JP2010524470A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010524470A5 JP2010524470A5 JP2010504212A JP2010504212A JP2010524470A5 JP 2010524470 A5 JP2010524470 A5 JP 2010524470A5 JP 2010504212 A JP2010504212 A JP 2010504212A JP 2010504212 A JP2010504212 A JP 2010504212A JP 2010524470 A5 JP2010524470 A5 JP 2010524470A5
- Authority
- JP
- Japan
- Prior art keywords
- gene construct
- construct encoding
- specific activity
- ketolate reductoisomerase
- host cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000623 proteins and genes Proteins 0.000 claims description 31
- 230000000694 effects Effects 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 24
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims description 12
- 230000001580 bacterial effect Effects 0.000 claims description 11
- 241000894007 species Species 0.000 claims description 11
- 238000003556 assay Methods 0.000 claims description 10
- 241000588724 Escherichia coli Species 0.000 claims description 9
- 102000004169 proteins and genes Human genes 0.000 claims description 9
- 108090000790 Enzymes Proteins 0.000 claims description 8
- 102000004190 Enzymes Human genes 0.000 claims description 8
- AMIMRNSIRUDHCM-UHFFFAOYSA-N Isopropylaldehyde Chemical compound CC(C)C=O AMIMRNSIRUDHCM-UHFFFAOYSA-N 0.000 claims description 8
- ACFIXJIJDZMPPO-NNYOXOHSSA-N NADPH Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](OP(O)(O)=O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 ACFIXJIJDZMPPO-NNYOXOHSSA-N 0.000 claims description 8
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 8
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 claims description 8
- 229910052700 potassium Inorganic materials 0.000 claims description 8
- 239000011591 potassium Substances 0.000 claims description 8
- JTEYKUFKXGDTEU-UHFFFAOYSA-N 2,3-dihydroxy-3-methylbutanoic acid Chemical compound CC(C)(O)C(O)C(O)=O JTEYKUFKXGDTEU-UHFFFAOYSA-N 0.000 claims description 6
- WTLNOANVTIKPEE-UHFFFAOYSA-N 2-acetyloxypropanoic acid Chemical compound OC(=O)C(C)OC(C)=O WTLNOANVTIKPEE-UHFFFAOYSA-N 0.000 claims description 6
- 229920001184 polypeptide Polymers 0.000 claims description 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 5
- QHKABHOOEWYVLI-UHFFFAOYSA-N 3-methyl-2-oxobutanoic acid Chemical compound CC(C)C(=O)C(O)=O QHKABHOOEWYVLI-UHFFFAOYSA-N 0.000 claims description 4
- 230000002068 genetic effect Effects 0.000 claims description 4
- 230000000813 microbial effect Effects 0.000 claims description 4
- 238000012216 screening Methods 0.000 claims description 4
- 108010000700 Acetolactate synthase Proteins 0.000 claims description 3
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims description 3
- 102000007698 Alcohol dehydrogenase Human genes 0.000 claims description 3
- 102000004867 Hydro-Lyases Human genes 0.000 claims description 3
- 108090001042 Hydro-Lyases Proteins 0.000 claims description 3
- 102000004195 Isomerases Human genes 0.000 claims description 3
- 108090000769 Isomerases Proteins 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- CTMXBOCTJPQVDZ-UHFFFAOYSA-N 2,2-dihydroxy-3-methylbutanoic acid Chemical compound CC(C)C(O)(O)C(O)=O CTMXBOCTJPQVDZ-UHFFFAOYSA-N 0.000 claims description 2
- 108020004414 DNA Proteins 0.000 claims description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 2
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 150000004715 keto acids Chemical class 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 150000007523 nucleic acids Chemical group 0.000 claims description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 108010000200 Ketol-acid reductoisomerase Proteins 0.000 description 3
- 241000589516 Pseudomonas Species 0.000 description 3
- 241000186063 Arthrobacter Species 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- 241000186146 Brevibacterium Species 0.000 description 2
- 241000193403 Clostridium Species 0.000 description 2
- 241000186216 Corynebacterium Species 0.000 description 2
- 241000194033 Enterococcus Species 0.000 description 2
- 241000588722 Escherichia Species 0.000 description 2
- 101710148054 Ketol-acid reductoisomerase (NAD(+)) Proteins 0.000 description 2
- 101710099070 Ketol-acid reductoisomerase (NAD(P)(+)) Proteins 0.000 description 2
- 101710151482 Ketol-acid reductoisomerase (NADP(+)) Proteins 0.000 description 2
- 241000588748 Klebsiella Species 0.000 description 2
- 241000186660 Lactobacillus Species 0.000 description 2
- 241000179039 Paenibacillus Species 0.000 description 2
- 241000235648 Pichia Species 0.000 description 2
- 241000316848 Rhodococcus <scale insect> Species 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 2
- 241000607142 Salmonella Species 0.000 description 2
- 241000607598 Vibrio Species 0.000 description 2
- 241000588901 Zymomonas Species 0.000 description 2
- 239000012521 purified sample Substances 0.000 description 2
- 108010046716 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) Proteins 0.000 description 1
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 description 1
- 241000192700 Cyanobacteria Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 240000006024 Lactobacillus plantarum Species 0.000 description 1
- 235000013965 Lactobacillus plantarum Nutrition 0.000 description 1
- 241000235070 Saccharomyces Species 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 229940072205 lactobacillus plantarum Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91249107P | 2007-04-18 | 2007-04-18 | |
| US60/912,491 | 2007-04-18 | ||
| PCT/US2008/060466 WO2008130995A2 (en) | 2007-04-18 | 2008-04-16 | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014107940A Division JP5908026B2 (ja) | 2007-04-18 | 2014-05-26 | 活性の高いケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生成 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010524470A JP2010524470A (ja) | 2010-07-22 |
| JP2010524470A5 true JP2010524470A5 (enExample) | 2011-05-06 |
| JP5582576B2 JP5582576B2 (ja) | 2014-09-03 |
Family
ID=39872591
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010504212A Expired - Fee Related JP5582576B2 (ja) | 2007-04-18 | 2008-04-16 | 活性の高いケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生成 |
| JP2014107940A Active JP5908026B2 (ja) | 2007-04-18 | 2014-05-26 | 活性の高いケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生成 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014107940A Active JP5908026B2 (ja) | 2007-04-18 | 2014-05-26 | 活性の高いケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生成 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7910342B2 (enExample) |
| EP (2) | EP2134849B1 (enExample) |
| JP (2) | JP5582576B2 (enExample) |
| KR (1) | KR101573775B1 (enExample) |
| CN (1) | CN101680007A (enExample) |
| AU (1) | AU2008242978B2 (enExample) |
| BR (1) | BRPI0808600A2 (enExample) |
| CA (1) | CA2683898C (enExample) |
| ES (1) | ES2426070T3 (enExample) |
| MX (1) | MX2009011192A (enExample) |
| NZ (1) | NZ579780A (enExample) |
| WO (1) | WO2008130995A2 (enExample) |
| ZA (1) | ZA200906811B (enExample) |
Families Citing this family (127)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| US8956850B2 (en) * | 2008-06-05 | 2015-02-17 | Butamax Advanced Biofuels Llc | Enhanced pyruvate to acetolactate conversion in yeast |
| PL389665A1 (pl) | 2007-02-09 | 2010-07-05 | The Regents of the University of CaliforniaThe Regents of the University of California | Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy |
| TWI568847B (zh) | 2007-03-16 | 2017-02-01 | 奇諾麥提卡公司 | 用於１，４-丁二醇及其前驅物之生物合成的組合物及方法 |
| US20090111154A1 (en) * | 2007-04-04 | 2009-04-30 | The Regents Of The University Of California | Butanol production by recombinant microorganisms |
| WO2008130995A2 (en) | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
| CN101903530A (zh) * | 2007-10-12 | 2010-12-01 | 加利福尼亚大学董事会 | 被改造以产生异丙醇的微生物 |
| US8193402B2 (en) | 2007-12-03 | 2012-06-05 | Gevo, Inc. | Renewable compositions |
| EP2225351A4 (en) | 2007-12-03 | 2016-11-09 | Gevo Inc | RENEWABLE COMPOSITIONS |
| US8114641B2 (en) * | 2007-12-10 | 2012-02-14 | Synthetic Genomics, Inc. | Methylbutanol as an advanced biofuel |
| CA3081506A1 (en) | 2008-03-05 | 2009-09-11 | Genomatica, Inc. | Long chain alcohol-producing organisms |
| US7799545B2 (en) | 2008-03-27 | 2010-09-21 | Genomatica, Inc. | Microorganisms for the production of adipic acid and other compounds |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| CA2722680A1 (en) * | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| EP3514242A3 (en) | 2008-09-10 | 2019-08-28 | Genomatica, Inc. | Microrganisms for the production of 1,4-butanediol |
| MX2011003313A (es) * | 2008-09-29 | 2011-06-16 | Butamax Tm Advanced Biofuels | Actividad enzimatica de fe-s heterologa aumentada en levadura. |
| EP2821484B1 (en) * | 2008-09-29 | 2016-06-29 | Butamax Advanced Biofuels LLC | Identification and use of Bacterial [2Fe-2S] dihydroxy-acid dehydratases |
| US8637281B2 (en) * | 2008-09-29 | 2014-01-28 | Butamax(Tm) Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| BRPI0921734A2 (pt) | 2008-10-31 | 2019-01-08 | California Inst Of Techn | micro-organismos criados geneticamente capazes de produzir compostos-alvo sob condições anaeróbicas |
| US8828694B2 (en) * | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
| US8465964B2 (en) * | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| AU2009324539B2 (en) * | 2008-12-10 | 2015-10-01 | Synthetic Genomics, Inc. | Production of branched-chain alcohols by photosynthetic microorganisms |
| WO2010071697A1 (en) | 2008-12-16 | 2010-06-24 | Genomatica, Inc. | Microorganisms and methods for conversion of syngas and other carbon sources to useful products |
| WO2010075504A2 (en) * | 2008-12-23 | 2010-07-01 | Gevo, Inc. | Engineered microorganisms for the production of one or more target compounds |
| US8557562B2 (en) * | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
| US8795992B2 (en) * | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
| US8455225B2 (en) * | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
| US8614085B2 (en) * | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
| EP2419517A2 (en) * | 2009-04-13 | 2012-02-22 | Butamax(TM) Advanced Biofuels LLC | Method for producing butanol using extractive fermentation |
| EP4273255A3 (en) | 2009-05-07 | 2024-01-03 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of hexamethylenediamine |
| EP3696158A1 (en) | 2009-06-04 | 2020-08-19 | Genomatica, Inc. | Process of separating components of a fermentation broth |
| CN107384846B (zh) | 2009-06-04 | 2021-08-10 | 基因组股份公司 | 生产1,4-丁二醇的微生物和相关方法 |
| EP2464736A4 (en) * | 2009-08-12 | 2013-07-31 | Gevo Inc | PATIENT LOCALIZATION OF CYTOSOLIC ISOBUTANOL FOR THE MANUFACTURE OF ISOBUTANOL |
| US9260708B2 (en) * | 2009-09-29 | 2016-02-16 | Butamax Advanced Biofuels Llc | Yeast production host cells |
| JP2013505739A (ja) * | 2009-09-29 | 2013-02-21 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 乳酸菌におけるアセト乳酸誘導生成物への改善されたフラックス |
| JP5805094B2 (ja) * | 2009-09-29 | 2015-11-04 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 高有効性のケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生産 |
| US20110195505A1 (en) * | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| PH12012500729A1 (en) | 2009-10-13 | 2012-10-29 | Genomatica Inc | Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds and methods related thereto |
| JP2013511284A (ja) | 2009-11-23 | 2013-04-04 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | オスモライトの添加を伴う抽出発酵を用いたブタノールの生成方法 |
| CN102656272A (zh) | 2009-11-23 | 2012-09-05 | 布特马斯先进生物燃料有限责任公司 | 使用添加电解质的萃取发酵来生产丁醇的方法 |
| WO2011066076A1 (en) | 2009-11-25 | 2011-06-03 | Genomatica, Inc. | Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone |
| US20110137088A1 (en) * | 2009-12-03 | 2011-06-09 | Bp Corporation North America Inc. | Methods and Apparatuses for Producing Renewable Materials From Inhibiting Compounds |
| KR20120099509A (ko) | 2009-12-29 | 2012-09-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 재조합 숙주 세포에서 육탄당 키나아제의 발현 |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| BR112012016883A2 (pt) | 2010-01-08 | 2018-06-05 | Gevo Inc | metodos integrados de preparar produsot quimicos renovaveis |
| US8530221B2 (en) | 2010-01-14 | 2013-09-10 | Ls9, Inc. | Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells |
| US8574406B2 (en) * | 2010-02-09 | 2013-11-05 | Butamax Advanced Biofuels Llc | Process to remove product alcohol from a fermentation by vaporization under vacuum |
| WO2011103300A2 (en) | 2010-02-17 | 2011-08-25 | Butamax(Tm) Advanced Biofuels Llc | Improving activity of fe-s cluster requiring proteins |
| US8048661B2 (en) | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
| US8637286B2 (en) | 2010-02-23 | 2014-01-28 | Genomatica, Inc. | Methods for increasing product yields |
| CA2791219C (en) | 2010-03-15 | 2015-11-24 | Total Research & Technology Feluy | Production of propylene via simultaneous dehydration and skeletal isomerisation of isobutanol on acid catalysts followed by metathesis |
| WO2011113834A1 (en) | 2010-03-15 | 2011-09-22 | Total Petrochemicals Research Feluy | Simultaneous dehydration and skeletal isomerisation of isobutanol on acid catalysts |
| EP2374780A1 (en) | 2010-04-09 | 2011-10-12 | Total Petrochemicals Research Feluy | Production of propylene via simultaneous dehydration and skeletal isomerisation of isobutanol on acid catalysts followed by metathesis |
| EP2374781A1 (en) | 2010-04-09 | 2011-10-12 | Total Petrochemicals Research Feluy | Simultaneous dehydration and skeletal isomerisation of isobutanol on acid catalysts |
| US8373012B2 (en) | 2010-05-07 | 2013-02-12 | Gevo, Inc. | Renewable jet fuel blendstock from isobutanol |
| AU2011268247B2 (en) | 2010-06-16 | 2017-05-11 | Butamax(Tm) Advanced Biofuels Llc | Oxygenated butanol gasoline composition having good driveability performance |
| NZ603487A (en) * | 2010-06-16 | 2015-03-27 | Butamax Tm Advanced Biofuels | Oxygenated butanol gasoline composition having good driveability performance |
| AU2011268326B2 (en) | 2010-06-17 | 2015-02-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| EP2582823A1 (en) | 2010-06-18 | 2013-04-24 | Butamax(tm) Advanced Biofuels LLC | Supplementation of fatty acids for improving alcohol productivity |
| US9040263B2 (en) | 2010-07-28 | 2015-05-26 | Butamax Advanced Biofuels Llc | Production of alcohol esters and in situ product removal during alcohol fermentation |
| US9012190B2 (en) | 2011-06-15 | 2015-04-21 | Butamax Advanced Biofuels Llc | Use of thiamine and nicotine adenine dinucleotide for butanol production |
| HUE044304T2 (hu) | 2010-06-18 | 2019-10-28 | Butamax Tm Advanced Biofuels | Olajból nyert oldószerek kivonása alkoholeltávolításra extraháló fermentációban |
| BR112013002357A2 (pt) | 2010-08-03 | 2016-05-24 | Total Res & Technology Feluy | processo para fazer olefinas a partir de metanol e isobutanol |
| WO2012016786A1 (en) | 2010-08-03 | 2012-02-09 | Total Petrochemicals Research Feluy | Process to make olefins from isobutanol |
| US9079813B2 (en) | 2010-08-03 | 2015-07-14 | Total Research & Technology Feluy | Process to make propylene from isobutanol by dehydration and subsequent cracking |
| CN103153920B (zh) | 2010-08-03 | 2015-04-15 | 道达尔研究技术弗吕公司 | 由异丁醇制造烯烃的方法 |
| WO2012027642A1 (en) * | 2010-08-27 | 2012-03-01 | Gevo, Inc. | Balanced four-step pathways to renewable butanols |
| EP2614138B1 (en) | 2010-09-07 | 2017-08-30 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| WO2012038247A1 (en) | 2010-09-24 | 2012-03-29 | Total Petrochemicals Research Feluy | Production of isoprene from iso-butanol |
| WO2012071121A1 (en) * | 2010-11-24 | 2012-05-31 | Gevo, Inc. | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids |
| FR2969147B1 (fr) | 2010-12-21 | 2013-01-04 | Total Raffinage Marketing | Production d'additifs pour carburant par deshydratation et isomerisation squelettique simultanee d'isobutanol sur des catalyseurs acides suivies par une etherification |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| US8759044B2 (en) | 2011-03-23 | 2014-06-24 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| US8765425B2 (en) | 2011-03-23 | 2014-07-01 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| EP2689014B1 (en) * | 2011-03-24 | 2019-04-24 | Butamax (TM) Advanced Biofuels LLC | Host cells and methods for production of isobutanol |
| EP2699618A4 (en) | 2011-04-19 | 2014-12-17 | Gevo Inc | VARIATIONS OF A PRINS REACTION FOR THE PREPARATION OF 2,5-DIMETHYLHEXADIENE FROM ISOBUTANOL |
| US20140295512A1 (en) * | 2011-06-16 | 2014-10-02 | California Institute Of Technology | Ketol-Acid Reductoisomerases With Improved Performance Properties |
| US20130164795A1 (en) | 2011-06-17 | 2013-06-27 | Butamax(Tm) Advanced Biofuels Llc | Co-products from biofuel production processes and methods of making |
| US9238828B2 (en) | 2011-07-28 | 2016-01-19 | Butamax Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
| AU2012347687A1 (en) | 2011-12-09 | 2014-05-29 | Butamax Advanced Biofuels Llc | Process to remove product alcohols from fermentation broth by multistep flash evaporation |
| EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
| AU2012362144A1 (en) | 2011-12-30 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
| JP2015510774A (ja) | 2012-03-23 | 2015-04-13 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ブタノール産生菌用培地の酢酸補給 |
| AU2013266727A1 (en) | 2012-05-11 | 2014-11-06 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| US9677045B2 (en) | 2012-06-04 | 2017-06-13 | Genomatica, Inc. | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds |
| US20140024064A1 (en) | 2012-07-23 | 2014-01-23 | Butamax(Tm) Advanced Biofuels Llc | Processes and systems for the production of fermentative alcohols |
| AU2013295626B2 (en) | 2012-07-26 | 2018-02-01 | Butamax Advanced Biofuels Llc | Butanol purification |
| WO2014028642A1 (en) | 2012-08-17 | 2014-02-20 | Easel Biotechnologies, Llc | Two stage production of higher alcohols |
| AU2013305714A1 (en) | 2012-08-22 | 2015-02-05 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| WO2014043288A1 (en) | 2012-09-12 | 2014-03-20 | Butamax Advanced Biofuels Llc | Processes and systems for the production of fermentation products |
| CN104981544B (zh) | 2012-09-21 | 2018-05-15 | 布特马斯先进生物燃料有限责任公司 | 用于使用两相萃取发酵和可循环利用的提取剂组合物制备丁醇的方法 |
| WO2014047421A1 (en) | 2012-09-21 | 2014-03-27 | Butamax(Tm) Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| JP6407869B2 (ja) | 2012-09-26 | 2018-10-17 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトール酸レダクトイソメラーゼ活性を有するポリペプチド |
| WO2014052735A1 (en) | 2012-09-28 | 2014-04-03 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| CA2887574A1 (en) | 2012-10-11 | 2014-04-17 | Butamax Advanced Biofuels Llc | Processes and systems for the production of fermentation products |
| WO2014081848A1 (en) | 2012-11-20 | 2014-05-30 | Butamax Advanced Biofuels Llc | Butanol purification |
| CN104837799B (zh) | 2012-12-07 | 2020-07-31 | 艾菲纽技术公司 | 将可自生物质衍生得的脂肪醇催化转化制得有价值的烯烃或含氧化合物 |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| WO2014105840A1 (en) | 2012-12-31 | 2014-07-03 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| US20160002131A1 (en) | 2013-02-21 | 2016-01-07 | Butamax Advanced Biofuels Llc | Vapor recompression |
| WO2014159309A1 (en) | 2013-03-12 | 2014-10-02 | Butamax Advanced Biofuels Llc | Processes and systems for the production of alcohols |
| US9267158B2 (en) | 2013-03-14 | 2016-02-23 | Intrexon Corporation | Biological production of multi-carbon compounds from methane |
| AU2014244216A1 (en) | 2013-03-14 | 2015-09-24 | E.I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
| WO2014144210A2 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| WO2014144643A1 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Method for producing butanol using extractive fermentation |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
| WO2014151645A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Process for maximizing biomass growth and butanol yield by feedback control |
| BR112015020685A2 (pt) | 2013-03-15 | 2017-07-18 | Butamax Advanced Biofuels Llc | método para a recuperação do butanol, composição, métodos para a extração de álcool e de secagem |
| WO2015002913A1 (en) | 2013-07-03 | 2015-01-08 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
| EA033071B1 (ru) * | 2013-09-22 | 2019-08-30 | Ланцатек Нью Зилэнд Лимитед | Способ увеличения выхода продуктов из ацетолактата |
| WO2015065871A1 (en) | 2013-10-28 | 2015-05-07 | Danisco Us Inc. | Large scale genetically engineered active dry yeast |
| CN104195125B (zh) * | 2014-07-01 | 2017-01-11 | 中国科学院广州能源研究所 | 一种α-酮酸脱羧酶KIVD-LL及其编码基因和应用 |
| CA2957920A1 (en) | 2014-08-11 | 2016-02-18 | Butamax Advanced Biofuels Llc | Yeast preparations and methods of making the same |
| BR112017014234A2 (pt) | 2014-12-31 | 2018-03-06 | Ifp Energies Now | processo para a preparação olefinas pela desidratação de álcoois com menores efeitos colaterais compreendendo a adição de compostos contendo enxofre |
| WO2016107758A1 (en) | 2014-12-31 | 2016-07-07 | Total Research & Technology Feluy | Process for preparing olefins by dehydrating alcohols with less side effects comprising addition of organic acids |
| EP3162763A1 (en) | 2015-10-30 | 2017-05-03 | Total Research & Technology Feluy SA | Simultaneous dehydration and skeletal isomerisation of isobutanol on ti-containing zeolite catalysts |
| US11326193B1 (en) * | 2016-03-03 | 2022-05-10 | National Technology & Engineering Solutions Of Sandia, Llc | Enrichment of amino acids from biomass residuum |
| KR101960501B1 (ko) | 2017-09-15 | 2019-03-21 | 고려대학교 산학협력단 | Ｎａｄｈ 친화적인 신규 케톨산 리덕토아이소머라제 |
| CN111394325A (zh) * | 2019-07-05 | 2020-07-10 | 成都高界科技有限公司 | 一种耐热乙酰乳酸异构还原酶 |
| FR3115988A1 (fr) | 2020-11-06 | 2022-05-13 | Global Bioenergies | Composition de maquillage à base d’isododécane biosourcé et son procédé de préparation |
| FR3157389A1 (fr) | 2023-12-22 | 2025-06-27 | Axens | Procédé de production de bioalkylat ou d’essence biosourcée |
| WO2025226576A1 (en) | 2024-04-25 | 2025-10-30 | ExxonMobil Technology and Engineering Company | Processes for producing isobutylene and isobutylene-based polymers |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4865973A (en) | 1985-09-13 | 1989-09-12 | Queen's University At Kingston | Process for extractive fermentation |
| FR2696190B1 (fr) | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
| US6514733B1 (en) * | 1999-08-18 | 2003-02-04 | E. I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high titer |
| US20020061569A1 (en) | 2000-03-21 | 2002-05-23 | Robert Haselbeck | Identification of essential genes in prokaryotes |
| US6586229B1 (en) | 2000-06-01 | 2003-07-01 | North Carolina State University | Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium |
| US20040248250A1 (en) | 2001-07-02 | 2004-12-09 | Takahisa Nakai | Method for modifying enzyme and oxidoreductive variant |
| MXPA05009553A (es) | 2003-03-10 | 2006-03-17 | Broin And Associates Inc | Metodo para producir etanol utilizando almidon como materia prima. |
| SE526429C2 (sv) | 2003-10-24 | 2005-09-13 | Swedish Biofuels Ab | Metod för att framställa syreinnehållande föreningar utgående från biomassa |
| WO2006110900A2 (en) | 2005-04-12 | 2006-10-19 | E. I. Du Pont De Nemours And Company | Treatment of biomass to obtain ethanol |
| US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8956850B2 (en) | 2008-06-05 | 2015-02-17 | Butamax Advanced Biofuels Llc | Enhanced pyruvate to acetolactate conversion in yeast |
| NZ566406A (en) | 2005-10-26 | 2012-04-27 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| US7659104B2 (en) | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US7541173B2 (en) | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
| PL389665A1 (pl) * | 2007-02-09 | 2010-07-05 | The Regents of the University of CaliforniaThe Regents of the University of California | Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy |
| WO2008130995A2 (en) | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| EP2060632A1 (en) | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
| WO2009059254A2 (en) | 2007-10-31 | 2009-05-07 | Gevo, Inc | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
| DE602007011966D1 (de) | 2007-12-17 | 2011-02-24 | Suntory Holdings Ltd | Mutantes ilv5-gen und verwendung davon |
| EP2677028B1 (en) | 2007-12-20 | 2016-03-09 | Butamax (TM) Advanced Biofuels LLC | Ketol-acid reductoisomerase using NADH |
| US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
| US8372612B2 (en) | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| CN101952448A (zh) | 2007-12-23 | 2011-01-19 | 格沃股份有限公司 | 高产率产生异丁醇的酵母生物 |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
| WO2009143455A2 (en) | 2008-05-22 | 2009-11-26 | Microbia, Inc. | Engineering resistance to aliphatic alcohols |
| US8637281B2 (en) | 2008-09-29 | 2014-01-28 | Butamax(Tm) Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| EP2821484B1 (en) | 2008-09-29 | 2016-06-29 | Butamax Advanced Biofuels LLC | Identification and use of Bacterial [2Fe-2S] dihydroxy-acid dehydratases |
| CA2735948A1 (en) | 2008-09-29 | 2011-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| EP2342330A1 (en) | 2008-09-29 | 2011-07-13 | Butamax Advanced Biofuels Llc | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
| MX2011003313A (es) | 2008-09-29 | 2011-06-16 | Butamax Tm Advanced Biofuels | Actividad enzimatica de fe-s heterologa aumentada en levadura. |
| AU2009320163B2 (en) | 2008-10-27 | 2014-10-02 | Butamax(Tm) Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
| BRPI0921734A2 (pt) | 2008-10-31 | 2019-01-08 | California Inst Of Techn | micro-organismos criados geneticamente capazes de produzir compostos-alvo sob condições anaeróbicas |
| US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| US8828694B2 (en) | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
| US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
| US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
| US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
| US8795992B2 (en) | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
| US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
| US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
| EP2464736A4 (en) | 2009-08-12 | 2013-07-31 | Gevo Inc | PATIENT LOCALIZATION OF CYTOSOLIC ISOBUTANOL FOR THE MANUFACTURE OF ISOBUTANOL |
| JP5805094B2 (ja) | 2009-09-29 | 2015-11-04 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 高有効性のケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生産 |
| US9260708B2 (en) | 2009-09-29 | 2016-02-16 | Butamax Advanced Biofuels Llc | Yeast production host cells |
| JP2013505739A (ja) | 2009-09-29 | 2013-02-21 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 乳酸菌におけるアセト乳酸誘導生成物への改善されたフラックス |
| US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| GB2487889B (en) | 2009-11-24 | 2012-12-19 | Gevo Inc | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids |
| CN102762722B (zh) | 2009-12-29 | 2015-05-20 | 布特马斯先进生物燃料有限责任公司 | 用于发酵生产低级烷基醇的醇脱氢酶(adh) |
| KR20120099509A (ko) | 2009-12-29 | 2012-09-10 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 재조합 숙주 세포에서 육탄당 키나아제의 발현 |
| CN102869763A (zh) | 2010-02-12 | 2013-01-09 | 格沃股份有限公司 | 用于提高燃料、化学品和氨基酸产生的副产物蓄积减少的酵母微生物 |
| WO2011103300A2 (en) | 2010-02-17 | 2011-08-25 | Butamax(Tm) Advanced Biofuels Llc | Improving activity of fe-s cluster requiring proteins |
| AU2011268326B2 (en) | 2010-06-17 | 2015-02-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| EP2614138B1 (en) | 2010-09-07 | 2017-08-30 | Butamax (TM) Advanced Biofuels LLC | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| EP2689014B1 (en) | 2011-03-24 | 2019-04-24 | Butamax (TM) Advanced Biofuels LLC | Host cells and methods for production of isobutanol |
| US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
| BR112013032320A2 (pt) | 2011-06-17 | 2016-12-20 | Butamax Advanced Biofuels Llc | método e composição de produção de butanol, composição de butanol e isobutanol, método de cultivo de um micro-organismo produtor de butanol em material lignocelulósico e método para inibir o crescimento de micro-organismos que não produzem butanol em uma composição |
| US9238828B2 (en) | 2011-07-28 | 2016-01-19 | Butamax Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
| EP2798072A2 (en) | 2011-12-30 | 2014-11-05 | Butamax Advanced Biofuels LLC | Fermentative production of alcohols |
| AU2012362144A1 (en) | 2011-12-30 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
| JP2015510774A (ja) | 2012-03-23 | 2015-04-13 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ブタノール産生菌用培地の酢酸補給 |
| AU2013266727A1 (en) | 2012-05-11 | 2014-11-06 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| JP6407869B2 (ja) | 2012-09-26 | 2018-10-17 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | ケトール酸レダクトイソメラーゼ活性を有するポリペプチド |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
| AU2014244216A1 (en) | 2013-03-14 | 2015-09-24 | E.I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
-
2008
- 2008-04-16 WO PCT/US2008/060466 patent/WO2008130995A2/en not_active Ceased
- 2008-04-16 ES ES08745966T patent/ES2426070T3/es active Active
- 2008-04-16 US US12/103,844 patent/US7910342B2/en active Active
- 2008-04-16 AU AU2008242978A patent/AU2008242978B2/en not_active Ceased
- 2008-04-16 KR KR1020097023905A patent/KR101573775B1/ko not_active Expired - Fee Related
- 2008-04-16 CA CA2683898A patent/CA2683898C/en not_active Expired - Fee Related
- 2008-04-16 BR BRPI0808600A patent/BRPI0808600A2/pt not_active Application Discontinuation
- 2008-04-16 CN CN200880012258A patent/CN101680007A/zh active Pending
- 2008-04-16 JP JP2010504212A patent/JP5582576B2/ja not_active Expired - Fee Related
- 2008-04-16 EP EP08745966.5A patent/EP2134849B1/en active Active
- 2008-04-16 EP EP12180576A patent/EP2543721A1/en not_active Withdrawn
- 2008-04-16 MX MX2009011192A patent/MX2009011192A/es active IP Right Grant
- 2008-04-16 NZ NZ579780A patent/NZ579780A/en not_active IP Right Cessation
-
2009
- 2009-09-30 ZA ZA2009/06811A patent/ZA200906811B/en unknown
-
2011
- 2011-02-22 US US13/031,776 patent/US9284612B2/en active Active
-
2014
- 2014-05-26 JP JP2014107940A patent/JP5908026B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010524470A5 (enExample) | ||
| Tao et al. | The functional potential and active populations of the pit mud microbiome for the production of Chinese strong‐flavour liquor | |
| JP5582576B2 (ja) | 活性の高いケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生成 | |
| JP6862349B2 (ja) | 発酵経路を経由するフラックスの増大を示す組み換え微生物体 | |
| Kuntze et al. | 6‐Oxocyclohex‐1‐ene‐1‐carbonyl‐coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes | |
| Neveling et al. | Fructophilic Lactobacillus kunkeei and Lactobacillus brevis isolated from fresh flowers, bees and bee-hives | |
| US8945899B2 (en) | Ketol-acid reductoisomerase using NADH | |
| KR20110006698A (ko) | 박테리움 아크로모박터 자일로족시단스로부터의 부탄올 데하이드로게나제 효소 | |
| JP2009539407A (ja) | 溶媒耐性微生物および単離方法 | |
| JP2009513136A5 (enExample) | ||
| Moyer et al. | Effect of growth rate and starvation-survival on cellular DNA, RNA, and protein of a psychrophilic marine bacterium | |
| JP2011522541A (ja) | イソブタノールを生産するための欠失突然変異体 | |
| EP2710117A2 (en) | Recombinant microorganisms and methods of use thereof | |
| Valdes la Hens et al. | Prevalence of L actobacillus plantarum and O enococcus oeni during spontaneous malolactic fermentation in P atagonian red wines revealed by polymerase chain reaction‐denaturing gradient gel electrophoresis with two targeted genes | |
| JP2014506466A5 (enExample) | ||
| Miller et al. | Expression of the malolactic enzyme gene (mle) from Lactobacillus plantarum under winemaking conditions | |
| Watanabe et al. | A strategy to prevent the occurrence of Lactobacillus strains using lactate-tolerant yeast Candida glabrata in bioethanol production | |
| Landete et al. | PCR methods for the detection of biogenic amine-producing bacteria on wine | |
| Sootsuwan et al. | Thermotolerant Zymomonas mobilis: comparison of ethanol fermentation capability with that of an efficient type strain | |
| de Souza Liberal et al. | The yeast Dekkera bruxellensis genome contains two orthologs of the ARO10 gene encoding for phenylpyruvate decarboxylase | |
| CN105492606A (zh) | 2-脱氧青蟹肌糖还原酶 | |
| Min et al. | Changes in yeast and bacterial flora during fermentation and storage of Gugija-Liriope tuber Makgeolli using PCR-DGGE | |
| Krishnamoorthy et al. | Intergeneric protoplast fusion of yeast for high ethanol production from cheese industry waste–Whey | |
| KR102128031B1 (ko) | 메탄균과의 공동배양을 통해 적응 진화된 대장균 및 이를 이용하여 폐글리세롤로부터 숙신산을 제조하는 방법 | |
| CN114874963A (zh) | 一种生产羟基酪醇的重组需钠弧菌及其应用 |