JP2008540552A5 - - Google Patents

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Publication number
JP2008540552A5
JP2008540552A5 JP2008511301A JP2008511301A JP2008540552A5 JP 2008540552 A5 JP2008540552 A5 JP 2008540552A5 JP 2008511301 A JP2008511301 A JP 2008511301A JP 2008511301 A JP2008511301 A JP 2008511301A JP 2008540552 A5 JP2008540552 A5 JP 2008540552A5
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JP
Japan
Prior art keywords
ophthalmic composition
composition according
brimonidine
administered
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008511301A
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English (en)
Japanese (ja)
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JP2008540552A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/018019 external-priority patent/WO2006122165A2/en
Publication of JP2008540552A publication Critical patent/JP2008540552A/ja
Publication of JP2008540552A5 publication Critical patent/JP2008540552A5/ja
Pending legal-status Critical Current

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JP2008511301A 2005-05-10 2006-05-09 増大した前部クリアランス速度を有するα−２アドレナリン受容体アゴニストを用いる眼科治療 Pending JP2008540552A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67977105P 2005-05-10 2005-05-10
PCT/US2006/018019 WO2006122165A2 (en) 2005-05-10 2006-05-09 Ocular therapy using alpha-2 adrenergic receptor agonists having enhanced anterior clearance rates

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011209152A Division JP2012046530A (ja) 2005-05-10 2011-09-26 増大した前眼部クリアランス速度を有するα−２アドレナリン受容体アゴニストを用いる眼科治療

Publications (2)

Publication Number Publication Date
JP2008540552A JP2008540552A (ja) 2008-11-20
JP2008540552A5 true JP2008540552A5 (enExample) 2011-06-16

Family

ID=37397258

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008511301A Pending JP2008540552A (ja) 2005-05-10 2006-05-09 増大した前部クリアランス速度を有するα−２アドレナリン受容体アゴニストを用いる眼科治療
JP2011209152A Pending JP2012046530A (ja) 2005-05-10 2011-09-26 増大した前眼部クリアランス速度を有するα−２アドレナリン受容体アゴニストを用いる眼科治療
JP2014156852A Pending JP2015013863A (ja) 2005-05-10 2014-07-31 増大した前眼部クリアランス速度を有するα−２アドレナリン受容体アゴニストを用いる眼科治療

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2011209152A Pending JP2012046530A (ja) 2005-05-10 2011-09-26 増大した前眼部クリアランス速度を有するα−２アドレナリン受容体アゴニストを用いる眼科治療
JP2014156852A Pending JP2015013863A (ja) 2005-05-10 2014-07-31 増大した前眼部クリアランス速度を有するα−２アドレナリン受容体アゴニストを用いる眼科治療

Country Status (8)

Country Link
US (3) US7931909B2 (enExample)
EP (2) EP1879553B1 (enExample)
JP (3) JP2008540552A (enExample)
AU (1) AU2006244083A1 (enExample)
BR (1) BRPI0608978A2 (enExample)
CA (1) CA2603069C (enExample)
ES (1) ES2798259T3 (enExample)
WO (1) WO2006122165A2 (enExample)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
BRPI0613034A8 (pt) 2005-07-14 2018-01-02 Lipothera Inc formulação injetável para acúmulo de tecido adiposo, formulação injetável e método para o tratamento de acúmulo de gordura, e, método para reduzir o tecido adiposo.
EP1924292A2 (en) * 2005-09-16 2008-05-28 Allergan, Inc. Compositions and methods for the intraocular transport of therapeutic agents
US20070203144A1 (en) * 2006-01-17 2007-08-30 Allergan, Inc. Use of Memantine and Brimonidine to Attenuate Vitreoretinal Vascular Endothelial Growth Factor (VEGF) Protein Levels in Animals
MX2009004198A (es) * 2006-10-17 2009-10-19 Lithera Inc Metodos, composiciones y formulaciones para el tratamiento de enfermedad ocular tiroidea.
US8969415B2 (en) * 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
US8492334B2 (en) * 2007-06-21 2013-07-23 Yale University Sustained intraocular delivery of drugs from biodegradable polymeric microparticles
US20090081277A1 (en) * 2007-09-21 2009-03-26 Allergan, Inc. Pharmaceutical formulations and methods for treating ocular conditions
GB0724558D0 (en) 2007-12-15 2008-01-30 Sharma Anant Optical correction
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
EP2276439A4 (en) 2008-05-12 2013-11-27 Univ Utah Res Found DEVICE AND CORRESPONDING METHODS FOR INTRAOCULAR MEDICAMENT ADMINISTRATION
US9095506B2 (en) 2008-11-17 2015-08-04 Allergan, Inc. Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof
US8034813B2 (en) * 2008-11-18 2011-10-11 Bausch & Lomb Incorporated Polymorphs of brimonidine pamoate
US9636255B2 (en) 2009-02-13 2017-05-02 Dose Medical Corporation Uveoscleral drug delivery implant and methods for implanting the same
US8633181B2 (en) 2009-04-09 2014-01-21 Rutgers, The State University Of New Jersey Treatment of cutaneous hemangioma
JP5937004B2 (ja) 2009-05-18 2016-06-22 ドーズ メディカル コーポレーションＤｏｓｅ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ 薬剤溶出眼内インプラント
WO2012071476A2 (en) 2010-11-24 2012-05-31 David Haffner Drug eluting ocular implant
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US8299079B2 (en) * 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
WO2010135731A1 (en) * 2009-05-22 2010-11-25 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
US9132084B2 (en) 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
KR20170095402A (ko) 2009-11-09 2017-08-22 알러간, 인코포레이티드 모발 성장을 촉진하기 위한 조성물 및 방법
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
US8492422B2 (en) 2010-09-16 2013-07-23 Allergan, Inc. Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for treating skin diseases and conditions
US9370444B2 (en) 2010-10-12 2016-06-21 Emmett T. Cunningham, JR. Subconjunctival conformer device and uses thereof
US8915877B2 (en) 2010-10-12 2014-12-23 Emmett T. Cunningham, JR. Glaucoma drainage device and uses thereof
GEP201606551B (en) 2010-11-24 2016-10-10 Novamedica Llc Selective, lipophilic, and long-acting beta agonists monotherapeutic formulations tions and methods for cosmetic treatment of adiposity and contour bulging
JP6030568B2 (ja) 2010-12-16 2016-11-24 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ ケモカイン受容体調節因子としての新規１，２−ビス−スルホンアミド誘導体
AU2011344146B2 (en) 2010-12-16 2017-03-16 Allergan, Inc. Sulfur derivatives as chemokine receptor modulators
US8349005B2 (en) 2011-01-03 2013-01-08 Masatoshi Murata Method for burying implant to choroid
CA2827005A1 (en) 2011-02-11 2012-08-16 Allergan, Inc. Novel 1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as n-formyl peptide receptor like-1 (fprl-1) receptor modulators
US8653299B2 (en) 2011-03-17 2014-02-18 Allergan, Inc. Dihydronaphthalene and naphthalene derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
AU2012340806B2 (en) 2011-11-21 2017-10-19 Allergan, Inc. Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3H-imidazole derivatives for treating retinal diseases
US20130190324A1 (en) * 2011-12-23 2013-07-25 The Regents Of The University Of Colorado, A Body Corporate Topical ocular drug delivery
US20130197002A1 (en) 2012-01-30 2013-08-01 Allergan, Inc. Brimonidine for treating visual disorders mediated by central visual projections from the eye
PL2820010T3 (pl) 2012-03-01 2018-11-30 Allergan, Inc. Pochodne benzofurano-2-sulfonamidu jako modulatory receptora chemokinowego
TWI663985B (zh) 2012-09-27 2019-07-01 美商歐樂根公司 用於持續釋放蛋白質之可生物降解的藥物傳遞系統
CN105142710A (zh) 2013-01-15 2015-12-09 科罗拉多州立大学董事会,公司实体 泪腺系统给药装置
AU2014216112B2 (en) 2013-02-15 2019-02-21 Allergan, Inc. Sustained drug delivery implant
EP2970239B1 (en) 2013-03-12 2018-10-10 Allergan, Inc. Sulfonamide derivatives as chemokine receptor modulators
US10517759B2 (en) 2013-03-15 2019-12-31 Glaukos Corporation Glaucoma stent and methods thereof for glaucoma treatment
KR20150143439A (ko) 2013-03-15 2015-12-23 알레간 인코포레이티드 무스카린성 효능제
WO2015084869A1 (en) 2013-12-02 2015-06-11 Allergan, Inc. Benzothiophene sulfonamides derivatives as chemokine receptor modulators
KR101587483B1 (ko) * 2014-03-28 2016-01-21 동아대학교 산학협력단 미토콘드리아성 복합체 ⅰ 저해제를 유효성분으로 함유하는 증식성 유리체망막병증의 예방 또는 치료용 약학적 조성물
EP3148491B1 (en) 2014-05-29 2020-07-01 Glaukos Corporation Implants with controlled drug delivery features and manufacturing method for said implants
SG11201700777VA (en) 2014-08-04 2017-02-27 Nuevolution As Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
US11925578B2 (en) 2015-09-02 2024-03-12 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
EP3380040B1 (en) 2015-11-23 2023-04-19 The Regents of The University of Colorado, A Body Corporate Lacrimal system for drug delivery
JP7003110B2 (ja) 2016-04-20 2022-01-20 ドーズ メディカル コーポレーション 生体吸収性眼球薬物送達デバイス
US11207211B2 (en) 2016-05-20 2021-12-28 The Regents Of The University Of Colorado, A Body Corporate Lacrimal drug delivery device
EP4520828A3 (en) 2016-11-15 2025-07-09 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
AU2017388230A1 (en) * 2016-12-27 2019-08-15 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
JP7416700B2 (ja) * 2017-11-14 2024-01-17 ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド 増殖性硝子体網膜症および上皮間葉転換と関連付けられる状態の治療のためのｒｕｎｘ１阻害の方法
SG11202101730SA (en) * 2018-08-21 2021-03-30 Allergan Inc The use of alpha-2-adrenergic receptor agonists for improving vision
CA3144406A1 (en) 2019-06-27 2020-12-30 Layerbio, Inc. Ocular device delivery methods and systems
EP4076661A1 (en) 2019-12-20 2022-10-26 Nuevolution A/S Compounds active towards nuclear receptors
EP4076657A1 (en) 2019-12-20 2022-10-26 Nuevolution A/S Compounds active towards nuclear receptors
EP4126875A1 (en) 2020-03-31 2023-02-08 Nuevolution A/S Compounds active towards nuclear receptors
WO2021198955A1 (en) 2020-03-31 2021-10-07 Nuevolution A/S Compounds active towards nuclear receptors
IL300724A (en) * 2020-08-21 2023-04-01 Oculotherapy Llc Methods of neuroprotection and its uses
US20230301993A1 (en) * 2020-08-21 2023-09-28 Vyluma Inc. Low-Dose Ophthalmic Compositions and Methods

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
JPS58126435U (ja) * 1982-02-19 1983-08-27 オリンパス光学工業株式会社 Ｔｔｌオ−トストロボ用絞り制御回路
US4521210A (en) * 1982-12-27 1985-06-04 Wong Vernon G Eye implant for relieving glaucoma, and device and method for use therewith
US4853224A (en) * 1987-12-22 1989-08-01 Visionex Biodegradable ocular implants
US4997652A (en) * 1987-12-22 1991-03-05 Visionex Biodegradable ocular implants
US5164188A (en) * 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
KR0185215B1 (ko) * 1990-11-30 1999-05-01 요시다 쇼오지 서방성 안구삽입용 약제
WO1995003009A1 (en) * 1993-07-22 1995-02-02 Oculex Pharmaceuticals, Inc. Method of treatment of macular degeneration
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US6369116B1 (en) * 1995-06-02 2002-04-09 Oculex Pharmaceuticals, Inc. Composition and method for treating glaucoma
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
US6194415B1 (en) * 1995-06-28 2001-02-27 Allergan Sales, Inc. Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury
ES2232005T3 (es) * 1997-08-11 2005-05-16 Allergan, Inc. Dispositivo de implante biodegradable esteril que contiene retinoide con biocompatibilidad mejorada y metodo de preparacion.
WO2004073708A1 (en) * 1998-12-17 2004-09-02 Dean Thomas R Brinzolamide and brimonidine for treating ocular conditions
US6331313B1 (en) * 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
AUPQ496500A0 (en) * 2000-01-06 2000-02-03 University Of Sydney, The Kit
WO2002058730A2 (en) * 2000-11-01 2002-08-01 Allergan, Inc. Compositions for treatment of ocular neovascularization
US6699493B2 (en) * 2000-11-29 2004-03-02 Oculex Pharmaceuticals, Inc. Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
US20030114460A1 (en) * 2001-12-14 2003-06-19 Allergan Sales, Inc. Pharmaceutical conjugates with enhanced pharmacokinetic characteristics
CA2479351C (en) 2002-03-18 2012-05-15 Novartis Ag Topical composition comprising a cyclofructan, a carrier and a drug
US20070042951A1 (en) * 2003-10-08 2007-02-22 Allergan, Inc. Pharmaceutical compositions comprising alpha-2-adrenergics and trefoil factor family peptides
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US20050244469A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Extended therapeutic effect ocular implant treatments
US8425929B2 (en) 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
US8685435B2 (en) 2004-04-30 2014-04-01 Allergan, Inc. Extended release biodegradable ocular implants

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