SG11202104384PA - Substituted oxopyridine derivatives - Google Patents

Substituted oxopyridine derivatives

Info

Publication number
SG11202104384PA
SG11202104384PA SG11202104384PA SG11202104384PA SG11202104384PA SG 11202104384P A SG11202104384P A SG 11202104384PA SG 11202104384P A SG11202104384P A SG 11202104384PA SG 11202104384P A SG11202104384P A SG 11202104384PA SG 11202104384P A SG11202104384P A SG 11202104384PA
Authority
SG
Singapore
Prior art keywords
oxopyridine derivatives
substituted oxopyridine
substituted
derivatives
oxopyridine
Prior art date
Application number
SG11202104384PA
Inventor
Susanne Röhrig
Sebastian Essig
Pascal Ellerbrock
Sonja Anlauf
Thomas Neubauer
Alexander Hillisch
Katharina Meier
Stefan Heitmeier
Adrian Tersteegen
Martina Schäfer
Jan Stampfuss
Dieter Lang
Hongping Wang
Zengqiang Zou
Xianghai Meng
Kersten Gericke
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SG11202104384PA publication Critical patent/SG11202104384PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SG11202104384PA 2018-12-21 2019-12-18 Substituted oxopyridine derivatives SG11202104384PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2018122825 2018-12-21
PCT/EP2019/085983 WO2020127504A1 (en) 2018-12-21 2019-12-18 Substituted oxopyridine derivatives

Publications (1)

Publication Number Publication Date
SG11202104384PA true SG11202104384PA (en) 2021-05-28

Family

ID=69143542

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104384PA SG11202104384PA (en) 2018-12-21 2019-12-18 Substituted oxopyridine derivatives

Country Status (22)

Country Link
EP (1) EP3898633A1 (en)
JP (1) JP2022514303A (en)
KR (1) KR20210106504A (en)
CN (1) CN113474348A (en)
AR (1) AR117435A1 (en)
AU (1) AU2019407909B2 (en)
BR (1) BR112021009435A2 (en)
CA (1) CA3124220A1 (en)
CL (1) CL2021001613A1 (en)
CO (1) CO2021007908A2 (en)
CR (1) CR20210342A (en)
DO (1) DOP2021000128A (en)
EA (1) EA202191764A1 (en)
EC (1) ECSP21043895A (en)
IL (1) IL283990A (en)
JO (1) JOP20210161A1 (en)
MA (1) MA54521A (en)
MX (1) MX2021007508A (en)
PE (1) PE20211790A1 (en)
SG (1) SG11202104384PA (en)
TW (1) TW202039510A (en)
WO (1) WO2020127504A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111770917B (en) * 2018-03-15 2023-09-26 拜耳股份公司 Process for the preparation of two compounds
CN114105881B (en) 2020-08-31 2024-01-26 沈阳海诺威医药科技有限公司 Platelet aggregation inhibitor, and preparation method and application thereof
MX2023010629A (en) 2021-03-09 2023-09-19 Bayer Ag Pharmaceutical dosage forms com.
BR112023016298A2 (en) 2021-03-09 2023-10-03 Bayer Ag CRYSTALLINE FORMS OF (4S)-24-CHLORO-4-ETHYL-73-FLUORO-35-METHOXY-32,5-DIOXO-14-(TRIFLUORO-METHYL)-32H-6-AZA-3(4,1)- PYRIDINE-1(1)-[1,2,3]TRIAZOLA-2(1,2),7(1)-DIBENZENE-HEPTAPHAN-74-CARBOXAMIDE
WO2022189280A1 (en) 2021-03-09 2022-09-15 Bayer Aktiengesellschaft Solvates of (4s)-24-chloro-4-ethyl-73-fluoro-35-methoxy-32,5-dioxo-14-(trifluoro-methyl)-32 h-6- aza-3(4,1)-pyridina-1(1)-[1,2,3]triazola-2(1,2),7(1)-dibenzenaheptaphane-74-carboxamide
CN114560754A (en) * 2022-02-25 2022-05-31 滁州学院 Preparation method of alkyl alcohol
CN116874469B (en) * 2023-09-06 2023-11-10 成都施贝康生物医药科技有限公司 Oxo-pyridine compound, intermediate, preparation method and application thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
DE102006032824A1 (en) * 2006-07-14 2008-01-17 Bayer Healthcare Ag Substituted indazoles
EP2091947A2 (en) 2006-12-20 2009-08-26 Takeda San Diego, Inc. Glucokinase activators
WO2014160592A2 (en) 2013-03-27 2014-10-02 Merck Sharp & Dohme Corp. FACTOR XIa INHIBITORS
TWI633089B (en) * 2013-03-28 2018-08-21 拜耳製藥股份有限公司 Substituted oxopyridine derivatives
EP3024822B1 (en) 2013-07-23 2017-05-03 Bayer Pharma Aktiengesellschaft Substituted oxopyridine derivatives and their use as factor xia and plasma kallikrein inhibitors
JP6368367B2 (en) 2013-10-30 2018-08-01 バイエル ファーマ アクチエンゲゼルシャフト Substituted oxopyridine derivatives
ES2722423T3 (en) * 2014-09-24 2019-08-12 Bayer Pharma AG Substituted oxopyridine derivatives
ES2712886T3 (en) * 2014-09-24 2019-05-16 Bayer Pharma AG Derivatives of pyridobenzazepine and pyridobenzazocine that inhibit factor XIa
ES2713624T3 (en) 2014-09-24 2019-05-23 Bayer Pharma AG Substituted oxopyridine derivatives
EP3197872B1 (en) 2014-09-24 2019-01-30 Bayer Pharma Aktiengesellschaft (2h)-2-oxopyridines as faktor xia-inhibitors for treating thrombotic diseases
ES2694189T3 (en) 2014-09-24 2018-12-18 Bayer Pharma Aktiengesellschaft Substituted oxopyridine derivatives
EP3197880B1 (en) 2014-09-24 2018-10-24 Bayer Pharma Aktiengesellschaft Substituted oxopyridine derivatives with anti-inflammatory and anti-thrombotic effect
CN107428689A (en) * 2015-03-19 2017-12-01 拜耳制药股份公司 As the oxo pyridine derivative for treating thrombotic factor XI, plasma thromboplastin antecedent A inhibitor
JO3703B1 (en) 2015-07-09 2021-01-31 Bayer Pharma AG Substituted oxopyridine derivatives
WO2017037051A1 (en) 2015-09-04 2017-03-09 Bayer Pharma Aktiengesellschaft Substituted oxopyridine derivatives

Also Published As

Publication number Publication date
AU2019407909B2 (en) 2023-05-25
CO2021007908A2 (en) 2021-07-19
IL283990A (en) 2021-07-29
DOP2021000128A (en) 2021-09-30
TW202039510A (en) 2020-11-01
KR20210106504A (en) 2021-08-30
EA202191764A1 (en) 2021-10-22
ECSP21043895A (en) 2021-07-30
CR20210342A (en) 2021-08-09
PE20211790A1 (en) 2021-09-09
JOP20210161A1 (en) 2023-01-30
CA3124220A1 (en) 2020-06-25
MA54521A (en) 2022-03-30
AU2019407909A1 (en) 2021-05-27
BR112021009435A2 (en) 2021-08-17
CL2021001613A1 (en) 2021-12-03
JP2022514303A (en) 2022-02-10
AR117435A1 (en) 2021-08-04
WO2020127504A1 (en) 2020-06-25
EP3898633A1 (en) 2021-10-27
CN113474348A (en) 2021-10-01
MX2021007508A (en) 2021-08-05

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