JP2012507538A5 - - Google Patents

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Publication number
JP2012507538A5
JP2012507538A5 JP2011534650A JP2011534650A JP2012507538A5 JP 2012507538 A5 JP2012507538 A5 JP 2012507538A5 JP 2011534650 A JP2011534650 A JP 2011534650A JP 2011534650 A JP2011534650 A JP 2011534650A JP 2012507538 A5 JP2012507538 A5 JP 2012507538A5
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JP
Japan
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methyl
carboxamide
bipyridine
dimethoxypyridin
fluorophenyl
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JP2011534650A
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English (en)
Japanese (ja)
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JP5635991B2 (ja
JP2012507538A (ja
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Priority claimed from PCT/US2009/061987 external-priority patent/WO2010051236A1/en
Publication of JP2012507538A publication Critical patent/JP2012507538A/ja
Publication of JP2012507538A5 publication Critical patent/JP2012507538A5/ja
Application granted granted Critical
Publication of JP5635991B2 publication Critical patent/JP5635991B2/ja
Expired - Fee Related legal-status Critical Current
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JP2011534650A 2008-10-30 2009-10-26 イソニコチンアミドオレキシン受容体アンタゴニスト Expired - Fee Related JP5635991B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19778908P 2008-10-30 2008-10-30
US61/197,789 2008-10-30
US18057409P 2009-05-22 2009-05-22
US61/180,574 2009-05-22
PCT/US2009/061987 WO2010051236A1 (en) 2008-10-30 2009-10-26 Isonicotinamide orexin receptor antagonists

Publications (3)

Publication Number Publication Date
JP2012507538A JP2012507538A (ja) 2012-03-29
JP2012507538A5 true JP2012507538A5 (enExample) 2012-12-13
JP5635991B2 JP5635991B2 (ja) 2014-12-03

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JP2011534650A Expired - Fee Related JP5635991B2 (ja) 2008-10-30 2009-10-26 イソニコチンアミドオレキシン受容体アンタゴニスト

Country Status (23)

Country Link
US (1) US8592457B2 (enExample)
EP (1) EP2350010B1 (enExample)
JP (1) JP5635991B2 (enExample)
KR (1) KR101320245B1 (enExample)
CN (1) CN102272103B (enExample)
AU (1) AU2009308980B2 (enExample)
BR (1) BRPI0919876A8 (enExample)
CA (1) CA2741644C (enExample)
CL (1) CL2011000976A1 (enExample)
CO (1) CO6361994A2 (enExample)
CR (1) CR20110228A (enExample)
DO (1) DOP2011000120A (enExample)
EA (1) EA201170624A1 (enExample)
EC (1) ECSP11011019A (enExample)
IL (1) IL212436A0 (enExample)
MA (1) MA32804B1 (enExample)
MX (1) MX2011004551A (enExample)
NI (1) NI201100084A (enExample)
NZ (1) NZ592544A (enExample)
PE (1) PE20110852A1 (enExample)
TN (1) TN2011000171A1 (enExample)
WO (1) WO2010051236A1 (enExample)
ZA (1) ZA201103156B (enExample)

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CN104350053B (zh) * 2012-06-15 2017-03-08 大正制药株式会社 杂芳族甲基环胺衍生物
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WO2016101118A1 (en) 2014-12-23 2016-06-30 Merck Sharp & Dohme Corp. Amidoethyl azole orexin receptor antagonists
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JP6936224B2 (ja) 2015-11-23 2021-09-15 サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. オクタヒドロピロロ[3,4−c]ピロール誘導体およびその使用
SI3414241T1 (sl) 2016-02-12 2022-10-28 Astrazeneca Ab Halo-substituitani piperidini kot modulatorji receptorja oreksina
SI3426251T1 (sl) 2016-03-10 2022-07-29 Janssen Pharmaceutica Nv Postopki za zdravljenje depresije z antagonisti receptorja oreksina-2
GB201702174D0 (en) 2017-02-09 2017-03-29 Benevolentai Bio Ltd Orexin receptor antagonists
GB201707504D0 (en) 2017-05-10 2017-06-21 Benevolentai Bio Ltd Orexin receptor antagonists
GB201707499D0 (en) 2017-05-10 2017-06-21 Benevolentai Bio Ltd Orexin receptor antagonists
CN109280027A (zh) * 2018-12-13 2019-01-29 康化(上海)新药研发有限公司 一种5,6-二甲氧基-2-吡啶甲酸的合成方法
CN116600803A (zh) * 2020-11-02 2023-08-15 默沙东有限责任公司 大环脲食欲素受体激动剂

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