SI3340971T1 - Metode zdravljenja lennox-gastautovega sindroma z uporabo fenfluramina - Google Patents
Metode zdravljenja lennox-gastautovega sindroma z uporabo fenfluraminaInfo
- Publication number
- SI3340971T1 SI3340971T1 SI201631816T SI201631816T SI3340971T1 SI 3340971 T1 SI3340971 T1 SI 3340971T1 SI 201631816 T SI201631816 T SI 201631816T SI 201631816 T SI201631816 T SI 201631816T SI 3340971 T1 SI3340971 T1 SI 3340971T1
- Authority
- SI
- Slovenia
- Prior art keywords
- fenfluramine
- methods
- gastaut syndrome
- lennox
- treating
- Prior art date
Links
- DBGIVFWFUFKIQN-UHFFFAOYSA-N (+-)-Fenfluramine Chemical compound CCNC(C)CC1=CC=CC(C(F)(F)F)=C1 DBGIVFWFUFKIQN-UHFFFAOYSA-N 0.000 title 1
- 201000006792 Lennox-Gastaut syndrome Diseases 0.000 title 1
- 229960001582 fenfluramine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paper (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562209090P | 2015-08-24 | 2015-08-24 | |
PCT/US2016/048470 WO2017035267A1 (en) | 2015-08-24 | 2016-08-24 | Methods of treating lennox-gastaut syndrome using fenfluramine |
EP16840062.0A EP3340971B1 (en) | 2015-08-24 | 2016-08-24 | Methods of treating lennox-gastaut syndrome using fenfluramine |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3340971T1 true SI3340971T1 (sl) | 2024-05-31 |
Family
ID=58101064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201631816T SI3340971T1 (sl) | 2015-08-24 | 2016-08-24 | Metode zdravljenja lennox-gastautovega sindroma z uporabo fenfluramina |
Country Status (17)
Country | Link |
---|---|
US (2) | US20170056344A1 (sl) |
EP (1) | EP3340971B1 (sl) |
JP (1) | JP6895949B2 (sl) |
KR (3) | KR102615486B1 (sl) |
CN (3) | CN115350168A (sl) |
AU (1) | AU2016312526B2 (sl) |
BR (1) | BR112018002046A2 (sl) |
CA (1) | CA2993665C (sl) |
DK (1) | DK3340971T3 (sl) |
FI (1) | FI3340971T3 (sl) |
IL (1) | IL257276B (sl) |
LT (1) | LT3340971T (sl) |
MX (1) | MX2018001435A (sl) |
RU (1) | RU2740919C2 (sl) |
SI (1) | SI3340971T1 (sl) |
WO (1) | WO2017035267A1 (sl) |
ZA (1) | ZA201800499B (sl) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10647465B2 (en) | 2010-11-12 | 2020-05-12 | Niagara Bottling, Llc | Perform extended finish for processing light weight ecologically beneficial bottles |
EP2637831B1 (en) | 2010-11-12 | 2018-09-05 | Niagara Bottling, LLC | Preform extended finish for processing light weight bottles |
US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
KR20180095674A (ko) | 2015-12-22 | 2018-08-27 | 조게닉스 인터내셔널 리미티드 | 대사 저항성 펜플루라민 유사체 및 그 사용 방법 |
CN108883399B (zh) | 2015-12-22 | 2021-06-22 | 周格尼克斯国际有限公司 | 芬氟拉明组合物及其制备方法 |
WO2018037306A1 (en) | 2016-08-24 | 2018-03-01 | Zogenix International Limited | Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same |
US20180092864A1 (en) * | 2016-09-30 | 2018-04-05 | Zogenix International Limited | Compositions and methods for treating seizure disorders |
AU2018265353A1 (en) * | 2017-05-09 | 2019-11-21 | Zogenix International Limited | Methods of treating Doose syndrome using fenfluramine |
US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
US20190091179A1 (en) * | 2017-09-26 | 2019-03-28 | Zogenix International Limited | Congnitive function with fenfluramine |
GB201715919D0 (en) * | 2017-09-29 | 2017-11-15 | Gw Res Ltd | use of cannabinoids in the treatment of epilepsy |
WO2019216919A1 (en) * | 2018-05-11 | 2019-11-14 | Zogenix International Limited | Compositions and methods for treating seizure-induced sudden death |
WO2019241005A1 (en) | 2018-06-14 | 2019-12-19 | Zogenix International Limited | Compositions and methods for treating respiratory depression with fenfluramine |
JP2021530481A (ja) * | 2018-07-10 | 2021-11-11 | ゾゲニクス インターナショナル リミテッド | 肺高血圧症を有さない患者においててんかんまたはてんかん性脳症を処置するために使用するためのフェンフルラミン |
US11597556B2 (en) | 2018-07-30 | 2023-03-07 | Niagara Bottling, Llc | Container preform with tamper evidence finish portion |
EA202191079A1 (ru) * | 2018-11-19 | 2021-09-20 | Зодженикс Интернэшнл Лимитед | Способы лечения синдрома ретта с применением фенфлурамина |
US20220133652A1 (en) * | 2019-02-25 | 2022-05-05 | Zogenix International Limited | A formulation for improving seizure control |
JP2022548892A (ja) | 2019-09-17 | 2022-11-22 | ゾゲニクス インターナショナル リミテッド | てんかん患者をフェンフルラミンで治療する方法 |
US20210299064A1 (en) * | 2020-02-05 | 2021-09-30 | Zogenix International Limited | Method of treating patients with lennox-gastaut syndrome |
US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1888030A1 (en) * | 2005-05-25 | 2008-02-20 | Janssen Pharmaceutica N.V. | Pediatric formulation of topiramate |
US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
GB0515090D0 (en) * | 2005-07-22 | 2005-08-31 | Birmingham Res & Dev Ltd | Novel epilepsy treatment |
BRPI0919876A8 (pt) * | 2008-10-30 | 2016-02-10 | Merck Sharp & Dohme | Composto, composição farmacêutica, uso de um composto, e, método para intensificar a qualidade do sono, para tratar insônia, e para tratar ou controlar obesidade em um paciente mamífero que necessita do mesmo. |
AR079862A1 (es) * | 2010-01-08 | 2012-02-22 | Eurand Inc | Composicion de topiramato con sabor enmascarado, un comprimido desintegrable oralmente que comprende la misma y metodo de preparacion |
CA2796963A1 (en) * | 2010-04-23 | 2011-10-27 | Piramal Enterprises Limited | Nitric oxide releasing prodrugs of therapeutic agents |
US9549909B2 (en) * | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
SI3035926T1 (sl) * | 2013-08-19 | 2020-11-30 | The Regents Of The University Of California | Spojine in postopki za zdravljenje epileptičnih motenj |
-
2016
- 2016-08-24 LT LTEPPCT/US2016/048470T patent/LT3340971T/lt unknown
- 2016-08-24 CN CN202211037242.9A patent/CN115350168A/zh active Pending
- 2016-08-24 AU AU2016312526A patent/AU2016312526B2/en active Active
- 2016-08-24 KR KR1020227045101A patent/KR102615486B1/ko active IP Right Grant
- 2016-08-24 WO PCT/US2016/048470 patent/WO2017035267A1/en active Application Filing
- 2016-08-24 BR BR112018002046A patent/BR112018002046A2/pt not_active Application Discontinuation
- 2016-08-24 RU RU2018108202A patent/RU2740919C2/ru active
- 2016-08-24 US US15/246,346 patent/US20170056344A1/en not_active Abandoned
- 2016-08-24 CN CN202210746238.3A patent/CN115192575A/zh active Pending
- 2016-08-24 SI SI201631816T patent/SI3340971T1/sl unknown
- 2016-08-24 KR KR1020187005840A patent/KR20180054584A/ko not_active IP Right Cessation
- 2016-08-24 JP JP2018510511A patent/JP6895949B2/ja active Active
- 2016-08-24 DK DK16840062.0T patent/DK3340971T3/da active
- 2016-08-24 EP EP16840062.0A patent/EP3340971B1/en active Active
- 2016-08-24 KR KR1020227005011A patent/KR102481631B1/ko active IP Right Grant
- 2016-08-24 CN CN201680049517.7A patent/CN108135865A/zh active Pending
- 2016-08-24 MX MX2018001435A patent/MX2018001435A/es unknown
- 2016-08-24 CA CA2993665A patent/CA2993665C/en active Active
- 2016-08-24 FI FIEP16840062.0T patent/FI3340971T3/fi active
-
2018
- 2018-01-24 ZA ZA2018/00499A patent/ZA201800499B/en unknown
- 2018-01-31 IL IL257276A patent/IL257276B/en unknown
-
2020
- 2020-05-01 US US16/864,955 patent/US20200253895A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
LT3340971T (lt) | 2024-04-25 |
ZA201800499B (en) | 2018-12-19 |
CN115350168A (zh) | 2022-11-18 |
KR20220025927A (ko) | 2022-03-03 |
CA2993665A1 (en) | 2017-03-02 |
MX2018001435A (es) | 2018-04-20 |
AU2016312526A1 (en) | 2018-02-22 |
WO2017035267A1 (en) | 2017-03-02 |
IL257276A (en) | 2018-03-29 |
US20200253895A1 (en) | 2020-08-13 |
EP3340971A1 (en) | 2018-07-04 |
DK3340971T3 (da) | 2024-05-27 |
KR20230005426A (ko) | 2023-01-09 |
BR112018002046A2 (pt) | 2018-09-18 |
KR20180054584A (ko) | 2018-05-24 |
JP6895949B2 (ja) | 2021-06-30 |
CA2993665C (en) | 2023-03-07 |
KR102481631B1 (ko) | 2022-12-27 |
AU2016312526B2 (en) | 2021-09-09 |
KR102615486B1 (ko) | 2023-12-19 |
IL257276B (en) | 2022-06-01 |
US20170056344A1 (en) | 2017-03-02 |
CN115192575A (zh) | 2022-10-18 |
RU2740919C2 (ru) | 2021-01-21 |
CN108135865A (zh) | 2018-06-08 |
RU2018108202A (ru) | 2019-09-26 |
RU2018108202A3 (sl) | 2020-01-20 |
JP2018525418A (ja) | 2018-09-06 |
EP3340971B1 (en) | 2024-03-13 |
EP3340971A4 (en) | 2019-05-01 |
FI3340971T3 (fi) | 2024-06-10 |
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