JP2018138049A5 - - Google Patents

Download PDF

Info

Publication number
JP2018138049A5
JP2018138049A5 JP2018088729A JP2018088729A JP2018138049A5 JP 2018138049 A5 JP2018138049 A5 JP 2018138049A5 JP 2018088729 A JP2018088729 A JP 2018088729A JP 2018088729 A JP2018088729 A JP 2018088729A JP 2018138049 A5 JP2018138049 A5 JP 2018138049A5
Authority
JP
Japan
Prior art keywords
peptide
amino acid
acid sequence
seq
nos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018088729A
Other languages
English (en)
Japanese (ja)
Other versions
JP6603964B2 (ja
JP2018138049A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2018138049A publication Critical patent/JP2018138049A/ja
Publication of JP2018138049A5 publication Critical patent/JP2018138049A5/ja
Application granted granted Critical
Publication of JP6603964B2 publication Critical patent/JP6603964B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018088729A 2011-04-26 2018-05-02 組織再生を誘導するためのペプチドとその利用 Active JP6603964B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2011098270 2011-04-26
JP2011098270 2011-04-26
JP2011219454 2011-10-03
JP2011219454 2011-10-03

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2016214996A Division JP6336549B2 (ja) 2011-04-26 2016-11-02 組織再生を誘導するためのペプチドとその利用

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019175276A Division JP2020058344A (ja) 2011-04-26 2019-09-26 組織再生を誘導するためのペプチドとその利用

Publications (3)

Publication Number Publication Date
JP2018138049A JP2018138049A (ja) 2018-09-06
JP2018138049A5 true JP2018138049A5 (OSRAM) 2018-12-13
JP6603964B2 JP6603964B2 (ja) 2019-11-13

Family

ID=47071995

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2013511983A Active JP6069191B2 (ja) 2011-04-26 2012-04-03 組織再生を誘導するためのペプチドとその利用
JP2016214996A Active JP6336549B2 (ja) 2011-04-26 2016-11-02 組織再生を誘導するためのペプチドとその利用
JP2018088729A Active JP6603964B2 (ja) 2011-04-26 2018-05-02 組織再生を誘導するためのペプチドとその利用
JP2019175276A Pending JP2020058344A (ja) 2011-04-26 2019-09-26 組織再生を誘導するためのペプチドとその利用
JP2021129955A Pending JP2021191271A (ja) 2011-04-26 2021-08-06 組織再生を誘導するためのペプチドとその利用
JP2023084251A Pending JP2023106525A (ja) 2011-04-26 2023-05-23 組織再生を誘導するためのペプチドとその利用

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2013511983A Active JP6069191B2 (ja) 2011-04-26 2012-04-03 組織再生を誘導するためのペプチドとその利用
JP2016214996A Active JP6336549B2 (ja) 2011-04-26 2016-11-02 組織再生を誘導するためのペプチドとその利用

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019175276A Pending JP2020058344A (ja) 2011-04-26 2019-09-26 組織再生を誘導するためのペプチドとその利用
JP2021129955A Pending JP2021191271A (ja) 2011-04-26 2021-08-06 組織再生を誘導するためのペプチドとその利用
JP2023084251A Pending JP2023106525A (ja) 2011-04-26 2023-05-23 組織再生を誘導するためのペプチドとその利用

Country Status (12)

Country Link
US (4) US10364276B2 (OSRAM)
EP (2) EP2703487B1 (OSRAM)
JP (6) JP6069191B2 (OSRAM)
KR (2) KR101992807B1 (OSRAM)
CN (3) CN114106139B (OSRAM)
AU (4) AU2012248676B2 (OSRAM)
CA (1) CA2834255C (OSRAM)
DK (2) DK3358011T3 (OSRAM)
ES (2) ES2684718T3 (OSRAM)
PL (2) PL3358011T3 (OSRAM)
PT (2) PT3358011T (OSRAM)
WO (1) WO2012147470A1 (OSRAM)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110017371A (ko) 2008-04-30 2011-02-21 가부시키가이샤 제노믹스 생체내 기능적 세포의 고효율 채취법
KR20120135190A (ko) 2009-10-28 2012-12-12 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제
RU2647467C2 (ru) * 2012-10-25 2018-03-15 Дженомикс Ко., Лтд. Новый способ лечения инфаркта миокарда с применением фрагмента hmgb1
WO2014065348A1 (ja) 2012-10-25 2014-05-01 株式会社ジェノミックス Hmgb1断片を利用した脊髄の損傷に対する新規治療法
EP3888640B1 (en) 2013-06-05 2025-09-17 Reverse Bioengineering, Inc. Compositions and methods for induced tissue regeneration in mammalian species
EP4154914B1 (en) 2015-05-07 2024-08-28 University of South Florida Modified ube3a gene for a gene therapy approach for angelman syndrome
CA3202332A1 (en) 2015-12-07 2017-06-15 Agex Therapeutics, Inc. Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells
CN106995796A (zh) * 2016-01-26 2017-08-01 李建业 基于细胞因子的细胞处理方法、试剂盒及冻干粉
CN109310741A (zh) * 2016-04-29 2019-02-05 阿拉伊姆药品公司 用于预防和治疗与组织损伤相关的疾病和障碍的组织保护肽
CN110022867A (zh) 2016-09-21 2019-07-16 斯蒂芬·H·索恩 高迁移率族蛋白box i突变体
ES3018357T3 (es) 2017-01-27 2025-05-16 Stemrim Inc Agente terapéutico para miocardiopatía, el infarto de miocardio previo e insuficiencia cardíaca crónica
JPWO2018186480A1 (ja) * 2017-04-07 2020-02-20 株式会社ステムリム 線維性疾患の治療薬
US20210163552A1 (en) 2017-04-25 2021-06-03 Shionogi & Co., Ltd. Peptide for inducing regeneration of tissue, and use thereof
JPWO2019107566A1 (ja) * 2017-12-01 2020-12-03 株式会社ステムリム 外胚葉性間葉系幹細胞およびその製造方法
US11298403B2 (en) 2017-12-01 2022-04-12 StemRIM Inc. Therapeutic agent for inflammatory bowel disease
WO2019156137A1 (ja) 2018-02-08 2019-08-15 株式会社ステムリム 乾癬の治療薬
US12304933B2 (en) 2018-10-05 2025-05-20 StemRIM Inc. Disease treatment drug based on mesenchymal-stem-cell mobilization
EP3862017A4 (en) * 2018-10-05 2022-08-03 Stemrim Inc. PEPTIDE WITH MESENCHYMAL STEM CELL MOBILIZATION ACTIVITY
CN113423466B (zh) 2018-10-25 2025-04-25 国立大学法人大阪大学 软骨病症的治疗剂
CN113795501A (zh) * 2019-03-26 2021-12-14 国立大学法人新潟大学 肽及其应用
CN109957015A (zh) * 2019-04-01 2019-07-02 中国人民解放军海军军医大学国家肝癌科学中心 一种hmgb1封闭性抗体的制备方法及其应用
EP4058033A1 (en) * 2019-11-12 2022-09-21 Oxford University Innovation Limited Polypeptides related to hmgb1 useful for promoting tissue regeneration, compositions comprising same, and uses thereof
EP4144359A4 (en) * 2020-04-03 2024-05-01 Stemrim Inc. Peptide having mesenchymal stem cell mobilizing activity
JP7750489B2 (ja) * 2020-04-20 2025-10-07 塩野義製薬株式会社 Hmgb1部分ペプチドを含有する製剤
JP7455433B2 (ja) * 2020-04-22 2024-03-26 チュラーロンコーン ユニバーシティー Dnaを回復する及びdna損傷を防止する組成物及び方法
EP4257703A4 (en) * 2020-12-07 2025-06-04 Samsung Life Public Welfare Foundation Method for selecting mesenchymal stem cells with improved self-sustainability and thereby selected mesenchymal stem cells
JP2024518125A (ja) * 2021-05-19 2024-04-24 オックスフォード ユニバーシティ イノベーション リミテッド 組織再生の促進に有用なhmgb1関連ポリペプチド、それを含む組成物及びその使用
CA3233234A1 (en) 2021-09-30 2023-04-06 Katsuto Tamai Drug for treating fatty liver and nonalcoholic steatohepatitis
CN116983471B (zh) * 2023-06-07 2024-03-08 华中科技大学同济医学院附属协和医院 一种基于α-螺旋双亲性多肽的超分子共组装凝胶的制备方法及应用

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5238680B2 (OSRAM) 1972-12-27 1977-09-30
US4732155A (en) 1985-08-27 1988-03-22 The Children's Medical Center Corporation Implantable chemoattractant system
US5658894A (en) 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
US5661127A (en) 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
JP3018313B2 (ja) 1996-02-23 2000-03-13 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
US20040031072A1 (en) * 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
AU778386B2 (en) 1999-07-28 2004-12-02 Board Of Trustees Of The Leland Stanford Junior University Nicotine receptor agonists in stem cell and progenitor cell recruitment
EP1263931A4 (en) 1999-11-05 2009-07-15 Gerigene Medical Corp INCREASE AND REPAIR OF IMPERFECTIONS OF SOFT TISSUES RELATED TO AGE
EP1114862A3 (de) 1999-11-17 2003-08-06 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen
KR20030032922A (ko) 2000-02-24 2003-04-26 싸이트 테라피스 인코포레이티드 세포의 동시 자극 및 농축
JP3421741B2 (ja) 2000-05-18 2003-06-30 筑波大学長 人工骨髄、血球細胞の増殖方法
US7754217B2 (en) 2001-03-16 2010-07-13 Bio3 Research Srl HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases
WO2002088181A2 (en) 2001-04-30 2002-11-07 Switch Biotech Ag Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances
DE10121254A1 (de) 2001-04-30 2002-11-07 Switch Biotech Ag MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
US7304034B2 (en) 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
CZ20033402A3 (cs) 2001-05-15 2004-10-13 Northáshore@Longáislandájewisháresearcháinstitute Použití fragmentů HMG jako protizánětlivých činidel
ITMI20011986A1 (it) 2001-09-25 2003-03-25 San Raffaele Centro Fond Metodo e composizione per l'attivazione di cellule presentanti l'antigene
JPWO2003043651A1 (ja) 2001-11-19 2005-03-10 協和醗酵工業株式会社 多分化能幹細胞を組織から末梢血へ動員する薬剤
EP2305276A3 (en) 2001-12-07 2011-09-21 Cytori Therapeutics, Inc. Processed lipoaspirate cells for use in therapy
FR2833609B1 (fr) 2001-12-19 2004-12-03 Natural Implant Dispositif de prelevement cellulaire ou tissulaire en phase active et utilisations
CN1671742A (zh) 2002-07-03 2005-09-21 塔博尔山圣拉弗尔基金中心 Hmgb1在治疗组织损伤和/或促进组织修复中的用途
DE60327075D1 (de) 2002-07-05 2009-05-20 Univ Laval Der entzündungsreaktionen
GB0226251D0 (en) 2002-11-11 2002-12-18 San Raffaele Centro Fond Acetylated protein
US20040156851A1 (en) 2002-11-20 2004-08-12 Critical Therapeutics, Inc. HMGB1 combination therapies
AU2003294488B2 (en) 2002-11-20 2007-05-24 Critical Therapeutics, Inc. Use of HMGB fragments as anti-inflammatory agents
WO2004061456A2 (de) 2003-01-03 2004-07-22 Alcedo Biotech Gmbh Verwendungen von hmgb, hmgn, hmga proteinen
WO2004075855A2 (en) 2003-02-26 2004-09-10 Biomed Solutions, Llc Process for in vivo treatment of specific biological targets in bodily fluid
CN1193092C (zh) 2003-03-28 2005-03-16 浙江大学 骨髓间充质干细胞分离和体外扩增培养方法
DE602004017148D1 (de) 2003-03-28 2008-11-27 Univ Laval S100 protein als aktivator neutrophiler zellen zur verminderung der neutropenie bei der krebsbehandlung
US20090069227A9 (en) 2003-04-29 2009-03-12 Capogrossi Maurizio C Use of HMGB1 to promote stem cell migration and/or proliferation
US20050014255A1 (en) 2003-05-29 2005-01-20 Board Of Regents, The University Of Texas System Stem cells for clinical and commercial uses
WO2005025604A2 (en) 2003-09-10 2005-03-24 The General Hospital Corporation Use of hmgb and hmgb fragments to decrease specific immune response
AU2004272607B2 (en) 2003-09-11 2008-11-06 Cornerstone Therapeutics Inc. Monoclonal antibodies against HMGB1
ITRM20040058A1 (it) 2004-02-03 2004-05-03 Marco E Bianchi Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali.
WO2006008779A1 (en) 2004-07-20 2006-01-26 Provincia Italiana Della Congregazione Dei Figli Dell'immacolata Concezione-Istituto Dermopatico Dell'immacolata Use of hmgb1 for wound healing
MX2007001155A (es) 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
AU2005279308B2 (en) * 2004-09-03 2012-05-03 Creabilis Therapeutics S.R.L. Protease resistant human and non-human HMGB1 Box-A mutants and their therapeutic/diagnostic use
CA2585043A1 (en) 2004-10-22 2007-01-04 Medimmune, Inc. High affinity antibodies against hmgb1 and methods of use thereof
KR100593397B1 (ko) 2004-10-27 2006-06-28 한국원자력연구소 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제
WO2006047820A1 (en) 2004-11-01 2006-05-11 Newsouth Innovations Pty Limited Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation
ITRM20050032A1 (it) 2005-01-21 2006-07-22 Marco E Bianchi Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.
WO2006080434A1 (ja) 2005-01-27 2006-08-03 Japan Health Sciences Foundation 間葉系幹細胞を含む細胞シート
DK1893253T3 (da) 2005-03-23 2010-08-16 Biosafe Sa Integreret system til opsamling, forarbejdning og transplantation af celledelmængder, omfattende voksenstamceller til regenerativ medicin
KR100775958B1 (ko) * 2005-03-30 2007-11-13 김정문 조직재생 기능을 가지는 비활성 폴리펩티드 및 그 제조방법
WO2006114805A2 (en) 2005-04-28 2006-11-02 Fondazione Centro San Raffaele Del Monte Tabor Use of hmgb2 and hmgb3 proteins for medical applications
US20100280493A1 (en) 2005-06-23 2010-11-04 Asha Nayak Methods and Systems for Treating Injured Cardiac Tissue
WO2007015546A1 (ja) 2005-08-04 2007-02-08 Genomix Co., Ltd 間葉系幹細胞誘導剤及び組織再生促進剤並びに間葉系幹細胞の調製方法
WO2007031100A1 (en) 2005-09-14 2007-03-22 Ostini, Marco Active immunotherapy of life-threatening systemic inflammation
WO2007061762A2 (en) * 2005-11-18 2007-05-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Healt And Human Services Non-viral gene delivery complex
US7829097B2 (en) 2006-02-06 2010-11-09 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of HMGB1 for protection against ischemia reperfusion injury
JP4982739B2 (ja) 2006-06-01 2012-07-25 国立大学法人 東京医科歯科大学 ポリグルタミン病の予防・治療剤
US8496931B2 (en) 2006-08-11 2013-07-30 Medarex, Inc. Monoclonal antibodies against stromal derived factor-1 (SDF-1)
WO2008031612A1 (en) 2006-09-15 2008-03-20 Creabilis Therapeutics S.P.A. Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1
ATE505205T1 (de) * 2006-09-15 2011-04-15 Creabilis Therapeutics Spa Polymerkonjugate von box-a von hmgb1 und box-a- varianten von hmgb1
EP2055308B1 (en) 2006-10-30 2017-05-10 Genomix Co., Ltd. Pharmaceutical for promoting functional regeneration of damaged tissue
CA2629652A1 (en) 2007-04-24 2008-10-24 Yaojiong Wu Compositions for preventing or treating skin defects and methods of use thereof
US8114668B2 (en) 2007-05-14 2012-02-14 Cardiac Pacemakers, Inc. Composition for cold storage of stem cells
AU2009240885A1 (en) 2008-04-30 2009-11-05 Genomix Co., Ltd. Pharmaceutical agent for promoting the functional regeneration of damaged tissue
KR20110017371A (ko) 2008-04-30 2011-02-21 가부시키가이샤 제노믹스 생체내 기능적 세포의 고효율 채취법
JP5660889B2 (ja) 2008-04-30 2015-01-28 株式会社ジェノミックス 末梢循環への骨髄由来多能性幹細胞動員薬
JP2013508013A (ja) 2009-10-16 2013-03-07 ザ ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー 細胞療法戦略を用いた慢性神経組織損傷の治療方法
KR20120135190A (ko) 2009-10-28 2012-12-12 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제
CN102443064A (zh) 2011-11-03 2012-05-09 刘誉 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用
RU2647467C2 (ru) 2012-10-25 2018-03-15 Дженомикс Ко., Лтд. Новый способ лечения инфаркта миокарда с применением фрагмента hmgb1
WO2014065348A1 (ja) 2012-10-25 2014-05-01 株式会社ジェノミックス Hmgb1断片を利用した脊髄の損傷に対する新規治療法

Similar Documents

Publication Publication Date Title
JP2018138049A5 (OSRAM)
JP2023082054A5 (OSRAM)
JP2020518268A5 (OSRAM)
JP2016034981A5 (OSRAM)
JP2009268467A5 (OSRAM)
JP2021501581A5 (OSRAM)
JP2017532966A5 (OSRAM)
JP2015521465A5 (OSRAM)
JP2012518420A5 (OSRAM)
JP2009525757A5 (OSRAM)
JP2012522501A5 (OSRAM)
JP2020520662A5 (OSRAM)
JP2018537087A5 (OSRAM)
JP2014500724A5 (OSRAM)
JP2018520997A5 (OSRAM)
JP2013530689A5 (OSRAM)
JP2018515096A5 (OSRAM)
JP2019500414A5 (OSRAM)
JP2017018125A5 (OSRAM)
JP2018531624A5 (OSRAM)
JP2014012022A5 (OSRAM)
JP2012095652A5 (OSRAM)
JP2005120106A5 (OSRAM)
JP2017514522A5 (OSRAM)
JP2021505201A5 (OSRAM)