DE69942176D1 - Choline-bindende proteine derivate aus pneumokoken als impfstoff - Google Patents

Choline-bindende proteine derivate aus pneumokoken als impfstoff

Info

Publication number
DE69942176D1
DE69942176D1 DE69942176T DE69942176T DE69942176D1 DE 69942176 D1 DE69942176 D1 DE 69942176D1 DE 69942176 T DE69942176 T DE 69942176T DE 69942176 T DE69942176 T DE 69942176T DE 69942176 D1 DE69942176 D1 DE 69942176D1
Authority
DE
Germany
Prior art keywords
vaccine
choline
pneumocokes
binding protein
protein derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69942176T
Other languages
English (en)
Inventor
Theresa M Wizemann
Scott Koenig
Leslie S Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedImmune LLC
Original Assignee
MedImmune LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MedImmune LLC filed Critical MedImmune LLC
Application granted granted Critical
Publication of DE69942176D1 publication Critical patent/DE69942176D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
DE69942176T 1998-04-07 1999-04-06 Choline-bindende proteine derivate aus pneumokoken als impfstoff Expired - Lifetime DE69942176D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US8574398P 1998-05-15 1998-05-15
PCT/US1999/007680 WO1999051266A2 (en) 1998-04-07 1999-04-06 Derivatives of pneumococcal choline binding proteins for vaccines

Publications (1)

Publication Number Publication Date
DE69942176D1 true DE69942176D1 (de) 2010-05-06

Family

ID=26764078

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69942176T Expired - Lifetime DE69942176D1 (de) 1998-04-07 1999-04-06 Choline-bindende proteine derivate aus pneumokoken als impfstoff

Country Status (16)

Country Link
US (3) US6503511B1 (de)
EP (1) EP1067962B1 (de)
JP (1) JP2002510649A (de)
KR (2) KR100794394B1 (de)
CN (1) CN1200731C (de)
AT (1) ATE461709T1 (de)
AU (1) AU766455C (de)
BR (1) BR9909483A (de)
CA (1) CA2325340A1 (de)
DE (1) DE69942176D1 (de)
ES (1) ES2343492T3 (de)
HU (1) HUP0102617A3 (de)
IL (2) IL138798A0 (de)
NO (1) NO20004972L (de)
NZ (2) NZ530277A (de)
WO (1) WO1999051266A2 (de)

Families Citing this family (35)

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US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
KR100794394B1 (ko) * 1998-04-07 2008-01-15 메디뮨 인코포레이티드 백신용 폐렴 구균의 콜린 결합성 단백질의 유도체
US6858706B2 (en) 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
CN1191851C (zh) * 1998-04-07 2005-03-09 圣朱德儿童研究医院 包含胆碱结合蛋白an－末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
EP1162999B1 (de) 1999-03-19 2006-11-29 Glaxosmithkline Biologicals S.A. Impstoff gegen Streptococcus pneumoniae
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
AU2001287645A1 (en) * 2000-07-20 2002-02-05 Hansa Medical Ab Fh-binding protein of streptococcus pneumiae
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
US6674504B1 (en) 2000-09-29 2004-01-06 Kent Optronics, Inc. Single layer multi-state ultra-fast cholesteric liquid crystal device and the fabrication methods thereof
PL375408A1 (en) 2002-08-02 2005-11-28 Glaxosmithkline Biologicals S.A. Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria
JP2006504801A (ja) 2002-11-01 2006-02-09 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 乾燥方法
ES2346314T3 (es) 2003-10-02 2010-10-14 Glaxosmithkline Biolog Sa Antigenos de b. pertussis y uso de los mismos en vacunacion.
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
US8052971B2 (en) * 2005-11-21 2011-11-08 MG Biologics Oral use of specific antibodies for intestinal health
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
DK3017827T3 (en) 2005-12-22 2019-02-18 Glaxosmithkline Biologicals Sa Pneumococcal polysaccharide conjugate VACCINE
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
KR20080096775A (ko) 2006-01-17 2008-11-03 아르네 포르스그렌 표면 노출된 헤모필루스 인플루엔자 단백질 （단백질 Ｅ ―ｐＥ）
WO2008039838A2 (en) 2006-09-27 2008-04-03 St. Jude Children's Research Hospital Synthetic streptococcus pneumoniae vaccine
WO2009000826A1 (en) 2007-06-26 2008-12-31 Glaxosmithkline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
JP5056490B2 (ja) * 2008-03-10 2012-10-24 富士通株式会社 歪み補償係数更新装置および歪み補償増幅器
KR20110009157A (ko) 2008-04-16 2011-01-27 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
CN102869378A (zh) 2010-03-10 2013-01-09 葛兰素史密丝克莱恩生物有限公司 免疫原性组合物
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
CA2832115C (en) 2011-04-08 2021-03-02 Tufts Medical Center, Inc. Pepducin design and use
SG194733A1 (en) 2011-05-17 2013-12-30 Glaxosmithkline Biolog Sa Vaccine against streptococcus pneumoniae
JP2014000016A (ja) * 2012-06-15 2014-01-09 National Agriculture & Food Research Organization 豚丹毒菌の新規な抗原タンパク質、その遺伝子、及び組換えベクターとその利用
GB201318170D0 (en) * 2013-10-14 2013-11-27 Univ Edinburgh Proteins with Diagnostic and Therapeutic Uses
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CA3005029A1 (en) 2015-11-13 2017-05-18 Oasis Pharmaceuticals, LLC Protease-activated receptor-2 modulators
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
MX2019014829A (es) 2017-06-10 2020-08-17 Inventprise Llc Vacunas de conjugado multivalente con polisacáridos de conjugado bivalente o multivalente que proporcionan inmunogenicidad y avidez mejoradas.
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
US6042838A (en) * 1991-02-15 2000-03-28 Uab Research Foundation immunogenic compositions for mucosal administration of pneumococcal surface protein A (PspA)
US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US6027734A (en) * 1991-02-15 2000-02-22 Uab Research Foundation Mucosal administration of pneumococcal antigens
US6231870B1 (en) * 1995-06-02 2001-05-15 Uab Research Foundation Oral administration of pneumoccal antigens
US6232116B1 (en) * 1991-02-15 2001-05-15 University Of Alabama At Birmingham Research Foundation Oral administration of pneumococcal antigens
US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US6245335B1 (en) * 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
CA2253252A1 (en) * 1996-05-01 1997-11-06 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
AU6909098A (en) * 1996-10-31 1998-05-22 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
BR9712900A (pt) * 1996-11-06 2000-11-28 Univ California Enzima liberadora de receptor de fator de necrose de tumor isolado, composições que compreendem a enzima e métodos de utilização da mesma
WO1998021337A2 (en) * 1996-11-12 1998-05-22 Regents Of The University Of Minnesota C3 BINDING PROTEIN OF $i(STREPTOCOCCUS PNEUMONIAE)
DE19708537A1 (de) 1997-03-03 1998-09-10 Biotechnolog Forschung Gmbh Neues Oberflächenprotein (SpsA-Protein) von Streptococcus pneumoniae etc.
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
KR100794394B1 (ko) * 1998-04-07 2008-01-15 메디뮨 인코포레이티드 백신용 폐렴 구균의 콜린 결합성 단백질의 유도체
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
US6936252B2 (en) * 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
WO2000037105A2 (en) * 1998-12-21 2000-06-29 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
CA2407455A1 (en) * 2000-04-27 2001-11-01 Medimmune, Inc. Immunogenic pneumococcal protein and vaccine compositions thereof
EP2921924B1 (de) * 2014-03-21 2018-09-19 Asco Numatics GmbH Vorrichtung zur Bereitstellung eines Fluids mit geregeltem Ausgangsdruck
US9741151B2 (en) * 2015-04-14 2017-08-22 International Business Machines Corporation Mobile interactive comparison chart

Also Published As

Publication number Publication date
KR20010034752A (ko) 2001-04-25
CA2325340A1 (en) 1999-10-14
AU766455C (en) 2004-12-02
US6503511B1 (en) 2003-01-07
US20050142145A1 (en) 2005-06-30
EP1067962A2 (de) 2001-01-17
WO1999051266A2 (en) 1999-10-14
IL138798A0 (en) 2001-10-31
AU3386999A (en) 1999-10-25
ES2343492T3 (es) 2010-08-02
CN1200731C (zh) 2005-05-11
US20030138447A1 (en) 2003-07-24
US7435421B2 (en) 2008-10-14
NO20004972L (no) 2000-12-05
NZ507717A (en) 2004-02-27
HUP0102617A2 (hu) 2001-11-28
JP2002510649A (ja) 2002-04-09
CN1315870A (zh) 2001-10-03
IL138798A (en) 2008-11-03
NO20004972D0 (no) 2000-10-03
HUP0102617A3 (en) 2006-04-28
KR100794394B1 (ko) 2008-01-15
ATE461709T1 (de) 2010-04-15
AU766455B2 (en) 2003-10-16
KR20060126844A (ko) 2006-12-08
EP1067962B1 (de) 2010-03-24
NZ530277A (en) 2005-08-26
BR9909483A (pt) 2001-10-09
US6863893B2 (en) 2005-03-08
WO1999051266A3 (en) 1999-12-09

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