JP2011529093A - 知覚過敏歯の処置方法 - Google Patents
知覚過敏歯の処置方法 Download PDFInfo
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- JP2011529093A JP2011529093A JP2011520354A JP2011520354A JP2011529093A JP 2011529093 A JP2011529093 A JP 2011529093A JP 2011520354 A JP2011520354 A JP 2011520354A JP 2011520354 A JP2011520354 A JP 2011520354A JP 2011529093 A JP2011529093 A JP 2011529093A
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- Prior art keywords
- isomalt
- polyol
- maltitol
- xylitol
- tooth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000010972 statistical evaluation Methods 0.000 description 1
- 229940013618 stevioside Drugs 0.000 description 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 235000019202 steviosides Nutrition 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 229910001637 strontium fluoride Inorganic materials 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 235000019408 sucralose Nutrition 0.000 description 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000000892 thaumatin Substances 0.000 description 1
- 235000010436 thaumatin Nutrition 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Confectionery (AREA)
- Jellies, Jams, And Syrups (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
【選択図】なし
Description
コーティングシロップのレシピ:
バッチサイズ:7.5 kgチューインガム中身
イソマルトGS 6500 g
水 3364 g
ゼラチン 26 g
アスパルテーム 5 g
アセサルファームK 5 g
二酸化チタン 100 g
合計 10000 g
ドライチャージ(Drycharge):
イソマルトST/PF:フェーズ1:1 x 100 g;フェーズ2:5 x 80 g
香味料:フェーズ3でH&R オプタミント(Optamint):2 x 25 g、光沢剤(Glazing agent):艶出しワックス(polishing wax)(Fa. Kahl)、シロップ温度:65℃
シロップの調製:
まずイソマルトGSを水に溶解し、他の成分をシロップに添加する。調製後、シロップを65℃に保つ。
基本のチューインガムコンパウンドを、ニーダー(kneader)に移す前に、加熱キャビネット中で50℃〜55℃の温度に加熱する。その後、基本のチューインガムコンパウンドを1〜2分間練る。練っている間に、甘味料混合物の最初の半分、その後グリセロールを添加し、そして最後に香味料、メントール及び甘味料を添加する。均一になるまで混合物を練る(最終温度約45℃)。塊をニーダーから取り出し、約1 kg重量の部分に分ける。中間の保存のため、分割したチューインガムの塊をタルカムを撒いた基板上に約15〜20分間置き、適切な押出機で押し出し、従来の方法でさらに加工する。
冷たいものに対する知覚過敏症を有する50人の被験体がこの実験に参加した。56日目まで8週間(以下の表を参照)、1日に3回(午前中、正午及び夜に)、実施例1のイソマルトを含有するチューインガムを10分間噛んだ。
Claims (13)
- 食品、化粧品又は医薬品を、歯を減感させるのに有効な量のポリオールと混合することを含む、食品、化粧品又は医薬品に歯減感効果を付与する方法。
- ポリオールがイソマルト、マルチトール又はキシリトールである、請求項1に記載の方法。
- ポリオールがイソマルトである、請求項1に記載の方法。
- イソマルトが、1,1-GPM(1-O-α-D-グルコピラノシル-D-マンニトール)及び1,6-GPS(6-O-α-D-グルコピラノシル-D-ソルビトール)の等モル混合物である、請求項3に記載の方法。
- イソマルトがイソマルト変異体である、請求項3に記載の方法。
- 食品が、チューインガム、ハードキャラメル、ソフトキャラメル、タフィー、トローチ(pastille)、錠剤、ガム、ゼリー、マシュマロ、ドロップ(lozenge)、ファッジ及びフォンダンからなる群より選択される、請求項1に記載の方法。
- 有効量のポリオールを動物又はヒトに投与することを含む、処置が必要な動物又はヒトにおける知覚過敏歯の予防的又は治療的処置方法。
- ポリオールがイソマルト、マルチトール又はキシリトールである、請求項7に記載の方法。
- ポリオールがイソマルトである、請求項7に記載の方法。
- 歯を減感させるために歯の表面に有効量のポリオールを投与することを含む、知覚過敏歯の減感方法。
- ポリオールがイソマルト、マルチトール又はキシリトールである、請求項10に記載の方法。
- ポリオールがイソマルトである、請求項10に記載の方法。
- ポリオールが食品、化粧品又は医薬品中に有効量で含まれる、請求項7又は10に記載の方法。
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US12/180,837 | 2008-07-28 | ||
US12/180,837 US7919107B2 (en) | 2008-07-28 | 2008-07-28 | Method for treating hypersensitive teeth |
PCT/EP2009/005169 WO2010012386A2 (en) | 2008-07-28 | 2009-07-16 | Method for treating hypersensitive teeth |
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JP2014250633A Division JP5985597B2 (ja) | 2008-07-28 | 2014-12-11 | 知覚過敏歯の処置方法 |
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JP2014250633A Active JP5985597B2 (ja) | 2008-07-28 | 2014-12-11 | 知覚過敏歯の処置方法 |
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US (1) | US7919107B2 (ja) |
EP (1) | EP2317867B1 (ja) |
JP (2) | JP6045791B2 (ja) |
CN (1) | CN102164503B (ja) |
BR (1) | BRPI0916818A2 (ja) |
EA (1) | EA021680B1 (ja) |
ES (1) | ES2657237T3 (ja) |
PL (1) | PL2317867T3 (ja) |
WO (1) | WO2010012386A2 (ja) |
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JP2014014318A (ja) * | 2012-07-09 | 2014-01-30 | Suntory Holdings Ltd | ビールテイスト飲料の中間製品である濾過前液の濾過性の予測方法 |
JP2017510609A (ja) * | 2014-04-10 | 2017-04-13 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | 口腔ケア組成物 |
JPWO2016031461A1 (ja) * | 2014-08-29 | 2017-06-08 | 日油株式会社 | 象牙質知覚過敏症緩和用口腔組成物 |
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US20110117031A1 (en) * | 2008-07-28 | 2011-05-19 | Stephan Hausmanns | Method for treating hypersensitive teeth |
GB201105408D0 (en) * | 2011-03-30 | 2011-05-11 | Glaxo Group Ltd | Composition |
TW201519180A (zh) * | 2013-10-09 | 2015-05-16 | Colgate Palmolive Co | 牙齒解剖模型及展示方法 |
ES2865698T3 (es) * | 2013-10-31 | 2021-10-15 | Suedzucker Ag | Gomas de mascar mejoradas y métodos para su preparación |
US20240099989A1 (en) * | 2021-02-05 | 2024-03-28 | Kinki University | Agent for preventing or improving peripheral neuropathy |
RU2758512C1 (ru) * | 2021-03-05 | 2021-10-29 | Федеральное государственное бюджетное образовательное учреждение высшего образования «Воронежский государственный университет инженерных технологий» (ФГБОУ ВО «ВГУИТ») | Способ производства зефира без добавления сахара |
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- 2009-07-16 JP JP2011520354A patent/JP6045791B2/ja active Active
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- 2009-07-16 BR BRPI0916818-4A patent/BRPI0916818A2/pt not_active Application Discontinuation
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CN102164503A (zh) | 2011-08-24 |
CN102164503B (zh) | 2015-04-01 |
ES2657237T3 (es) | 2018-03-02 |
US20100021508A1 (en) | 2010-01-28 |
US7919107B2 (en) | 2011-04-05 |
PL2317867T3 (pl) | 2018-05-30 |
BRPI0916818A2 (pt) | 2015-07-28 |
JP6045791B2 (ja) | 2016-12-14 |
JP2015083586A (ja) | 2015-04-30 |
JP5985597B2 (ja) | 2016-09-06 |
WO2010012386A3 (en) | 2010-04-08 |
EP2317867B1 (en) | 2017-11-15 |
EA021680B1 (ru) | 2015-08-31 |
EA201170267A1 (ru) | 2011-08-30 |
EP2317867A2 (en) | 2011-05-11 |
WO2010012386A2 (en) | 2010-02-04 |
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