JP2010053135A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010053135A5 JP2010053135A5 JP2009272679A JP2009272679A JP2010053135A5 JP 2010053135 A5 JP2010053135 A5 JP 2010053135A5 JP 2009272679 A JP2009272679 A JP 2009272679A JP 2009272679 A JP2009272679 A JP 2009272679A JP 2010053135 A5 JP2010053135 A5 JP 2010053135A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- symptom
- neutropenia
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000004235 neutropenia Diseases 0.000 claims description 10
- 210000000130 stem cell Anatomy 0.000 claims description 4
- 238000011282 treatment Methods 0.000 claims description 4
- 238000010322 bone marrow transplantation Methods 0.000 claims description 3
- 210000001185 bone marrow Anatomy 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 23
- 208000024891 symptom Diseases 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 9
- 206010065553 Bone marrow failure Diseases 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 238000001959 radiotherapy Methods 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 238000002512 chemotherapy Methods 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000008733 trauma Effects 0.000 claims 2
- 208000019838 Blood disease Diseases 0.000 claims 1
- 108010071942 Colony-Stimulating Factors Proteins 0.000 claims 1
- 102000007644 Colony-Stimulating Factors Human genes 0.000 claims 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 claims 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 claims 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 claims 1
- 101000746373 Homo sapiens Granulocyte-macrophage colony-stimulating factor Proteins 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 102000003812 Interleukin-15 Human genes 0.000 claims 1
- 108090000172 Interleukin-15 Proteins 0.000 claims 1
- 102000000588 Interleukin-2 Human genes 0.000 claims 1
- 108010002350 Interleukin-2 Proteins 0.000 claims 1
- 208000002720 Malnutrition Diseases 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- -1 fatty acid triglycerides Chemical class 0.000 claims 1
- 208000014951 hematologic disease Diseases 0.000 claims 1
- 208000018706 hematopoietic system disease Diseases 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 235000018343 nutrient deficiency Nutrition 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 230000001052 transient effect Effects 0.000 claims 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 claims 1
- 238000004904 shortening Methods 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28445801P | 2001-04-18 | 2001-04-18 | |
| US60/284,458 | 2001-04-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580924A Division JP5026655B2 (ja) | 2001-04-18 | 2002-04-18 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014165557A Division JP6420089B2 (ja) | 2001-04-18 | 2014-08-15 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010053135A JP2010053135A (ja) | 2010-03-11 |
| JP2010053135A5 true JP2010053135A5 (https=) | 2014-01-16 |
| JP5657879B2 JP5657879B2 (ja) | 2015-01-21 |
Family
ID=23090294
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580924A Expired - Lifetime JP5026655B2 (ja) | 2001-04-18 | 2002-04-18 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2009272679A Expired - Lifetime JP5657879B2 (ja) | 2001-04-18 | 2009-11-30 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2014165557A Expired - Lifetime JP6420089B2 (ja) | 2001-04-18 | 2014-08-15 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580924A Expired - Lifetime JP5026655B2 (ja) | 2001-04-18 | 2002-04-18 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014165557A Expired - Lifetime JP6420089B2 (ja) | 2001-04-18 | 2014-08-15 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7745488B2 (https=) |
| EP (2) | EP1385498B1 (https=) |
| JP (3) | JP5026655B2 (https=) |
| KR (1) | KR20030096323A (https=) |
| CN (1) | CN1633286A (https=) |
| AP (1) | AP1740A (https=) |
| AU (2) | AU2002308456B2 (https=) |
| BG (1) | BG66418B1 (https=) |
| BR (1) | BR0208984A (https=) |
| CA (2) | CA2444463C (https=) |
| CY (1) | CY1107081T1 (https=) |
| CZ (1) | CZ305273B6 (https=) |
| DE (1) | DE60223670T2 (https=) |
| DK (2) | DK1900364T3 (https=) |
| EA (1) | EA007322B1 (https=) |
| EE (1) | EE200300510A (https=) |
| ES (2) | ES2439738T3 (https=) |
| HU (1) | HUP0303817A3 (https=) |
| IL (3) | IL158322A0 (https=) |
| MX (1) | MXPA03009436A (https=) |
| NO (1) | NO335105B1 (https=) |
| NZ (2) | NZ541140A (https=) |
| OA (1) | OA12506A (https=) |
| PL (2) | PL223348B1 (https=) |
| PT (2) | PT1900364E (https=) |
| SI (1) | SI1385498T1 (https=) |
| SK (1) | SK12772003A3 (https=) |
| TN (1) | TNSN03089A1 (https=) |
| WO (1) | WO2002083120A2 (https=) |
| ZA (1) | ZA200307778B (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5026655B2 (ja) * | 2001-04-18 | 2012-09-12 | プロメティック、バイオサイエンシーズ、インコーポレーテッド | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| ATE419846T1 (de) * | 2003-02-07 | 2009-01-15 | Prometic Biosciences Inc | Fettsäuren mittlerer kettenlänge, glyceride und analoga als stimulatoren der erythropoiese |
| PT1648851E (pt) | 2003-07-25 | 2007-05-31 | Prometic Biosciences Inc | Praparação de sais metálicos de ácidos gordos de cadeia média |
| CA2563533C (en) * | 2004-04-15 | 2013-10-01 | Shmuel A. Ben-Sasson | Compositions capable of facilitating penetration across a biological barrier |
| US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| MX2007002727A (es) * | 2004-09-03 | 2008-03-04 | Prometic Biosciences Inc | Derivados de purinilo sustituidos con actividad inmunomoduladora y quimioprotectora, y su uso solos o con acidos grasos de longitud de cadena media o gliceridos. |
| US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| NZ554176A (en) * | 2004-10-01 | 2010-04-30 | Prometic Biosciences Inc | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| AU2006217544B8 (en) * | 2005-02-28 | 2012-04-05 | Alphabeta Ab | Compounds for reducing aggregation of amyloid beta-peptide |
| WO2007136424A2 (en) * | 2006-05-17 | 2007-11-29 | Cognate Therapeutics, Inc. | Isolation and purification of hematopoietic stem cells from post-liposuction lipoaspirates |
| WO2009017802A1 (en) | 2007-08-01 | 2009-02-05 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Nitro-fattyacid modulation of type ii diabetes |
| PT2299998T (pt) * | 2007-11-02 | 2018-04-02 | Prometic Pharma Smt Ltd | Acidos gordos e glicerídeos de cadeia média como agentes nefroprotetores |
| CN101903028B (zh) * | 2007-12-19 | 2013-06-05 | 普罗米蒂克生物科学公司 | 与吉西他滨组合用于治疗胰腺癌的中等链长脂肪酸、盐类及三酸甘油酯 |
| JP2011519373A (ja) | 2008-05-01 | 2011-07-07 | コンプレクザ インコーポレイテッド | ビニル置換脂肪酸 |
| EP2299997A4 (en) * | 2008-06-19 | 2012-01-11 | Univ Utah Res Found | USE OF NITRATED LIPIDS FOR THE TREATMENT OF SIDE EFFECTS OF TOXIC MEDICAL THERAPIES |
| US20140024713A1 (en) | 2008-06-19 | 2014-01-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
| KR101814186B1 (ko) | 2008-09-17 | 2018-03-14 | 키아스마 인코포레이티드 | 약제학적 조성물 및 연관된 투여방법 |
| EP2165713B1 (en) * | 2008-09-19 | 2012-11-14 | Nestec S.A. | Whey and thymus function |
| EP3045167A1 (en) | 2009-07-31 | 2016-07-20 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Keto fatty acids as anti-inflammatory agents |
| EP2483233A4 (en) | 2009-10-02 | 2013-08-14 | Complexa Inc | HETEROATOMA CONTAINING SUBSTITUTED FATTY ACIDS |
| EP2394636B1 (en) * | 2010-05-28 | 2014-03-19 | Novagali Pharma S.A. | Method for treating retinal conditions using an intraocular tamponade |
| WO2013028501A1 (en) | 2011-08-19 | 2013-02-28 | The University Of Utah Research Foundation | Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system |
| TWI572352B (zh) * | 2012-03-01 | 2017-03-01 | 波麥堤克藥學Ｓｍｔ有限公司 | 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法 |
| CN104411316B (zh) * | 2012-05-09 | 2018-05-01 | 坎泰克斯制药股份有限公司 | 骨髓抑制的治疗 |
| KR101621856B1 (ko) | 2013-08-19 | 2016-05-17 | 한국생명공학연구원 | 모노아세틸디아실글리세롤 화합물을 유효성분으로 함유하는 류마티스 관절염의 예방 또는 치료용 조성물 |
| JP6321886B2 (ja) * | 2014-05-15 | 2018-05-09 | エンジーケム ライフサイエンシーズ コーポレーションＥｎｚｙｃｈｅｍ Ｌｉｆｅｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ | 白血球減少症及び血小板減少症に対する治療方法 |
| WO2016126830A1 (en) | 2015-02-03 | 2016-08-11 | Chiasma Inc. | Method of treating diseases |
| US10052346B2 (en) | 2015-02-17 | 2018-08-21 | Cantex Pharmaceuticals, Inc. | Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids |
| PT3865484T (pt) | 2015-07-07 | 2024-01-30 | H Lundbeck As | Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas |
| WO2017059451A1 (en) | 2015-10-02 | 2017-04-06 | Complexa, Inc. | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
| US9808438B2 (en) * | 2015-11-09 | 2017-11-07 | Enzychem Lifesciences Corporation | Method for treating mucositis |
| BR112018071518A2 (pt) | 2016-04-22 | 2019-02-19 | Receptor Life Sciences, Inc. | compostos medicinais à base de planta de ação rápida e suplementos nutricionais |
| MX2018015188A (es) | 2016-06-08 | 2019-08-21 | Sunregen Healthcare Ag | Lipidos con un numero impar de atomos de carbono y su uso como una composicion farmaceutica o como un suplemento nutricional. |
| EA201892396A1 (ru) | 2016-12-02 | 2019-04-30 | Ресептор Лайф Сайенсиз, Инк. | Быстродействующие растительные лекарственные соединения и биологически активные добавки |
| CN107382710B (zh) * | 2017-08-19 | 2020-11-06 | 中国铁道科学研究院集团有限公司铁道建筑研究所 | 一种接枝抗氧剂分子的多元醇 |
| BR112020004023A2 (pt) * | 2017-09-12 | 2020-09-08 | Sunregen Healthcare Ag | uso de um composto e composição farmacêutica ou suplemento nutricional |
| CA3078549A1 (en) * | 2017-10-05 | 2019-04-11 | Receptor Holdings, Inc. | Rapid onset and extended action plant-based and synthetic cannabinoid formulations |
| JP2020536858A (ja) * | 2017-10-05 | 2020-12-17 | レセプター・ホールディングス・インコーポレイテッド | 改善されたバイオアベイラビリティーを有するハーブ組成物 |
| KR102054401B1 (ko) * | 2018-03-26 | 2019-12-10 | 주식회사 엔지켐생명과학 | 1,2-디아실글리세롤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역조절제 |
| CA3100988A1 (en) | 2018-05-25 | 2019-11-28 | Imara Inc. | Monohydrate and crystalline forms of 6-[(3s,4s)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7h-imidazo[1,5-a]pyrazin-8-one |
| CA3110680A1 (en) | 2018-08-31 | 2020-03-05 | Imara Inc. | Pde9 inhibitors for treating sickle cell disease |
| SG11202103011YA (en) | 2018-10-11 | 2021-04-29 | Basf As | Aromatic compounds and pharmaceutical uses thereof |
| EP3883595A4 (en) | 2018-11-19 | 2022-12-14 | Receptor Holdings, Inc. | N-ACYLATED FATTY AMINO ACIDS TO REDUCE ABSORPTION VARIABILITY IN CANNABINOID-BASED COMPOSITIONS |
| WO2021085144A1 (ja) * | 2019-10-31 | 2021-05-06 | 日本ゼオン株式会社 | 電気化学素子用機能層およびその製造方法、電気化学素子用機能層付きセパレータおよびその製造方法、並びに電気化学素子およびその製造方法 |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
| WO2023067501A1 (en) * | 2021-10-18 | 2023-04-27 | Enzychem Lifesciences Corporation | Compositions and methods for treating mucositis |
| US20250270471A1 (en) * | 2022-04-21 | 2025-08-28 | Merck Sharp & Dohme Llc | Process for preparing agglomerated crystalline medium-chain fatty acid sodium salts |
| WO2026013252A1 (en) * | 2024-07-12 | 2026-01-15 | Paoli Alessio | A mixture of mono-, di- and triglycerides of nonanoic acid for use in the treatment of muscle atrophy, sarcopenia and muscle-injury |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2002A (en) * | 1841-03-12 | Tor and planter for plowing | ||
| US2004A (en) * | 1841-03-12 | Improvement in the manner of constructing and propelling steam-vessels | ||
| US2006A (en) * | 1841-03-16 | Clamp for crimping leather | ||
| US2008A (en) * | 1841-03-18 | Gas-lamp eok conducting gas pkom ah elevated buhner to one below it | ||
| US2003A (en) * | 1841-03-12 | Improvement in horizontal windivhlls | ||
| US4528197A (en) * | 1983-01-26 | 1985-07-09 | Kabivitrum Ab | Controlled triglyceride nutrition for hypercatabolic mammals |
| US4703062A (en) * | 1984-01-16 | 1987-10-27 | Baxter Travenol Laboratories, Inc. | Parenteral nutrition with medium and long chain triglycerides |
| US4871768A (en) * | 1984-07-12 | 1989-10-03 | New England Deaconess Hospital Corporation | Dietary supplement utilizing ω-3/medium chain trigylceride mixtures |
| US4816440A (en) * | 1985-09-26 | 1989-03-28 | Cetus Corporation | Stable formulation of biologically active proteins for parenteral injection |
| US7307166B1 (en) * | 1987-10-28 | 2007-12-11 | Wellstat Therapeutics Corporation | Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis |
| US5011852A (en) * | 1988-07-25 | 1991-04-30 | Applied Analytical Industries, Inc. | Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs |
| JPH02134326A (ja) * | 1988-11-14 | 1990-05-23 | Snow Brand Milk Prod Co Ltd | 高度侵襲用経腸栄養剤 |
| JP3249147B2 (ja) * | 1990-06-01 | 2002-01-21 | キリン−アムジエン・インコーポレーテツド | 生理活性蛋白含有経口製剤 |
| JPH05506673A (ja) * | 1991-02-22 | 1993-09-30 | アムジエン・インコーポレーテツド | 迅速な創傷の治癒を促進するためのｇｍ―ｃｓｆ及びｇ―ｃｓｆの使用 |
| JP3132085B2 (ja) * | 1991-09-06 | 2001-02-05 | ウェルファイド株式会社 | 脂肪乳剤 |
| JPH05163160A (ja) * | 1991-12-13 | 1993-06-29 | Snow Brand Milk Prod Co Ltd | 免疫低下に伴う感染症の予防及び治療用栄養剤 |
| US5214035A (en) * | 1992-04-16 | 1993-05-25 | Hoechst-Roussel Agri-Vet Company | Thixotropic formulations |
| US5308832A (en) * | 1992-07-27 | 1994-05-03 | Abbott Laboratories | Nutritional product for persons having a neurological injury |
| US5318781A (en) * | 1993-04-06 | 1994-06-07 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
| US20010003739A1 (en) * | 1993-06-24 | 2001-06-14 | Astrazeneca Ab | Systemic administration of a therapeutic preparation |
| US5631219A (en) * | 1994-03-08 | 1997-05-20 | Somatogen, Inc. | Method of stimulating hematopoiesis with hemoglobin |
| WO1995030413A1 (en) * | 1994-05-10 | 1995-11-16 | The Kitasato Institute | Hematopoietic stem cell proliferation accelerator |
| US5470861A (en) * | 1994-08-04 | 1995-11-28 | Hoffmann-La Roche Inc. | Method of promoting hair growth |
| US5549905A (en) * | 1994-10-18 | 1996-08-27 | Clintec Nutrition Co. | Enternal composition for pediatric patients |
| JPH08208510A (ja) | 1994-11-03 | 1996-08-13 | F Hoffmann La Roche Ag | インターフェロン組成物 |
| GB9516268D0 (en) * | 1995-08-08 | 1995-10-11 | Danbiosyst Uk | Compositiion for enhanced uptake of polar drugs from the colon |
| US5733884A (en) * | 1995-11-07 | 1998-03-31 | Nestec Ltd. | Enteral formulation designed for optimized wound healing |
| AU701736B2 (en) * | 1995-11-28 | 1999-02-04 | B. Braun Melsungen Ag | Hydrolysis-optimized lipid emulsions and use thereof |
| AUPN933396A0 (en) * | 1996-04-17 | 1996-05-09 | Pfizer Pty Limited | Non-aqueuos oral-drench compositions containing avermectin compounds |
| US5851534A (en) * | 1996-05-03 | 1998-12-22 | Dynagen, Inc. | Methods for prevention and/or treatment of neutropenia |
| JPH10265380A (ja) | 1997-03-17 | 1998-10-06 | Bristol Myers Squibb Co | 抗ガン剤 |
| US6017531A (en) * | 1997-06-02 | 2000-01-25 | W. R. Grace & Co. | Hydrophilic composition containing protease produced by Vibrio |
| WO1999011242A1 (en) | 1997-09-04 | 1999-03-11 | Biozone Laboratories, Inc. | Oral liposomal delivery system |
| EP1032358B1 (en) * | 1997-11-19 | 2005-05-18 | Hercules Incorporated | Fluidized polymer suspensions of cationic polysaccharides in emollients and use thereof in preparing personal care compositions |
| WO1999026640A1 (en) * | 1997-11-20 | 1999-06-03 | Bukwang Pharm. Ind. Co., Ltd. | Pharmaceutical composition containing extracts of cervus nippon antlers having growth-stimulating activities of hematopoietic stem cells and megakaryocytes |
| US6326360B1 (en) | 1998-03-11 | 2001-12-04 | Grelan Pharmaceuticals Co., Ltd. | Bubbling enteric coated preparations |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| WO2001022937A1 (en) * | 1999-09-27 | 2001-04-05 | Sonus Pharmaceuticals, Inc. | Compositions of tocol-soluble therapeutics |
| US6835750B1 (en) * | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| AU2001264079A1 (en) | 2000-06-14 | 2001-12-24 | William Leslie Porter | Lipids for modulating immune response |
| US20030176500A1 (en) * | 2000-06-20 | 2003-09-18 | Koen Molly | Medium chain fatty acids applicable as antimicrobial agents |
| US6967028B2 (en) * | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
| IL142535A0 (en) | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
| JP5026655B2 (ja) * | 2001-04-18 | 2012-09-12 | プロメティック、バイオサイエンシーズ、インコーポレーテッド | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| US20040052836A1 (en) | 2002-09-13 | 2004-03-18 | Li Luk Chiu | Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life |
| ATE419846T1 (de) | 2003-02-07 | 2009-01-15 | Prometic Biosciences Inc | Fettsäuren mittlerer kettenlänge, glyceride und analoga als stimulatoren der erythropoiese |
| US6725510B1 (en) * | 2003-04-25 | 2004-04-27 | Almetta Clyburn | Inclining coffin |
| PT1648851E (pt) | 2003-07-25 | 2007-05-31 | Prometic Biosciences Inc | Praparação de sais metálicos de ácidos gordos de cadeia média |
| MX2007002727A (es) * | 2004-09-03 | 2008-03-04 | Prometic Biosciences Inc | Derivados de purinilo sustituidos con actividad inmunomoduladora y quimioprotectora, y su uso solos o con acidos grasos de longitud de cadena media o gliceridos. |
| US8071580B2 (en) * | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
-
2002
- 2002-04-18 JP JP2002580924A patent/JP5026655B2/ja not_active Expired - Lifetime
- 2002-04-18 DK DK07116425.5T patent/DK1900364T3/da active
- 2002-04-18 DE DE60223670T patent/DE60223670T2/de not_active Expired - Lifetime
- 2002-04-18 PT PT71164255T patent/PT1900364E/pt unknown
- 2002-04-18 ES ES07116425.5T patent/ES2439738T3/es not_active Expired - Lifetime
- 2002-04-18 EP EP02761857A patent/EP1385498B1/en not_active Expired - Lifetime
- 2002-04-18 PL PL366435A patent/PL223348B1/pl unknown
- 2002-04-18 IL IL15832202A patent/IL158322A0/xx active IP Right Grant
- 2002-04-18 WO PCT/CA2002/000535 patent/WO2002083120A2/en not_active Ceased
- 2002-04-18 ES ES02761857T patent/ES2295397T3/es not_active Expired - Lifetime
- 2002-04-18 KR KR10-2003-7013555A patent/KR20030096323A/ko not_active Ceased
- 2002-04-18 SK SK1277-2003A patent/SK12772003A3/sk unknown
- 2002-04-18 CN CNA028094263A patent/CN1633286A/zh active Pending
- 2002-04-18 CA CA2444463A patent/CA2444463C/en not_active Expired - Lifetime
- 2002-04-18 NZ NZ541140A patent/NZ541140A/en not_active IP Right Cessation
- 2002-04-18 SI SI200230655T patent/SI1385498T1/sl unknown
- 2002-04-18 BR BR0208984-0A patent/BR0208984A/pt not_active Application Discontinuation
- 2002-04-18 CA CA2763637A patent/CA2763637C/en not_active Expired - Lifetime
- 2002-04-18 DK DK02761857T patent/DK1385498T3/da active
- 2002-04-18 HU HU0303817A patent/HUP0303817A3/hu unknown
- 2002-04-18 AP APAP/P/2003/002888A patent/AP1740A/en active
- 2002-04-18 PL PL402948A patent/PL222876B1/pl unknown
- 2002-04-18 EE EEP200300510A patent/EE200300510A/xx unknown
- 2002-04-18 OA OA1200300273A patent/OA12506A/en unknown
- 2002-04-18 MX MXPA03009436A patent/MXPA03009436A/es active IP Right Grant
- 2002-04-18 EA EA200301131A patent/EA007322B1/ru not_active IP Right Cessation
- 2002-04-18 EP EP07116425.5A patent/EP1900364B1/en not_active Expired - Lifetime
- 2002-04-18 CZ CZ2003-2685A patent/CZ305273B6/cs not_active IP Right Cessation
- 2002-04-18 PT PT02761857T patent/PT1385498E/pt unknown
- 2002-04-18 AU AU2002308456A patent/AU2002308456B2/en not_active Expired
- 2002-04-18 NZ NZ528690A patent/NZ528690A/en not_active IP Right Cessation
- 2002-04-18 US US10/475,266 patent/US7745488B2/en not_active Expired - Lifetime
-
2003
- 2003-07-08 TN TNPCT/CA2002/000535A patent/TNSN03089A1/en unknown
- 2003-10-06 ZA ZA200307778A patent/ZA200307778B/en unknown
- 2003-10-09 IL IL158322A patent/IL158322A/en unknown
- 2003-10-17 BG BG108280A patent/BG66418B1/bg unknown
- 2003-10-17 NO NO20034644A patent/NO335105B1/no not_active IP Right Cessation
-
2006
- 2006-03-21 AU AU2006201163A patent/AU2006201163B2/en not_active Expired
-
2007
- 2007-12-12 CY CY20071101574T patent/CY1107081T1/el unknown
-
2008
- 2008-11-10 IL IL195200A patent/IL195200A/en active IP Right Grant
-
2009
- 2009-11-30 JP JP2009272679A patent/JP5657879B2/ja not_active Expired - Lifetime
-
2010
- 2010-06-11 US US12/814,028 patent/US8487001B2/en not_active Expired - Fee Related
-
2014
- 2014-08-15 JP JP2014165557A patent/JP6420089B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010053135A5 (https=) | ||
| JP6212765B2 (ja) | 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤 | |
| JP2012526850A5 (https=) | ||
| EP2275107A3 (en) | Combinations for the treatment of diseases involving cell proliferation | |
| JP2007045839A5 (https=) | ||
| RU2016149232A (ru) | Способы лечения лейкопении и тромбоцитопении | |
| RU2014144498A (ru) | Композиции для борьбы с клещами варроа у пчел | |
| CA2455559A1 (en) | Methods to mobilize progenitor/stem cells | |
| RU2018120318A (ru) | ИМИДАЗО[4,5-c]ХИНОЛИН-2-ОНОВЫЕ СОЕДИНЕНИЯ И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ РАКА | |
| JP2011530545A5 (https=) | ||
| RU2020107416A (ru) | Комбинация, содержащая палбоциклиб и 6-(2,4-дихлорфенил)-5-[4-[(3s)-1-(3-фторпропил)пиррролидин-3-ил]-8,9-дигидро-7h-бензо[7]аннулен-2-карбоновую кислоту, и ее применение для лечения рака | |
| CN1345242A (zh) | 治疗白血病的方法 | |
| Bolwell et al. | Delayed G-CSF after autologous progenitor cell transplantation: a prospective randomized trial | |
| RU2014124171A (ru) | Лекарственное средство для терапевтического лечения и/или улучшения состояния при сепсисе | |
| JP2009510165A5 (https=) | ||
| CN107137417A (zh) | 一种用于治疗恶病质的药物组合物及其应用 | |
| CN114732807A (zh) | 米托蒽醌在制备预防或治疗急性移植物抗宿主病药物中的应用 | |
| CN104415332A (zh) | 异硫氰酸酯类化合物与激酶抑制剂类药物在癌症治疗中的联合应用 | |
| CN103251741A (zh) | 一种治疗猪弓形虫病的中药组合物及其制备方法和应用 | |
| JP5976923B2 (ja) | イリノテカン塩酸塩水和物を含有する抗腫瘍剤 | |
| CN104622874B (zh) | Ccr4拮抗剂在抑制癌生长及转移中的应用 | |
| RU2012114023A (ru) | Способ стимуляции эндогенной продукции цитокинов и гемопоэтических факторов | |
| CN104117064A (zh) | 异硫氰酸酯类化合物与激素类药物的联合应用 | |
| WO2011052919A3 (ko) | 신규 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 면역보조용 약학적 조성물 | |
| TWI446902B (zh) | 一種化合物之用途, 其係用於製備治療敗血性休克之藥物 |