|
GB921315A
(en)
|
1958-03-31 |
1963-03-20 |
Wellcome Found |
The manufacture of 8-aminoalkylamino quinoline derivatives
|
|
US3956287A
(en)
*
|
1973-11-07 |
1976-05-11 |
Richardson-Merrell Inc. |
7-[(2-Oxo-1-pyridinyl)acylamino]cephalosporin derivatives
|
|
JPS62232555A
(ja)
|
1986-04-02 |
1987-10-13 |
Unitika Ltd |
酵素センサ
|
|
US4959212A
(en)
|
1988-06-22 |
1990-09-25 |
Alexandra Stancesco |
Oxidizing-energizing composition and method for the treatment of diabetes
|
|
US5239080A
(en)
|
1989-02-08 |
1993-08-24 |
Takeda Chemical Industries, Ltd. |
Oxazole compounds and their use as antidiabetic and bone-reduction inhibitory agents
|
|
DE4211474A1
(de)
*
|
1992-04-06 |
1993-10-07 |
Merck Patent Gmbh |
Imidazopyridine
|
|
US5541060A
(en)
|
1992-04-22 |
1996-07-30 |
Arch Development Corporation |
Detection of glucokinase-linked early-onset non-insulin-dependent diabetes mellitus
|
|
EP0616036B1
(en)
|
1993-03-17 |
1999-07-28 |
Unitika Ltd. |
Process for producing fructose 2,6-disphosphate and purification process thereof
|
|
JP3203108B2
(ja)
|
1993-08-26 |
2001-08-27 |
協和メデックス株式会社 |
グルコース−6−リン酸デヒドロゲナーゼの安定化方法
|
|
DE4341665A1
(de)
|
1993-12-07 |
1995-06-08 |
Basf Ag |
Bicyclen-Derivate, ihre Herstellung und Verwendung
|
|
US6486380B1
(en)
|
1993-12-17 |
2002-11-26 |
University Of North Dakota Medical Education Research Foundation |
Pancreatic β cell hexokinase transgene
|
|
US7041503B2
(en)
|
1995-05-02 |
2006-05-09 |
The United States Of America As Represented By The Department Of Health And Human Services |
Modified myelin basic protein molecules
|
|
US5854067A
(en)
|
1996-01-19 |
1998-12-29 |
Board Of Regents, The University Of Texas System |
Hexokinase inhibitors
|
|
GB9618934D0
(en)
|
1996-09-11 |
1996-10-23 |
Univ London |
Inositol phosphoglycans for therapeutic use in the treatment of diabetes and obesity
|
|
US6642360B2
(en)
|
1997-12-03 |
2003-11-04 |
Genentech, Inc. |
Secreted polypeptides that stimulate release of proteoglycans from cartilage
|
|
US20020032330A1
(en)
|
1996-12-24 |
2002-03-14 |
Yutaka Nomura |
Propionic acid derivatives
|
|
FR2758326B1
(fr)
*
|
1997-01-16 |
1999-02-12 |
Synthelabo |
Derives de pyridone, leur prepaparation et leur utilisation comme intermediaires de synthese
|
|
US20020137890A1
(en)
|
1997-03-31 |
2002-09-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
ZA988460B
(en)
|
1997-09-17 |
1999-03-19 |
Genentech Inc |
Polypeptides and nucleic acids encoding the same
|
|
US7378507B2
(en)
|
1997-09-18 |
2008-05-27 |
Genentech, Inc. |
PRO217 polypeptides
|
|
US6391311B1
(en)
|
1998-03-17 |
2002-05-21 |
Genentech, Inc. |
Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1
|
|
US6894148B2
(en)
|
1997-11-12 |
2005-05-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030129691A1
(en)
|
1998-02-09 |
2003-07-10 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20040048332A1
(en)
|
1998-04-29 |
2004-03-11 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7339033B2
(en)
|
1998-06-26 |
2008-03-04 |
Genentech, Inc. |
Pro1481
|
|
US20030073188A1
(en)
|
1998-07-07 |
2003-04-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2001088088A2
(en)
|
2000-05-18 |
2001-11-22 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US6242666B1
(en)
|
1998-12-16 |
2001-06-05 |
The Scripps Research Institute |
Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
|
|
WO2000057921A2
(en)
|
1999-02-19 |
2000-10-05 |
During Matthew J |
Peroral gene therapy of diabetes and obesity
|
|
US7109292B2
(en)
|
1999-03-08 |
2006-09-19 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
CA2361840A1
(en)
|
1999-03-08 |
2000-09-14 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US6610846B1
(en)
|
1999-03-29 |
2003-08-26 |
Hoffman-La Roche Inc. |
Heteroaromatic glucokinase activators
|
|
RU2242469C2
(ru)
|
1999-03-29 |
2004-12-20 |
Ф.Хоффманн-Ля Рош Аг |
Активаторы глюкокиназы
|
|
BR0009486B1
(pt)
|
1999-03-29 |
2011-03-09 |
|
composto que compreende uma amida, composição farmacêutica que compreende esse composto, seu uso e processo para a preparação do mesmo.
|
|
US6320050B1
(en)
|
1999-03-29 |
2001-11-20 |
Hoffmann-La Roche Inc. |
Heteroaromatic glucokinase activators
|
|
US6967019B2
(en)
|
1999-04-06 |
2005-11-22 |
The Regents Of The University Of California |
Production of pancreatic islet cells and delivery of insulin
|
|
US8193330B2
(en)
|
1999-04-06 |
2012-06-05 |
The Regents Of The University Of California |
Polynucleotides comprising Neurogenin3 promoter and bHLH encoding domains
|
|
US6774120B1
(en)
|
1999-06-01 |
2004-08-10 |
Sarah Ferber |
Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
|
|
JP4447705B2
(ja)
|
1999-10-20 |
2010-04-07 |
独立行政法人科学技術振興機構 |
糖尿病発症モデル哺乳動物
|
|
US20040072739A1
(en)
|
1999-11-10 |
2004-04-15 |
Anderson Christen M. |
Compositions and methods for regulating endogenous inhibitor of ATP synthase, including treatment for diabetes
|
|
AR026748A1
(es)
*
|
1999-12-08 |
2003-02-26 |
Vertex Pharma |
Un compuesto inhibidor de caspasas, una composicion farmaceutica que lo comprende, un metodo para la sintesis del mismo y un compuesto intermediario paradicha sintesis
|
|
US6353111B1
(en)
|
1999-12-15 |
2002-03-05 |
Hoffmann-La Roche Inc. |
Trans olefinic glucokinase activators
|
|
US6608038B2
(en)
|
2000-03-15 |
2003-08-19 |
Novartis Ag |
Methods and compositions for treatment of diabetes and related conditions via gene therapy
|
|
US6716582B2
(en)
|
2000-04-14 |
2004-04-06 |
E. I. Du Pont De Nemours And Company |
Cellular arrays for the identification of altered gene expression
|
|
WO2001098454A2
(en)
|
2000-04-25 |
2001-12-27 |
German Human Genome Project |
Human dna sequences
|
|
US6388071B2
(en)
|
2000-05-03 |
2002-05-14 |
Hoffmann-La Roche Inc. |
Alkynyl phenyl heteroaromatic glucokinase activators
|
|
JP3842131B2
(ja)
|
2000-05-03 |
2006-11-08 |
エフ.ホフマン−ラ ロシュ アーゲー |
ヒダントイン含有グルコキナーゼ活性化物質
|
|
US6489485B2
(en)
|
2000-05-08 |
2002-12-03 |
Hoffmann-La Roche Inc. |
Para-amine substituted phenylamide glucokinase activators
|
|
ATE398611T1
(de)
|
2000-05-08 |
2008-07-15 |
Hoffmann La Roche |
Para-amin substituierte phenylamid glukokinase activatoren
|
|
EP1282611B1
(en)
|
2000-05-08 |
2004-10-20 |
F. Hoffmann-La Roche Ag |
Substituted phenylacetamides and their use as glucokinase activators
|
|
AU2001263360A1
(en)
|
2000-05-19 |
2001-12-03 |
Millennium Pharmaceuticals, Inc. |
50365, a hexokinase family member and uses thereof
|
|
WO2001092523A2
(en)
|
2000-05-30 |
2001-12-06 |
Curagen Corporation |
Human polynucleotides and polypeptides encoded thereby
|
|
AU2001265231B2
(en)
|
2000-05-31 |
2006-07-06 |
Promega Corporation |
Assay for kinases and phosphatases
|
|
US20030149237A1
(en)
|
2000-06-27 |
2003-08-07 |
Corine Vernet |
Novel polynucleotides and polypeptides encoded thereby
|
|
WO2002006339A2
(en)
|
2000-07-03 |
2002-01-24 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
WO2002008277A2
(en)
|
2000-07-19 |
2002-01-31 |
Eli Lilly And Company |
Nucleic acids, vectors, host cells, polypeptides, and uses thereof
|
|
EP1354040A2
(en)
|
2000-07-20 |
2003-10-22 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
DE60111534T2
(de)
|
2000-07-20 |
2006-05-11 |
F. Hoffmann-La Roche Ag |
Alpha-acyl- und alpha-heteroatom-substituierte benzenacetamide verwendbar als glucokinase-aktivatoren
|
|
US7371817B2
(en)
|
2000-07-25 |
2008-05-13 |
Genentech, Inc. |
PRO9783 polypeptides
|
|
US20030100709A1
(en)
|
2000-07-25 |
2003-05-29 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20040044179A1
(en)
|
2000-07-25 |
2004-03-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030212255A1
(en)
|
2000-07-26 |
2003-11-13 |
Muralidhara Padigaru |
Novel proteins and nucleic acids encoding same
|
|
WO2002014358A2
(en)
|
2000-08-11 |
2002-02-21 |
Eli Lilly And Company |
Novel secreted proteins and their uses
|
|
US6369232B1
(en)
|
2000-08-15 |
2002-04-09 |
Hoffmann-La Roche Inc. |
Tetrazolyl-phenyl acetamide glucokinase activators
|
|
WO2002014500A2
(en)
|
2000-08-16 |
2002-02-21 |
Chiron Corporation |
Human genes and gene expression products
|
|
US7442765B2
(en)
|
2000-08-24 |
2008-10-28 |
Genentech, Inc. |
Secreted transmembrane polypeptides and nucleic acids encoding the same
|
|
AU2001284651A1
(en)
|
2000-08-24 |
2002-03-04 |
Eli Lilly And Company |
Secreted proteins and methods of using same
|
|
AU2001288390A1
(en)
|
2000-08-25 |
2002-03-04 |
Cor Therapeutics, Inc. |
Proteins and nucleic acids encoding same
|
|
US6346416B1
(en)
|
2000-08-29 |
2002-02-12 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of HPK/GCK-like kinase expression
|
|
US6849728B1
(en)
|
2000-08-31 |
2005-02-01 |
Wake Forest University Health Sciences |
GLUT10: a glucose transporter in the type 2 diabetes linked region of chromosome 20Q12-13.1
|
|
WO2002023184A1
(en)
|
2000-09-13 |
2002-03-21 |
Eleanor Roosevelt Institute |
Method for treatment of insulin resistance in obesity and diabetes
|
|
US20030187201A1
(en)
|
2000-09-15 |
2003-10-02 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20050048483A1
(en)
|
2000-09-28 |
2005-03-03 |
Su Eric Wen |
Novel secreted proteins and their uses
|
|
AU2002211220A1
(en)
|
2000-10-19 |
2002-04-29 |
Eli Lilly And Company |
Secreted proteins and their uses
|
|
WO2002057450A2
(en)
|
2000-11-29 |
2002-07-25 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
AU2002227239A1
(en)
|
2000-12-06 |
2002-06-18 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
ES2256340T3
(es)
|
2000-12-06 |
2006-07-16 |
F. Hoffmann-La Roche Ag |
Activadores heteroaromaticos fusionados de la glucoquinasa.
|
|
US6433188B1
(en)
|
2000-12-06 |
2002-08-13 |
Wendy Lea Corbett |
Fused heteroaromatic glucokinase activators
|
|
WO2002064791A2
(en)
|
2000-12-08 |
2002-08-22 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US6482951B2
(en)
|
2000-12-13 |
2002-11-19 |
Hoffmann-La Roche Inc. |
Isoindolin-1-one glucokinase activators
|
|
WO2002048361A2
(en)
|
2000-12-15 |
2002-06-20 |
Eli Lilly And Company |
Novel secreted proteins and their uses
|
|
AU2002246808A1
(en)
|
2000-12-19 |
2002-08-06 |
Curagen Corporation |
Human nucleic acids and polypeptides and methods of use thereof
|
|
CA2433313A1
(en)
|
2000-12-19 |
2002-07-25 |
Curagen Corporation |
Polypetides and nucleic acids encoding same
|
|
ES2170720B1
(es)
|
2000-12-20 |
2003-12-16 |
Univ Barcelona Autonoma |
Utilizacion conjunta del gen de la insulina y del gen de la glucoquinasa en el desarrollo de aproximaciones terapeuticas para la diabetes mellitus.
|
|
WO2002050277A2
(en)
|
2000-12-21 |
2002-06-27 |
Curagen Corporation |
Protein and nucleic acids encoding same
|
|
US7241579B2
(en)
|
2000-12-22 |
2007-07-10 |
Smithkline Beecham Corporation |
Method of screening for GPR40 ligands
|
|
US7247705B2
(en)
|
2000-12-28 |
2007-07-24 |
Takeda Pharmaceutical Company Limited |
Proteins having glucose transporter activity
|
|
WO2002055704A2
(en)
|
2001-01-09 |
2002-07-18 |
Curagen Corp |
Proteins, polynucleotides encoding them and methods of using the same
|
|
CA2433742A1
(en)
|
2001-01-11 |
2002-07-18 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
JP4146095B2
(ja)
|
2001-01-15 |
2008-09-03 |
ユニチカ株式会社 |
耐熱性グルコキナーゼ遺伝子、それを含有する組換えベクター、その組換えベクターを含有する形質転換体及びその形質転換体を用いた耐熱性グルコキナーゼの製造方法
|
|
HUP0401300A3
(en)
|
2001-01-18 |
2005-06-28 |
Merck Patent Gmbh |
Bifunctional fusion proteins with glucocerebrosidase activity
|
|
WO2002081517A2
(en)
|
2001-01-19 |
2002-10-17 |
Curagen Corporation |
Novel polypeptides and nucleic acids encoded thereby
|
|
GB0101447D0
(en)
|
2001-01-19 |
2001-03-07 |
Univ Edinburgh |
Regulation of glucocorticoid concentration
|
|
WO2002068649A2
(en)
|
2001-01-31 |
2002-09-06 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US20040081981A1
(en)
|
2001-01-31 |
2004-04-29 |
Toru Egashira |
Method of detecting risk factor for onset of diabetes
|
|
US20040086875A1
(en)
|
2001-11-05 |
2004-05-06 |
Agee Michele L. |
Novel proteins and nucleic acids encoding same
|
|
US20040053245A1
(en)
|
2001-02-05 |
2004-03-18 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
US7060675B2
(en)
|
2001-02-15 |
2006-06-13 |
Nobex Corporation |
Methods of treating diabetes mellitus
|
|
US6783969B1
(en)
|
2001-03-05 |
2004-08-31 |
Nuvelo, Inc. |
Cathepsin V-like polypeptides
|
|
WO2002072757A2
(en)
|
2001-03-08 |
2002-09-19 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
WO2002072875A1
(en)
|
2001-03-14 |
2002-09-19 |
The Chinese University Of Hong Kong |
Method and compositions for evaluating risk of developing type 2 diabetes in people of chinese descent
|
|
JP4602577B2
(ja)
|
2001-03-15 |
2010-12-22 |
積水メディカル株式会社 |
前糖尿病状態のスクリーニング方法及びスクリーニング用試薬
|
|
US7033790B2
(en)
|
2001-04-03 |
2006-04-25 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US7186818B2
(en)
|
2001-04-26 |
2007-03-06 |
Immunex Corporation |
DNA encoding soluble variants of human OX2 receptors
|
|
AU2002259209A1
(en)
|
2001-05-11 |
2002-11-25 |
Adipogenix, Inc. |
Methods and reagents for identifying insulin response modulators and therapeutic uses therefor
|
|
EP1393066A4
(en)
|
2001-05-15 |
2006-01-25 |
Rappaport Family Inst For Res |
INSULIN-PRODUCING CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS
|
|
DE60230988D1
(de)
|
2001-05-29 |
2009-03-12 |
Pride Proteomics As |
Proteine in der diabetes-proteomanalyse
|
|
AU2002312211A1
(en)
|
2001-06-01 |
2002-12-16 |
Clingenix, Inc. |
Methods and reagents for diagnosis and treatment of insulin resistance and related conditions
|
|
US7157558B2
(en)
|
2001-06-01 |
2007-01-02 |
Genentech, Inc. |
Polypeptide encoded by a polynucleotide overexpresses in tumors
|
|
JP2005501530A
(ja)
|
2001-06-08 |
2005-01-20 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
体細胞株におけるヒトインスリンのグルコース−調節された産生のために有用な核酸構築物
|
|
SE0102299D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
SE0102300D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
ATE433996T1
(de)
|
2001-07-03 |
2009-07-15 |
Genentech Inc |
Humane dr4-antikörper und deren anwendungen
|
|
SE0102764D0
(sv)
|
2001-08-17 |
2001-08-17 |
Astrazeneca Ab |
Compounds
|
|
AU2002349299A1
(en)
|
2001-12-03 |
2003-06-17 |
Novo Nordisk A/S |
Use of a glucokinase activator in combination with a glucagon antagonist for treating type 2 diabetes
|
|
US20030138416A1
(en)
|
2001-12-03 |
2003-07-24 |
Jesper Lau |
Use of glucokinase activator in combination with a glucagon antagonist for treating type 2 diabetes
|
|
US6911545B2
(en)
|
2001-12-19 |
2005-06-28 |
Hoffman-La Roche Inc. |
Crystals of glucokinase and methods of growing them
|
|
DE10162730A1
(de)
|
2001-12-20 |
2003-07-03 |
Degussa |
Allele des glk-Gens aus coryneformen Bakterien
|
|
IL162620A0
(en)
|
2001-12-21 |
2005-11-20 |
Novo Nordisk As |
Amide derivatives as gk activators
|
|
EP1572149A2
(en)
|
2002-03-07 |
2005-09-14 |
The Forsyth Institute |
Immunogenicity of glucan binding protein
|
|
AU2003221140B9
(en)
|
2002-03-26 |
2009-07-30 |
Banyu Pharmaceutical Co., Ltd. |
Novel aminobenzamide derivative
|
|
US20030232370A1
(en)
|
2002-04-22 |
2003-12-18 |
Trifiro Mark A. |
Glucose sensor and uses thereof
|
|
AU2003232204B8
(en)
|
2002-04-26 |
2009-07-30 |
F. Hoffmann-La Roche Ag |
Substituted phenylacetamides and their use as glucokinase activators
|
|
EP1507534A4
(en)
*
|
2002-05-10 |
2006-11-08 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
|
CA2490023A1
(en)
|
2002-05-16 |
2003-11-27 |
Banyu Pharmaceutical Co., Ltd. |
Crystal of glucokinase protein, and method for drug design using the crystal
|
|
EP1576370A2
(en)
|
2002-06-04 |
2005-09-21 |
Metabolex, Inc. |
Methods of diagnosing and treating diabetes and insulin resistance
|
|
WO2003102161A2
(en)
|
2002-06-04 |
2003-12-11 |
Metabolex, Inc. |
Methods of diagnosing & treating diabetes and insulin resistance
|
|
WO2003101284A2
(en)
|
2002-06-04 |
2003-12-11 |
Metabolex, Inc. |
Methods of diagnosing and treating diabetes and insulin resistance
|
|
AU2003237483A1
(en)
|
2002-06-05 |
2003-12-22 |
Metabolex, Inc. |
Methods of diagnosing and treating diabetes and insulin resistance
|
|
JP2006503265A
(ja)
|
2002-06-05 |
2006-01-26 |
メタボレックス インコーポレーティッド |
糖尿病およびインスリン抵抗性の診断および治療の方法
|
|
US20060210974A1
(en)
|
2002-06-13 |
2006-09-21 |
Metabolex, Inc. |
Compositions and methods for preventing, treating and diagnosing diabetes
|
|
KR101116627B1
(ko)
|
2002-06-27 |
2012-10-09 |
노보 노르디스크 에이/에스 |
치료제로서 아릴 카르보닐 유도체
|
|
KR100442832B1
(ko)
|
2002-07-10 |
2004-08-02 |
삼성전자주식회사 |
다중 중합효소 연쇄반응에 의한 mody2 유전자의증폭을 위한 프라이머 세트
|
|
WO2004006838A2
(en)
|
2002-07-15 |
2004-01-22 |
Sugen, Inc. |
Novel kinases
|
|
US7087631B2
(en)
|
2002-07-18 |
2006-08-08 |
Inotek Pharmaceuticals Corporation |
Aryltetrazole compounds, and compositions thereof
|
|
US20040132679A1
(en)
|
2002-09-03 |
2004-07-08 |
Baylor College Of Medicine |
Induction of pancreatic islet formation
|
|
NZ539013A
(en)
|
2002-10-03 |
2007-05-31 |
Novartis Ag |
Substituted (thiazol-2-yl) -amide or sulfonamide as glycokinase activators useful in the treatment of type 2 diabetes
|
|
MXPA05003391A
(es)
|
2002-10-03 |
2005-06-22 |
Hoffmann La Roche |
Indol-3-carboxamidas como activadores de glucocinasa.
|
|
US7132539B2
(en)
|
2002-10-23 |
2006-11-07 |
The Procter & Gamble Company |
Melanocortin receptor ligands
|
|
US20040143110A1
(en)
|
2002-10-28 |
2004-07-22 |
Krolewski Andrzej S. |
Type 2 diabetes mellitus genes
|
|
US20040108226A1
(en)
|
2002-10-28 |
2004-06-10 |
Constantin Polychronakos |
Continuous glucose quantification device and method
|
|
GB0226931D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0226930D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
US7132425B2
(en)
|
2002-12-12 |
2006-11-07 |
Hoffmann-La Roche Inc. |
5-substituted-six-membered heteroaromatic glucokinase activators
|
|
DE10258885A1
(de)
|
2002-12-17 |
2004-07-15 |
Aventis Pharma Deutschland Gmbh |
Verfahren zur Generierung eines gentechnisch veränderten Organismus
|
|
EP1585739B1
(en)
|
2003-01-06 |
2011-04-20 |
Eli Lilly And Company |
Substituted arylcyclopropylacetamides as glucokinase activators
|
|
AU2003294376A1
(en)
|
2003-01-06 |
2004-08-10 |
Eli Lilly And Company |
Heteroaryl compounds
|
|
WO2004069194A2
(en)
|
2003-02-03 |
2004-08-19 |
The Brigham And Women's Hospital, Inc. |
Use of the oxidoreductase ncb50r for diagnosings and treating diabetes
|
|
PL378117A1
(pl)
*
|
2003-02-11 |
2006-03-06 |
Prosidion Limited |
Tricyklopodstawione związki amidowe
|
|
EP1594863A1
(en)
*
|
2003-02-11 |
2005-11-16 |
Prosidion Limited |
Tri(cyclo) substituted amide glucokinase activator compounds
|
|
MXPA05008619A
(es)
|
2003-02-13 |
2005-11-04 |
Banyu Pharma Co Ltd |
Derivados novedosos de 2-piridincarboxamida.
|
|
EP1600442B1
(en)
|
2003-02-26 |
2018-01-17 |
Msd K.K. |
Heteroarylcarbamoylbenzene derivative
|
|
US7166692B2
(en)
|
2003-03-04 |
2007-01-23 |
Canbrex Bio Science Walkersville, Inc. |
Intracellular delivery of small molecules, proteins, and nucleic acids
|
|
US20040180845A1
(en)
|
2003-03-13 |
2004-09-16 |
Newgard Christopher B. |
Methods and compositions for modulating glycogen synthesis and breakdown
|
|
US20040185548A1
(en)
|
2003-03-17 |
2004-09-23 |
Qun-Sheng Ji |
Hybrid receptors for efficient assay of modulators of receptor protein-tyrosine kinases
|
|
US20040198969A1
(en)
|
2003-04-01 |
2004-10-07 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
JPWO2004096806A1
(ja)
*
|
2003-04-30 |
2006-07-13 |
大日本住友製薬株式会社 |
縮合イミダゾール誘導体
|
|
US7179613B2
(en)
|
2003-05-05 |
2007-02-20 |
Vanderbilt University |
Methods of screening for a candidate modulator of glucokinase
|
|
WO2004099246A2
(en)
|
2003-05-09 |
2004-11-18 |
Novo Nordisk A/S |
Peptides for use in treating obesity
|
|
US20050008691A1
(en)
|
2003-05-14 |
2005-01-13 |
Arturo Siles Ortega |
Bicalutamide compositions
|
|
EP1625112B1
(en)
|
2003-05-14 |
2009-07-22 |
High Point Pharmaceuticals, LLC |
Novel compounds for treatment of obesity
|
|
WO2005009446A1
(en)
|
2003-07-17 |
2005-02-03 |
Cotherix, Inc. |
Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome
|
|
EP1680414A4
(en)
|
2003-08-01 |
2009-05-27 |
Janssen Pharmaceutica Nv |
SUBSTITUTED INDAZOLE-O-GLUCOSIDE
|
|
AU2004261663A1
(en)
|
2003-08-01 |
2005-02-10 |
Janssen Pharmaceutica N.V. |
Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides
|
|
WO2005014534A1
(en)
|
2003-08-08 |
2005-02-17 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds, compositions, and methods of use
|
|
WO2005030032A2
(en)
|
2003-09-22 |
2005-04-07 |
The Regents Of The University Of Colorado |
Use of islet glucose-6-phosphatase related protein as a diagnostic tool and therapeutic target for autoimmune diabetes
|
|
GB0327761D0
(en)
|
2003-11-29 |
2003-12-31 |
Astrazeneca Ab |
Compounds
|
|
GB0327760D0
(en)
|
2003-11-29 |
2003-12-31 |
Astrazeneca Ab |
Compounds
|
|
CN101035767A
(zh)
*
|
2004-08-12 |
2007-09-12 |
普洛希典有限公司 |
被取代的苯乙酰胺及其作为葡糖激酶激活剂的用途
|
|
EP2426128A1
(en)
*
|
2004-09-28 |
2012-03-07 |
Otsuka Pharmaceutical Co., Limited |
Carbostyril compound
|
|
JP5302012B2
(ja)
*
|
2006-03-08 |
2013-10-02 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
|
EP2004193A2
(en)
*
|
2006-03-13 |
2008-12-24 |
Merck & Co., Inc. |
Ophthalmic compositions for treating ocular hypertension
|
|
JP5415942B2
(ja)
*
|
2006-06-22 |
2014-02-12 |
プラナ バイオテクノロジー リミティッド |
処置の方法およびその処置に有用な薬剤
|
|
WO2010013161A1
(en)
*
|
2008-07-29 |
2010-02-04 |
Pfizer Inc. |
Fluorinated heteroaryls
|