MX2009011192A - Produccion fermentativa de isobutanol con el uso de enzimas reductoisomerasas con alta actividad acida y cetolica. - Google Patents

Produccion fermentativa de isobutanol con el uso de enzimas reductoisomerasas con alta actividad acida y cetolica.

Info

Publication number
MX2009011192A
MX2009011192A MX2009011192A MX2009011192A MX2009011192A MX 2009011192 A MX2009011192 A MX 2009011192A MX 2009011192 A MX2009011192 A MX 2009011192A MX 2009011192 A MX2009011192 A MX 2009011192A MX 2009011192 A MX2009011192 A MX 2009011192A
Authority
MX
Mexico
Prior art keywords
isobutanol
highly active
acid reductoisomerase
ketol
fermentive production
Prior art date
Application number
MX2009011192A
Other languages
English (en)
Spanish (es)
Inventor
Der-Ing Liao
Mark J Nelson
Michael G Bramucci
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of MX2009011192A publication Critical patent/MX2009011192A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2009011192A 2007-04-18 2008-04-16 Produccion fermentativa de isobutanol con el uso de enzimas reductoisomerasas con alta actividad acida y cetolica. MX2009011192A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91249107P 2007-04-18 2007-04-18
PCT/US2008/060466 WO2008130995A2 (en) 2007-04-18 2008-04-16 Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes

Publications (1)

Publication Number Publication Date
MX2009011192A true MX2009011192A (es) 2009-10-30

Family

ID=39872591

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011192A MX2009011192A (es) 2007-04-18 2008-04-16 Produccion fermentativa de isobutanol con el uso de enzimas reductoisomerasas con alta actividad acida y cetolica.

Country Status (13)

Country Link
US (2) US7910342B2 (enExample)
EP (2) EP2134849B1 (enExample)
JP (2) JP5582576B2 (enExample)
KR (1) KR101573775B1 (enExample)
CN (1) CN101680007A (enExample)
AU (1) AU2008242978B2 (enExample)
BR (1) BRPI0808600A2 (enExample)
CA (1) CA2683898C (enExample)
ES (1) ES2426070T3 (enExample)
MX (1) MX2009011192A (enExample)
NZ (1) NZ579780A (enExample)
WO (1) WO2008130995A2 (enExample)
ZA (1) ZA200906811B (enExample)

Families Citing this family (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
EP2118266A4 (en) * 2007-02-09 2010-05-19 Univ California BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS
TWI568847B (zh) 2007-03-16 2017-02-01 奇諾麥提卡公司 用於1,4-丁二醇及其前驅物之生物合成的組合物及方法
WO2008124523A1 (en) * 2007-04-04 2008-10-16 The Regents Of The University Of California Butanol production by recombinant microorganisms
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
JP2011500031A (ja) * 2007-10-12 2011-01-06 ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア イソプロパノールを生産するように操作された微生物
US8193402B2 (en) 2007-12-03 2012-06-05 Gevo, Inc. Renewable compositions
KR20100095004A (ko) 2007-12-03 2010-08-27 게보 인코포레이티드 재생 조성물
US8114641B2 (en) * 2007-12-10 2012-02-14 Synthetic Genomics, Inc. Methylbutanol as an advanced biofuel
SI2262901T1 (sl) 2008-03-05 2019-02-28 Genomatica, Inc. Primarni alkohol producirajoči organizmi
EP3351619A1 (en) 2008-03-27 2018-07-25 Genomatica, Inc. Microorganisms for the production of adipic acid and other compounds
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
EP2285973A4 (en) 2008-05-01 2012-04-25 Genomatica Inc PROCESS FOR PREPARING METHACRYLIC ACID
US8876924B2 (en) 2010-06-16 2014-11-04 Butamax Advanced Biofuels Llc Oxygenated butanol gasoline composition having good driveability performance
CA2735883C (en) 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
CN102186983A (zh) 2008-09-29 2011-09-14 布特马斯先进生物燃料有限责任公司 酵母中提高的异源Fe-S酶活性
CA2735690A1 (en) * 2008-09-29 2010-04-01 Dennis Flint Identification and use of bacterial [2fe-2s] dihydroxy-acid dehydratases
AU2009296218A1 (en) * 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria
BRPI0921734A2 (pt) * 2008-10-31 2019-01-08 California Inst Of Techn micro-organismos criados geneticamente capazes de produzir compostos-alvo sob condições anaeróbicas
US8828694B2 (en) * 2008-11-13 2014-09-09 Butamax Advanced Biofuels Llc Production of isobutanol in yeast mitochondria
US8465964B2 (en) 2008-11-13 2013-06-18 Butamax (TM) Advanced Biofules LLC Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis
AU2009324539B2 (en) * 2008-12-10 2015-10-01 Synthetic Genomics, Inc. Production of branched-chain alcohols by photosynthetic microorganisms
KR20110097951A (ko) 2008-12-16 2011-08-31 게노마티카 인코포레이티드 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법
US20120045809A1 (en) * 2008-12-23 2012-02-23 Gevo, Inc. Engineered Microorganisms for the Production of One or More Target Compounds
US8795992B2 (en) * 2008-12-29 2014-08-05 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving cell wall integrity pathway
US8557562B2 (en) * 2008-12-29 2013-10-15 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving filamentous growth response
US8455225B2 (en) * 2008-12-29 2013-06-04 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway
US8614085B2 (en) * 2009-02-27 2013-12-24 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving a multidrug efflux pump gene
JP2012523245A (ja) 2009-04-13 2012-10-04 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー 抽出発酵を用いてブタノールを生成するための方法
KR20200038334A (ko) 2009-05-07 2020-04-10 게노마티카 인코포레이티드 아디페이트, 헥사메틸렌디아민 및 6-아미노카프로산의 생합성을 위한 미생물 및 방법
US8129169B2 (en) 2009-06-04 2012-03-06 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
KR20180042467A (ko) 2009-06-04 2018-04-25 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
CA2770842A1 (en) * 2009-08-12 2011-02-17 Gevo, Inc. Cytosolic isobutanol pathway localization for the production of isobutanol
BR112012006939A2 (pt) * 2009-09-29 2015-09-08 Butamax Tm Advanced Biofuels célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides
EP2483400A1 (en) * 2009-09-29 2012-08-08 Butamax(tm) Advanced Biofuels LLC Improved flux to acetolactate-derived products in lactic acid bacteria
CA2775892A1 (en) * 2009-09-29 2011-04-07 Butamax(Tm) Advanced Biofuels Llc Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes
US20110195505A1 (en) * 2009-10-08 2011-08-11 Butamax(Tm) Advanced Biofuels Llc Bacterial strains for butanol production
WO2011047101A1 (en) 2009-10-13 2011-04-21 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
NZ599414A (en) * 2009-11-23 2014-08-29 Butamax Tm Advanced Biofuels Method for producing butanol using extractive fermentation with electrolyte addition
CA2779460A1 (en) * 2009-11-23 2011-05-26 Butamax(Tm) Advanced Biofuels Llc Method for producing butanol using extractive fermentation with osmolyte addition
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
US20110137088A1 (en) * 2009-12-03 2011-06-09 Bp Corporation North America Inc. Methods and Apparatuses for Producing Renewable Materials From Inhibiting Compounds
MX2012007583A (es) 2009-12-29 2012-07-30 Butamax Tm Advanced Biofuels Alcohol deshidrogenasas (adh) utiles para la produccion fermentativa de alcoholes alquilicos de cadena corta.
US8637289B2 (en) 2009-12-29 2014-01-28 Butamax(Tm) Advanced Biofuels Llc Expression of hexose kinase in recombinant host cells
BR112012016883A2 (pt) 2010-01-08 2018-06-05 Gevo Inc metodos integrados de preparar produsot quimicos renovaveis
US8530221B2 (en) 2010-01-14 2013-09-10 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
US8574406B2 (en) * 2010-02-09 2013-11-05 Butamax Advanced Biofuels Llc Process to remove product alcohol from a fermentation by vaporization under vacuum
CN102782119B (zh) 2010-02-17 2016-03-16 布特马斯先进生物燃料有限责任公司 改善需Fe-S簇蛋白质的活性
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
ES2604134T3 (es) 2010-03-15 2017-03-03 Total Research & Technology Feluy Producción de propileno mediante deshidratación e isomerización del esqueleto simultáneas del isobutanol sobre catalizadores ácidos seguidas de metátesis
EP2374780A1 (en) 2010-04-09 2011-10-12 Total Petrochemicals Research Feluy Production of propylene via simultaneous dehydration and skeletal isomerisation of isobutanol on acid catalysts followed by metathesis
MY158968A (en) 2010-03-15 2016-11-30 Total Res & Technology Feluy Simultaneous dehydration and skeletal isomerisation of isobutanol on acid catalysts
EP2374781A1 (en) 2010-04-09 2011-10-12 Total Petrochemicals Research Feluy Simultaneous dehydration and skeletal isomerisation of isobutanol on acid catalysts
US8373012B2 (en) 2010-05-07 2013-02-12 Gevo, Inc. Renewable jet fuel blendstock from isobutanol
CA2801062C (en) 2010-06-16 2019-04-02 Butamax(Tm) Advanced Biofuels Llc Oxygenated butanol gasoline composition having good driveability performance
AU2011268326B2 (en) 2010-06-17 2015-02-05 Butamax(Tm) Advanced Biofuels Llc Yeast production culture for the production of butanol
CN105950673A (zh) 2010-06-18 2016-09-21 布特马斯先进生物燃料有限责任公司 在提取发酵中用于醇移除的来源于油的提取溶剂
US9040263B2 (en) 2010-07-28 2015-05-26 Butamax Advanced Biofuels Llc Production of alcohol esters and in situ product removal during alcohol fermentation
US9012190B2 (en) 2011-06-15 2015-04-21 Butamax Advanced Biofuels Llc Use of thiamine and nicotine adenine dinucleotide for butanol production
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
KR20130032897A (ko) 2010-06-18 2013-04-02 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 알코올 발효 시의 알코올 에스테르의 생성 및 원위치에서의 생성물 제거
EP2601157B1 (en) 2010-08-03 2019-03-06 Total Research & Technology Feluy Combined process to make olefins from isobutanol
CN103153919B (zh) 2010-08-03 2015-05-13 道达尔研究技术弗吕公司 由异丁醇制造烯烃的方法
WO2012016788A1 (en) 2010-08-03 2012-02-09 Total Petrochemicals Research Feluy Process to make olefins from methanol and isobutanol
BR112013002359B1 (pt) 2010-08-03 2019-10-08 Total Research & Technology Feluy Processo para produzir olefinas a partir de isobutanol
WO2012027642A1 (en) * 2010-08-27 2012-03-01 Gevo, Inc. Balanced four-step pathways to renewable butanols
NZ707800A (en) 2010-09-07 2016-09-30 Butamax Tm Advanced Biofuels Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
EP2619159A1 (en) 2010-09-24 2013-07-31 Total Research & Technology Feluy Production of isoprene from iso-butanol
WO2012071121A1 (en) * 2010-11-24 2012-05-31 Gevo, Inc. Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
FR2969147B1 (fr) 2010-12-21 2013-01-04 Total Raffinage Marketing Production d'additifs pour carburant par deshydratation et isomerisation squelettique simultanee d'isobutanol sur des catalyseurs acides suivies par une etherification
US20130040340A1 (en) 2011-02-07 2013-02-14 E. I. Du Pont De Nemours And Company Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms
US8765425B2 (en) 2011-03-23 2014-07-01 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US8759044B2 (en) 2011-03-23 2014-06-24 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
EP2689014B1 (en) 2011-03-24 2019-04-24 Butamax (TM) Advanced Biofuels LLC Host cells and methods for production of isobutanol
EP2699618A4 (en) 2011-04-19 2014-12-17 Gevo Inc VARIATIONS OF A PRINS REACTION FOR THE PREPARATION OF 2,5-DIMETHYLHEXADIENE FROM ISOBUTANOL
WO2013048599A2 (en) * 2011-06-16 2013-04-04 Gevo, Inc. Ketol-acid reductoisomerases with improved performance properties
CA2837722A1 (en) 2011-06-17 2012-12-20 Butamax Advanced Biofuels Llc Co-products from biofuel production processes and methods of making
CN105473726B (zh) 2011-07-28 2021-03-12 布特马斯先进生物燃料有限责任公司 酮异戊酸脱羧酶及其使用方法
AU2012347687A1 (en) 2011-12-09 2014-05-29 Butamax Advanced Biofuels Llc Process to remove product alcohols from fermentation broth by multistep flash evaporation
US9181566B2 (en) 2011-12-30 2015-11-10 Butamax Advanced Biofuels Llc Genetic switches for butanol production
US9909148B2 (en) 2011-12-30 2018-03-06 Butamax Advanced Biofuels Llc Fermentative production of alcohols
KR20140146616A (ko) 2012-03-23 2014-12-26 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 부타놀로겐용 배지의 아세테이트 보충물
MX2014013446A (es) 2012-05-11 2014-12-08 Butamax Advanced Biofuels Llc Enzimas de cetol-acido reductoisomerasa y metodos de uso.
SI2855687T1 (sl) 2012-06-04 2020-09-30 Genomatica, Inc. Mikroorganizmi in metode za proizvodnjo 4-hidroksibutirat, 1,4-butandiola in sorodne spojine
US20140024064A1 (en) 2012-07-23 2014-01-23 Butamax(Tm) Advanced Biofuels Llc Processes and systems for the production of fermentative alcohols
AU2013295626B2 (en) 2012-07-26 2018-02-01 Butamax Advanced Biofuels Llc Butanol purification
US10233467B2 (en) 2012-08-17 2019-03-19 Easel Biotechnologies, Llc Two-stage production of higher alcohols
BR112015003701A2 (pt) 2012-08-22 2017-12-12 Butamax Advanced Biofuels Llc células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição
CA2883627A1 (en) 2012-09-12 2014-03-20 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
WO2014047421A1 (en) 2012-09-21 2014-03-27 Butamax(Tm) Advanced Biofuels Llc Production of renewable hydrocarbon compositions
US9249076B2 (en) 2012-09-21 2016-02-02 Butamax Advanced Biofuels Llc Recyclable extractant compositions
AU2013323427A1 (en) 2012-09-26 2015-03-05 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
EP2900825A1 (en) 2012-09-28 2015-08-05 Butamax Advanced Biofuels LLC Production of fermentation products
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
EP2906706B1 (en) 2012-10-11 2020-02-26 Butamax Advanced Biofuels LLC Processes and systems for the production of fermentation products
WO2014081848A1 (en) 2012-11-20 2014-05-30 Butamax Advanced Biofuels Llc Butanol purification
US10300464B2 (en) 2012-12-07 2019-05-28 Evernu Technology, Llc Catalytic conversion of bio-mass derivable aliphatic alcohols to valuable alkenes or oxygenates
WO2014106107A2 (en) 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
WO2014105840A1 (en) 2012-12-31 2014-07-03 Butamax Advanced Biofuels Llc Fermentative production of alcohols
US20160002131A1 (en) 2013-02-21 2016-01-07 Butamax Advanced Biofuels Llc Vapor recompression
WO2014159309A1 (en) 2013-03-12 2014-10-02 Butamax Advanced Biofuels Llc Processes and systems for the production of alcohols
ES2735024T3 (es) 2013-03-14 2019-12-13 Du Pont Glicerol-3-fosfato deshidrogenasa para la producción de butanol
US9267158B2 (en) 2013-03-14 2016-02-23 Intrexon Corporation Biological production of multi-carbon compounds from methane
WO2014144643A1 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Method for producing butanol using extractive fermentation
WO2014144210A2 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
CA2901374A1 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Method for production of butanol using extractive fermentation
WO2014151645A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Process for maximizing biomass growth and butanol yield by feedback control
US9580705B2 (en) 2013-03-15 2017-02-28 Butamax Advanced Biofuels Llc DHAD variants and methods of screening
WO2015002913A1 (en) 2013-07-03 2015-01-08 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
DK3047028T5 (da) * 2013-09-22 2024-10-14 Lanzatech Nz Inc Fermenteringsfremgangsmåde
EP3063263A1 (en) 2013-10-28 2016-09-07 Danisco US Inc. Large scale genetically engineered active dry yeast
CN104195125B (zh) * 2014-07-01 2017-01-11 中国科学院广州能源研究所 一种α-酮酸脱羧酶KIVD-LL及其编码基因和应用
CA2957920A1 (en) 2014-08-11 2016-02-18 Butamax Advanced Biofuels Llc Yeast preparations and methods of making the same
WO2016107759A1 (en) 2014-12-31 2016-07-07 Total Research & Technology Feluy Process for preparing olefins by dehydrating alcohols with less side effects comprising addition of sulfur containing compounds
WO2016107758A1 (en) 2014-12-31 2016-07-07 Total Research & Technology Feluy Process for preparing olefins by dehydrating alcohols with less side effects comprising addition of organic acids
EP3162763A1 (en) 2015-10-30 2017-05-03 Total Research & Technology Feluy SA Simultaneous dehydration and skeletal isomerisation of isobutanol on ti-containing zeolite catalysts
US11326193B1 (en) 2016-03-03 2022-05-10 National Technology & Engineering Solutions Of Sandia, Llc Enrichment of amino acids from biomass residuum
KR101960501B1 (ko) 2017-09-15 2019-03-21 고려대학교 산학협력단 Nadh 친화적인 신규 케톨산 리덕토아이소머라제
CN111394325A (zh) * 2019-07-05 2020-07-10 成都高界科技有限公司 一种耐热乙酰乳酸异构还原酶
FR3115988A1 (fr) 2020-11-06 2022-05-13 Global Bioenergies Composition de maquillage à base d’isododécane biosourcé et son procédé de préparation
KR20250041206A (ko) * 2023-09-18 2025-03-25 엘지디스플레이 주식회사 이방성 도전필름 및 이를 포함하는 표시장치
FR3157389A1 (fr) 2023-12-22 2025-06-27 Axens Procédé de production de bioalkylat ou d’essence biosourcée
WO2025226576A1 (en) 2024-04-25 2025-10-30 ExxonMobil Technology and Engineering Company Processes for producing isobutylene and isobutylene-based polymers

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4865973A (en) 1985-09-13 1989-09-12 Queen's University At Kingston Process for extractive fermentation
FR2696190B1 (fr) 1992-09-25 1994-12-09 Agronomique Inst Nat Rech Acide nucléique codant pour une alpha-acétolactate synthase et ses applications.
PT1204755E (pt) * 1999-08-18 2006-11-30 Du Pont Processo para a produção biológica de 1, 3-propanodiol
EP1268774A2 (en) 2000-03-21 2003-01-02 Elitra Pharmaceuticals, Inc. Identification of essential genes in prokaryotes
US6586229B1 (en) 2000-06-01 2003-07-01 North Carolina State University Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium
KR20040014655A (ko) 2001-07-02 2004-02-14 가네가후치 가가쿠 고교 가부시키가이샤 효소 개변 방법 및 산화 환원 효소 변이체
MXPA05009553A (es) 2003-03-10 2006-03-17 Broin And Associates Inc Metodo para producir etanol utilizando almidon como materia prima.
SE526429C2 (sv) 2003-10-24 2005-09-13 Swedish Biofuels Ab Metod för att framställa syreinnehållande föreningar utgående från biomassa
BRPI0612944B1 (pt) 2005-04-12 2017-11-28 E.I.Du Pont De Nemours And Company Method of production of target substance
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
EP1948814B1 (en) 2005-10-26 2018-11-21 Butamax (TM) Advanced Biofuels LLC Fermentive production of four carbon alcohols
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8956850B2 (en) 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8962298B2 (en) 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
US7659104B2 (en) * 2006-05-05 2010-02-09 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
US7541173B2 (en) 2006-06-15 2009-06-02 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
US8017364B2 (en) 2006-12-12 2011-09-13 Butamax(Tm) Advanced Biofuels Llc Solvent tolerant microorganisms
EP2118266A4 (en) * 2007-02-09 2010-05-19 Univ California BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
EP2060632A1 (en) 2007-10-29 2009-05-20 Technische Universität Berlin Method of modifying a yeast cell for the production of ethanol
EP2215243A2 (en) 2007-10-31 2010-08-11 GEVO, Inc. Methods for the economical production of biofuel precursor that is also a biofuel from biomass
ATE495260T1 (de) 2007-12-17 2011-01-15 Suntory Holdings Ltd Mutantes ilv5-gen und verwendung davon
ES2575413T3 (es) 2007-12-20 2016-06-28 Butamax (Tm) Advanced Biofuels Llc Cetol-ácido reductoisomerasa que utiliza NADH
US8372612B2 (en) 2007-12-21 2013-02-12 Butamax(Tm) Advanced Biofuels Llc Production of four carbon alcohols using improved strain
US8518678B2 (en) 2007-12-21 2013-08-27 Butamax(Tm) Advanced Biofuels Llc Strain comprising increased expression of a CFA coding region for butanol production
CN101952448A (zh) 2007-12-23 2011-01-19 格沃股份有限公司 高产率产生异丁醇的酵母生物
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
US8389252B2 (en) 2008-05-12 2013-03-05 Butamax(Tm) Advanced Biofuels Llc Yeast strain for production of four carbon alcohols
US8906666B2 (en) 2008-05-22 2014-12-09 Butamax Advanced Biofuels Llc Engineering resistance to aliphatic alcohols
CA2735690A1 (en) 2008-09-29 2010-04-01 Dennis Flint Identification and use of bacterial [2fe-2s] dihydroxy-acid dehydratases
AU2009296218A1 (en) 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria
CA2735948A1 (en) 2008-09-29 2011-04-01 Butamaxtm Advanced Biofuels Llc Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
BRPI0913680A2 (pt) 2008-09-29 2019-09-24 Butamax Advanced Biofuels Llc "célula bacteriana ácido-láctica, método para aumentar a atividade de um polipeptídeo dihidroxi-ácido desidratase heterólogo em uma célula bacteriana ácido-láctica e método de produção de insobutanol"
CN102186983A (zh) 2008-09-29 2011-09-14 布特马斯先进生物燃料有限责任公司 酵母中提高的异源Fe-S酶活性
WO2010062597A1 (en) 2008-10-27 2010-06-03 Butamax™ Advanced Biofuels LLC Carbon pathway optimized production hosts for the production of isobutanol
BRPI0921734A2 (pt) 2008-10-31 2019-01-08 California Inst Of Techn micro-organismos criados geneticamente capazes de produzir compostos-alvo sob condições anaeróbicas
US8465964B2 (en) 2008-11-13 2013-06-18 Butamax (TM) Advanced Biofules LLC Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis
US8828694B2 (en) 2008-11-13 2014-09-09 Butamax Advanced Biofuels Llc Production of isobutanol in yeast mitochondria
US8652823B2 (en) 2008-12-03 2014-02-18 Butamax(Tm) Advanced Biofuels Llc Strain for butanol production with increased membrane unsaturated trans fatty acids
US8795992B2 (en) 2008-12-29 2014-08-05 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving cell wall integrity pathway
US8455225B2 (en) 2008-12-29 2013-06-04 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway
US8557562B2 (en) 2008-12-29 2013-10-15 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving filamentous growth response
US8614085B2 (en) 2009-02-27 2013-12-24 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving a multidrug efflux pump gene
US20120058541A1 (en) 2009-05-22 2012-03-08 Butamax(Tm) Advanced Biofuels Llc Engineering resistance to aliphatic alcohols
CA2770842A1 (en) 2009-08-12 2011-02-17 Gevo, Inc. Cytosolic isobutanol pathway localization for the production of isobutanol
CA2775892A1 (en) 2009-09-29 2011-04-07 Butamax(Tm) Advanced Biofuels Llc Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes
BR112012006939A2 (pt) 2009-09-29 2015-09-08 Butamax Tm Advanced Biofuels célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides
EP2483400A1 (en) 2009-09-29 2012-08-08 Butamax(tm) Advanced Biofuels LLC Improved flux to acetolactate-derived products in lactic acid bacteria
US20110195505A1 (en) 2009-10-08 2011-08-11 Butamax(Tm) Advanced Biofuels Llc Bacterial strains for butanol production
GB2487889B (en) 2009-11-24 2012-12-19 Gevo Inc Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
MX2012007583A (es) 2009-12-29 2012-07-30 Butamax Tm Advanced Biofuels Alcohol deshidrogenasas (adh) utiles para la produccion fermentativa de alcoholes alquilicos de cadena corta.
US8637289B2 (en) 2009-12-29 2014-01-28 Butamax(Tm) Advanced Biofuels Llc Expression of hexose kinase in recombinant host cells
WO2011142865A2 (en) 2010-02-12 2011-11-17 Gevo, Inc. Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids
CN102782119B (zh) 2010-02-17 2016-03-16 布特马斯先进生物燃料有限责任公司 改善需Fe-S簇蛋白质的活性
AU2011268326B2 (en) 2010-06-17 2015-02-05 Butamax(Tm) Advanced Biofuels Llc Yeast production culture for the production of butanol
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
NZ707800A (en) 2010-09-07 2016-09-30 Butamax Tm Advanced Biofuels Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
EP2689014B1 (en) 2011-03-24 2019-04-24 Butamax (TM) Advanced Biofuels LLC Host cells and methods for production of isobutanol
US20120258873A1 (en) 2011-04-06 2012-10-11 Butamax(Tm) Advanced Biofuels Llc Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production
JP2014522634A (ja) 2011-06-17 2014-09-08 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー イソブタノール発酵の原料としてのリグノセルロース加水分解物
CN105473726B (zh) 2011-07-28 2021-03-12 布特马斯先进生物燃料有限责任公司 酮异戊酸脱羧酶及其使用方法
US9181566B2 (en) 2011-12-30 2015-11-10 Butamax Advanced Biofuels Llc Genetic switches for butanol production
US9909148B2 (en) 2011-12-30 2018-03-06 Butamax Advanced Biofuels Llc Fermentative production of alcohols
KR20140146616A (ko) 2012-03-23 2014-12-26 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 부타놀로겐용 배지의 아세테이트 보충물
MX2014013446A (es) 2012-05-11 2014-12-08 Butamax Advanced Biofuels Llc Enzimas de cetol-acido reductoisomerasa y metodos de uso.
AU2013323427A1 (en) 2012-09-26 2015-03-05 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
US20140186911A1 (en) 2012-12-28 2014-07-03 Butamax Advanced Biofuels Llc Recombinant host cells and methods for producing butanol
WO2014106107A2 (en) 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
ES2735024T3 (es) 2013-03-14 2019-12-13 Du Pont Glicerol-3-fosfato deshidrogenasa para la producción de butanol
US9580705B2 (en) 2013-03-15 2017-02-28 Butamax Advanced Biofuels Llc DHAD variants and methods of screening

Also Published As

Publication number Publication date
KR20100016602A (ko) 2010-02-12
KR101573775B1 (ko) 2015-12-04
WO2008130995A2 (en) 2008-10-30
US20110250610A1 (en) 2011-10-13
JP5582576B2 (ja) 2014-09-03
CA2683898A1 (en) 2008-10-30
EP2134849A2 (en) 2009-12-23
AU2008242978B2 (en) 2014-09-18
EP2134849B1 (en) 2013-07-10
ES2426070T3 (es) 2013-10-21
JP2014176386A (ja) 2014-09-25
US20080261230A1 (en) 2008-10-23
JP5908026B2 (ja) 2016-04-26
US7910342B2 (en) 2011-03-22
AU2008242978A1 (en) 2008-10-30
WO2008130995A3 (en) 2009-02-05
BRPI0808600A2 (pt) 2018-12-26
JP2010524470A (ja) 2010-07-22
EP2543721A1 (en) 2013-01-09
CA2683898C (en) 2016-02-02
ZA200906811B (en) 2010-12-29
NZ579780A (en) 2012-07-27
CN101680007A (zh) 2010-03-24
US9284612B2 (en) 2016-03-15

Similar Documents

Publication Publication Date Title
WO2008130995A3 (en) Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
WO2011079048A3 (en) Methods for improving the efficiency of simultaneous saccharification and fermentation reactions
MX2010004014A (es) Mezclas enzimaticas para fermentacion.
PL2586313T3 (pl) Sposób fermentacji przy użyciu komórek drożdży mających zaburzony szlak od fosforanu dihydroksyacetonu do glicerolu
WO2006110901A3 (en) Treatment of biomass to obtain fermentable sugars
WO2008038075A3 (en) Microbial liquid cultures having high stability and fermentative activity
WO2011133902A3 (en) Cell culture medium comprising small peptides
WO2007130518A3 (en) Fermentive production of four carbon alcohols
NZ593469A (en) Yeast expressing cellulases for simultaneous saccharification and fermentation using cellulose
UA103363C2 (ru) Способ ферментативного производства четырехатомных спиртов
WO2011142865A3 (en) Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids
WO2008153815A3 (en) Variants of an alpha-amylase with improved production levels in fermentation processes
CL2011003314A1 (es) Proceso y sistema para producir bioproducto que comprende fermentar continuamente un microorganismo inmovilizado sobre soporte en biorreactor usando materia prima hidrolizada que comprende carbohidratos, que sirven como materia prima para la fermentacion, donde la materia prima se alimenta continuamente durante la fermentacion.
WO2012074818A3 (en) Compositions and methods for 3-hydroxypropionic acid production
EP2329033A4 (en) MATERIAL AND METHOD FOR CONVERTING BIOMASS IN BIOFUEL
MY170602A (en) Process for fractionation of biomass
WO2010075529A3 (en) Heterologous biomass degrading enzyme expression in thermoanaerobacterium saccharolyticum
MX2010010144A (es) Composiciones enriquecidas con hemicelulasa para incrementar la hidrolisis de biomasa.
SI1828065T1 (sl) Postopek za povečano produkcijo bioplina v termofilnih, anaerobnih fermentorjih
WO2012027282A3 (en) Recombinant lignocellulose degradation enzymes for the production of soluble sugars from cellulosic biomass
WO2013039776A8 (en) Methods of hydrolyzing and fermenting cellulosic material
WO2009134964A3 (en) Enhanced fermentation process using molasses
WO2012068047A3 (en) Process for producing a fermentation product in the presence of an amino acid oxidase, an arginase and/or an asparaginase
WO2009158627A3 (en) Cellulosic protein expression in yeast
HUE050997T2 (hu) Keményítõ- és xilánbontó enzimek expresszálásával keményítõ és xilán alkoholos fermentációjára képes hõtûrõ Hansenula polymorpha élesztõtörzsek kifejlesztése

Legal Events

Date Code Title Description
FG Grant or registration