JP2011528656A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011528656A5 JP2011528656A5 JP2011518816A JP2011518816A JP2011528656A5 JP 2011528656 A5 JP2011528656 A5 JP 2011528656A5 JP 2011518816 A JP2011518816 A JP 2011518816A JP 2011518816 A JP2011518816 A JP 2011518816A JP 2011528656 A5 JP2011528656 A5 JP 2011528656A5
- Authority
- JP
- Japan
- Prior art keywords
- drug delivery
- delivery system
- administered
- eye
- amd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012377 drug delivery Methods 0.000 claims 16
- 208000011325 dry age related macular degeneration Diseases 0.000 claims 7
- 229960000397 bevacizumab Drugs 0.000 claims 5
- 239000004037 angiogenesis inhibitor Substances 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 208000000208 Wet Macular Degeneration Diseases 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 108010041308 Endothelial Growth Factors Proteins 0.000 claims 1
- 208000007135 Retinal Neovascularization Diseases 0.000 claims 1
- 206010064930 age-related macular degeneration Diseases 0.000 claims 1
- 230000002137 anti-vascular effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229960003876 ranibizumab Drugs 0.000 claims 1
- 210000003786 sclera Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/176,238 | 2008-07-18 | ||
| US12/176,238 US8821870B2 (en) | 2008-07-18 | 2008-07-18 | Method for treating atrophic age related macular degeneration |
| PCT/US2009/050373 WO2010009034A2 (en) | 2008-07-18 | 2009-07-13 | Method for treating atrophic age related macular degeneration |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014169846A Division JP6009511B2 (ja) | 2008-07-18 | 2014-08-22 | 萎縮性加齢性黄斑変性の処置方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011528656A JP2011528656A (ja) | 2011-11-24 |
| JP2011528656A5 true JP2011528656A5 (enExample) | 2012-08-16 |
Family
ID=41530477
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011518816A Pending JP2011528656A (ja) | 2008-07-18 | 2009-07-13 | 萎縮性加齢性黄斑変性の処置方法 |
| JP2014169846A Expired - Fee Related JP6009511B2 (ja) | 2008-07-18 | 2014-08-22 | 萎縮性加齢性黄斑変性の処置方法 |
| JP2016124732A Expired - Fee Related JP6132964B2 (ja) | 2008-07-18 | 2016-06-23 | 萎縮性加齢性黄斑変性の処置方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014169846A Expired - Fee Related JP6009511B2 (ja) | 2008-07-18 | 2014-08-22 | 萎縮性加齢性黄斑変性の処置方法 |
| JP2016124732A Expired - Fee Related JP6132964B2 (ja) | 2008-07-18 | 2016-06-23 | 萎縮性加齢性黄斑変性の処置方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8821870B2 (enExample) |
| EP (4) | EP3524270B1 (enExample) |
| JP (3) | JP2011528656A (enExample) |
| KR (1) | KR20110047196A (enExample) |
| CN (2) | CN102159246A (enExample) |
| AU (1) | AU2009271168B2 (enExample) |
| BR (1) | BRPI0915981A2 (enExample) |
| CA (1) | CA2731270C (enExample) |
| ES (3) | ES2720882T3 (enExample) |
| RU (3) | RU2521338C9 (enExample) |
| WO (1) | WO2010009034A2 (enExample) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090148527A1 (en) * | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| US8039010B2 (en) | 2006-11-03 | 2011-10-18 | Allergan, Inc. | Sustained release intraocular drug delivery systems comprising a water soluble therapeutic agent and a release modifier |
| US8821870B2 (en) * | 2008-07-18 | 2014-09-02 | Allergan, Inc. | Method for treating atrophic age related macular degeneration |
| AU2010208046B2 (en) | 2009-01-29 | 2014-10-02 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| KR20120095371A (ko) * | 2009-10-01 | 2012-08-28 | 에보닉 데구사 코포레이션 | 노화 황반변성 치료용 극미립자 조성물들 및 노화 황반변성 치료방법 |
| ES2468827T3 (es) * | 2010-01-14 | 2014-06-17 | Sanwa Kagaku Kenkyusho Co., Ltd | Producto farmacéutico para prevenir o tratar trastornos acompañados de angiog�nesis ocular y/o permeabilidad vascular ocular elevada |
| US9889088B2 (en) * | 2010-01-21 | 2018-02-13 | Allergan, Inc. | Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect |
| US20130210876A1 (en) * | 2010-01-21 | 2013-08-15 | Allergan, Inc | Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect |
| WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| EP2563359A1 (en) | 2010-04-30 | 2013-03-06 | Allergan, Inc. | Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase |
| CN103209664A (zh) | 2010-08-05 | 2013-07-17 | 弗赛特影像4股份有限公司 | 可植入的治疗装置 |
| AU2011285548B2 (en) | 2010-08-05 | 2014-02-06 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| EP3861969A1 (en) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injector apparatus for drug delivery |
| KR101845107B1 (ko) | 2010-08-17 | 2018-04-03 | 오에이치알 파마서티컬, 인코포레이티드 | 스쿠알라민 안약 제제 |
| JP5996544B2 (ja) | 2010-10-15 | 2016-09-21 | クリアサイド・バイオメディカル・インコーポレーテッドClearside Biomedical Incorporated | 眼球アクセス用装置 |
| WO2012068549A2 (en) | 2010-11-19 | 2012-05-24 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| EP2671589A4 (en) * | 2011-02-02 | 2014-11-19 | Public Univ Corp Nagoya City Univ | MEDICAMENT FOR PREVENTING OR TREATING DISEASES RELATED TO INTRAOCULAR NEOVASCULARIZATION AND / OR INTRAOCULAR VASCULAR HYPERPERMEABILITY |
| US20120276186A1 (en) | 2011-04-29 | 2012-11-01 | Ghebremeskel Alazar N | Sustained release latanoprost implant |
| HRP20192276T1 (hr) * | 2011-06-10 | 2020-05-15 | Ramscor, Inc. | Formulacije s produljenim oslobađanjem za dostavu proteina u oko i postupci njihove pripreme |
| EP2720722A4 (en) | 2011-06-16 | 2014-12-03 | Univ Hong Kong Science & Techn | MOLECULAR WITH SEVERAL VINYL SULPHONES |
| US10398592B2 (en) | 2011-06-28 | 2019-09-03 | Forsight Vision4, Inc. | Diagnostic methods and apparatus |
| RU2014105495A (ru) * | 2011-07-19 | 2015-08-27 | Уилфред ДЖЕФФРИС | Способы диагностики и лечения болезни альцгеймера |
| PT2755600T (pt) | 2011-09-16 | 2021-04-19 | Forsight Vision4 Inc | Aparelhos de troca de fluidos |
| WO2013074840A1 (en) * | 2011-11-15 | 2013-05-23 | Allergan, Inc. | Treatment of dry age related macular degeneration |
| RU2676102C2 (ru) * | 2012-09-27 | 2018-12-26 | Аллерган, Инк. | Биодеградируемые системы доставки лекарственных средств для долговременного высвобождения белков |
| MX373894B (es) | 2012-11-08 | 2020-07-09 | Clearside Biomedical Inc | Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos. |
| CN102988301A (zh) * | 2012-12-26 | 2013-03-27 | 温州医学院 | 一种含贝伐单抗的长效缓释微球的制备方法 |
| US9254409B2 (en) | 2013-03-14 | 2016-02-09 | Icon Health & Fitness, Inc. | Strength training apparatus with flywheel and related methods |
| WO2014152959A1 (en) | 2013-03-14 | 2014-09-25 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| BR112015027762A2 (pt) | 2013-05-03 | 2017-08-29 | Clearside Biomedical Inc | Aparelho e métodos para injeção ocular |
| WO2014197317A1 (en) | 2013-06-03 | 2014-12-11 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
| US20160166701A1 (en) * | 2013-07-05 | 2016-06-16 | Therakine Biodelivery Gmbh | Delivery composition for topical applications and injections and ophthalmic formulations, methods for manufacturing thereof, and methods for delivery of a drug-delivery composition |
| US9782345B2 (en) | 2013-10-17 | 2017-10-10 | Jade Therapeutics, Inc. | Ocular composition and method |
| EP3071181B1 (en) * | 2013-11-18 | 2021-03-24 | Formycon AG | Pharmaceutical composition of an anti-vegf antibody |
| EP3623020B1 (en) | 2013-12-26 | 2024-05-01 | iFIT Inc. | Magnetic resistance mechanism in a cable machine |
| US10426989B2 (en) | 2014-06-09 | 2019-10-01 | Icon Health & Fitness, Inc. | Cable system incorporated into a treadmill |
| EP3157598A4 (en) | 2014-06-20 | 2018-05-16 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| RU2017105844A (ru) | 2014-08-08 | 2018-09-11 | Форсайт Вижн4, Инк. | Стабильные и растворимые составы ингибиторов рецепторных тирозинкиназ и способы их получения |
| USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
| CA2977738A1 (en) * | 2015-02-26 | 2016-09-01 | Feramda Ltd. | Compositions and combinations for the treatment of angiogenesis diseases and disorders |
| ES2584534B1 (es) * | 2015-03-27 | 2017-03-13 | Retinset, S.L. | Formulación tópica oftálmica de bosentan |
| CN108348572B (zh) | 2015-03-31 | 2021-06-29 | 日东制药株式会社 | 含有融合组织穿透肽和抗-vegf制剂的融合蛋白的预防和治疗眼疾的药物组合物 |
| JP6887377B2 (ja) * | 2015-05-29 | 2021-06-16 | 生化学工業株式会社 | グリコサミノグリカン誘導体とケモカイン受容体活性調節材とを含む組成物 |
| US10940360B2 (en) | 2015-08-26 | 2021-03-09 | Icon Health & Fitness, Inc. | Strength exercise mechanisms |
| US10953305B2 (en) | 2015-08-26 | 2021-03-23 | Icon Health & Fitness, Inc. | Strength exercise mechanisms |
| TWI799366B (zh) | 2015-09-15 | 2023-04-21 | 美商建南德克公司 | 胱胺酸結骨架平臺 |
| PE20181363A1 (es) | 2015-09-23 | 2018-08-27 | Genentech Inc | Variantes optimizadas de anticuerpos anti-vegf |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| JP6986758B2 (ja) * | 2016-02-08 | 2021-12-22 | ザ・ジョンズ・ホプキンス・ユニバーシティー | デンドリマー−生体接着性ポリマーヒドロゲルナノ接着剤およびその使用 |
| US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
| CN115951066A (zh) * | 2016-02-29 | 2023-04-11 | 麦恩泰科特有限公司 | 可用于治疗湿性年龄相关性黄斑变性的预测性标志物 |
| JP6664115B2 (ja) * | 2016-03-15 | 2020-03-13 | 原 英彰 | アフリベルセプトによる網膜保護作用 |
| US10441840B2 (en) | 2016-03-18 | 2019-10-15 | Icon Health & Fitness, Inc. | Collapsible strength exercise machine |
| US10293211B2 (en) | 2016-03-18 | 2019-05-21 | Icon Health & Fitness, Inc. | Coordinated weight selection |
| EP3452165A1 (en) | 2016-05-02 | 2019-03-13 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
| US10252109B2 (en) | 2016-05-13 | 2019-04-09 | Icon Health & Fitness, Inc. | Weight platform treadmill |
| US11400080B2 (en) | 2016-05-25 | 2022-08-02 | Santen Pharmaceutical Co., Ltd. | Use of sirolimus to treat exudative age-related macular degeneration with persistent edema |
| IL305537B2 (en) | 2016-08-12 | 2025-02-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a needle for administering a drug |
| US10661114B2 (en) | 2016-11-01 | 2020-05-26 | Icon Health & Fitness, Inc. | Body weight lift mechanism on treadmill |
| US11123411B2 (en) * | 2016-12-08 | 2021-09-21 | Gary E. Borodic | Method of treating macular degeneration using botulinum toxin-based pharmaceuticals |
| RU2661621C2 (ru) * | 2016-12-19 | 2018-07-17 | Александр Николаевич Епихин | Способ пролонгации и усиления терапевтического эффекта действия ингибиторов ангиогенеза при лечении неоваскулярных форм макулярных дегенераций |
| AR111190A1 (es) | 2017-03-22 | 2019-06-12 | Genentech Inc | Composiciones en hidrogel de prodrogas entrecruzadas de ácido hialurónico y métodos relacionados |
| IL270169B2 (en) | 2017-04-27 | 2024-08-01 | Univ Johns Hopkins | Dendrimer preparations for use in angiography |
| US12090294B2 (en) | 2017-05-02 | 2024-09-17 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
| KR102101969B1 (ko) * | 2017-09-06 | 2020-04-22 | (주)인벤티지랩 | 목시덱틴을 포함하는 마이크로 입자 및 이의 제조 방법 |
| US11918657B2 (en) | 2017-11-10 | 2024-03-05 | The Johns Hopkins University | Dendrimer delivery system and methods of use thereof |
| CN111655206B (zh) | 2017-11-21 | 2022-10-14 | 弗赛特影像4股份有限公司 | 用于可扩展端口递送系统的流体交换装置及使用方法 |
| CN108030783A (zh) * | 2017-12-27 | 2018-05-15 | 广东众生药业股份有限公司 | 乐伐替尼在制备防治黄斑变性的药物中的用途 |
| EP3758737A4 (en) | 2018-03-02 | 2022-10-12 | Kodiak Sciences Inc. | IL-6 ANTIBODIES AND FUSION CONSTRUCTS AND CONJUGATES THEREOF |
| AU2019256289A1 (en) * | 2018-04-17 | 2020-11-12 | Outlook Therapeutics, Inc. | Buffered formulations of bevacizumab for use of treating diseases |
| KR102192768B1 (ko) * | 2018-12-07 | 2020-12-18 | 전북대학교산학협력단 | 식나무 추출물을 포함하는 황반변성의 예방 또는 치료용 약학적 조성물 |
| DE102019112917B4 (de) * | 2019-05-16 | 2021-07-22 | Carl Zeiss Meditec Ag | Ophthalmologisches Implantat zur Verwendung bei der Behandlung einer Augenkrankheit und Implantationswerkzeug mit einem solchen ophthalmologischen Implantat |
| CN109966243A (zh) * | 2019-05-17 | 2019-07-05 | 上海第二工业大学 | 一种用于眼底黄斑治疗的释药型凝胶及其制备方法 |
| EP3886946A1 (en) | 2019-06-05 | 2021-10-06 | Regeneron Pharmaceuticals, Inc. | Devices and methods for precision dose delivery |
| AU2020302924A1 (en) | 2019-06-27 | 2022-02-17 | Layerbio, Inc. | Ocular device delivery methods and systems |
| CA3144986A1 (en) * | 2019-06-27 | 2020-12-30 | University Of Florida Research Foundation, Incorporated | Enhancing aav-mediated transduction of ocular tissues with hyaluronic acid |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| PT3861985T (pt) | 2020-02-06 | 2023-08-03 | Ocular Therapeutix Inc | Composições e métodos para tratar doenças oculares |
| PT3884929T (pt) | 2020-03-25 | 2023-08-09 | Ocular Therapeutix Inc | Implante ocular contendo um inibidor da tirosina cinase |
| WO2021262916A1 (en) * | 2020-06-26 | 2021-12-30 | Purdue Research Foundation | Pharmaceutical formulations of griseofulvin for long-term ocular delivery |
| US20240058308A1 (en) * | 2021-01-12 | 2024-02-22 | The Regents Of The University Of Michigan | Treatment and prevention of dry macular degeneration |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
| PE20260040A1 (es) | 2023-04-11 | 2026-01-09 | Ocular Therapeutix Inc | Implante ocular que contiene un inhibidor de la tirosina cinasa |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2446405A (en) | 1945-10-31 | 1948-08-03 | Hazeltine Research Inc | Tunable ultra high frequency resonator system |
| US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
| KR0185215B1 (ko) | 1990-11-30 | 1999-05-01 | 요시다 쇼오지 | 서방성 안구삽입용 약제 |
| US5264188A (en) | 1991-01-22 | 1993-11-23 | Phillips Petroleum Company | Multi-stage hydrotreating process and apparatus |
| US5869079A (en) | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
| HK1042052A1 (zh) * | 1999-02-08 | 2002-08-02 | Human Genome Sciences, Inc. | 内皮血管生长因子-2 |
| US7582311B1 (en) * | 1999-10-15 | 2009-09-01 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| JP2003511204A (ja) | 1999-10-21 | 2003-03-25 | アルコン,インコーポレイティド | テノン下薬剤送出 |
| RU2354398C2 (ru) * | 2001-07-13 | 2009-05-10 | Оксиджин, Инк. | Композиции и способы введения средств, связывающих тубулин, для лечения глазных заболеваний |
| US20040229960A1 (en) | 2001-07-13 | 2004-11-18 | David Sherris | Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases |
| CN1301692C (zh) | 2002-09-18 | 2007-02-28 | 阿勒根公司 | 眼植入物导入的器械 |
| NZ540186A (en) * | 2002-10-31 | 2008-03-28 | Celgene Corp | Composition for the treatment of macular degeneration |
| US20050101582A1 (en) * | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
| US20060182783A1 (en) * | 2004-04-30 | 2006-08-17 | Allergan, Inc. | Sustained release intraocular drug delivery systems |
| US20060182781A1 (en) | 2004-04-30 | 2006-08-17 | Allergan, Inc. | Methods for treating ocular conditions with cyclic lipid contraining microparticles |
| US8425929B2 (en) | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
| US20050244469A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Extended therapeutic effect ocular implant treatments |
| US8591885B2 (en) | 2004-04-30 | 2013-11-26 | Allergan, Inc. | Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems |
| US20050244471A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Estradiol derivative and estratopone containing sustained release intraocular implants and related methods |
| US7993634B2 (en) | 2004-04-30 | 2011-08-09 | Allergan, Inc. | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods |
| US20070059336A1 (en) | 2004-04-30 | 2007-03-15 | Allergan, Inc. | Anti-angiogenic sustained release intraocular implants and related methods |
| US20050244463A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular vasculopathies |
| US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
| US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| US7589057B2 (en) | 2004-04-30 | 2009-09-15 | Allergan, Inc. | Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems |
| WO2005110374A1 (en) | 2004-04-30 | 2005-11-24 | Allergan, Inc. | Intraocular drug delivery systems containing a therapeutic component, a cyclodextrin, and a polymeric component |
| WO2006043965A1 (en) * | 2004-10-14 | 2006-04-27 | Allergan, Inc. | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods |
| DK1848431T3 (en) * | 2005-02-09 | 2016-04-18 | Santen Pharmaceutical Co Ltd | LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS |
| US8003124B2 (en) * | 2005-04-08 | 2011-08-23 | Surmodics, Inc. | Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease |
| NZ566774A (en) * | 2005-09-07 | 2011-11-25 | Pfizer | Human monoclonal antibodies to activin receptor-like kinase-1 |
| US8168584B2 (en) * | 2005-10-08 | 2012-05-01 | Potentia Pharmaceuticals, Inc. | Methods of treating age-related macular degeneration by compstatin and analogs thereof |
| ES2616296T3 (es) | 2005-12-02 | 2017-06-12 | (Osi) Eyetech, Inc. | Micropartículas de liberación controlada |
| US20090221684A1 (en) * | 2005-12-22 | 2009-09-03 | Trustees Of Boston University | Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof |
| JP2009524684A (ja) * | 2006-01-26 | 2009-07-02 | アキュセラ, インコーポレイテッド | 眼疾患および障害の治療のための組成物および方法 |
| WO2007128526A2 (en) | 2006-05-04 | 2007-11-15 | Fovea Pharmaceuticals Sa | Combination comprising a vegf inhibitor and a serine protease for treating neovascular diseases |
| EP2056812A1 (en) * | 2006-08-31 | 2009-05-13 | Abraxis BioScience, LLC | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
| US20100111963A1 (en) | 2006-11-10 | 2010-05-06 | Genentech, Inc. | Method for treating age-related macular degeneration |
| KR101450356B1 (ko) * | 2006-11-24 | 2014-10-15 | 에이씨 이뮨 에스.에이. | 알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 n-(메틸)-1h-피라졸-3-아민, n-(메틸)-피리딘-2-아민 및 n-(메틸)-티아졸-2-아민 유도체 |
| US20080125377A1 (en) * | 2006-11-28 | 2008-05-29 | Bartels Stephen P | Delivery system for antiangiogenic and antiinflammatory pharmaceuticals and method of use |
| US8969415B2 (en) | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
| US11078262B2 (en) | 2007-04-30 | 2021-08-03 | Allergan, Inc. | High viscosity macromolecular compositions for treating ocular conditions |
| US8821870B2 (en) * | 2008-07-18 | 2014-09-02 | Allergan, Inc. | Method for treating atrophic age related macular degeneration |
| CA2968112C (en) | 2016-05-26 | 2025-09-23 | Op-Hygiene Ip Gmbh | MAINTENANCE OF A DISPENSER INTENDED FOR AN INSTALLATION WITH MULTIPLE BATHROOMS |
| US11138621B2 (en) | 2019-05-23 | 2021-10-05 | Capital One Services, Llc | Normalization grid |
-
2008
- 2008-07-18 US US12/176,238 patent/US8821870B2/en active Active
-
2009
- 2009-07-13 ES ES13179231T patent/ES2720882T3/es active Active
- 2009-07-13 KR KR1020117003673A patent/KR20110047196A/ko not_active Ceased
- 2009-07-13 WO PCT/US2009/050373 patent/WO2010009034A2/en not_active Ceased
- 2009-07-13 EP EP19161922.0A patent/EP3524270B1/en active Active
- 2009-07-13 JP JP2011518816A patent/JP2011528656A/ja active Pending
- 2009-07-13 BR BRPI0915981-9A patent/BRPI0915981A2/pt not_active Application Discontinuation
- 2009-07-13 CN CN2009801368268A patent/CN102159246A/zh active Pending
- 2009-07-13 AU AU2009271168A patent/AU2009271168B2/en not_active Ceased
- 2009-07-13 CN CN201611271046.2A patent/CN107412778A/zh active Pending
- 2009-07-13 RU RU2011105409/15A patent/RU2521338C9/ru active
- 2009-07-13 ES ES09790328.0T patent/ES2574706T3/es active Active
- 2009-07-13 ES ES19161922T patent/ES2897560T3/es active Active
- 2009-07-13 EP EP09790328.0A patent/EP2307055B1/en active Active
- 2009-07-13 RU RU2014115647A patent/RU2668371C2/ru active
- 2009-07-13 CA CA2731270A patent/CA2731270C/en not_active Expired - Fee Related
- 2009-07-13 EP EP21196540.5A patent/EP3950002A1/en not_active Withdrawn
- 2009-07-13 EP EP13179231.9A patent/EP2664347B1/en active Active
-
2014
- 2014-07-07 US US14/324,630 patent/US10363214B2/en active Active
- 2014-08-22 JP JP2014169846A patent/JP6009511B2/ja not_active Expired - Fee Related
-
2016
- 2016-06-23 JP JP2016124732A patent/JP6132964B2/ja not_active Expired - Fee Related
-
2018
- 2018-09-19 RU RU2018133133A patent/RU2018133133A/ru not_active Application Discontinuation
-
2019
- 2019-07-19 US US16/516,411 patent/US20190336441A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011528656A5 (enExample) | ||
| JP6700348B2 (ja) | 持続型薬物送達インプラント | |
| RU2018133133A (ru) | Способ лечения атрофической возрастной макулярной дегенерации | |
| JP2008540552A5 (enExample) | ||
| US20240082150A1 (en) | Ocular compositions | |
| JP2018500394A5 (enExample) | ||
| RU2672596C2 (ru) | Биологически разлагаемые или биологически разрушаемые микросферы или микрочастицы длительного высвобождения, суспендированные в затвердевающем депообразующем инъекцируемом лекарственном составе | |
| Goyal et al. | Current nanotechnological strategies for treating glaucoma | |
| JP2007535552A5 (enExample) | ||
| RU2017123358A (ru) | Составы на основе сунитиниба и способы их применения для лечения глазных заболеваний | |
| JP2017537985A5 (enExample) | ||
| CA2772795A1 (en) | Injectable aqueous ophthalmic composition and method of use therefor | |
| JP2009535422A5 (enExample) | ||
| JP2013526572A5 (enExample) | ||
| BRPI0708622A2 (pt) | terapia ocular usando agentes que ativam a sirtuina | |
| JP2007535564A5 (enExample) | ||
| CN103990185B (zh) | 一种卡拉胶和明胶微球栓塞剂及其制备方法 | |
| Gavini et al. | Biodegradable microspheres as intravitreal delivery systems for prolonged drug release. What is their eminence in the nanoparticle era? | |
| JP2013523748A5 (enExample) | ||
| WO2005018608A1 (ja) | 微粒子テノン嚢下投与ドラッグデリバリーシステム | |
| CA3124280A1 (en) | Ocular compositions | |
| JP2024539445A5 (enExample) | ||
| JP2005132737A (ja) | 埋込型製剤の薬物保持担体 | |
| RU2021117158A (ru) | Улучшенные агрегированные микрочастицы |