JP2012006969A5 - - Google Patents
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- Publication number
- JP2012006969A5 JP2012006969A5 JP2011198277A JP2011198277A JP2012006969A5 JP 2012006969 A5 JP2012006969 A5 JP 2012006969A5 JP 2011198277 A JP2011198277 A JP 2011198277A JP 2011198277 A JP2011198277 A JP 2011198277A JP 2012006969 A5 JP2012006969 A5 JP 2012006969A5
- Authority
- JP
- Japan
- Prior art keywords
- immunogenic composition
- protein
- antigen
- group
- adjuvant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000036639 antigens Human genes 0.000 claims 13
- 108091007433 antigens Proteins 0.000 claims 13
- 230000002163 immunogen Effects 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 12
- 150000004676 glycans Chemical class 0.000 claims 10
- 229920001282 polysaccharide Polymers 0.000 claims 10
- 239000005017 polysaccharide Substances 0.000 claims 10
- 239000002671 adjuvant Substances 0.000 claims 9
- 241000193998 Streptococcus pneumoniae Species 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 8
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims 8
- 101100453077 Botryococcus braunii HDR gene Proteins 0.000 claims 6
- 238000000034 method Methods 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 229960005486 vaccine Drugs 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 206010033078 Otitis media Diseases 0.000 claims 2
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims 2
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 2
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims 1
- 102000014914 Carrier Proteins Human genes 0.000 claims 1
- 108010078791 Carrier Proteins Proteins 0.000 claims 1
- 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 101710188053 Protein D Proteins 0.000 claims 1
- 101710132893 Resolvase Proteins 0.000 claims 1
- 241000194017 Streptococcus Species 0.000 claims 1
- 229960003983 diphtheria toxoid Drugs 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 239000000411 inducer Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 208000037800 influenza D Diseases 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims 1
- 229930182490 saponin Natural products 0.000 claims 1
- 150000007949 saponins Chemical class 0.000 claims 1
- 229960000814 tetanus toxoid Drugs 0.000 claims 1
- 229960001005 tuberculin Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0022742.1A GB0022742D0 (en) | 2000-09-15 | 2000-09-15 | Vaccine |
| GB0022742.1 | 2000-09-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002526416A Division JP4903975B2 (ja) | 2000-09-15 | 2001-09-12 | ワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012006969A JP2012006969A (ja) | 2012-01-12 |
| JP2012006969A5 true JP2012006969A5 (enExample) | 2012-12-06 |
Family
ID=9899575
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002526416A Expired - Fee Related JP4903975B2 (ja) | 2000-09-15 | 2001-09-12 | ワクチン |
| JP2002526417A Expired - Fee Related JP4880184B2 (ja) | 2000-09-15 | 2001-09-12 | ワクチン |
| JP2011198277A Pending JP2012006969A (ja) | 2000-09-15 | 2011-09-12 | ワクチン |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002526416A Expired - Fee Related JP4903975B2 (ja) | 2000-09-15 | 2001-09-12 | ワクチン |
| JP2002526417A Expired - Fee Related JP4880184B2 (ja) | 2000-09-15 | 2001-09-12 | ワクチン |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US20060051361A1 (enExample) |
| EP (6) | EP2305298A1 (enExample) |
| JP (3) | JP4903975B2 (enExample) |
| KR (5) | KR101268790B1 (enExample) |
| CN (3) | CN100486642C (enExample) |
| AT (1) | ATE516815T1 (enExample) |
| AU (4) | AU2002238193B2 (enExample) |
| BR (2) | BR0113822A (enExample) |
| CA (2) | CA2422002C (enExample) |
| CY (1) | CY1111915T1 (enExample) |
| CZ (2) | CZ305324B6 (enExample) |
| DK (1) | DK1317279T3 (enExample) |
| ES (4) | ES2659400T3 (enExample) |
| GB (1) | GB0022742D0 (enExample) |
| HU (2) | HUP0301043A3 (enExample) |
| IL (4) | IL154608A0 (enExample) |
| MX (2) | MXPA03002264A (enExample) |
| NO (2) | NO336186B1 (enExample) |
| NZ (2) | NZ524287A (enExample) |
| PL (2) | PL210198B1 (enExample) |
| PT (1) | PT1317279E (enExample) |
| SI (1) | SI1317279T1 (enExample) |
| WO (2) | WO2002022167A2 (enExample) |
| ZA (2) | ZA200301524B (enExample) |
Families Citing this family (75)
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|---|---|---|---|---|
| US7078042B2 (en) * | 1995-09-15 | 2006-07-18 | Uab Research Foundation | Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor |
| US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US7098023B1 (en) | 1997-07-02 | 2006-08-29 | Sanofi Pasteur Limited | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US20010016200A1 (en) | 1998-04-23 | 2001-08-23 | Briles David E. | Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor |
| US7128918B1 (en) * | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| MY125387A (en) * | 1999-03-19 | 2006-07-31 | Smithkline Beecham Biologicals S A | Vaccine |
| US7074415B2 (en) * | 2000-06-20 | 2006-07-11 | Id Biomedical Corporation | Streptococcus antigens |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| EP1456231A2 (en) | 2001-12-20 | 2004-09-15 | Shire Biochem Inc. | Streptococcus antigens |
| US8691243B2 (en) | 2002-04-02 | 2014-04-08 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based Streptococcus pneumoniae vaccine |
| EP2275120A3 (en) * | 2002-04-02 | 2011-06-08 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based streptococcus pneumoniae vaccines |
| US8663656B2 (en) | 2002-10-11 | 2014-03-04 | Novartis Ag | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| US8229903B2 (en) * | 2002-12-19 | 2012-07-24 | International Business Machines Corporation | Suggesting data interpretations and patterns for updating policy documents |
| CA3042073C (en) | 2003-01-30 | 2022-09-13 | Novartis Vaccines And Diagnostics S.R.L. | Injectable vaccines against multiple meningococcal serogroups |
| WO2004081515A2 (en) * | 2003-03-13 | 2004-09-23 | Glaxosmithkline Biologicals S.A. | Purification process for bacterial cytolysin |
| EP1477802A1 (en) * | 2003-05-16 | 2004-11-17 | Erasmus Universiteit Rotterdam | Method for selecting and producing vaccine components and vaccines based thereon |
| SI1670506T1 (sl) | 2003-10-02 | 2013-03-29 | Novartis Ag | Tekoča cepiva proti multiplim meningokoknim seroskupinam |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| CA2580693A1 (en) * | 2004-09-21 | 2006-03-30 | Sanofi Pasteur, Inc. | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine |
| AU2011253684B8 (en) * | 2005-04-08 | 2013-07-11 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| KR102017842B1 (ko) * | 2005-04-08 | 2019-09-03 | 와이어쓰 엘엘씨 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| GB0522765D0 (en) | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| EA014107B1 (ru) | 2005-12-22 | 2010-10-29 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae |
| DK1976974T3 (da) * | 2005-12-28 | 2014-09-15 | Uab Research Foundation | Pneumokok-serotyper. |
| US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
| MX2009001778A (es) * | 2006-08-17 | 2009-05-22 | Uab Research Foundation | Peptidos pcpa inmunogenicos y usos de los mismos. |
| US20090035360A1 (en) * | 2007-05-24 | 2009-02-05 | Dominique Ingrid Lemoine | Lyophilised antigen composition |
| BRPI0813644B8 (pt) | 2007-06-26 | 2021-05-25 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, processo para fabricar a mesma, e, uso da composição imunogênica ou vacina |
| GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
| KR101595234B1 (ko) | 2007-07-23 | 2016-02-26 | 사노피 파스퇴르 리미티드 | 면역원성 폴리펩타이드 및 단일클론 항체 |
| US20160228500A9 (en) * | 2007-07-23 | 2016-08-11 | Martina Ochs | Immunogenic Polypeptides and Monoclonal Antibodies |
| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| US20100278819A1 (en) * | 2007-09-14 | 2010-11-04 | Katholieke Universiteit Leuven | Streptococcus pneumoniae vaccines |
| JP5697991B2 (ja) * | 2008-02-01 | 2015-04-08 | サノフィ パストゥール リミテッドＳａｎｏｆｉ Ｐａｓｔｅｕｒ Ｌｉｍｉｔｅｄ | 診断的アッセイ |
| SI2268618T1 (sl) | 2008-03-03 | 2015-09-30 | Novartis Ag | Spojine in sestavki kot modulatorji aktivnosti TLR |
| JP5668049B2 (ja) | 2009-03-24 | 2015-02-12 | ノバルティス アーゲー | 髄膜炎菌ｈ因子結合タンパク質および肺炎球菌糖結合体の組み合わせ |
| EP2440245B1 (en) | 2009-06-10 | 2017-12-06 | GlaxoSmithKline Biologicals SA | Benzonaphthyridine-containing vaccines |
| BR112012004806B8 (pt) | 2009-09-02 | 2022-10-04 | Novartis Ag | composições imunogênicas que incluem moduladores da atividade de tlr, método para aumento da eficácia da referida composição e uso |
| TWI445708B (zh) | 2009-09-02 | 2014-07-21 | Irm Llc | 作為ｔｌｒ活性調節劑之化合物及組合物 |
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| BR112012018343A2 (pt) * | 2009-12-22 | 2017-06-27 | Sanofi Pasteur Ltd | "composições imunogênicas" |
| GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
| GB201003920D0 (en) * | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
| CA2792938C (en) | 2010-03-23 | 2018-07-31 | Irm Llc | Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc. |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| RU2589256C2 (ru) * | 2010-12-03 | 2016-07-10 | Санофи Пастер Лимитид | Композиции и способы для иммунизации против streptococcus pneumoniae |
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| JP7630603B2 (ja) | 2020-08-10 | 2025-02-17 | インベントプライズ・インコーポレイテッド | 出現血清型２４ｆを含む多価肺炎球菌複合糖質ワクチン |
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2001
- 2001-09-12 CZ CZ2003-756A patent/CZ305324B6/cs not_active IP Right Cessation
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- 2001-09-12 AT AT01984626T patent/ATE516815T1/de active
- 2001-09-12 EP EP10179135A patent/EP2305298A1/en not_active Withdrawn
- 2001-09-12 KR KR1020117026231A patent/KR101268790B1/ko not_active Expired - Fee Related
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