CY1108761T1 - Απενεργοποιημενες κυτοκινες για ανοσοποιηση - Google Patents
Απενεργοποιημενες κυτοκινες για ανοσοποιησηInfo
- Publication number
- CY1108761T1 CY1108761T1 CY20091100121T CY091100121T CY1108761T1 CY 1108761 T1 CY1108761 T1 CY 1108761T1 CY 20091100121 T CY20091100121 T CY 20091100121T CY 091100121 T CY091100121 T CY 091100121T CY 1108761 T1 CY1108761 T1 CY 1108761T1
- Authority
- CY
- Cyprus
- Prior art keywords
- disabilized
- immunization
- cats
- carboxymethylated
- regulatory protein
- Prior art date
Links
- 230000003053 immunization Effects 0.000 title 1
- 238000002649 immunization Methods 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 3
- 102000006992 Interferon-alpha Human genes 0.000 abstract 2
- 108010047761 Interferon-alpha Proteins 0.000 abstract 2
- 108010052104 Viral Regulatory and Accessory Proteins Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5412—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5437—IL-13
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Η εφεύρεση αφορά παράγωγο ιικής ρυθμιστικής πρωτεΐνης ή ένα θραύσμα ιικής ρυθμιστικής πρωτεΐνης ή άλφα ιντερφερόνη ή θραύσμα άλφα ιντερφερόνης που είναι καρβοξυμεθυλιωμένο, μέθοδο παρασκευής, χρήση του προκύπτοντος προϊόντος σε μια μέθοδο θεραπείας για το ανθρώπινο ή ζωικό σώμα, φαρμακευτική σύνθεση και εμβόλιο που περιέχει ως δραστικό συστατικό τουλάχιστον μια από τις καρβοξυμεθυλιωμένες πρωτεΐνες ή θραύσματα.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9905258A FR2792639B1 (fr) | 1999-04-26 | 1999-04-26 | Nouveaux immunogenes anti-vih (toxoides), nouveaux procedes de preparation et application a la prevention et au traitement du sida |
| EP00922696A EP1173481B1 (fr) | 1999-04-26 | 2000-04-20 | Cytokines inactives pour l'immunisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108761T1 true CY1108761T1 (el) | 2014-04-09 |
Family
ID=9544858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100121T CY1108761T1 (el) | 1999-04-26 | 2009-02-03 | Απενεργοποιημενες κυτοκινες για ανοσοποιηση |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6878370B1 (el) |
| EP (1) | EP1173481B1 (el) |
| AT (1) | ATE415419T1 (el) |
| AU (1) | AU4300700A (el) |
| CY (1) | CY1108761T1 (el) |
| DE (1) | DE60040910D1 (el) |
| DK (1) | DK1173481T3 (el) |
| ES (1) | ES2316364T3 (el) |
| FR (1) | FR2792639B1 (el) |
| PT (1) | PT1173481E (el) |
| WO (1) | WO2000064937A1 (el) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2844514B1 (fr) * | 2002-09-16 | 2007-10-19 | Neovacs | Produit immunogene stable comprenant des heterocomplexes antigeniques, compositions les contenant et procede de preparation |
| EP4079328A1 (en) | 2015-05-05 | 2022-10-26 | Rubicon Biotechnology LLC | Cancer immunotherapeutic |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4414147A (en) * | 1981-04-17 | 1983-11-08 | Massachusetts Institute Of Technology | Methods of decreasing the hydrophobicity of fibroblast and other interferons |
| FR2677654B1 (fr) * | 1991-06-17 | 1995-11-17 | Pasteur Merieux Serums Vacc | Composes a effet immunogene anti-cytokine, a effet immunogene anticytostatique ou a effet vaccinal anti-infection a hiv. |
| CA2158475C (en) * | 1993-03-18 | 2009-06-02 | Lawrence Tamarkin | Composition and method for reducing toxicity of biologically-active factors |
| FR2773156B1 (fr) * | 1997-12-26 | 2000-03-31 | Biovacs Inc | Nouveaux immunogenes anti-retroviraux (toxoides), nouveaux procedes de preparation et application a la prevention et au traitement du sida |
-
1999
- 1999-04-26 FR FR9905258A patent/FR2792639B1/fr not_active Expired - Fee Related
-
2000
- 2000-04-20 AU AU43007/00A patent/AU4300700A/en not_active Abandoned
- 2000-04-20 PT PT00922696T patent/PT1173481E/pt unknown
- 2000-04-20 DK DK00922696T patent/DK1173481T3/da active
- 2000-04-20 EP EP00922696A patent/EP1173481B1/fr not_active Expired - Lifetime
- 2000-04-20 ES ES00922696T patent/ES2316364T3/es not_active Expired - Lifetime
- 2000-04-20 AT AT00922696T patent/ATE415419T1/de active
- 2000-04-20 WO PCT/FR2000/001043 patent/WO2000064937A1/fr active Application Filing
- 2000-04-20 DE DE60040910T patent/DE60040910D1/de not_active Expired - Lifetime
- 2000-04-20 US US09/959,461 patent/US6878370B1/en not_active Expired - Lifetime
-
2005
- 2005-03-21 US US11/084,175 patent/US7208148B2/en not_active Expired - Lifetime
-
2009
- 2009-02-03 CY CY20091100121T patent/CY1108761T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1173481A1 (fr) | 2002-01-23 |
| EP1173481B1 (fr) | 2008-11-26 |
| AU4300700A (en) | 2000-11-10 |
| DK1173481T3 (da) | 2009-03-02 |
| US20050180950A1 (en) | 2005-08-18 |
| ES2316364T3 (es) | 2009-04-16 |
| ATE415419T1 (de) | 2008-12-15 |
| WO2000064937A1 (fr) | 2000-11-02 |
| US7208148B2 (en) | 2007-04-24 |
| DE60040910D1 (de) | 2009-01-08 |
| FR2792639A1 (fr) | 2000-10-27 |
| PT1173481E (pt) | 2009-01-29 |
| FR2792639B1 (fr) | 2003-06-06 |
| US6878370B1 (en) | 2005-04-12 |
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