DE69833876D1 - Zusammensetzungen und methoden zur zielgerichteten abgabe von biologisch aktivenfaktoren - Google Patents
Zusammensetzungen und methoden zur zielgerichteten abgabe von biologisch aktivenfaktorenInfo
- Publication number
- DE69833876D1 DE69833876D1 DE69833876T DE69833876T DE69833876D1 DE 69833876 D1 DE69833876 D1 DE 69833876D1 DE 69833876 T DE69833876 T DE 69833876T DE 69833876 T DE69833876 T DE 69833876T DE 69833876 D1 DE69833876 D1 DE 69833876D1
- Authority
- DE
- Germany
- Prior art keywords
- compositions
- methods
- targeted delivery
- active factors
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/966,940 US6274552B1 (en) | 1993-03-18 | 1997-11-10 | Composition and method for delivery of biologically-active factors |
US7581198P | 1998-02-24 | 1998-02-24 | |
US75811P | 1998-02-24 | ||
US8669698P | 1998-05-26 | 1998-05-26 | |
US86696P | 1998-05-26 | ||
US10745598P | 1998-11-06 | 1998-11-06 | |
US107455P | 1998-11-06 | ||
PCT/US1998/023931 WO1999024077A2 (en) | 1997-11-10 | 1998-11-10 | Compositions and methods for targeted delivery of biologically-active factors |
US966940 | 2001-09-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69833876D1 true DE69833876D1 (de) | 2006-05-11 |
DE69833876T2 DE69833876T2 (de) | 2007-05-24 |
Family
ID=27491221
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69833876T Expired - Lifetime DE69833876T2 (de) | 1997-11-10 | 1998-11-10 | Zusammensetzungen und verfahren für die gezielte abgabe von faktoren |
Country Status (9)
Country | Link |
---|---|
US (1) | US20090035265A1 (de) |
EP (1) | EP1044022B1 (de) |
JP (1) | JP4620243B2 (de) |
AT (1) | ATE320270T1 (de) |
AU (1) | AU760035B2 (de) |
CA (1) | CA2309604C (de) |
DE (1) | DE69833876T2 (de) |
NZ (1) | NZ504291A (de) |
WO (1) | WO1999024077A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010055581A1 (en) | 1994-03-18 | 2001-12-27 | Lawrence Tamarkin | Composition and method for delivery of biologically-active factors |
US6407218B1 (en) | 1997-11-10 | 2002-06-18 | Cytimmune Sciences, Inc. | Method and compositions for enhancing immune response and for the production of in vitro mabs |
AU757357B2 (en) * | 1997-11-10 | 2003-02-20 | Cytimmune Sciences, Inc. | Methods and compositions for enhancing immune response and for the production of in vitro mabs |
JP2009286808A (ja) * | 1997-11-10 | 2009-12-10 | Cytimmune Sciences Inc | 生物学的に活性な因子の標的化された送達のための組成物および方法 |
US7229841B2 (en) * | 2001-04-30 | 2007-06-12 | Cytimmune Sciences, Inc. | Colloidal metal compositions and methods |
CA2448607C (en) * | 2001-04-30 | 2013-01-22 | Cytimmune Sciences, Inc. | Colloidal metal compositions and methods |
EP1694301A4 (de) * | 2003-12-02 | 2009-11-18 | Cytimmune Sciences Inc | Verfahren und zusammensetzungen zur herstellung von monoklonalen antikörpern |
GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
US8877156B2 (en) | 2007-06-26 | 2014-11-04 | New York University | Contrast agents anchored by thiols on nanoparticles |
EP2200932A4 (de) * | 2007-09-21 | 2014-09-10 | Cytimmune Sciences Inc | Nanotherapeutische kolloidale metallzusammensetzungen und verfahren |
WO2009062151A1 (en) | 2007-11-08 | 2009-05-14 | Cytimmune Sciences, Inc. | Compositions and methods for generating antibodies |
CN102088991A (zh) | 2008-05-13 | 2011-06-08 | 堪萨斯大学 | 金属提取肽标签和相关方法 |
US9187735B2 (en) | 2012-06-01 | 2015-11-17 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
US10064940B2 (en) | 2013-12-11 | 2018-09-04 | Siva Therapeutics Inc. | Multifunctional radiation delivery apparatus and method |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963354A (en) * | 1987-01-21 | 1990-10-16 | Genentech, Inc. | Use of tumor necrosis factor (TNF) as an adjuvant |
US5047523A (en) * | 1988-08-02 | 1991-09-10 | Ortho Diagnostic Systems Inc. | Nucleic acid probe for detection of neisseria gonorrhoea |
US5248772A (en) * | 1992-01-29 | 1993-09-28 | Coulter Corporation | Formation of colloidal metal dispersions using aminodextrans as reductants and protective agents |
AU6414994A (en) * | 1993-03-18 | 1994-10-11 | Cytimmune Sciences, Inc. | Composition and method for reducing toxicity of biologically-active factors |
JPH07227299A (ja) * | 1994-02-14 | 1995-08-29 | Kyoto Daiichi Kagaku:Kk | Dnaの特定塩基配列の検出方法及びその装置 |
US5521289A (en) * | 1994-07-29 | 1996-05-28 | Nanoprobes, Inc. | Small organometallic probes |
US5686578A (en) * | 1994-08-05 | 1997-11-11 | Immunomedics, Inc. | Polyspecific immunoconjugates and antibody composites for targeting the multidrug resistant phenotype |
CA2223261C (en) * | 1995-06-07 | 2010-05-11 | Immunomedics, Inc. | Improved delivery of diagnostic and therapeutic agents to a target site |
JPH10511989A (ja) * | 1996-04-10 | 1998-11-17 | サングスタット メディカル コーポレイション | 特異的結合ペア構成要素の細胞調節性複合体 |
DE19622628A1 (de) * | 1996-06-05 | 1997-12-11 | Boehringer Mannheim Gmbh | Stabilisierung von Metallkonjugaten |
US6294378B1 (en) * | 1996-07-26 | 2001-09-25 | Sloan-Kettering Institute For Cancer Research | Method and reagents for genetic immunization |
ATE302217T1 (de) * | 1997-05-02 | 2005-09-15 | Us Gov Health & Human Serv | Immuntoxine, die ein onc protein enthalten, gegen bösartige zellen |
DE19726186A1 (de) * | 1997-06-20 | 1998-12-24 | Boehringer Ingelheim Int | Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen |
JP4833862B2 (ja) * | 2004-01-28 | 2011-12-07 | サイトイミューン サイエンシズ インコーポレイテッド | 官能化コロイド金属組成物および方法 |
US20060185027A1 (en) * | 2004-12-23 | 2006-08-17 | David Bartel | Systems and methods for identifying miRNA targets and for altering miRNA and target expression |
-
1998
- 1998-11-10 AU AU13940/99A patent/AU760035B2/en not_active Ceased
- 1998-11-10 DE DE69833876T patent/DE69833876T2/de not_active Expired - Lifetime
- 1998-11-10 AT AT98957757T patent/ATE320270T1/de active
- 1998-11-10 NZ NZ504291A patent/NZ504291A/xx not_active IP Right Cessation
- 1998-11-10 JP JP2000520162A patent/JP4620243B2/ja not_active Expired - Fee Related
- 1998-11-10 EP EP98957757A patent/EP1044022B1/de not_active Expired - Lifetime
- 1998-11-10 WO PCT/US1998/023931 patent/WO1999024077A2/en active IP Right Grant
- 1998-11-10 CA CA002309604A patent/CA2309604C/en not_active Expired - Fee Related
-
2008
- 2008-10-13 US US12/250,126 patent/US20090035265A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1044022A2 (de) | 2000-10-18 |
CA2309604C (en) | 2010-01-12 |
US20090035265A1 (en) | 2009-02-05 |
ATE320270T1 (de) | 2006-04-15 |
AU760035B2 (en) | 2003-05-08 |
AU1394099A (en) | 1999-05-31 |
EP1044022B1 (de) | 2006-03-15 |
DE69833876T2 (de) | 2007-05-24 |
WO1999024077A3 (en) | 1999-10-07 |
JP2001522818A (ja) | 2001-11-20 |
JP4620243B2 (ja) | 2011-01-26 |
NZ504291A (en) | 2002-10-25 |
CA2309604A1 (en) | 1999-05-20 |
WO1999024077A2 (en) | 1999-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |