KR101764100B1 - 신규한 핵 재프로그래밍 물질 - Google Patents
신규한 핵 재프로그래밍 물질 Download PDFInfo
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- KR101764100B1 KR101764100B1 KR1020117022584A KR20117022584A KR101764100B1 KR 101764100 B1 KR101764100 B1 KR 101764100B1 KR 1020117022584 A KR1020117022584 A KR 1020117022584A KR 20117022584 A KR20117022584 A KR 20117022584A KR 101764100 B1 KR101764100 B1 KR 101764100B1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20885309P | 2009-02-27 | 2009-02-27 | |
| US61/208,853 | 2009-02-27 | ||
| US27612309P | 2009-09-08 | 2009-09-08 | |
| US61/276,123 | 2009-09-08 | ||
| PCT/JP2010/053024 WO2010098419A1 (en) | 2009-02-27 | 2010-02-19 | Novel nuclear reprogramming substance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20120003867A KR20120003867A (ko) | 2012-01-11 |
| KR101764100B1 true KR101764100B1 (ko) | 2017-08-02 |
Family
ID=42665623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020117022584A Active KR101764100B1 (ko) | 2009-02-27 | 2010-02-19 | 신규한 핵 재프로그래밍 물질 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8951801B2 (enExample) |
| EP (2) | EP2607476B1 (enExample) |
| JP (1) | JP5553289B2 (enExample) |
| KR (1) | KR101764100B1 (enExample) |
| CN (1) | CN102388136B (enExample) |
| CA (1) | CA2753845C (enExample) |
| IL (1) | IL214833A (enExample) |
| SG (1) | SG173876A1 (enExample) |
| WO (1) | WO2010098419A1 (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101764100B1 (ko) | 2009-02-27 | 2017-08-02 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 신규한 핵 재프로그래밍 물질 |
| JP5765746B2 (ja) | 2010-02-16 | 2015-08-19 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| EP2647699B1 (en) | 2010-12-03 | 2020-04-01 | Kyoto University | Efficient method for establishing induced pluripotent stem cells |
| US9404082B2 (en) | 2010-12-03 | 2016-08-02 | Kyoto University | Method for production of eosinophil from pluripotent stem cell |
| US9758765B2 (en) | 2011-04-08 | 2017-09-12 | Osaka University | Modified laminin and use thereof |
| WO2012141181A1 (ja) * | 2011-04-11 | 2012-10-18 | 国立大学法人京都大学 | 核初期化物質 |
| KR101334404B1 (ko) * | 2011-04-28 | 2013-12-12 | 포항공과대학교 산학협력단 | 배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법 |
| CN107988381B (zh) | 2011-07-25 | 2021-05-28 | 国立大学法人京都大学 | 筛选诱导的多能干细胞的方法 |
| JP6162604B2 (ja) | 2011-10-21 | 2017-07-12 | 国立大学法人京都大学 | 層流による多能性維持単一分散細胞培養法 |
| WO2013077423A1 (ja) | 2011-11-25 | 2013-05-30 | 国立大学法人京都大学 | 多能性幹細胞の培養方法 |
| HUE041853T2 (hu) | 2012-05-21 | 2019-05-28 | Univ California | Humán IPS sejtek elõállítása szintetikus önreplikációra képes RNS segítségével |
| JP6495658B2 (ja) | 2013-02-08 | 2019-04-03 | 国立大学法人京都大学 | 巨核球及び血小板の製造方法 |
| WO2014136581A1 (ja) | 2013-03-06 | 2014-09-12 | 国立大学法人京都大学 | 多能性幹細胞の培養システム及び多能性幹細胞の継代方法 |
| EP2977449B1 (en) | 2013-03-21 | 2020-02-26 | Kyoto University | Pluripotent stem cell for neuronal differentiation induction |
| WO2014157257A1 (ja) | 2013-03-25 | 2014-10-02 | 公益財団法人先端医療振興財団 | 細胞の選別方法 |
| JP6461787B2 (ja) | 2013-04-12 | 2019-01-30 | 国立大学法人京都大学 | 肺胞上皮前駆細胞の誘導方法 |
| JP6429280B2 (ja) | 2013-05-14 | 2018-11-28 | 国立大学法人京都大学 | 効率的な心筋細胞の誘導方法 |
| CN105247041B (zh) | 2013-05-31 | 2018-04-20 | 爱心细胞有限公司 | 组入有水凝胶的层叠细胞膜片 |
| EP3020803B1 (en) | 2013-06-11 | 2020-03-11 | Kyoto University | Method for producing renal precursor cells |
| JP6516672B2 (ja) | 2013-07-26 | 2019-05-22 | 京都府公立大学法人 | 骨芽細胞及びその調製方法 |
| US9796962B2 (en) | 2013-08-07 | 2017-10-24 | Kyoto University | Method for generating pancreatic hormone-producing cells |
| SG11201601720RA (en) | 2013-09-05 | 2016-04-28 | Univ Kyoto | New method for inducing dopamine-producing neural precursor cells |
| JP6635505B2 (ja) | 2013-11-01 | 2020-01-29 | 国立大学法人京都大学 | 新規軟骨細胞誘導方法 |
| EP3929302A1 (en) | 2014-07-14 | 2021-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method for identifying epitope on protein |
| US12241089B2 (en) | 2014-07-18 | 2025-03-04 | Kyoto University | Method for inducing t cells for cell-based immunotherapy from pluripotent stem cells |
| WO2016104717A1 (ja) | 2014-12-26 | 2016-06-30 | 国立大学法人京都大学 | 肝細胞誘導方法 |
| EP3081638A1 (en) | 2015-04-16 | 2016-10-19 | Kyoto University | Method for producing pseudo-islets |
| WO2017059241A1 (en) | 2015-10-02 | 2017-04-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Lentiviral protein delivery system for rna-guided genome editing |
| PL3444334T3 (pl) | 2016-04-15 | 2022-01-10 | Kyoto University | Sposób indukowania limfocytów t cd8-dodatnich swoistych wobec antygenu |
| US11898163B2 (en) | 2016-04-22 | 2024-02-13 | Kyoto University | Method for producing dopaminergic neuron progenitor cell |
| WO2018124118A1 (ja) | 2016-12-27 | 2018-07-05 | 住友化学株式会社 | 人工多能性幹細胞の評価方法及び選抜方法、並びに人工多能性幹細胞の製造方法 |
| EP4053268B1 (en) | 2017-01-20 | 2025-10-08 | Kyoto University | Method for producing cd8alpha+beta+cytotoxic t cells |
| US20210130785A1 (en) | 2017-01-26 | 2021-05-06 | Osaka University | Medium for inducing differentiation of stem cells into mesodermal cells and method for producing mesodermal cells |
| JP7171055B2 (ja) | 2017-03-14 | 2022-11-15 | 国立大学法人京都大学 | 多能性幹細胞からヘルパーt細胞を製造する方法 |
| KR102761727B1 (ko) | 2017-05-25 | 2025-02-03 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 중간 중배엽 세포로부터 신장 전구 세포로의 분화 유도 방법 및 다능성 줄기세포로부터 신장 전구 세포로의 분화 유도 방법 |
| EP3643780A4 (en) | 2017-06-19 | 2021-04-07 | Foundation for Biomedical Research and Innovation at Kobe | METHOD FOR PREDICTING THE DIFFERENTIATION CAPACITY OF PLURIPOTENT STEM CELLS, AND ASSOCIATED REAGENT |
| EP3699267A4 (en) | 2017-10-17 | 2021-10-27 | Kyoto University | PROCESS FOR OBTAINING AN ARTIFICIAL NEUROMUSCULAR JUNCTION FROM PLURIPOTENT STEM CELLS |
| BR112021000437A2 (pt) | 2018-07-13 | 2021-04-06 | Kyoto University | Métodos para produzir uma célula t gama delta e para prevenir ou tratar tumor, célula t gama delta, população de célula, medicamento, agente de extermínio para uma célula, e, uso da célula |
| EP3824912A4 (en) | 2018-07-19 | 2022-04-20 | Kyoto University | PLATEFORM CARTILAGE DERIVED FROM PLURIPOTENTS STEM CELLS AND METHODS FOR PRODUCTION OF PLATEFORM CARTILAGE |
| US20210332329A1 (en) | 2018-07-23 | 2021-10-28 | Kyoto University | Novel renal progenitor cell marker and method for concentrating renal progenitor cells using same |
| US12168781B2 (en) | 2018-12-06 | 2024-12-17 | Kirin Holdings Kabushiki Kaisha | Production method for T cells or NK cells, medium for culturing T cells or NK cells, method for culturing T cells or NK cells, method for maintaining undifferentiated state of undifferentiated T cells, and growth-accelerating agent for T cells or NK cells |
| EP3900787A4 (en) | 2018-12-21 | 2022-02-23 | Kyoto University | LUBRICIN-LOCALIZED CARTILE-LIKE TISSUE, METHOD OF MANUFACTURE THEREOF AND COMPOSITION THEREOF FOR TREATMENT OF ARTICULATE-CARTILAGE DEFECTS |
| CN113226475A (zh) | 2018-12-26 | 2021-08-06 | 麒麟控股株式会社 | 改造tcr及其制造方法 |
| US20220145255A1 (en) | 2019-02-26 | 2022-05-12 | Tohoku University | Method for producing osteoblast cluster using ips cells |
| JP7700673B2 (ja) | 2019-05-15 | 2025-07-01 | 味の素株式会社 | 神経堤細胞または角膜上皮細胞の純化方法 |
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| AU2021225952A1 (en) | 2020-02-28 | 2022-10-20 | Takeda Pharmaceutical Company Limited | Method for producing natural killer cells from pluripotent stem cells |
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| WO2022230977A1 (ja) | 2021-04-30 | 2022-11-03 | 国立研究開発法人理化学研究所 | 網膜色素上皮細胞のひも状凝集体、それを製造するためのデバイスおよび製造方法、ならびに該ひも状凝集体を含有する治療薬 |
| US20240254441A1 (en) | 2021-06-04 | 2024-08-01 | Kirin Holdings Kabushiki Kaisha | Cell composition, method for producing cell composition, and pharmaceutical composition containing cell composition |
| WO2022259721A1 (ja) | 2021-06-10 | 2022-12-15 | 味の素株式会社 | 間葉系幹細胞の製造方法 |
| CN117813374A (zh) | 2021-06-15 | 2024-04-02 | 武田药品工业株式会社 | 从多能干细胞产生自然杀伤细胞的方法 |
| JPWO2023286832A1 (enExample) | 2021-07-15 | 2023-01-19 | ||
| WO2023286834A1 (ja) | 2021-07-15 | 2023-01-19 | アステラス製薬株式会社 | 血管内皮増殖因子(vegf)高発現ペリサイト様細胞 |
| JPWO2023017848A1 (enExample) | 2021-08-11 | 2023-02-16 | ||
| US20250041418A1 (en) | 2021-11-11 | 2025-02-06 | Healios K.K. | Gene-modified pluripotent stem cell, immunocompetent cell derived therefrom, method for producing said cells, and use thereof |
| JPWO2023153464A1 (enExample) | 2022-02-09 | 2023-08-17 | ||
| US20250290076A1 (en) | 2022-04-27 | 2025-09-18 | Kyoto University | Epicardial cell regeneration promoter and method for promoting epicardial cell regeneration |
| US20250376727A1 (en) | 2022-06-10 | 2025-12-11 | Kyoto University | Detection method and detection reagent for undifferentiated pluripotent stem cells |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007069666A1 (ja) * | 2005-12-13 | 2007-06-21 | Kyoto University | 核初期化因子 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| ATE367445T1 (de) | 1999-05-18 | 2007-08-15 | Dnavec Research Inc | Viraler paramyxoviridae vektor mit einem defekten hüllprotein-gen |
| EP2137296A2 (en) * | 2007-03-23 | 2009-12-30 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| CN105861443A (zh) * | 2007-04-07 | 2016-08-17 | 怀特黑德生物医学研究所 | 体细胞重编程 |
| CN101802172A (zh) * | 2007-05-30 | 2010-08-11 | 通用医疗公司 | 由体细胞产生多能细胞的方法 |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| KR101564044B1 (ko) | 2007-10-31 | 2015-10-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 핵초기화 방법 |
| US20110231944A1 (en) | 2008-09-04 | 2011-09-22 | Riken | B cell-derived ips cells and application thereof |
| ES2549155T3 (es) | 2008-09-08 | 2015-10-23 | Riken | Células iPS obtenidas a partir de células NKT y células NKT obtenidas a partir de las mismas |
| KR101764100B1 (ko) | 2009-02-27 | 2017-08-02 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 신규한 핵 재프로그래밍 물질 |
| CN101613717B (zh) | 2009-04-17 | 2012-01-11 | 中国科学院广州生物医药与健康研究院 | 用猪成纤维细胞生成诱导的多能性干细胞的方法 |
| WO2011016588A1 (en) | 2009-08-07 | 2011-02-10 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| JP5765746B2 (ja) | 2010-02-16 | 2015-08-19 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
-
2010
- 2010-02-19 KR KR1020117022584A patent/KR101764100B1/ko active Active
- 2010-02-19 JP JP2011536662A patent/JP5553289B2/ja active Active
- 2010-02-19 EP EP13158495.5A patent/EP2607476B1/en active Active
- 2010-02-19 SG SG2011061959A patent/SG173876A1/en unknown
- 2010-02-19 EP EP10746298A patent/EP2401372A4/en not_active Withdrawn
- 2010-02-19 CN CN201080011401.7A patent/CN102388136B/zh active Active
- 2010-02-19 US US13/203,735 patent/US8951801B2/en active Active
- 2010-02-19 CA CA2753845A patent/CA2753845C/en active Active
- 2010-02-19 WO PCT/JP2010/053024 patent/WO2010098419A1/en not_active Ceased
-
2011
- 2011-08-25 IL IL214833A patent/IL214833A/en active IP Right Grant
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007069666A1 (ja) * | 2005-12-13 | 2007-06-21 | Kyoto University | 核初期化因子 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8951801B2 (en) | 2015-02-10 |
| EP2401372A4 (en) | 2012-09-19 |
| CA2753845C (en) | 2019-10-29 |
| IL214833A0 (en) | 2011-11-30 |
| CN102388136B (zh) | 2014-10-01 |
| US20120052583A1 (en) | 2012-03-01 |
| CN102388136A (zh) | 2012-03-21 |
| EP2607476B1 (en) | 2015-04-08 |
| SG173876A1 (en) | 2011-09-29 |
| IL214833A (en) | 2016-07-31 |
| WO2010098419A1 (en) | 2010-09-02 |
| EP2401372A1 (en) | 2012-01-04 |
| JP5553289B2 (ja) | 2014-07-16 |
| EP2607476A1 (en) | 2013-06-26 |
| KR20120003867A (ko) | 2012-01-11 |
| JP2012518988A (ja) | 2012-08-23 |
| CA2753845A1 (en) | 2010-09-02 |
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