CN1633286A - 作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物 - Google Patents

作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物 Download PDF

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Publication number
CN1633286A
CN1633286A CNA028094263A CN02809426A CN1633286A CN 1633286 A CN1633286 A CN 1633286A CN A028094263 A CNA028094263 A CN A028094263A CN 02809426 A CN02809426 A CN 02809426A CN 1633286 A CN1633286 A CN 1633286A
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patient
neutropenia
treats
mct
general formula
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Chinese (zh)
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L·加尼翁
J·巴拉比
P·劳林
C·彭尼
B·扎卡里
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Prometic Biosciences Inc
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Prometic Biosciences Inc
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    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNA028094263A 2001-04-18 2002-04-18 作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物 Pending CN1633286A (zh)

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US28445801P 2001-04-18 2001-04-18
US60/284,458 2001-04-18

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CN1633286A true CN1633286A (zh) 2005-06-29

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CNA028094263A Pending CN1633286A (zh) 2001-04-18 2002-04-18 作为中性白细胞存活和激活因子的中链长度的脂肪酸、甘油酯和类似物

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US (2) US7745488B2 (https=)
EP (2) EP1385498B1 (https=)
JP (3) JP5026655B2 (https=)
KR (1) KR20030096323A (https=)
CN (1) CN1633286A (https=)
AP (1) AP1740A (https=)
AU (2) AU2002308456B2 (https=)
BG (1) BG66418B1 (https=)
BR (1) BR0208984A (https=)
CA (2) CA2763637C (https=)
CY (1) CY1107081T1 (https=)
CZ (1) CZ305273B6 (https=)
DE (1) DE60223670T2 (https=)
DK (2) DK1900364T3 (https=)
EA (1) EA007322B1 (https=)
EE (1) EE200300510A (https=)
ES (2) ES2439738T3 (https=)
HU (1) HUP0303817A3 (https=)
IL (3) IL158322A0 (https=)
MX (1) MXPA03009436A (https=)
NO (1) NO335105B1 (https=)
NZ (2) NZ541140A (https=)
OA (1) OA12506A (https=)
PL (2) PL223348B1 (https=)
PT (2) PT1385498E (https=)
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101903028A (zh) * 2007-12-19 2010-12-01 普罗米蒂克生物科学公司 与吉西他滨组合用于治疗胰腺癌的中等链长脂肪酸、盐类及三酸甘油酯
CN102099024B (zh) * 2008-06-19 2015-11-25 犹他大学研究基金会 硝化脂质在毒性医疗疗法的副作用的治疗上的用途
CN106535887A (zh) * 2014-05-15 2017-03-22 株式会社Enzychem生命科学 治疗白细胞减少症和血小板减少症的方法
CN111902389A (zh) * 2018-03-26 2020-11-06 株式会社Enzychem生命科学 1,2-二酰基甘油化合物、其制备方法和含有其作为活性成分的免疫调节剂

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IL158322A0 (en) 2001-04-18 2004-05-12 Prometic Biosciences Inc Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
DK1592416T3 (da) * 2003-02-07 2009-04-20 Prometic Biosciences Inc Fedtsyrer med middel kædelængde, glycerider og analoger som stimulatorer af erythropoiesis
JP5214880B2 (ja) 2003-07-25 2013-06-19 プロメティック、バイオサイエンシーズ、インコーポレーテッド 中鎖脂肪酸の金属塩の製造
US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
US8241670B2 (en) * 2004-04-15 2012-08-14 Chiasma Inc. Compositions capable of facilitating penetration across a biological barrier
KR20070063507A (ko) * 2004-09-03 2007-06-19 프로메틱 바이오사이언시즈 인코포레이티드 면역조절작용과 화학방어활성을 가진 치환된 퓨리닐 유도체및 단독 또는 중쇄 길이 지방산이나 글리세리드와의 혼합사용
US8071580B2 (en) 2004-10-01 2011-12-06 Prometic Biosciences Inc. Medium-chain length fatty alcohols as stimulators of hematopoiesis
MX2007003967A (es) * 2004-10-01 2008-03-04 Prometic Biosciences Inc Alcoholes grasos con longitud de cadena media como estimuladores de hematopoyesis.
AU2006217544B8 (en) * 2005-02-28 2012-04-05 Alphabeta Ab Compounds for reducing aggregation of amyloid beta-peptide
EP2669368B1 (en) * 2006-05-17 2016-08-03 Cognate Therapeutics, Inc. Isolation and purification of hematopoietic stem cells from post-liposuction lipoaspirates
EP2679224A1 (en) 2007-08-01 2014-01-01 University of Pittsburgh of the Commonwealth System of Higher Education Nitro oleic acid modulation of type II diabetes
CN101878028A (zh) 2007-11-02 2010-11-03 普罗米蒂克生物科学公司 作为肾保护剂的中链长度脂肪酸和甘油酯
CN102083787A (zh) 2008-05-01 2011-06-01 康普雷克萨公司 乙烯基取代的脂肪酸
US20140024713A1 (en) 2008-06-19 2014-01-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
CN102176900B (zh) 2008-09-17 2017-09-26 克艾思马有限公司 药物组合物和相关的给药方法
EP2165713B1 (en) * 2008-09-19 2012-11-14 Nestec S.A. Whey and thymus function
EP2459189A4 (en) 2009-07-31 2013-01-16 Univ Pittsburgh FATTY ACIDS AS ANTI-INFLAMMATORY AGENTS
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