 (enExample) |
| CN (1) | CN102388136B (enExample) |
| CA (1) | CA2753845C (enExample) |
| IL (1) | IL214833A (enExample) |
| SG (1) | SG173876A1 (enExample) |
| WO (1) | WO2010098419A1 (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101764100B1 (ko) | 2009-02-27 | 2017-08-02 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 신규한 핵 재프로그래밍 물질 |
| JP5765746B2 (ja) | 2010-02-16 | 2015-08-19 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| EP2647699B1 (en) | 2010-12-03 | 2020-04-01 | Kyoto University | Efficient method for establishing induced pluripotent stem cells |
| US9404082B2 (en) | 2010-12-03 | 2016-08-02 | Kyoto University | Method for production of eosinophil from pluripotent stem cell |
| US9758765B2 (en) | 2011-04-08 | 2017-09-12 | Osaka University | Modified laminin and use thereof |
| WO2012141181A1 (ja) * | 2011-04-11 | 2012-10-18 | 国立大学法人京都大学 | 核初期化物質 |
| KR101334404B1 (ko) * | 2011-04-28 | 2013-12-12 | 포항공과대학교 산학협력단 | 배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법 |
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| JP6162604B2 (ja) | 2011-10-21 | 2017-07-12 | 国立大学法人京都大学 | 層流による多能性維持単一分散細胞培養法 |
| WO2013077423A1 (ja) | 2011-11-25 | 2013-05-30 | 国立大学法人京都大学 | 多能性幹細胞の培養方法 |
| HUE041853T2 (hu) | 2012-05-21 | 2019-05-28 | Univ California | Humán IPS sejtek elõállítása szintetikus önreplikációra képes RNS segítségével |
| JP6495658B2 (ja) | 2013-02-08 | 2019-04-03 | 国立大学法人京都大学 | 巨核球及び血小板の製造方法 |
| WO2014136581A1 (ja) | 2013-03-06 | 2014-09-12 | 国立大学法人京都大学 | 多能性幹細胞の培養システム及び多能性幹細胞の継代方法 |
| EP2977449B1 (en) | 2013-03-21 | 2020-02-26 | Kyoto University | Pluripotent stem cell for neuronal differentiation induction |
| WO2014157257A1 (ja) | 2013-03-25 | 2014-10-02 | 公益財団法人先端医療振興財団 | 細胞の選別方法 |
| JP6461787B2 (ja) | 2013-04-12 | 2019-01-30 | 国立大学法人京都大学 | 肺胞上皮前駆細胞の誘導方法 |
| JP6429280B2 (ja) | 2013-05-14 | 2018-11-28 | 国立大学法人京都大学 | 効率的な心筋細胞の誘導方法 |
| CN105247041B (zh) | 2013-05-31 | 2018-04-20 | 爱心细胞有限公司 | 组入有水凝胶的层叠细胞膜片 |
| EP3020803B1 (en) | 2013-06-11 | 2020-03-11 | Kyoto University | Method for producing renal precursor cells |
| JP6516672B2 (ja) | 2013-07-26 | 2019-05-22 | 京都府公立大学法人 | 骨芽細胞及びその調製方法 |
| US9796962B2 (en) | 2013-08-07 | 2017-10-24 | Kyoto University | Method for generating pancreatic hormone-producing cells |
| SG11201601720RA (en) | 2013-09-05 | 2016-04-28 | Univ Kyoto | New method for inducing dopamine-producing neural precursor cells |
| JP6635505B2 (ja) | 2013-11-01 | 2020-01-29 | 国立大学法人京都大学 | 新規軟骨細胞誘導方法 |
| EP3929302A1 (en) | 2014-07-14 | 2021-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method for identifying epitope on protein |
| US12241089B2 (en) | 2014-07-18 | 2025-03-04 | Kyoto University | Method for inducing t cells for cell-based immunotherapy from pluripotent stem cells |
| WO2016104717A1 (ja) | 2014-12-26 | 2016-06-30 | 国立大学法人京都大学 | 肝細胞誘導方法 |
| EP3081638A1 (en) | 2015-04-16 | 2016-10-19 | Kyoto University | Method for producing pseudo-islets |
| WO2017059241A1 (en) | 2015-10-02 | 2017-04-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Lentiviral protein delivery system for rna-guided genome editing |
| PL3444334T3 (pl) | 2016-04-15 | 2022-01-10 | Kyoto University | Sposób indukowania limfocytów t cd8-dodatnich swoistych wobec antygenu |
| US11898163B2 (en) | 2016-04-22 | 2024-02-13 | Kyoto University | Method for producing dopaminergic neuron progenitor cell |
| WO2018124118A1 (ja) | 2016-12-27 | 2018-07-05 | 住友化学株式会社 | 人工多能性幹細胞の評価方法及び選抜方法、並びに人工多能性幹細胞の製造方法 |
| EP4053268B1 (en) | 2017-01-20 | 2025-10-08 | Kyoto University | Method for producing cd8alpha+beta+cytotoxic t cells |
| US20210130785A1 (en) | 2017-01-26 | 2021-05-06 | Osaka University | Medium for inducing differentiation of stem cells into mesodermal cells and method for producing mesodermal cells |
| JP7171055B2 (ja) | 2017-03-14 | 2022-11-15 | 国立大学法人京都大学 | 多能性幹細胞からヘルパーｔ細胞を製造する方法 |
| KR102761727B1 (ko) | 2017-05-25 | 2025-02-03 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 중간 중배엽 세포로부터 신장 전구 세포로의 분화 유도 방법 및 다능성 줄기세포로부터 신장 전구 세포로의 분화 유도 방법 |
| EP3643780A4 (en) | 2017-06-19 | 2021-04-07 | Foundation for Biomedical Research and Innovation at Kobe | METHOD FOR PREDICTING THE DIFFERENTIATION CAPACITY OF PLURIPOTENT STEM CELLS, AND ASSOCIATED REAGENT |
| EP3699267A4 (en) | 2017-10-17 | 2021-10-27 | Kyoto University | PROCESS FOR OBTAINING AN ARTIFICIAL NEUROMUSCULAR JUNCTION FROM PLURIPOTENT STEM CELLS |
| BR112021000437A2 (pt) | 2018-07-13 | 2021-04-06 | Kyoto University | Métodos para produzir uma célula t gama delta e para prevenir ou tratar tumor, célula t gama delta, população de célula, medicamento, agente de extermínio para uma célula, e, uso da célula |
| EP3824912A4 (en) | 2018-07-19 | 2022-04-20 | Kyoto University | PLATEFORM CARTILAGE DERIVED FROM PLURIPOTENTS STEM CELLS AND METHODS FOR PRODUCTION OF PLATEFORM CARTILAGE |
| US20210332329A1 (en) | 2018-07-23 | 2021-10-28 | Kyoto University | Novel renal progenitor cell marker and method for concentrating renal progenitor cells using same |
| US12168781B2 (en) | 2018-12-06 | 2024-12-17 | Kirin Holdings Kabushiki Kaisha | Production method for T cells or NK cells, medium for culturing T cells or NK cells, method for culturing T cells or NK cells, method for maintaining undifferentiated state of undifferentiated T cells, and growth-accelerating agent for T cells or NK cells |
| EP3900787A4 (en) | 2018-12-21 | 2022-02-23 | Kyoto University | LUBRICIN-LOCALIZED CARTILE-LIKE TISSUE, METHOD OF MANUFACTURE THEREOF AND COMPOSITION THEREOF FOR TREATMENT OF ARTICULATE-CARTILAGE DEFECTS |
| CN113226475A (zh) | 2018-12-26 | 2021-08-06 | 麒麟控股株式会社 | 改造tcr及其制造方法 |
| US20220145255A1 (en) | 2019-02-26 | 2022-05-12 | Tohoku University | Method for producing osteoblast cluster using ips cells |
| JP7700673B2 (ja) | 2019-05-15 | 2025-07-01 | 味の素株式会社 | 神経堤細胞または角膜上皮細胞の純化方法 |
| EP3974519A4 (en) | 2019-05-20 | 2023-07-12 | Ajinomoto Co., Inc. | EXPANSION CULTURE METHOD FOR CARTILAGE OR BONE PRECURSOR CELLS |
| EP4074321A4 (en) | 2019-12-12 | 2024-01-03 | National University Corporation Chiba University | Freeze-dried preparation containing megakaryocytes and platelets |
| AU2021225952A1 (en) | 2020-02-28 | 2022-10-20 | Takeda Pharmaceutical Company Limited | Method for producing natural killer cells from pluripotent stem cells |
| JPWO2021256522A1 (enExample) | 2020-06-17 | 2021-12-23 | ||
| EP4180516A4 (en) | 2020-07-13 | 2024-01-17 | Kyoto University | SKELETON MUSCLE PRECURSOR CELLS AND METHOD FOR PURIFICATION THEREOF, COMPOSITION FOR THE TREATMENT OF MYOGENIC DISEASES AND METHOD FOR PRODUCING SKELETON MUSCLE PRECURSOR CELLS CONTAINING CELL GROUPS |
| JPWO2022019152A1 (enExample) | 2020-07-20 | 2022-01-27 | ||
| US20240271088A1 (en) | 2020-08-18 | 2024-08-15 | Kyoto University | Method for maintaining and amplifying human primordial germ cells / human primordial germ cell-like cells |
| US20240182858A1 (en) | 2021-03-17 | 2024-06-06 | Astellas Pharma Inc. | Pericyte having basic fibroblast growth factor (bfgf) gene introduced therein |
| EP4314249A1 (en) | 2021-03-25 | 2024-02-07 | Bluerock Therapeutics LP | Methods for obtaining induced pluripotent stem cells |
| WO2022230977A1 (ja) | 2021-04-30 | 2022-11-03 | 国立研究開発法人理化学研究所 | 網膜色素上皮細胞のひも状凝集体、それを製造するためのデバイスおよび製造方法、ならびに該ひも状凝集体を含有する治療薬 |
| US20240254441A1 (en) | 2021-06-04 | 2024-08-01 | Kirin Holdings Kabushiki Kaisha | Cell composition, method for producing cell composition, and pharmaceutical composition containing cell composition |
| WO2022259721A1 (ja) | 2021-06-10 | 2022-12-15 | 味の素株式会社 | 間葉系幹細胞の製造方法 |
| CN117813374A (zh) | 2021-06-15 | 2024-04-02 | 武田药品工业株式会社 | 从多能干细胞产生自然杀伤细胞的方法 |
| JPWO2023286832A1 (enExample) | 2021-07-15 | 2023-01-19 | ||
| WO2023286834A1 (ja) | 2021-07-15 | 2023-01-19 | アステラス製薬株式会社 | 血管内皮増殖因子（ｖｅｇｆ）高発現ペリサイト様細胞 |
| JPWO2023017848A1 (enExample) | 2021-08-11 | 2023-02-16 | ||
| US20250041418A1 (en) | 2021-11-11 | 2025-02-06 | Healios K.K. | Gene-modified pluripotent stem cell, immunocompetent cell derived therefrom, method for producing said cells, and use thereof |
| JPWO2023153464A1 (enExample) | 2022-02-09 | 2023-08-17 | ||
| US20250290076A1 (en) | 2022-04-27 | 2025-09-18 | Kyoto University | Epicardial cell regeneration promoter and method for promoting epicardial cell regeneration |
| US20250376727A1 (en) | 2022-06-10 | 2025-12-11 | Kyoto University | Detection method and detection reagent for undifferentiated pluripotent stem cells |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| ATE367445T1 (de) | 1999-05-18 | 2007-08-15 | Dnavec Research Inc | Viraler paramyxoviridae vektor mit einem defekten hüllprotein-gen |
| KR101420740B1 (ko) * | 2005-12-13 | 2014-07-17 | 교또 다이가꾸 | 핵초기화 인자 |
| EP2137296A2 (en) * | 2007-03-23 | 2009-12-30 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| CN105861443A (zh) * | 2007-04-07 | 2016-08-17 | 怀特黑德生物医学研究所 | 体细胞重编程 |
| CN101802172A (zh) * | 2007-05-30 | 2010-08-11 | 通用医疗公司 | 由体细胞产生多能细胞的方法 |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| KR101564044B1 (ko) | 2007-10-31 | 2015-10-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 핵초기화 방법 |
| US20110231944A1 (en) | 2008-09-04 | 2011-09-22 | Riken | B cell-derived ips cells and application thereof |
| ES2549155T3 (es) | 2008-09-08 | 2015-10-23 | Riken | Células iPS obtenidas a partir de células NKT y células NKT obtenidas a partir de las mismas |
| KR101764100B1 (ko) | 2009-02-27 | 2017-08-02 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 신규한 핵 재프로그래밍 물질 |
| CN101613717B (zh) | 2009-04-17 | 2012-01-11 | 中国科学院广州生物医药与健康研究院 | 用猪成纤维细胞生成诱导的多能性干细胞的方法 |
| WO2011016588A1 (en) | 2009-08-07 | 2011-02-10 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| JP5765746B2 (ja) | 2010-02-16 | 2015-08-19 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
-
2010
- 2010-02-19 KR KR1020117022584A patent/KR101764100B1/ko active Active
- 2010-02-19 JP JP2011536662A patent/JP5553289B2/ja active Active
- 2010-02-19 EP EP13158495.5A patent/EP2607476B1/en active Active
- 2010-02-19 SG SG2011061959A patent/SG173876A1/en unknown
- 2010-02-19 EP EP10746298A patent/EP2401372A4/en not_active Withdrawn
- 2010-02-19 CN CN201080011401.7A patent/CN102388136B/zh active Active
- 2010-02-19 US US13/203,735 patent/US8951801B2/en active Active
- 2010-02-19 CA CA2753845A patent/CA2753845C/en active Active
- 2010-02-19 WO PCT/JP2010/053024 patent/WO2010098419A1/en not_active Ceased
-
2011
- 2011-08-25 IL IL214833A patent/IL214833A/en active IP Right Grant
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