JP2011168587A5 - - Google Patents
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- JP2011168587A5 JP2011168587A5 JP2011026718A JP2011026718A JP2011168587A5 JP 2011168587 A5 JP2011168587 A5 JP 2011168587A5 JP 2011026718 A JP2011026718 A JP 2011026718A JP 2011026718 A JP2011026718 A JP 2011026718A JP 2011168587 A5 JP2011168587 A5 JP 2011168587A5
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- 150000003839 salts Chemical class 0.000 claims 20
- 238000000634 powder X-ray diffraction Methods 0.000 claims 8
- 239000000126 substance Substances 0.000 claims 8
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 5
- 229910052802 copper Inorganic materials 0.000 claims 5
- 239000010949 copper Substances 0.000 claims 5
- 238000000371 solid-state nuclear magnetic resonance spectroscopy Methods 0.000 claims 5
- 238000001228 spectrum Methods 0.000 claims 5
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 3
- MIOPJNTWMNEORI-UHFFFAOYSA-N camphorsulfonic acid Chemical class C1CC2(CS(O)(=O)=O)C(=O)CC1C2(C)C MIOPJNTWMNEORI-UHFFFAOYSA-N 0.000 claims 2
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 claims 2
- HMABYWSNWIZPAG-UHFFFAOYSA-N rucaparib Chemical compound C1=CC(CNC)=CC=C1C(N1)=C2CCNC(=O)C3=C2C1=CC(F)=C3 HMABYWSNWIZPAG-UHFFFAOYSA-N 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30427710P | 2010-02-12 | 2010-02-12 | |
| US61/304,277 | 2010-02-12 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015086722A Division JP6013551B2 (ja) | 2010-02-12 | 2015-04-21 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011168587A JP2011168587A (ja) | 2011-09-01 |
| JP2011168587A5 true JP2011168587A5 (enExample) | 2014-02-20 |
| JP5745283B2 JP5745283B2 (ja) | 2015-07-08 |
Family
ID=43859823
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011026718A Active JP5745283B2 (ja) | 2010-02-12 | 2011-02-10 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2015086722A Active JP6013551B2 (ja) | 2010-02-12 | 2015-04-21 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2016183846A Active JP6371350B2 (ja) | 2010-02-12 | 2016-09-21 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2018132270A Active JP6640931B2 (ja) | 2010-02-12 | 2018-07-12 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2019235421A Withdrawn JP2020050671A (ja) | 2010-02-12 | 2019-12-26 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2021078485A Pending JP2021107460A (ja) | 2010-02-12 | 2021-05-06 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015086722A Active JP6013551B2 (ja) | 2010-02-12 | 2015-04-21 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2016183846A Active JP6371350B2 (ja) | 2010-02-12 | 2016-09-21 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2018132270A Active JP6640931B2 (ja) | 2010-02-12 | 2018-07-12 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2019235421A Withdrawn JP2020050671A (ja) | 2010-02-12 | 2019-12-26 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
| JP2021078485A Pending JP2021107460A (ja) | 2010-02-12 | 2021-05-06 | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
Country Status (32)
Families Citing this family (32)
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| JP5745283B2 (ja) * | 2010-02-12 | 2015-07-08 | ファイザー・インク | ８−フルオロ−２−｛４−［（メチルアミノ）メチル］フェニル｝−１，３，４，５−テトラヒドロ−６Ｈ−アゼピノ［５，４，３−ｃｄ］インドール−６−オンの塩および多形体 |
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| KR20190018643A (ko) | 2016-05-16 | 2019-02-25 | 풀마젠 테라퓨틱스 (애즈마) 리미티드 | 퀴놀린 유도체의 결정 |
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| CN111217818A (zh) * | 2018-11-27 | 2020-06-02 | 台耀化学股份有限公司 | 芦卡帕尼樟脑磺酸盐的结晶、及制备三环化合物、芦卡帕尼及其樟脑磺酸盐结晶的方法 |
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