JP2011505341A - 炎症性、心血管およびｃｎｓ障害を治療するビアリールｐｄｅ４抑制剤 - Google Patents

炎症性、心血管およびｃｎｓ障害を治療するビアリールｐｄｅ４抑制剤 Download PDF

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JP2011505341A
JP2011505341A JP2010535064A JP2010535064A JP2011505341A JP 2011505341 A JP2011505341 A JP 2011505341A JP 2010535064 A JP2010535064 A JP 2010535064A JP 2010535064 A JP2010535064 A JP 2010535064A JP 2011505341 A JP2011505341 A JP 2011505341A
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alkyl
mmol
nhc
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phenyl
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JP2011505341A5 (fr
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シング，ジャスバー
イー． ガーネイ，マーク
バージン，アレックス
サンダナヤカ，ヴィンセント
キセリョフ，アレクサンダー
モッタ，アダリー
シュルツ，ゲイリー
ハタガン，ジョールジェッタ
ハーゲン，ティモシー
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デコード ジェネティクス イーエイチエフ
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JP2016512259A (ja) * 2013-03-14 2016-04-25 ダート・ニューロサイエンス・（ケイマン）・リミテッド Ｐｄｅ４阻害剤としての置換ピリジン及びピラジン化合物
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JP2013532734A (ja) * 2010-08-04 2013-08-19 ユニバーシティ オブ バージニア パテント ファウンデーション 炎症性疾患を治療するための組成物及び方法
US9617197B2 (en) 2010-08-04 2017-04-11 University Of Virginia Patent Foundation Compositions and methods for treating inflammatory diseases
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JP2018062529A (ja) * 2013-03-14 2018-04-19 ダート・ニューロサイエンス・（ケイマン）・リミテッド Ｐｄｅ４阻害剤としての置換ピリジン及びピラジン化合物
JP2019522005A (ja) * 2016-07-05 2019-08-08 グアンジョウ マキシノベル ファーマシューティカルズ カンパニー リミテッド 芳香族アセチレンまたは芳香族エチレン系化合物、その中間体、製造方法、薬物組成物および使用
US11078192B2 (en) 2016-07-05 2021-08-03 Guangzhou Maxinovel Pharmaceuticals Co., Ltd. Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof
JP6994496B2 (ja) 2016-07-05 2022-01-14 グアンジョウ マキシノベル ファーマシューティカルズ カンパニー リミテッド 芳香族アセチレンまたは芳香族エチレン系化合物、その中間体、製造方法、薬物組成物および使用
US11384048B2 (en) 2017-12-29 2022-07-12 Guangzhou Maxinovel Pharmaceuticals Co., Ltd. Aromatic vinyl or aromatic ethyl derivative, preparation method therefor, intermediate, pharmaceutical composition, and application

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WO2009067600A3 (fr) 2009-07-30
EP2222638A2 (fr) 2010-09-01
WO2009067600A2 (fr) 2009-05-28
CN102089279A (zh) 2011-06-08

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