JP2012112042A5 - - Google Patents
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- Publication number
- JP2012112042A5 JP2012112042A5 JP2011240752A JP2011240752A JP2012112042A5 JP 2012112042 A5 JP2012112042 A5 JP 2012112042A5 JP 2011240752 A JP2011240752 A JP 2011240752A JP 2011240752 A JP2011240752 A JP 2011240752A JP 2012112042 A5 JP2012112042 A5 JP 2012112042A5
- Authority
- JP
- Japan
- Prior art keywords
- gold nanoparticles
- acid
- blue
- organic acid
- blue gold
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 51
- 239000010931 gold Substances 0.000 claims description 51
- 229910052737 gold Inorganic materials 0.000 claims description 51
- 239000002105 nanoparticle Substances 0.000 claims description 51
- 150000007524 organic acids Chemical class 0.000 claims description 18
- 238000004519 manufacturing process Methods 0.000 claims description 13
- 239000000126 substance Substances 0.000 claims description 9
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 8
- 239000006173 Good's buffer Substances 0.000 claims description 8
- 230000001900 immune effect Effects 0.000 claims description 8
- 238000002372 labelling Methods 0.000 claims description 8
- 125000004193 piperazinyl group Chemical group 0.000 claims description 8
- 230000001603 reducing effect Effects 0.000 claims description 8
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 238000005259 measurement Methods 0.000 claims description 6
- 239000002245 particle Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- JAJIPIAHCFBEPI-UHFFFAOYSA-N 9,10-dioxoanthracene-1-sulfonic acid Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C=CC=C2S(=O)(=O)O JAJIPIAHCFBEPI-UHFFFAOYSA-N 0.000 claims description 4
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 4
- 235000010323 ascorbic acid Nutrition 0.000 claims description 4
- 239000011668 ascorbic acid Substances 0.000 claims description 4
- 238000006243 chemical reaction Methods 0.000 claims description 4
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 claims description 3
- 239000001263 FEMA 3042 Substances 0.000 claims description 3
- OWXMKDGYPWMGEB-UHFFFAOYSA-N HEPPS Chemical compound OCCN1CCN(CCCS(O)(=O)=O)CC1 OWXMKDGYPWMGEB-UHFFFAOYSA-N 0.000 claims description 3
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 claims description 3
- 229940033123 tannic acid Drugs 0.000 claims description 3
- 235000015523 tannic acid Nutrition 0.000 claims description 3
- 229920002258 tannic acid Polymers 0.000 claims description 3
- IHPYMWDTONKSCO-UHFFFAOYSA-N 2,2'-piperazine-1,4-diylbisethanesulfonic acid Chemical compound OS(=O)(=O)CCN1CCN(CCS(O)(=O)=O)CC1 IHPYMWDTONKSCO-UHFFFAOYSA-N 0.000 claims description 2
- HSXUNHYXJWDLDK-UHFFFAOYSA-N 2-hydroxypropane-1-sulfonic acid Chemical compound CC(O)CS(O)(=O)=O HSXUNHYXJWDLDK-UHFFFAOYSA-N 0.000 claims description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 2
- GIZQLVPDAOBAFN-UHFFFAOYSA-N HEPPSO Chemical compound OCCN1CCN(CC(O)CS(O)(=O)=O)CC1 GIZQLVPDAOBAFN-UHFFFAOYSA-N 0.000 claims description 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 2
- 238000010521 absorption reaction Methods 0.000 claims description 2
- 238000000862 absorption spectrum Methods 0.000 claims description 2
- 229940072107 ascorbate Drugs 0.000 claims description 2
- 229960005070 ascorbic acid Drugs 0.000 claims description 2
- 229940001468 citrate Drugs 0.000 claims description 2
- 229960004106 citric acid Drugs 0.000 claims description 2
- 235000015165 citric acid Nutrition 0.000 claims description 2
- 239000000084 colloidal system Substances 0.000 claims description 2
- 238000000691 measurement method Methods 0.000 claims description 2
- 230000006911 nucleation Effects 0.000 claims description 2
- 238000010899 nucleation Methods 0.000 claims description 2
- 239000011975 tartaric acid Substances 0.000 claims description 2
- 229960001367 tartaric acid Drugs 0.000 claims description 2
- 235000002906 tartaric acid Nutrition 0.000 claims description 2
- 229940095064 tartrate Drugs 0.000 claims description 2
- LRBQNJMCXXYXIU-QWKBTXIPSA-N gallotannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@H]2[C@@H]([C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-QWKBTXIPSA-N 0.000 claims 2
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical group OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 description 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 description 1
- 229920002253 Tannate Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- KCXFHTAICRTXLI-UHFFFAOYSA-N propane-1-sulfonic acid Chemical compound CCCS(O)(=O)=O KCXFHTAICRTXLI-UHFFFAOYSA-N 0.000 description 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011240752A JP5358648B2 (ja) | 2010-11-05 | 2011-11-02 | 免疫学的測定用青色金ナノ粒子、その製造方法およびそれを用いた測定方法 |
| US13/883,213 US9360431B2 (en) | 2010-11-05 | 2011-11-04 | Blue-colored gold nanoparticles for immunological measurement, process for production of same, and measurement method using same |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010248463 | 2010-11-05 | ||
| JP2010248463 | 2010-11-05 | ||
| JP2011240752A JP5358648B2 (ja) | 2010-11-05 | 2011-11-02 | 免疫学的測定用青色金ナノ粒子、その製造方法およびそれを用いた測定方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012112042A JP2012112042A (ja) | 2012-06-14 |
| JP2012112042A5 true JP2012112042A5 (enExample) | 2012-07-26 |
| JP5358648B2 JP5358648B2 (ja) | 2013-12-04 |
Family
ID=46024568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011240752A Active JP5358648B2 (ja) | 2010-11-05 | 2011-11-02 | 免疫学的測定用青色金ナノ粒子、その製造方法およびそれを用いた測定方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9360431B2 (enExample) |
| EP (1) | EP2636469A4 (enExample) |
| JP (1) | JP5358648B2 (enExample) |
| KR (1) | KR101729810B1 (enExample) |
| CN (1) | CN103201057B (enExample) |
| AU (2) | AU2011324320B2 (enExample) |
| CA (1) | CA2816674C (enExample) |
| IL (1) | IL226071A (enExample) |
| WO (1) | WO2012060456A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103990813B (zh) * | 2014-06-09 | 2016-10-19 | 谢雅聪 | 一种金纳米线的制备方法 |
| JP6660934B2 (ja) * | 2015-02-25 | 2020-03-11 | 積水メディカル株式会社 | 免疫学的測定方法及び該方法に用いられる測定試薬 |
| CN105203750B (zh) * | 2015-09-22 | 2016-10-05 | 福州大学 | 一种酶联免疫分析定量方法 |
| AU2017207860A1 (en) * | 2016-01-15 | 2018-06-28 | Dsm Ip Assets B.V. | Method for detecting an analyte |
| CN105891468A (zh) * | 2016-04-08 | 2016-08-24 | 四川新健康成生物股份有限公司 | 一种样品释放垫处理液 |
| CN106636405B (zh) * | 2016-12-26 | 2021-01-05 | 中国科学院长春光学精密机械与物理研究所 | 一种核酸检测的复合物及其制备方法与核酸检测的方法 |
| SG11201903913QA (en) * | 2017-01-12 | 2019-05-30 | Agency Science Tech & Res | A method of detecting the presence of different target analytes and related kits thereof |
| JP7223222B2 (ja) * | 2018-09-21 | 2023-02-16 | 国立大学法人山梨大学 | ヒドロキシ酸還元型金ナノ粒子を用いたアミノ酸の色調変化による選択的検出と不斉識別 |
| EP3656826B1 (en) * | 2018-11-22 | 2021-05-19 | Société BIC | Process for preparing aqueous gel inks with fixed color, and aqueous gel inks thereof |
| JP7258698B2 (ja) * | 2019-09-06 | 2023-04-17 | 大日本塗料株式会社 | 粒状物質をイムノクロマトグラフィー法によって検出する方法及びそのためのキット |
| CN110524005B (zh) * | 2019-09-24 | 2022-06-07 | 苏州大学 | 一种支化钯银铂纳米环及其制备方法 |
| CN112191859A (zh) * | 2020-09-29 | 2021-01-08 | 石河子大学 | 一种贵金属纳米溶胶及其制备方法和应用 |
| CN116420066A (zh) * | 2020-10-23 | 2023-07-11 | 滋吾堂有限公司 | 目标物质的检测方法和装置、以及试剂 |
| CN116409940B (zh) * | 2023-03-21 | 2024-10-15 | 江苏理工学院 | 一种用于折射率传感的金纳米颗粒薄膜的制备方法 |
| CN119346885B (zh) * | 2024-12-25 | 2025-06-17 | 长春黄金研究院有限公司 | 高球形度的纳米金溶胶及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6116602A (ja) | 1984-07-03 | 1986-01-24 | Sony Corp | 入力回路 |
| JP3658890B2 (ja) | 1996-11-01 | 2005-06-08 | 松下電器産業株式会社 | 標識抗体粒子及びそれを用いた測定装置 |
| JP3886000B2 (ja) | 2002-03-08 | 2007-02-28 | 株式会社ビーエル | 金属コロイド粒子 |
| JP4180531B2 (ja) | 2004-02-19 | 2008-11-12 | 日本板硝子株式会社 | 金属コロイド粒子及びその製造方法 |
| US20050287680A1 (en) * | 2004-06-25 | 2005-12-29 | Srivatsa Venkatasubbarao | Multianalyte assay method |
| JP4529160B2 (ja) | 2004-07-08 | 2010-08-25 | 三菱マテリアル株式会社 | 金属微粒子とその製造方法とその含有組成物ならびにその用途 |
| JP4792573B2 (ja) * | 2005-02-28 | 2011-10-12 | 国立大学法人埼玉大学 | ナノ粒子生成方法及びレーザカラーマーキング方法 |
| KR100620615B1 (ko) | 2005-05-23 | 2006-09-06 | 한국생명공학연구원 | 가시광선 영역의 색을 갖는 금속 나노입자 혼합물이 코팅된 다색 콜로이드 입자 및 그 제조방법 |
| KR100732249B1 (ko) | 2005-07-18 | 2007-06-27 | 한국생명공학연구원 | 금 및/또는 은 나노입자를 함유하는 화장료용 안료 조성물 |
| US20070110671A1 (en) * | 2005-11-14 | 2007-05-17 | Danielle Chamberlin | Sensitivity enhancement of POCT devices using gold and silver nanoparticles on patterned substrates |
| JP4970851B2 (ja) | 2006-06-05 | 2012-07-11 | 田中貴金属工業株式会社 | 金コロイドの製造方法及び金コロイド |
| JP5431644B2 (ja) | 2006-12-28 | 2014-03-05 | シスメックス株式会社 | 呼吸器感染症の検査方法 |
| JP2009144196A (ja) * | 2007-12-13 | 2009-07-02 | Hiroshima Univ | 金属粒子、金粒子の製造方法および光記録媒体 |
| JP5035622B2 (ja) * | 2008-01-11 | 2012-09-26 | 積水化学工業株式会社 | 着色ラテックス |
| JP5623048B2 (ja) | 2009-03-25 | 2014-11-12 | 富士フイルム株式会社 | 潤滑剤組成物、及びその用途 |
| JP2011016778A (ja) * | 2009-07-10 | 2011-01-27 | Shiga Univ Of Medical Science | 金ナノ粒子組成物、ｄｎａチップ、近赤外線吸収材、ドラッグデリバリーシステム（ｄｄｓ）用薬物保持体、着色剤、バイオセンサー、化粧品、生体内診断用組成物および治療用組成物。 |
| JP5581480B2 (ja) * | 2010-02-09 | 2014-09-03 | 株式会社新光化学工業所 | 金属ナノ粒子クラスター、金属ナノ粒子クラスターを用いた標識材料、金属ナノ粒子クラスターを用いたイムノクロマトグラフィーキット、金属ナノ粒子クラスターの製造方法、金属ナノ粒子クラスターを用いた標識材料の製造方法および金属ナノ粒子クラスターを用いたイムノクロマトグラフィーキットの製造方法。 |
-
2011
- 2011-11-02 JP JP2011240752A patent/JP5358648B2/ja active Active
- 2011-11-04 WO PCT/JP2011/075519 patent/WO2012060456A1/ja not_active Ceased
- 2011-11-04 KR KR1020137013805A patent/KR101729810B1/ko active Active
- 2011-11-04 AU AU2011324320A patent/AU2011324320B2/en not_active Ceased
- 2011-11-04 US US13/883,213 patent/US9360431B2/en active Active
- 2011-11-04 EP EP11838106.0A patent/EP2636469A4/en not_active Withdrawn
- 2011-11-04 CN CN201180053388.6A patent/CN103201057B/zh not_active Expired - Fee Related
- 2011-11-04 CA CA2816674A patent/CA2816674C/en not_active Expired - Fee Related
-
2013
- 2013-04-30 IL IL226071A patent/IL226071A/en active IP Right Grant
-
2016
- 2016-08-19 AU AU2016216707A patent/AU2016216707B2/en not_active Ceased
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