PT3865484T - Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas - Google Patents

Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas

Info

Publication number
PT3865484T
PT3865484T PT202178331T PT20217833T PT3865484T PT 3865484 T PT3865484 T PT 3865484T PT 202178331 T PT202178331 T PT 202178331T PT 20217833 T PT20217833 T PT 20217833T PT 3865484 T PT3865484 T PT 3865484T
Authority
PT
Portugal
Prior art keywords
treatment
pde9 inhibitor
peripheral diseases
backbone
imidazo
Prior art date
Application number
PT202178331T
Other languages
English (en)
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of PT3865484T publication Critical patent/PT3865484T/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
PT202178331T 2015-07-07 2016-07-06 Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas PT3865484T (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201500393 2015-07-07
DKPA201500407 2015-07-10
DKPA201600209 2016-04-07

Publications (1)

Publication Number Publication Date
PT3865484T true PT3865484T (pt) 2024-01-30

Family

ID=56345156

Family Applications (1)

Application Number Title Priority Date Filing Date
PT202178331T PT3865484T (pt) 2015-07-07 2016-07-06 Inibidor da pde9 com esqueleto de imidazo pirazinona para tratamento de doenças periféricas

Country Status (21)

Country Link
US (4) US10513524B2 (pt)
EP (3) EP4335497A3 (pt)
CN (2) CN107810187B (pt)
AU (2) AU2016289856B2 (pt)
BR (1) BR112018000254A2 (pt)
CA (1) CA2990521C (pt)
DK (2) DK3303339T3 (pt)
ES (1) ES2869939T3 (pt)
FI (1) FI3865484T3 (pt)
HK (1) HK1249903A1 (pt)
HR (2) HRP20240082T1 (pt)
HU (1) HUE053968T2 (pt)
IL (2) IL280619B2 (pt)
LT (1) LT3865484T (pt)
MX (1) MX2018000283A (pt)
PL (1) PL3865484T3 (pt)
PT (1) PT3865484T (pt)
SI (1) SI3303339T1 (pt)
TN (1) TN2017000507A1 (pt)
WO (1) WO2017005786A1 (pt)
ZA (1) ZA201708341B (pt)

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DK3303339T3 (da) 2015-07-07 2021-04-12 H Lundbeck As Pde9-inhibitorer med imidazotriazinonskelet og imidazopyrazinonskelet til behandling af perifere sygdomme
AU2017292650A1 (en) * 2016-07-06 2018-12-13 H. Lundbeck A/S PDE9 inhibitors for treatment of peripheral diseases
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WO2018224455A1 (en) 2017-06-07 2018-12-13 Basf Se Substituted cyclopropyl derivatives
WO2018234488A1 (en) 2017-06-23 2018-12-27 Basf Se SUBSTITUTED CYCLOPROPYL DERIVATIVES
JP2021526134A (ja) * 2018-05-25 2021-09-30 イマラ インク． ６−［（３Ｓ，４Ｓ）−４−メチル−ｌ−（ピリミジン−２−イルメチル）ピロリジン−３−イル］−３−テトラヒドロピラン−４−イル−７Ｈ−イミダゾ［ｌ，５−Ａ］ピラジン−８−オンの一水和物および結晶形態
KR20210053948A (ko) * 2018-08-31 2021-05-12 이마라 인크. 겸상 세포 질환의 치료를 위한 pde9 억제제
CA3136128A1 (en) * 2019-04-05 2020-10-08 Imara Inc. Pde9 inhibitors for treating sickle cell disease
WO2020227399A1 (en) * 2019-05-07 2020-11-12 Imara Inc. Pde9 inhibitors for treating thalassemia
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CN112552339A (zh) * 2020-12-10 2021-03-26 安徽昊帆生物有限公司 一种o-二苯基磷酰羟胺的制备方法
AU2022311952A1 (en) * 2021-07-13 2024-01-25 Relay Therapeutics, Inc. PI3Kα INHIBITORS AND METHODS OF USE THEREOF
CN115448864B (zh) * 2022-08-26 2023-12-22 上海方予健康医药科技有限公司 3-氟-3-（1-羟乙基）吡咯烷-1-羧酸叔丁酯的制备方法

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