JP2017528158A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017528158A5 JP2017528158A5 JP2017524110A JP2017524110A JP2017528158A5 JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5 JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- lentiviral vector
- vector
- antigen receptor
- chimeric antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020156063A JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028889P | 2014-07-25 | 2014-07-25 | |
| US62/028,889 | 2014-07-25 | ||
| US201562155811P | 2015-05-01 | 2015-05-01 | |
| US62/155,811 | 2015-05-01 | ||
| EP15306036.3 | 2015-06-29 | ||
| EP15306036 | 2015-06-29 | ||
| PCT/EP2015/067090 WO2016012623A1 (en) | 2014-07-25 | 2015-07-24 | Lentiviral vectors for regulated expression of a chimeric antigen receptor molecule |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Division JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017528158A JP2017528158A (ja) | 2017-09-28 |
| JP2017528158A5 true JP2017528158A5 (OSRAM) | 2018-08-30 |
| JP6940406B2 JP6940406B2 (ja) | 2021-09-29 |
Family
ID=53514131
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524110A Expired - Fee Related JP6940406B2 (ja) | 2014-07-25 | 2015-07-24 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10752668B2 (OSRAM) |
| EP (2) | EP3511413B1 (OSRAM) |
| JP (3) | JP6940406B2 (OSRAM) |
| CN (2) | CN107531800B (OSRAM) |
| CA (1) | CA2956385A1 (OSRAM) |
| WO (1) | WO2016012623A1 (OSRAM) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2746407C1 (ru) | 2012-02-23 | 2021-04-13 | Стейдж Селл Терапеутикс Гмбх | Хроматографическое выделение клеток и других сложных биологических материалов |
| CN108474002B (zh) * | 2015-10-22 | 2023-05-23 | 朱诺治疗学有限公司 | 用于转导的方法、反应剂盒、反应剂和设备 |
| WO2017180587A2 (en) * | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| CN108276493B (zh) * | 2016-12-30 | 2023-11-14 | 南京传奇生物科技有限公司 | 一种嵌合抗原受体及其应用 |
| SG11201909931PA (en) | 2017-04-27 | 2019-11-28 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| EP3618870A4 (en) | 2017-05-01 | 2021-04-21 | The Trustees of The University of Pennsylvania | MONOCLONAL ANTIBODIES AGAINST ALPHA-SYNUCLEIN FIBRILLES |
| US20200283485A1 (en) | 2017-10-20 | 2020-09-10 | Institut Curie | Hook fusion protein for regulating the cellular trafficking of a target protein |
| WO2019077165A1 (en) | 2017-10-20 | 2019-04-25 | Institut Curie | DAP10 / 12-BASED CHIMERIC ANTIGENIC RECEPTORS (CAR) ADAPTED FOR RUSH |
| CA3080109A1 (en) | 2017-11-03 | 2019-05-09 | Sorrento Therapeutics, Inc. | Cd38-directed chimeric antigen receptor constructs |
| BR112020014650A2 (pt) | 2018-01-17 | 2021-02-17 | Aratinga Bio Tnp | vetores virais encapsulados em polímero para terapia genética |
| EP3549597A1 (en) * | 2018-04-06 | 2019-10-09 | Heinrich-Heine-Universität Düsseldorf | Synthetic signalling constructs and its use |
| EP3781176A4 (en) * | 2018-04-09 | 2022-05-25 | The Trustees of the University of Pennsylvania | METHODS AND COMPOSITIONS USING A VIRAL VECTOR FOR THE EXPRESSION OF A TRANSGENE AND AN EFFECTOR |
| JP7721436B2 (ja) | 2018-04-12 | 2025-08-12 | ウモジャ バイオファーマ インコーポレイテッド | ウイルスベクター及びパッケージング細胞株 |
| EP3999540A1 (en) | 2019-07-16 | 2022-05-25 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Antibodies having specificity for cd38 and uses thereof |
| EP4028413A1 (en) | 2019-09-10 | 2022-07-20 | Obsidian Therapeutics, Inc. | Ca2-il15 fusion proteins for tunable regulation |
| GB201914611D0 (en) * | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| WO2022074464A2 (en) | 2020-03-05 | 2022-04-14 | Neotx Therapeutics Ltd. | Methods and compositions for treating cancer with immune cells |
| JP2023539761A (ja) * | 2020-09-01 | 2023-09-19 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | コカルエンベロープを使用したｔ細胞形質導入のためのレンチウイルスベクターの生成の改善 |
| EP4244240A1 (en) | 2020-11-13 | 2023-09-20 | Honing Biosciences | Means and methods for regulating intracellular trafficking of secretory or cell membrane-anchored proteins of interest |
| IT202100011576A1 (it) * | 2021-05-06 | 2022-11-06 | Univ Degli Studi Padova | Nuova sequenza promotore per terapia genica |
| EP4433081A1 (en) | 2021-11-15 | 2024-09-25 | Theravectys | Lentiviral vectors for expression of human papillomavirus (hpv) antigens and its implementation in the treatment of hpv induced cancers |
| CA3256704A1 (en) * | 2022-05-23 | 2023-11-30 | The Broad Institute, Inc. | METHODS AND COMPOSITIONS FOR CRISPR SCREENING OF IMMUNE CELLS |
| CN119894530A (zh) | 2022-07-27 | 2025-04-25 | 瑟拉维克提斯公司 | 用于表达人乳头瘤病毒(hpv)抗原的慢病毒载体及其在治疗hpv诱发的癌症中的应用 |
| US20250025165A1 (en) | 2023-07-21 | 2025-01-23 | Cilag Gmbh International | Systems and subsystems for articulating a surgical instrument |
| EP4624494A1 (en) | 2024-03-29 | 2025-10-01 | Institut Curie | Her2 single domain antibody and uses thereof |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| USRE32011E (en) | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4902614A (en) | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| JPS63501765A (ja) | 1985-11-01 | 1988-07-21 | インタ−ナショナル、ジェネティック、エンジニアリング インコ−ポレ−テッド | 抗体遺伝子のモジュ−ル組立体、それにより産生された抗体及び用途 |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| DE768377T1 (de) | 1988-09-02 | 1998-01-02 | Dyax Corp | Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| AU8507191A (en) | 1990-08-29 | 1992-03-30 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
| ES2287206T3 (es) | 1991-03-01 | 2007-12-16 | Dyax Corporation | Proceso para el desarrollo de mini-proteinas de union. |
| WO1992018619A1 (en) | 1991-04-10 | 1992-10-29 | The Scripps Research Institute | Heterodimeric receptor libraries using phagemids |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| DE4135543A1 (de) | 1991-10-28 | 1993-04-29 | Boehringer Mannheim Gmbh | Rekombinantes core-streptavidin |
| WO2000020587A2 (en) * | 1998-10-05 | 2000-04-13 | Ludwig Institute For Cancer Research | Cancer associated antigens and uses therefor |
| DK2169073T3 (da) | 1999-10-11 | 2014-02-10 | Pasteur Institut | Vektor til fremstilling af immunterapeutiske præparater |
| US6841359B2 (en) * | 2000-10-31 | 2005-01-11 | The General Hospital Corporation | Streptavidin-binding peptides and uses thereof |
| US7754208B2 (en) * | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| EP1390057A4 (en) * | 2001-04-03 | 2005-10-12 | Curagen Corp | ANTIBODIES BINDING TO ANTIGENOUS POLYPEPTIDES, NUCLEIC ACIDS COATING ANTIGENS, AND METHODS OF USE |
| WO2003076669A1 (es) * | 2002-03-08 | 2003-09-18 | Cueros Industrializados Del Bajio | Proceso para la incorporación de particulas termoestables a cuero o piel |
| US20050032173A1 (en) | 2003-08-05 | 2005-02-10 | Mauricio Rojas | Fusion proteins with a membrane translocating sequence and methods of using same to inhibit an immune response |
| US20130266551A1 (en) * | 2003-11-05 | 2013-10-10 | St. Jude Children's Research Hospital, Inc. | Chimeric receptors with 4-1bb stimulatory signaling domain |
| US7265205B2 (en) * | 2005-02-11 | 2007-09-04 | Uti Limited Partnership | Monomeric streptavidin muteins |
| US8293500B2 (en) * | 2006-03-22 | 2012-10-23 | Viral Logic Systems Technology Corp. | Methods for identifying polypeptide targets and uses thereof for treating immunological diseases |
| WO2008105968A1 (en) | 2006-11-03 | 2008-09-04 | Smithkline Beecham Corporation | Novel seh inhibitors and their use |
| EP2147683A1 (en) * | 2008-07-25 | 2010-01-27 | DKFZ Deutsches Krebsforschungszentrum | Construct and method for the internalization of cargo molecules into a cell |
| EP2440667A1 (en) * | 2009-06-11 | 2012-04-18 | Institut Curie | Methods and kits for regulating intracellular trafficking of a target protein |
| EP2651442B1 (en) * | 2010-12-14 | 2020-04-22 | University of Maryland, Baltimore | Universal anti-tag chimeric antigen receptor-expressing t cells and methods of treating cancer |
| EP2697256A1 (en) * | 2011-04-15 | 2014-02-19 | Compugen Ltd. | Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer |
| US20130071414A1 (en) * | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
| CA3205751A1 (en) * | 2012-02-22 | 2013-08-29 | The Trustees Of The University Of Pennsylvania | Use of icos-based cars to enhance antitumor activity and car persistence |
| IL293944A (en) * | 2012-08-20 | 2022-08-01 | Hutchinson Fred Cancer Res | Method and preparations for cellular immunotherapy |
| EP2906684B8 (en) | 2012-10-10 | 2020-09-02 | Sangamo Therapeutics, Inc. | T cell modifying compounds and uses thereof |
| MX386422B (es) * | 2013-12-20 | 2025-03-18 | Fred Hutchinson Cancer Center | Moléculas efectoras químericas etiquetadas y receptores de las mismas. |
| WO2017023803A1 (en) * | 2015-07-31 | 2017-02-09 | Regents Of The University Of Minnesota | Modified cells and methods of therapy |
-
2015
- 2015-07-24 WO PCT/EP2015/067090 patent/WO2016012623A1/en not_active Ceased
- 2015-07-24 EP EP19159129.6A patent/EP3511413B1/en active Active
- 2015-07-24 CN CN201580051938.9A patent/CN107531800B/zh active Active
- 2015-07-24 CN CN202110939899.3A patent/CN113846062B/zh active Active
- 2015-07-24 JP JP2017524110A patent/JP6940406B2/ja not_active Expired - Fee Related
- 2015-07-24 EP EP15742027.4A patent/EP3172228B1/en active Active
- 2015-07-24 CA CA2956385A patent/CA2956385A1/en active Pending
- 2015-07-24 US US15/327,517 patent/US10752668B2/en active Active
-
2020
- 2020-07-17 US US16/931,986 patent/US20210009653A1/en not_active Abandoned
- 2020-09-17 JP JP2020156063A patent/JP7341110B2/ja active Active
-
2023
- 2023-05-10 JP JP2023078059A patent/JP2023113656A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017528158A5 (OSRAM) | ||
| JP2016505635A5 (OSRAM) | ||
| JP2017537622A5 (OSRAM) | ||
| JP6816031B2 (ja) | 非標準的なｃｄ８＋ｔ細胞応答を生成するのに有用な方法および組成物 | |
| Cook et al. | HTLV-1: persistence and pathogenesis | |
| JP2019527055A5 (OSRAM) | ||
| JP2020074776A5 (OSRAM) | ||
| JP2016512557A5 (ja) | 二重特異性分子及びそれを用いた方法 | |
| JP2011530309A5 (OSRAM) | ||
| JP2014503206A5 (OSRAM) | ||
| JP2016501535A5 (OSRAM) | ||
| JP2015533841A5 (OSRAM) | ||
| JP2019509063A5 (OSRAM) | ||
| JP2015529678A5 (OSRAM) | ||
| MX375379B (es) | Receptores de celulas t anti - papilomavirus 16 e7 humano. | |
| JP2013521789A5 (OSRAM) | ||
| FI3872085T3 (fi) | Esimuotoiset virussekvenssit ja niiden käytöt | |
| RU2015155821A (ru) | Вакцины против малярии | |
| RU2015153250A (ru) | Cd19-специфический химерный антигенный рецептор и его применения | |
| JP2012095652A5 (OSRAM) | ||
| JP2013507907A5 (OSRAM) | ||
| JP2019519529A5 (OSRAM) | ||
| EA202090738A1 (ru) | Способ безопасного индуцирования иммунитета против rsv | |
| JP2015524422A5 (OSRAM) | ||
| RU2015135890A (ru) | Композиция вакцины |