JP2012518404A - Ｃｄ１９に結合するヒト化抗体及びその使用 - Google Patents
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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Applications Claiming Priority (3)
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| US15452409P | 2009-02-23 | 2009-02-23 | |
| US61/154,524 | 2009-02-23 | ||
| PCT/IB2010/000353 WO2010095031A2 (en) | 2009-02-23 | 2010-02-23 | Humanized antibodies that bind to cd19 and their uses |
Publications (2)
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| JP2012518404A true JP2012518404A (ja) | 2012-08-16 |
| JP2012518404A5 JP2012518404A5 (OSRAM) | 2013-04-04 |
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| JP2011550666A Pending JP2012518404A (ja) | 2009-02-23 | 2010-02-23 | Ｃｄ１９に結合するヒト化抗体及びその使用 |
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| US (2) | US8679492B2 (OSRAM) |
| EP (1) | EP2398829A2 (OSRAM) |
| JP (1) | JP2012518404A (OSRAM) |
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| AP (1) | AP2011005859A0 (OSRAM) |
| AU (1) | AU2010215239A1 (OSRAM) |
| BR (1) | BRPI1005984A2 (OSRAM) |
| CA (1) | CA2753158A1 (OSRAM) |
| CL (1) | CL2011002039A1 (OSRAM) |
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| EA (1) | EA201190132A1 (OSRAM) |
| IL (1) | IL214725A0 (OSRAM) |
| MX (1) | MX2011008843A (OSRAM) |
| SG (1) | SG173654A1 (OSRAM) |
| WO (1) | WO2010095031A2 (OSRAM) |
| ZA (1) | ZA201106369B (OSRAM) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013520194A (ja) * | 2010-02-23 | 2013-06-06 | サノフイ | 抗アルファ２インテグリン抗体及びそれらの使用 |
| JP2016514462A (ja) * | 2013-03-16 | 2016-05-23 | ノバルティス アーゲー | ヒト化抗ｃｄ１９キメラ抗原受容体を使用するがんの処置 |
| JP2017500009A (ja) * | 2013-10-31 | 2017-01-05 | フレッド ハッチンソン キャンサー リサーチ センター | 改変された造血幹／前駆細胞及び非エフェクターｔ細胞、そしてそれらの用途 |
| JP2018529733A (ja) * | 2015-10-01 | 2018-10-11 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ヒト化抗ヒトｃｄ１９抗体及び使用方法 |
| JP2018533929A (ja) * | 2015-10-02 | 2018-11-22 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 二重特異性抗ｃｄ１９×ｃｄ３ｔ細胞活性化抗原結合分子 |
| JP2020517302A (ja) * | 2017-04-24 | 2020-06-18 | カイト ファーマ インコーポレイテッドＫｉｔｅ Ｐｈａｒｍａ， Ｉｎｃ | Ｃｄ１９に対するヒト化抗原結合ドメイン及び使用方法 |
| JP2020519285A (ja) * | 2017-05-10 | 2020-07-02 | ザ ウィスター インスティテュート オブ アナトミー アンド バイオロジー | 最適化された核酸抗体構築物 |
| JP2022028645A (ja) * | 2018-12-21 | 2022-02-16 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | Ｃｄ３に結合する抗体 |
| US11780920B2 (en) | 2020-06-19 | 2023-10-10 | Hoffmann-La Roche Inc. | Antibodies binding to CD3 and CD19 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI560199B (en) | 2010-08-31 | 2016-12-01 | Sanofi Sa | Peptide or peptide complex binding to α2 integrin and methods and uses involving the same |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| WO2012096975A2 (en) * | 2011-01-13 | 2012-07-19 | The Board Of Trustees Of The Leland Stanford Junior University | Method of predicting responsiveness of b cell lineage malignancies to active immunotherapy |
| SG10201602371VA (en) | 2011-03-25 | 2016-04-28 | Glenmark Pharmaceuticals Sa | Hetero-dimeric immunoglobulins |
| EA036047B1 (ru) | 2011-07-11 | 2020-09-18 | Икнос Сайенсиз Са | Антитела, которые связываются с ox40, и их применение |
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2753158A1 (en) | 2010-08-26 |
| IL214725A0 (en) | 2011-11-30 |
| WO2010095031A3 (en) | 2010-11-04 |
| CN102421800A (zh) | 2012-04-18 |
| CO6430469A2 (es) | 2012-04-30 |
| EP2398829A2 (en) | 2011-12-28 |
| SG173654A1 (en) | 2011-09-29 |
| KR20110122859A (ko) | 2011-11-11 |
| US20140286934A1 (en) | 2014-09-25 |
| AU2010215239A1 (en) | 2011-09-15 |
| ZA201106369B (en) | 2012-05-30 |
| AP2011005859A0 (en) | 2011-10-31 |
| BRPI1005984A2 (pt) | 2016-10-04 |
| WO2010095031A2 (en) | 2010-08-26 |
| US8679492B2 (en) | 2014-03-25 |
| MX2011008843A (es) | 2011-12-14 |
| EA201190132A1 (ru) | 2013-01-30 |
| CL2011002039A1 (es) | 2012-03-30 |
| US20100215651A1 (en) | 2010-08-26 |
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