JP2010162030A5 - - Google Patents
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- Publication number
- JP2010162030A5 JP2010162030A5 JP2010036225A JP2010036225A JP2010162030A5 JP 2010162030 A5 JP2010162030 A5 JP 2010162030A5 JP 2010036225 A JP2010036225 A JP 2010036225A JP 2010036225 A JP2010036225 A JP 2010036225A JP 2010162030 A5 JP2010162030 A5 JP 2010162030A5
- Authority
- JP
- Japan
- Prior art keywords
- library
- phage
- kunitz domain
- protein
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 28
- 239000002245 particle Substances 0.000 claims 17
- 102000004169 proteins and genes Human genes 0.000 claims 14
- 101710132601 Capsid protein Proteins 0.000 claims 11
- 101710094648 Coat protein Proteins 0.000 claims 11
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 claims 11
- 101710125418 Major capsid protein Proteins 0.000 claims 11
- 101710141454 Nucleoprotein Proteins 0.000 claims 11
- 101710083689 Probable capsid protein Proteins 0.000 claims 11
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 230000003993 interaction Effects 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 230000002458 infectious effect Effects 0.000 claims 3
- 241000724791 Filamentous phage Species 0.000 claims 1
- 108091005804 Peptidases Proteins 0.000 claims 1
- 239000004365 Protease Substances 0.000 claims 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43849103P | 2003-01-07 | 2003-01-07 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500832A Division JP2007524348A (ja) | 2003-01-07 | 2004-01-07 | クニッツドメインライブラリー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010162030A JP2010162030A (ja) | 2010-07-29 |
| JP2010162030A5 true JP2010162030A5 (OSRAM) | 2011-06-30 |
Family
ID=32713336
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500832A Pending JP2007524348A (ja) | 2003-01-07 | 2004-01-07 | クニッツドメインライブラリー |
| JP2010036225A Pending JP2010162030A (ja) | 2003-01-07 | 2010-02-22 | クニッツドメインライブラリー |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500832A Pending JP2007524348A (ja) | 2003-01-07 | 2004-01-07 | クニッツドメインライブラリー |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20040209243A1 (OSRAM) |
| EP (2) | EP1587907B1 (OSRAM) |
| JP (2) | JP2007524348A (OSRAM) |
| AT (1) | ATE500345T1 (OSRAM) |
| AU (1) | AU2004204095B2 (OSRAM) |
| CA (1) | CA2512590A1 (OSRAM) |
| DE (1) | DE602004031589D1 (OSRAM) |
| DK (1) | DK1587907T3 (OSRAM) |
| ES (1) | ES2362424T3 (OSRAM) |
| PT (1) | PT1587907E (OSRAM) |
| WO (1) | WO2004063337A2 (OSRAM) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69533544T2 (de) * | 1994-01-11 | 2006-02-23 | Dyax Corp., Cambridge | Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten |
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| PT1941867E (pt) | 2002-06-07 | 2012-02-16 | Dyax Corp | Polipeptídeo contendo um domínio kunitz modificado |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| US20060111296A1 (en) * | 2004-11-22 | 2006-05-25 | Dyax Corp. | Plasmin-inhibitory therapies |
| WO2007009069A2 (en) * | 2005-07-13 | 2007-01-18 | Amgen Mountain View Inc. | Heat lysis production of proteins |
| US20090075887A1 (en) * | 2007-08-21 | 2009-03-19 | Genzyme Corporation | Treatment with Kallikrein Inhibitors |
| SI2379096T1 (sl) | 2008-12-19 | 2020-03-31 | Baxalta GmbH | Zaviralci TFPI in postopki uporabe |
| JP2013516389A (ja) | 2009-01-06 | 2013-05-13 | ダイアックス コーポレーション | カリクレイン阻害剤による粘膜炎治療 |
| HRP20181419T1 (hr) | 2010-01-06 | 2018-11-16 | Dyax Corp. | Plazma kalikrein vezni proteini |
| CA2793465C (en) | 2010-03-19 | 2022-06-14 | Baxter International Inc. | Tfpi inhibitors and methods of use |
| IL269565B2 (en) | 2011-01-06 | 2024-06-01 | Dyax Corp | Plasma kallikrein binding proteins |
| NZ724133A (en) | 2012-03-21 | 2020-07-31 | Baxalta Inc | Tfpi inhibitors and methods of use |
| WO2014024914A1 (ja) | 2012-08-08 | 2014-02-13 | 第一三共株式会社 | ペプチド・ライブラリー及びその利用 |
| KR102555955B1 (ko) | 2014-03-27 | 2023-07-18 | 다케다 파머수티컬 컴패니 리미티드 | 당뇨병성 황반 부종의 치료를 위한 조성물 및 방법 |
| KR102357893B1 (ko) | 2014-08-05 | 2022-02-04 | 맵퀘스트 에스아 | Pd-1 에 결합하는 면역학적 시약 |
| US9982052B2 (en) | 2014-08-05 | 2018-05-29 | MabQuest, SA | Immunological reagents |
| EP3970748B1 (en) | 2014-12-24 | 2024-07-24 | NexImmune, Inc. | Nanoparticle compositions and methods for immunotherapy |
| EP3371311B1 (en) | 2015-11-06 | 2021-07-21 | Orionis Biosciences BV | Bi-functional chimeric proteins and uses thereof |
| KR20180081608A (ko) | 2015-11-19 | 2018-07-16 | 아스클리픽스 테라퓨틱스, 엘엘씨. | 항-혈관형성, 항-림프관신생, 및 항-부종성 특성을 가진 펩티드 및 나노입자 제제 |
| WO2017100679A1 (en) | 2015-12-11 | 2017-06-15 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| US11214617B2 (en) | 2016-01-22 | 2022-01-04 | MabQuest SA | Immunological reagents |
| DK3964529T3 (da) | 2016-01-22 | 2025-06-30 | MabQuest SA | Ikke-blokerende pd1-specifikke antistoffer |
| EP3411065B1 (en) | 2016-02-05 | 2021-03-31 | Orionis Biosciences BV | Clec9a binding agents |
| US11248057B2 (en) | 2016-03-07 | 2022-02-15 | Vib Vzw | CD20 binding single domain antibodies |
| CN109689087B (zh) | 2016-05-13 | 2023-04-04 | 奥里尼斯生物科学私人有限公司 | 靶向性突变干扰素-β及其用途 |
| EP3455245A2 (en) | 2016-05-13 | 2019-03-20 | Orionis Biosciences NV | Therapeutic targeting of non-cellular structures |
| KR20190066040A (ko) | 2016-10-04 | 2019-06-12 | 아스클리픽스 테라퓨틱스, 인크. | Tie2 신호전달을 활성화시키기 위한 화합물 및 방법 |
| ES2917000T3 (es) | 2016-10-24 | 2022-07-06 | Orionis Biosciences BV | Interferón-gamma mutante diana y usos del mismo |
| EP3577133A1 (en) | 2017-02-06 | 2019-12-11 | Orionis Biosciences NV | Targeted chimeric proteins and uses thereof |
| US10906985B2 (en) | 2017-02-06 | 2021-02-02 | Orionis Biosciences, Inc. | Targeted engineered interferon and uses thereof |
| EP3580230A1 (en) | 2017-02-07 | 2019-12-18 | VIB vzw | Immune-cell targeted bispecific chimeric proteins and uses thereof |
| WO2019028427A1 (en) | 2017-08-03 | 2019-02-07 | Asclepix Therapeutics, Llc. | METHODS OF IDENTIFYING AND PREPARING PHARMACEUTICAL AGENTS TO ACTIVATE TIE2 RECEPTOR |
| WO2019075056A1 (en) | 2017-10-10 | 2019-04-18 | The Johns Hopkins University | BIODEGRADABLE BIOMIMETIC PARTICLES |
| EP3706801A4 (en) | 2017-11-08 | 2022-04-06 | L.E.A.F Holdings Group LLC | PLATINUM COMPLEXES AND USES THEREOF |
| IL314701A (en) | 2017-11-14 | 2024-10-01 | Arcellx Inc | Multifunctional immune cell therapies |
| WO2019148089A1 (en) | 2018-01-26 | 2019-08-01 | Orionis Biosciences Inc. | Xcr1 binding agents and uses thereof |
| WO2019152979A1 (en) | 2018-02-05 | 2019-08-08 | Orionis Biosciences, Inc. | Fibroblast binding agents and use thereof |
| US12410225B2 (en) | 2018-11-08 | 2025-09-09 | Orionis Biosciences, Inc | Modulation of dendritic cell lineages |
| CN113661175A (zh) | 2019-02-15 | 2021-11-16 | 整体分子公司 | 包含共同轻链的抗体及其用途 |
| CA3129834A1 (en) | 2019-02-15 | 2020-08-20 | Integral Molecular, Inc. | Claudin 6 antibodies and uses thereof |
| CA3149914A1 (en) | 2019-08-06 | 2021-02-11 | L.E.A.F. Holdings Group Llc | Processes of preparing polyglutamated antifolates and uses of their compositions |
| GB202004514D0 (en) | 2020-03-27 | 2020-05-13 | Inst De Medicina Molecular Joaeo Lobo Antunes | Treatment of Immunosuppressive Cancer |
| PE20231202A1 (es) | 2020-10-14 | 2023-08-17 | Viridian Therapeutics Inc | Composiciones y metodos para el tratamiento de la enfermedad ocular tiroidea |
| GB202019817D0 (en) * | 2020-12-15 | 2021-01-27 | Univ Oxford Innovation Ltd | Ligand-binding polypeptides and uses thereof |
| EP4313083A4 (en) | 2021-03-26 | 2025-06-18 | Arcellx, Inc. | MULTIFUNCTIONAL IMMUNE CELL THERAPIES |
| TW202320850A (zh) | 2021-08-10 | 2023-06-01 | 美商維里迪恩醫療股份有限公司 | 用於治療甲狀腺眼病之組合物、劑量及方法 |
| EP4551600A1 (en) | 2022-07-04 | 2025-05-14 | Vib Vzw | Blood-cerebrospinal fluid barrier crossing antibodies |
| CN120322459A (zh) | 2022-10-06 | 2025-07-15 | 比卡拉治疗股份有限公司 | 多特异性蛋白及相关方法 |
| EP4626933A1 (en) | 2022-11-30 | 2025-10-08 | Integral Molecular, Inc. | Antibodies directed to claudin 6, including bispecific formats thereof |
| AU2024243709A1 (en) | 2023-04-03 | 2025-11-06 | Katholieke Universiteit Leuven | Blood-brain barrier crossing antibodies |
| TW202509078A (zh) | 2023-07-07 | 2025-03-01 | 美商維里迪恩醫療股份有限公司 | 治療慢性甲狀腺眼病之方法 |
| WO2025024334A1 (en) | 2023-07-21 | 2025-01-30 | Marrow Therapeutics, Inc. | Hematopoietic cell targeting conjugates and related methods |
| WO2025093683A1 (en) | 2023-11-03 | 2025-05-08 | Neuvasq Biotechnologies Sa | Wnt7 signaling agonists |
| TW202535948A (zh) | 2023-12-17 | 2025-09-16 | 美商維里迪恩醫療股份有限公司 | 用於治療甲狀腺眼病之組合物、劑量及方法 |
| WO2025151496A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| WO2025151492A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| WO2025151502A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Modified antibodies |
| WO2025160334A1 (en) | 2024-01-26 | 2025-07-31 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor inhibitory proteins and related methods |
| US20250353881A1 (en) | 2024-05-16 | 2025-11-20 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor inhibitory proteins and related methods |
| WO2025245111A1 (en) | 2024-05-22 | 2025-11-27 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor targeting proteins and related methods |
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-
2004
- 2004-01-07 WO PCT/US2004/000333 patent/WO2004063337A2/en not_active Ceased
- 2004-01-07 DK DK04700617.6T patent/DK1587907T3/da active
- 2004-01-07 JP JP2006500832A patent/JP2007524348A/ja active Pending
- 2004-01-07 PT PT04700617T patent/PT1587907E/pt unknown
- 2004-01-07 DE DE602004031589T patent/DE602004031589D1/de not_active Expired - Lifetime
- 2004-01-07 EP EP04700617A patent/EP1587907B1/en not_active Expired - Lifetime
- 2004-01-07 EP EP10012620A patent/EP2290107A1/en not_active Withdrawn
- 2004-01-07 ES ES04700617T patent/ES2362424T3/es not_active Expired - Lifetime
- 2004-01-07 AU AU2004204095A patent/AU2004204095B2/en not_active Ceased
- 2004-01-07 US US10/753,544 patent/US20040209243A1/en not_active Abandoned
- 2004-01-07 CA CA002512590A patent/CA2512590A1/en not_active Abandoned
- 2004-01-07 AT AT04700617T patent/ATE500345T1/de active
-
2007
- 2007-07-09 US US11/774,964 patent/US20080020394A1/en not_active Abandoned
-
2010
- 2010-02-22 JP JP2010036225A patent/JP2010162030A/ja active Pending
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