|
DE1420015B1
(de)
|
1959-10-16 |
1971-08-26 |
Boehringer Sohn Ingelheim |
2'-Hydroxy-5,9-dimethyl-6,7-benzomorphane
|
|
GB1202148A
(en)
|
1968-03-06 |
1970-08-12 |
Sankyo Co |
Pharmaceutical compositions
|
|
US3854480A
(en)
|
1969-04-01 |
1974-12-17 |
Alza Corp |
Drug-delivery system
|
|
US3884916A
(en)
|
1971-03-30 |
1975-05-20 |
Janssen Pharmaceutica Nv |
2,2-Diaryl-4-(4-aryl-4-hydroxy-piperidino)-butyramides
|
|
US3714159A
(en)
|
1971-03-30 |
1973-01-30 |
Janssen Pharmaceutica Nv |
2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
|
|
US4326074A
(en)
|
1972-09-22 |
1982-04-20 |
William H. Rorer, Inc. |
Amidinoureas
|
|
US4025652A
(en)
|
1975-03-31 |
1977-05-24 |
William H. Rorer, Inc. |
Amidinoureas
|
|
US3937801A
(en)
|
1973-07-10 |
1976-02-10 |
American Home Products Corporation |
Reducing the incidence of gastrointestinal side effects during the treatment of inflammatory conditions with antiinflammatory drugs
|
|
US4060635A
(en)
|
1975-03-31 |
1977-11-29 |
William H. Rorer, Inc. |
Amidinoureas for treating diarrhea
|
|
US4203920A
(en)
|
1975-03-31 |
1980-05-20 |
William H. Rorer, Inc. |
Amidinoureas
|
|
US4072686A
(en)
|
1975-04-16 |
1978-02-07 |
G. D. Searle & Co. |
1-(3,3,3-Triarylalkyl)-4-phenyl-piperidinealkanols
|
|
US4066654A
(en)
|
1975-04-16 |
1978-01-03 |
G. D. Searle & Co. |
1-triarylalkyl-4-phenyl-4-piperidine carboxylic acids and derivatives
|
|
US3996214A
(en)
|
1976-02-23 |
1976-12-07 |
G. D. Searle & Co. |
5-(1,1-Diphenyl-4-(cyclic amino) but-2-trans-en-1-yl)-2-alkyl-1,3,4-oxadiazoles and intermediates thereto
|
|
US4013668A
(en)
|
1976-03-10 |
1977-03-22 |
G. D. Searle & Co. |
5-(1,1-diphenyl-3-(5- or 6-hydroxy-2-azabicyclo(2.2.2)oct-2-yl)propyl)-2-alkyl-1,3,4-oxadiazoles and related compounds
|
|
US4012393A
(en)
|
1976-03-22 |
1977-03-15 |
G. D. Searle & Co. |
2-[5-(CYCLIC AMINO) ETHYL-10,11-DIHYDRO-5H-dibenzo[a,d]-cyclohepten-5- yl]-5
|
|
US4115400A
(en)
|
1976-05-27 |
1978-09-19 |
Eli Lilly And Company |
1-Azoniabicyclo[3.1.0]hexanes
|
|
GB1593191A
(en)
|
1977-03-23 |
1981-07-15 |
Reckitt & Colmann Prod Ltd |
Derivatives of morphine
|
|
US4125531A
(en)
|
1977-04-18 |
1978-11-14 |
G. D. Searle & Co. |
2-Substituted-1-azabicyclo[2.2.2]octanes
|
|
US4069223A
(en)
|
1977-05-02 |
1978-01-17 |
G. D. Searle & Co. |
4-Aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and derivatives thereof
|
|
US4116963A
(en)
|
1977-05-23 |
1978-09-26 |
G.D. Searle & Co. |
3,3,3-triarylalkyl-4-phenylalkyl-4-hydroxy piperidines and related compounds
|
|
US4194045A
(en)
|
1977-12-27 |
1980-03-18 |
G. D. Searle & Co. |
1-(3,3-Diaryl-3-oxadiazolalkyl)-4-phenyl-4-piperidinomethanols and related compounds
|
|
IT1096665B
(it)
|
1978-06-14 |
1985-08-26 |
Tecnofarmaci Spa |
Composizione farmaceutica per la terapia di stati di frigidita' ed impotenza
|
|
US4176186A
(en)
|
1978-07-28 |
1979-11-27 |
Boehringer Ingelheim Gmbh |
Quaternary derivatives of noroxymorphone which relieve intestinal immobility
|
|
JPS5535031A
(en)
|
1978-09-04 |
1980-03-11 |
Shin Etsu Chem Co Ltd |
Enteric coating composition
|
|
US4311833A
(en)
|
1979-03-06 |
1982-01-19 |
Daicel Chemical Industries Ltd. |
Process for preparing ethylcarboxymethylcellulose
|
|
US4277605A
(en)
|
1980-03-07 |
1981-07-07 |
Bristol-Myers Company |
Chemical compounds
|
|
US4322426A
(en)
|
1980-04-28 |
1982-03-30 |
E. I. Du Pont De Nemours And Company |
17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
|
|
US4675189A
(en)
|
1980-11-18 |
1987-06-23 |
Syntex (U.S.A.) Inc. |
Microencapsulation of water soluble active polypeptides
|
|
US4466968A
(en)
|
1980-11-24 |
1984-08-21 |
Dermall, Ltd. |
Method for prophylaxis or treatment of emesis and nausea
|
|
US4427676A
(en)
|
1980-12-19 |
1984-01-24 |
John Wyeth & Brother Ltd. |
Thiomorpholine derivatives
|
|
US4377568A
(en)
|
1981-08-12 |
1983-03-22 |
Merck Sharp & Dohme (I.A.) Corp. |
Preparation of aqueous alcoholic dispersions of pH sensitive polymers and plasticizing agents and a method of enteric coating dosage forms using same
|
|
DK150008C
(da)
|
1981-11-20 |
1987-05-25 |
Benzon As Alfred |
Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
|
|
US4987136A
(en)
|
1982-03-16 |
1991-01-22 |
The Rockefeller University |
Method for controlling gastrointestinal dysmotility
|
|
US4870084A
(en)
|
1982-03-16 |
1989-09-26 |
Pfizer Inc. |
Bicyclic benzo fused pyran compounds used for nausea treatment and prevention
|
|
DE3381877D1
(de)
|
1982-03-16 |
1990-10-18 |
Univ Rockefeller |
Verwendung von opium antagonisten zur herstellung von arzneimitteln zur behebung gastro-intestinaler stoerungen.
|
|
US4430327A
(en)
|
1982-05-18 |
1984-02-07 |
Eli Lilly And Company |
Method for treating pregnant females for pain and anxiety
|
|
US4457907A
(en)
|
1982-08-05 |
1984-07-03 |
Clear Lake Development Group |
Composition and method for protecting a therapeutic drug
|
|
US4533739A
(en)
|
1982-10-12 |
1985-08-06 |
G. D. Searle & Co. |
2-[(Aminophenyl and amidophenyl)amino]-1-azacycloalkanes having antidiarrheal activity
|
|
US4518433A
(en)
|
1982-11-08 |
1985-05-21 |
Fmc Corporation |
Enteric coating for pharmaceutical dosage forms
|
|
US4452775A
(en)
|
1982-12-03 |
1984-06-05 |
Syntex (U.S.A.) Inc. |
Cholesterol matrix delivery system for sustained release of macromolecules
|
|
JPS601128A
(ja)
|
1983-06-15 |
1985-01-07 |
Shionogi & Co Ltd |
作用持続型セフアクロル製剤
|
|
US4462839A
(en)
|
1983-06-16 |
1984-07-31 |
Fmc Corporation |
Enteric coating for pharmaceutical dosage forms
|
|
US4556552A
(en)
|
1983-09-19 |
1985-12-03 |
Colorcon, Inc. |
Enteric film-coating compositions
|
|
DE3474511D1
(en)
|
1983-11-01 |
1988-11-17 |
Terumo Corp |
Pharmaceutical composition containing urokinase
|
|
US5266574A
(en)
|
1984-04-09 |
1993-11-30 |
Ian S. Zagon |
Growth regulation and related applications of opioid antagonists
|
|
US4689332A
(en)
|
1984-04-09 |
1987-08-25 |
Research Corporation |
Growth regulation and related applications of opioid antagonists
|
|
US4666716A
(en)
|
1984-09-04 |
1987-05-19 |
Richardson-Vicks Inc. |
Antidiarrheal compositions and use thereof
|
|
JPS6229515A
(ja)
|
1985-07-30 |
1987-02-07 |
Shinjiro Tsuji |
硬カプセル剤のフイルムコ−テイング方法
|
|
JPH0676314B2
(ja)
|
1985-09-30 |
1994-09-28 |
花王株式会社 |
坐剤基剤及び坐剤
|
|
US4824853A
(en)
|
1985-10-11 |
1989-04-25 |
Janssen Pharmaceutica N.V. |
α,α-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide, N-oxides and method of treating diarrhea
|
|
US4730048A
(en)
|
1985-12-12 |
1988-03-08 |
Regents Of The University Of Minnesota |
Gut-selective opiates
|
|
US4806556A
(en)
|
1985-12-12 |
1989-02-21 |
Regents Of The University Of Minnesota |
Gut-selective opiates
|
|
EP0306575B1
(en)
|
1987-09-10 |
1992-07-29 |
The University Of Chicago |
Quaternary derivatives of noroxymorphone which relieve nausea and emesis
|
|
US4719215A
(en)
|
1986-03-07 |
1988-01-12 |
University Of Chicago |
Quaternary derivatives of noroxymorphone which relieve nausea and emesis
|
|
US4861781A
(en)
|
1986-03-07 |
1989-08-29 |
The University Of Chicago |
Quaternary derivatives of noroxymorphone which relieve nausea and emesis
|
|
CA1297218C
(en)
|
1986-03-14 |
1992-03-10 |
Edward David Weil |
Thermally stable diphosphonate-type flame retardant additive for plastics
|
|
DE3609073C2
(de)
|
1986-03-18 |
1995-08-10 |
Hans J Prof Dr Rer Nat Schmitt |
Meßeinrichtung zur nichtinvasiven Feststellung peripherer Abfluß- und Durchflußstörungen in menschlichen Extremitäten
|
|
US4990521A
(en)
|
1986-07-03 |
1991-02-05 |
Janssen Pharmaceutica |
4-(aroylamino)piperidine-butanimide derivatives
|
|
DE3777658D1
(de)
|
1986-08-28 |
1992-04-23 |
Enzacor Pty Ltd |
Tierwachstumserreger.
|
|
US5597564A
(en)
|
1986-08-28 |
1997-01-28 |
Enzacor Properties Limited |
Method of administering a microgranular preparation to the intestinal region of animals
|
|
US4888346A
(en)
|
1986-10-07 |
1989-12-19 |
Bernard Bihari |
Method for the treatment of persons infected with HTLV-III (AIDS) virus
|
|
US4765978A
(en)
|
1986-12-16 |
1988-08-23 |
Schering Corporation |
Novel vaginal suppository
|
|
FR2609632B1
(fr)
|
1987-01-21 |
1991-03-29 |
Shelly Marc |
Nouvelle application therapeutique de la 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinon-6-one et les compositions pharmaceutiques destinees a cet usage
|
|
NL8700842A
(enExample)
|
1987-04-10 |
1988-11-01 |
Duphar Int Res |
|
|
US4891379A
(en)
|
1987-04-16 |
1990-01-02 |
Kabushiki Kaisha Kobe Seikosho |
Piperidine opioid antagonists
|
|
IL83086A
(en)
|
1987-07-06 |
1991-03-10 |
Teva Pharma |
Stable,injectable solutions of vincristine salts
|
|
US4857833A
(en)
|
1987-08-27 |
1989-08-15 |
Teradyne, Inc. |
Diagnosis of faults on circuit board
|
|
CA1315689C
(en)
|
1987-09-03 |
1993-04-06 |
Leon I. Goldberg |
Quarternary derivatives of noroxymorphone which relieve nausea and emesis
|
|
DE3744053A1
(de)
|
1987-12-21 |
1989-07-13 |
Schering Ag |
Fungizides mittel mit synergistischer wirkung
|
|
US4912114A
(en)
|
1988-03-18 |
1990-03-27 |
Sandoz Ltd. |
Morphinan derivatives
|
|
ES2085865T3
(es)
|
1988-06-30 |
1996-06-16 |
Astra Ab |
Analogos de dermorfina, sus metodos de preparacion, composiciones farmaceuticas, y metodos de tratamiento terapeutico que los emplean.
|
|
JPH0653683B2
(ja)
|
1988-07-14 |
1994-07-20 |
ザ ロックフェラー ユニバーシティ |
慢性痛あるいは慢性咳を治療する経口用組成物
|
|
EP0352361A1
(en)
|
1988-07-29 |
1990-01-31 |
The Rockefeller University |
Method of treating patients suffering from chronic pain or chronic cough
|
|
US4999342A
(en)
|
1988-08-16 |
1991-03-12 |
Ortho Pharmaceutical Corporation |
Long lasting contraceptive suppository composition and methods of use
|
|
US4863928A
(en)
|
1989-01-04 |
1989-09-05 |
Baker Cummins Pharmaceuticals, Inc. |
Method of treatment for arthritic and inflammatory diseases
|
|
US5102887A
(en)
|
1989-02-17 |
1992-04-07 |
Arch Development Corporation |
Method for reducing emesis and nausea induced by the administration of an emesis causing agent
|
|
US5116868A
(en)
|
1989-05-03 |
1992-05-26 |
The Johns Hopkins University |
Effective ophthalmic irrigation solution
|
|
US5133974A
(en)
|
1989-05-05 |
1992-07-28 |
Kv Pharmaceutical Company |
Extended release pharmaceutical formulations
|
|
US4965269A
(en)
|
1989-12-20 |
1990-10-23 |
Ab Hassle |
Therapeutically active chloro substituted benzimidazoles
|
|
US5236947A
(en)
|
1990-02-28 |
1993-08-17 |
Jouveinal S.A. |
Propanamines, their pharmacological properties and their application as an antidiarrheal
|
|
JPH0813748B2
(ja)
|
1990-04-23 |
1996-02-14 |
帝國製薬株式会社 |
大腸崩壊性ポリペプチド系経口製剤
|
|
KR970005839B1
(ko)
|
1990-05-11 |
1997-04-21 |
화이자 인코포레이티드 |
상승 치료효과를 얻기 위한 조성물 및 방법
|
|
US5780012A
(en)
|
1990-06-21 |
1998-07-14 |
Huland; Edith |
Method for reducing lung afflictions by inhalation of cytokine solutions
|
|
JP3160862B2
(ja)
|
1990-11-15 |
2001-04-25 |
雪印乳業株式会社 |
骨強化食品、飼料及び医薬
|
|
JPH04230625A
(ja)
|
1990-12-27 |
1992-08-19 |
Standard Chem & Pharmaceut Corp Ltd |
噴霧乾燥したジクロフェナクナトリウムを含み腸溶性の被覆を有するマイクロカプセルからなる微分散した錠剤組成物の製造方法
|
|
EP0573565B1
(en)
|
1991-02-25 |
2000-07-19 |
Trustees Of Boston University |
Opiate receptor antagonist modulates hyperkinetic movement disorder
|
|
CA2064373C
(en)
|
1991-03-29 |
2005-08-23 |
Buddy Eugene Cantrell |
Piperidine derivatives
|
|
US5159081A
(en)
|
1991-03-29 |
1992-10-27 |
Eli Lilly And Company |
Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
|
|
US5250542A
(en)
|
1991-03-29 |
1993-10-05 |
Eli Lilly And Company |
Peripherally selective piperidine carboxylate opioid antagonists
|
|
US5270328A
(en)
|
1991-03-29 |
1993-12-14 |
Eli Lilly And Company |
Peripherally selective piperidine opioid antagonists
|
|
US5220017A
(en)
|
1991-04-10 |
1993-06-15 |
Merck & Co., Inc. |
Cholecystokinin antagonists
|
|
CA2110899C
(en)
|
1991-06-21 |
2006-08-08 |
Jacob G. Michael |
Orally administrable therapeutic proteins and method of making
|
|
US5407686A
(en)
|
1991-11-27 |
1995-04-18 |
Sidmak Laboratories, Inc. |
Sustained release composition for oral administration of active ingredient
|
|
US5614219A
(en)
|
1991-12-05 |
1997-03-25 |
Alfatec-Pharma Gmbh |
Oral administration form for peptide pharmaceutical substances, in particular insulin
|
|
US5256154A
(en)
|
1992-01-31 |
1993-10-26 |
Sterling Winthrop, Inc. |
Pre-filled plastic syringes and containers and method of terminal sterilization thereof
|
|
JPH05213763A
(ja)
|
1992-02-10 |
1993-08-24 |
Sanwa Kagaku Kenkyusho Co Ltd |
易吸収活性化カルシウム製剤
|
|
WO1993020826A1
(fr)
|
1992-04-10 |
1993-10-28 |
Vsesojuzny Nauchno-Issledovatelsky Institut Meditsinskikh Polimerov |
Composition pharmaceutique
|
|
US5686072A
(en)
|
1992-06-17 |
1997-11-11 |
Board Of Regents, The University Of Texas |
Epitope-specific monoclonal antibodies and immunotoxins and uses thereof
|
|
US5472943A
(en)
|
1992-09-21 |
1995-12-05 |
Albert Einstein College Of Medicine Of Yeshiva University, |
Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other opioid agonists
|
|
US6096756A
(en)
|
1992-09-21 |
2000-08-01 |
Albert Einstein College Of Medicine Of Yeshiva University |
Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
|
|
USRE36547E
(en)
|
1992-09-21 |
2000-02-01 |
Albert Einstein College Of Medicine Of Yeshiva University |
Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists
|
|
US5512578A
(en)
|
1992-09-21 |
1996-04-30 |
Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University |
Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opiod agonists
|
|
US5580876A
(en)
|
1992-09-21 |
1996-12-03 |
Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University |
Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
|
|
AU5171293A
(en)
|
1992-10-14 |
1994-05-09 |
Regents Of The University Of Colorado, The |
Ion-pairing of drugs for improved efficacy and delivery
|
|
GB9221707D0
(en)
*
|
1992-10-15 |
1992-12-02 |
Smithkline Beecham Plc |
Pharmaceutical composition
|
|
DK1167384T3
(da)
|
1992-10-28 |
2007-04-10 |
Genentech Inc |
Vaskular endotheliel cellevækstfaktor antagonister
|
|
SG52402A1
(en)
|
1992-12-22 |
1998-09-28 |
Univ Cincinnati |
Oral administration of immunologically active biomolecules and other therapeutic proteins
|
|
DE4303214A1
(de)
|
1993-02-04 |
1994-08-11 |
Wolfgang Marks |
Behandlung von Erkrankungen viraler, viroidaler oder onkogener Genese durch Steroid-Saponine oder deren Aglykone
|
|
US5585348A
(en)
|
1993-02-10 |
1996-12-17 |
Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University |
Use of excitatory opioid receptor antagonists to prevent growth factor-induced hyperalgesia
|
|
US5656290A
(en)
|
1993-02-26 |
1997-08-12 |
The Procter & Gamble Company |
Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
|
|
US5391372A
(en)
|
1993-06-28 |
1995-02-21 |
Campbell; Elizabeth |
Methods of treating colic and founder in horses
|
|
NZ268969A
(en)
|
1993-07-23 |
1997-06-24 |
Toray Industries |
Morphinan derivatives and pharmaceutical compositions
|
|
US5358970A
(en)
*
|
1993-08-12 |
1994-10-25 |
Burroughs Wellcome Co. |
Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
|
|
GB2281205A
(en)
|
1993-08-24 |
1995-03-01 |
Euro Celtique Sa |
Oral opioid analgesic
|
|
SE9303744D0
(sv)
|
1993-11-12 |
1993-11-12 |
Astra Ab |
Pharmaceutical emulsion
|
|
US5434171A
(en)
|
1993-12-08 |
1995-07-18 |
Eli Lilly And Company |
Preparation of 3,4,4-trisubstituted-piperidinyl-N-alkylcarboxylates and intermediates
|
|
US6190691B1
(en)
|
1994-04-12 |
2001-02-20 |
Adolor Corporation |
Methods for treating inflammatory conditions
|
|
EP0758403B1
(en)
|
1994-05-05 |
1998-06-24 |
Beckman Instruments, Inc. |
Oligonucleotide repeat arrays
|
|
IT1269826B
(it)
|
1994-05-24 |
1997-04-15 |
Paolo Minoia |
Uso di antagonisti degli oppiacei e di sali di calcio per la preparazione di medicamenti per il trattamento di forme patologiche endorfino-mediate
|
|
US5536507A
(en)
|
1994-06-24 |
1996-07-16 |
Bristol-Myers Squibb Company |
Colonic drug delivery system
|
|
US5866154A
(en)
*
|
1994-10-07 |
1999-02-02 |
The Dupont Merck Pharmaceutical Company |
Stabilized naloxone formulations
|
|
US5614222A
(en)
|
1994-10-25 |
1997-03-25 |
Kaplan; Milton R. |
Stable aqueous drug suspensions and methods for preparation thereof
|
|
US5965161A
(en)
|
1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
|
|
US5578725A
(en)
|
1995-01-30 |
1996-11-26 |
Regents Of The University Of Minnesota |
Delta opioid receptor antagonists
|
|
ES2094694B1
(es)
|
1995-02-01 |
1997-12-16 |
Esteve Quimica Sa |
Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
|
|
US6096763A
(en)
|
1995-02-23 |
2000-08-01 |
Merck & Co., Inc. |
α1a adrenergic receptor antagonists
|
|
US6025154A
(en)
|
1995-06-06 |
2000-02-15 |
Human Genome Sciences, Inc. |
Polynucleotides encoding human G-protein chemokine receptor HDGNR10
|
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
|
US5821219A
(en)
|
1995-08-11 |
1998-10-13 |
Oregon Health Sciences University |
Opioid antagonists and methods of their use
|
|
GB9517001D0
(en)
|
1995-08-18 |
1995-10-18 |
Denny William |
Enediyne compounds
|
|
US5804595A
(en)
|
1995-12-05 |
1998-09-08 |
Regents Of The University Of Minnesota |
Kappa opioid receptor agonists
|
|
EP0780372B3
(en)
|
1995-12-21 |
2013-05-22 |
Syngenta Participations AG |
3-Amino-2-mercaptobenzoic acid derivatives and processes for their preparation
|
|
EP0977558B1
(en)
|
1996-02-15 |
2003-10-01 |
Janssen Pharmaceutica N.V. |
Use of 5ht4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors
|
|
DK0914097T3
(da)
|
1996-03-12 |
2002-04-29 |
Alza Corp |
Sammensætning og doseringsform omfattende opioid antagonist
|
|
US6136780A
(en)
|
1996-03-29 |
2000-10-24 |
The Penn State Research Foundation |
Control of cancer growth through the interaction of [Met5 ]-enkephalin and the zeta (ζ) receptor
|
|
US20040024006A1
(en)
|
1996-05-06 |
2004-02-05 |
Simon David Lew |
Opioid pharmaceutical compositions
|
|
JP3648864B2
(ja)
|
1996-08-28 |
2005-05-18 |
三菱自動車工業株式会社 |
希薄燃焼内燃機関
|
|
DE19651551C2
(de)
|
1996-12-11 |
2000-02-03 |
Klinge Co Chem Pharm Fab |
Opioidantagonisthaltige galenische Formulierung
|
|
US20010036469A1
(en)
|
1997-01-13 |
2001-11-01 |
Gooberman Lance L. |
Opiate antagonist implant and process for preparation therefor
|
|
EP0880352B1
(de)
|
1997-02-14 |
1999-11-17 |
Gödecke Aktiengesellschaft |
Stabilisierung von naloxonhydrochlorid
|
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
US6329516B1
(en)
|
1997-04-28 |
2001-12-11 |
Fmc Corporation |
Lepidopteran GABA-gated chloride channels
|
|
GB9801231D0
(en)
|
1997-06-05 |
1998-03-18 |
Merck & Co Inc |
A method of treating cancer
|
|
HU9701081D0
(en)
|
1997-06-23 |
1997-08-28 |
Gene Research Lab Inc N |
Pharmaceutical composition of antitumoral activity
|
|
US6525038B1
(en)
|
1997-06-24 |
2003-02-25 |
Werner Kreutz |
Synergistic compositions for the selective control of tumor tissue
|
|
US6353004B1
(en)
|
1997-07-14 |
2002-03-05 |
Adolor Coporation |
Peripherally acting anti-pruritic opiates
|
|
US6096764A
(en)
|
1997-08-21 |
2000-08-01 |
Eli Lilly And Company |
Methods for inhibiting detrimental side-effects due to GnRH of GnRH agonist administration
|
|
US6099853A
(en)
|
1997-09-04 |
2000-08-08 |
Protein Express |
Vaginal suppository vaccine for urogenital infections
|
|
US6274591B1
(en)
|
1997-11-03 |
2001-08-14 |
Joseph F. Foss |
Use of methylnaltrexone and related compounds
|
|
US6559158B1
(en)
|
1997-11-03 |
2003-05-06 |
Ur Labs, Inc. |
Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
|
|
US5972954A
(en)
|
1997-11-03 |
1999-10-26 |
Arch Development Corporation |
Use of methylnaltrexone and related compounds
|
|
US20030158220A1
(en)
|
1997-11-03 |
2003-08-21 |
Foss Joseph F. |
Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
|
|
AU2003204844B2
(en)
|
1997-11-03 |
2007-06-07 |
Arch Development Corporation |
Use of methylnaltrexone and related compounds
|
|
EP0913152B1
(de)
|
1997-11-03 |
2001-12-19 |
Stada Arzneimittel Ag |
Stabilisiertes Kombinationsarzneimittel enthaltend Naloxone und ein Opiatanalgetikum
|
|
US6777534B1
(en)
|
1997-12-09 |
2004-08-17 |
Children's Medical Center Corporation |
Peptide antagonists of vascular endothelial growth factor
|
|
AU773642C
(en)
|
1997-12-22 |
2006-04-06 |
Mundipharma Pty Limited |
Opioid agonist/antagonist combinations
|
|
EP0930334A1
(en)
|
1998-01-16 |
1999-07-21 |
Quest International B.V. |
Polysaccharide conjugate capable of binding cellulose
|
|
AU3596599A
(en)
|
1998-01-26 |
1999-08-09 |
Unilever Plc |
Method for producing antibody fragments
|
|
GB9802251D0
(en)
|
1998-02-03 |
1998-04-01 |
Ciba Geigy Ag |
Organic compounds
|
|
CA2326761C
(en)
|
1998-04-03 |
2008-02-19 |
Ajinomoto Co., Inc. |
Antitumor agent
|
|
DE19818802A1
(de)
|
1998-04-27 |
1999-10-28 |
Dresden Arzneimittel |
Stabile Mitoxantron-Lösungen
|
|
US6359111B1
(en)
|
1998-05-28 |
2002-03-19 |
Neorx Corporation |
Opioid receptor targeting
|
|
HN1999000149A
(es)
|
1998-09-09 |
2000-01-12 |
Pfizer Prod Inc |
Derivados de 4,4-biarilpiperidina
|
|
US20010010919A1
(en)
|
1998-10-13 |
2001-08-02 |
David K. Grandy |
Opioid antagonists and methods of their use
|
|
AU3041100A
(en)
|
1999-01-05 |
2000-07-24 |
Unilever Plc |
Binding of antibody fragments to solid supports
|
|
ATE276359T1
(de)
|
1999-01-19 |
2004-10-15 |
Unilever Nv |
Verfahren zur herstellung von antikörperfragmenten
|
|
CA2293008A1
(en)
|
1999-01-28 |
2000-07-28 |
Hong Qi |
Premixed alatrofloxacin injectable compositions
|
|
WO2000046383A2
(en)
|
1999-02-05 |
2000-08-10 |
Rijksuniversiteit Leiden |
Method of modulating metabolite biosynthesis in recombinant cells
|
|
US6194382B1
(en)
|
1999-03-03 |
2001-02-27 |
Albert Einstein College Of Medicine Of Yeshiva University |
Method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists
|
|
JP4049477B2
(ja)
|
1999-03-23 |
2008-02-20 |
大鵬薬品工業株式会社 |
副作用軽減剤
|
|
CN1252264C
(zh)
|
1999-04-22 |
2006-04-19 |
荷兰联合利华有限公司 |
利用单价抗原－结合蛋白抑制病毒感染
|
|
US7129265B2
(en)
|
1999-04-23 |
2006-10-31 |
Mason R Preston |
Synergistic effects of amlodipine and atorvastatin metabolite as a basis for combination therapy
|
|
US6171620B1
(en)
|
1999-04-27 |
2001-01-09 |
Health Research, Inc. |
Method of enhancing the efficacy of anti-tumor agents
|
|
WO2000066125A1
(en)
|
1999-04-29 |
2000-11-09 |
Aventis Pharma S.A. |
Method for treating cancer using camptothecin derivatives and 5-fluorouracil
|
|
US6833349B2
(en)
|
1999-06-08 |
2004-12-21 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating inflammatory skin diseases
|
|
US20020068712A1
(en)
|
1999-07-23 |
2002-06-06 |
Troy Stevens |
Use of decreasing levels of functional transient receptor potential gene product
|
|
US20030105121A1
(en)
|
1999-07-27 |
2003-06-05 |
Bernard Bihari |
Method of preventing lipodystrophy syndrome or reversing a pre-existing syndrome in HIV-infected patients being treated with antiretroviral agents
|
|
EP1198572A2
(en)
|
1999-08-02 |
2002-04-24 |
Keygene N.V. |
Method for generating cgmmv resistant plants, genetic constructs, and obtained cgmmv-resistant plants
|
|
CA2380524A1
(en)
|
1999-08-25 |
2001-03-01 |
Barrett R. Cooper |
Compositions and methods for treating opiate intolerance
|
|
ES2226886T3
(es)
|
1999-08-31 |
2005-04-01 |
Grunenthal Gmbh |
Forma de administracion de accion retardada que contiene sacarinato de tramadol.
|
|
EP1216044A1
(en)
*
|
1999-09-29 |
2002-06-26 |
The Procter & Gamble Company |
Compositions having improved stability
|
|
US6451806B2
(en)
|
1999-09-29 |
2002-09-17 |
Adolor Corporation |
Methods and compositions involving opioids and antagonists thereof
|
|
CZ299726B6
(cs)
|
1999-11-01 |
2008-11-05 |
|
Lécivo pro lécení zácpy a syndromu dráždivého tracníku
|
|
EP1097720B1
(en)
|
1999-11-04 |
2005-10-12 |
Institut Gustave Roussy |
Antiviral agent in combination with radiation therapy for use in treatment of cancer
|
|
CA2393141C
(en)
|
1999-11-29 |
2013-08-13 |
Adolor Corporation |
Novel methods for the treatment and prevention of ileus
|
|
US6469030B2
(en)
|
1999-11-29 |
2002-10-22 |
Adolor Corporation |
Methods for the treatment and prevention of ileus
|
|
AU4136901A
(en)
|
1999-11-29 |
2001-06-18 |
Adolor Corporation |
Novel methods for the treatment and prevention of dizziness and pruritus
|
|
NZ518562A
(en)
|
1999-11-29 |
2005-04-29 |
Adolor Corp |
Novel methods and compositions involving opioids and antagonists thereof
|
|
US6384044B1
(en)
|
1999-11-29 |
2002-05-07 |
Bernard Bihari |
Method of treating cancer of the prostate
|
|
US6911455B2
(en)
|
1999-12-22 |
2005-06-28 |
Smithkline Beecham Corporation |
Methods for preparing pharmaceutical formulations
|
|
US6545010B2
(en)
|
2000-03-17 |
2003-04-08 |
Aventis Pharma S.A. |
Composition comprising camptothecin or a camptothecin derivative and a platin derivative for the treatment of cancer
|
|
US20010046968A1
(en)
|
2000-03-23 |
2001-11-29 |
Zagon Ian S. |
Opioid growth factor modulates angiogenesis
|
|
US6967075B2
(en)
|
2000-04-07 |
2005-11-22 |
Schering Corporation |
HCV replicase complexes
|
|
EP1284736A2
(en)
|
2000-05-05 |
2003-02-26 |
Pain Therapeutics, Inc. |
Opioid antagonist compositions and dosage forms
|
|
ATE440618T1
(de)
|
2000-06-22 |
2009-09-15 |
Univ Iowa Res Found |
Kombination von cpg und antikírpern gegen cd19, cd20,cd22 oder cd40 zur prävention oder behandlung von krebs.
|
|
EP1175905A1
(en)
|
2000-07-24 |
2002-01-30 |
Societe Des Produits Nestle S.A. |
Nutritional Composition
|
|
FI116089B
(sv)
|
2000-07-27 |
2005-09-15 |
Johan Tore Karlstroem |
Anordning och förfaranden vid reglar
|
|
AU2001289699B2
(en)
|
2000-07-28 |
2006-06-01 |
Cheplapharm Arzneimittel Gmbh |
New pharmaceutical composition
|
|
NZ507152A
(en)
|
2000-09-27 |
2001-06-29 |
Hiltive Pty Ltd |
Wall cladding assembly with cladding having recesses along opposite sides to engage with flanges of support members
|
|
AU2002249885A1
(en)
|
2000-11-17 |
2002-08-12 |
Adolor Corporation |
Delta agonist analgesics
|
|
DK1229130T3
(en)
|
2000-12-04 |
2014-02-24 |
Primagen B V |
TEST BASED ON nucleic acids OF ENDOSYMBIONTISKE, cellular organelles
|
|
UA73619C2
(en)
|
2000-12-13 |
2005-08-15 |
Pfizer Prod Inc |
Stable pharmaceutical compositions of nmda receptor agonist (variants) and method of treatment
|
|
EP1390061A2
(en)
|
2000-12-13 |
2004-02-25 |
Eli Lilly And Company |
Chronic treatment regimen using glucagon-like insulinotropic peptides
|
|
KR100405161B1
(ko)
|
2000-12-14 |
2003-11-12 |
신풍제약주식회사 |
록소프로펜 함유 근육주사제 조성물
|
|
GB0100115D0
(en)
|
2001-01-04 |
2001-02-14 |
Alchemia Pty Ltd |
Delivery systems
|
|
US6693125B2
(en)
|
2001-01-24 |
2004-02-17 |
Combinatorx Incorporated |
Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders
|
|
KR20040018341A
(ko)
|
2001-03-23 |
2004-03-03 |
샤이어 바이오켐 인코포레이티드 |
암치료용 약제 조성물
|
|
US20040242523A1
(en)
|
2003-03-06 |
2004-12-02 |
Ana-Farber Cancer Institue And The Univiersity Of Chicago |
Chemo-inducible cancer gene therapy
|
|
WO2002080987A1
(en)
|
2001-04-09 |
2002-10-17 |
Progenics Pharmaceuticals, Inc. |
Anti-cd19 immunotoxins
|
|
MXPA03009727A
(es)
|
2001-04-26 |
2004-01-29 |
Control Delivery Sys Inc |
SISTEMA DE SUMINISTRO DE FaRMACOS DE LIBERACIoN PROLONGADA QUE CONTIENE COFARMACOS.
|
|
EP1404323B1
(en)
|
2001-06-05 |
2009-10-28 |
The University of Chicago |
Use of methylnaltrexone to treat immune suppression
|
|
US20030108565A1
(en)
|
2001-07-10 |
2003-06-12 |
Johnson Mark E. |
Compositions and methods for delivery of proteins and adjuvants encapsulated in microspheres
|
|
EP1432429A4
(en)
|
2001-08-31 |
2005-09-21 |
Univ Louisiana State |
ANGIOGENIC INHIBITION AND DESTRUCTION OF ANGIOGENIC VACUUM WITH EXTRACTS OF NONI JUICE (MORINDA CITRIFOLIA)
|
|
US7056500B2
(en)
|
2001-10-18 |
2006-06-06 |
Nektar Therapeutics Al, Corporation |
Polymer conjugates of opioid antagonists
|
|
US20030144312A1
(en)
|
2001-10-30 |
2003-07-31 |
Schoenhard Grant L. |
Inhibitors of ABC drug transporters in multidrug resistant cancer cells
|
|
WO2003037365A1
(en)
|
2001-11-01 |
2003-05-08 |
The Johns Hopkins University |
Methods and compositions for treating vascular leak using hepatocyte growth factor
|
|
JP2005511693A
(ja)
|
2001-11-29 |
2005-04-28 |
シェーリング コーポレイション |
回転異性体の薬学的に活性な塩の量が増加した組成物の調製のためのプロセス
|
|
JP4357965B2
(ja)
|
2001-12-21 |
2009-11-04 |
メルク エンド カムパニー インコーポレーテッド |
メタボトロピックグルタミン酸受容体−５のヘテロアリール置換ピロールモジュレーター
|
|
US20050011468A1
(en)
|
2002-02-04 |
2005-01-20 |
Jonathan Moss |
Use of methylnaltrexone in treating gastrointestinal dysfunction in equines
|
|
US20040259898A1
(en)
|
2002-02-04 |
2004-12-23 |
Jonathan Moss |
Use of methylnaltrexone in treating gastrointestinal dysfunction in equines
|
|
US7074825B2
(en)
|
2002-03-07 |
2006-07-11 |
Huanbiao Mo |
Composition and method for treating cancer
|
|
AU2003220290B2
(en)
|
2002-03-14 |
2007-06-14 |
Euro-Celtique S.A. |
Naltrexone hydrochloride compositions
|
|
US20050176685A1
(en)
|
2002-04-05 |
2005-08-11 |
Daifotis Anastasia G. |
Method for inhibiting bone resorption with an alendronate and vitamin d formulation
|
|
US20030191147A1
(en)
|
2002-04-09 |
2003-10-09 |
Barry Sherman |
Opioid antagonist compositions and dosage forms
|
|
US7355081B2
(en)
|
2002-04-17 |
2008-04-08 |
The University Of North Carolina At Chapel Hill |
Curcumin analogues and uses thereof
|
|
EP1515754B1
(en)
|
2002-05-17 |
2011-05-25 |
Board Of Regents, The University Of Texas System |
Beta-2-glycoprotein 1 is an inhibitor of angiogenesis
|
|
US7012100B1
(en)
|
2002-06-04 |
2006-03-14 |
Avolix Pharmaceuticals, Inc. |
Cell migration inhibiting compositions and methods and compositions for treating cancer
|
|
US6986901B2
(en)
|
2002-07-15 |
2006-01-17 |
Warner-Lambert Company Llc |
Gastrointestinal compositions
|
|
US20040010997A1
(en)
|
2002-07-17 |
2004-01-22 |
Oren Close |
Guides to align masonry walls defining apertures, and methods of use
|
|
US7160913B2
(en)
|
2002-09-13 |
2007-01-09 |
Thomas Jefferson University |
Methods and kit for treating Parkinson's disease
|
|
US7691374B2
(en)
|
2002-10-23 |
2010-04-06 |
Health Research, Inc. |
Method for increasing the efficacy of anti-tumor agents by anti-endoglin antibody
|
|
ATE444295T1
(de)
|
2002-11-08 |
2009-10-15 |
Mallinckrodt Inc |
Verfahren zur herstellung von quaternäre n-alkyl morphinan alkaloid salzen
|
|
JP2004183371A
(ja)
|
2002-12-04 |
2004-07-02 |
Inax Corp |
ユニットバスの補強構造
|
|
WO2004054511A2
(en)
|
2002-12-13 |
2004-07-01 |
The Regents Of The University Of California |
Analgesic combination comprising nalbuphine
|
|
WO2004054569A1
(en)
|
2002-12-16 |
2004-07-01 |
Council Of Scientific And Industrial Research |
Pharmaceutical composition containing brevifoliol for use in chemotherapeutic treatment of human beings
|
|
DE602004016127D1
(de)
|
2003-03-07 |
2008-10-09 |
Lilly Co Eli |
Antagonisten der opioidrezeptoren
|
|
BRPI0409128A
(pt)
*
|
2003-04-08 |
2006-03-28 |
Progenics Pharm Inc |
uso de antagonistas de opióides periféricos, especialmente metilnaltrexona para tratar sìndrome de intestino irritável
|
|
SI2368553T1
(sl)
|
2003-04-08 |
2015-05-29 |
Progenics Pharmaceuticals, Inc. |
Farmacevtske formulacije, vsebujoče metilnatrekson
|
|
AU2004229464A1
(en)
|
2003-04-08 |
2004-10-28 |
Progenics Pharmaceuticals, Inc. |
Combination therapy for constipation comprising a laxative and a peripheral opioid antagonist
|
|
PT2316456T
(pt)
|
2003-04-29 |
2017-09-05 |
Orexigen Therapeutics Inc |
Composições para afetar a perda de peso compreendendo naltrexona e bupropion
|
|
US6992193B2
(en)
|
2003-06-10 |
2006-01-31 |
Adolor Corporation |
Sulfonylamino phenylacetamide derivatives and methods of their use
|
|
WO2005016244A2
(en)
|
2003-06-13 |
2005-02-24 |
Microbia, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
US7494979B2
(en)
|
2003-06-13 |
2009-02-24 |
Ironwood Pharmaceuticals, Inc. |
Method for treating congestive heart failure and other disorders
|
|
AU2003903387A0
(en)
|
2003-07-02 |
2003-07-17 |
Sirtex Medical Limited |
Combination therapy for treatment of neoplasia
|
|
EP1682006A4
(en)
|
2003-10-29 |
2011-01-26 |
Physiosonics Inc |
METHOD AND DEVICE FOR DETERMINING A MIDDLE LINE OF AN ULTRASONIC LIQUID FLOW
|
|
SE0303135D0
(sv)
|
2003-11-25 |
2003-11-25 |
Lipocore Holding Ab |
Controlled food effect composition
|
|
US6984403B2
(en)
|
2003-12-04 |
2006-01-10 |
Pfizer Inc. |
Azithromycin dosage forms with reduced side effects
|
|
US8946262B2
(en)
|
2003-12-04 |
2015-02-03 |
Adolor Corporation |
Methods of preventing and treating gastrointestinal dysfunction
|
|
AU2004303425C1
(en)
|
2003-12-19 |
2010-02-18 |
Schering Corporation |
Pharmaceutical compositions
|
|
BRPI0418294A
(pt)
|
2003-12-31 |
2007-05-02 |
Pfizer Prod Inc |
composições sólidas farmacêuticas estabilizadas de medicamentos de baixa solubilidade, poloxámeros e polìmeros estabilizantes
|
|
JP2005213763A
(ja)
|
2004-01-27 |
2005-08-11 |
Yasushi Namihana |
ドア開閉補助装置
|
|
US20070082044A1
(en)
|
2004-03-10 |
2007-04-12 |
Trustees Of Tufts College |
Synergistic effect of compositions comprising carotenoids selected from lutein, beta-carotene and lycopene
|
|
TW200533339A
(en)
|
2004-03-16 |
2005-10-16 |
Bristol Myers Squibb Co |
Therapeutic synergy of anti-cancer compounds
|
|
US6946556B1
(en)
|
2004-05-21 |
2005-09-20 |
Acura Pharmaceuticals, Inc. |
Preparation of opioid analgesics by a one-pot process
|
|
US7094775B2
(en)
|
2004-06-30 |
2006-08-22 |
Bone Care International, Llc |
Method of treating breast cancer using a combination of vitamin D analogues and other agents
|
|
US7388008B2
(en)
|
2004-08-02 |
2008-06-17 |
Ambrilia Biopharma Inc. |
Lysine based compounds
|
|
US20060063792A1
(en)
|
2004-09-17 |
2006-03-23 |
Adolor Corporation |
Substituted morphinans and methods of their use
|
|
WO2006034455A2
(en)
|
2004-09-23 |
2006-03-30 |
Vasgene Therapeutics, Inc. |
Polipeptide compounds for inhibiting angiogenesis and tumor growth
|
|
JP5238255B2
(ja)
|
2004-09-30 |
2013-07-17 |
ベクトン・ディキンソン・アンド・カンパニー |
ガラス製容器内の残留物を削減又は除去するための方法及びそれにしたがって製造されたガラス製容器
|
|
US20060177380A1
(en)
|
2004-11-24 |
2006-08-10 |
Acura Pharmaceuticals, Inc. |
Methods and compositions for deterring abuse of orally administered pharmaceutical products
|
|
EP1845989A1
(en)
|
2005-01-20 |
2007-10-24 |
Progenics Pharmaceuticals, Inc. |
Use of methylnaltrexone and related compounds to treat post-operative gastrointestinal dysfunction
|
|
US8524731B2
(en)
|
2005-03-07 |
2013-09-03 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
|
CN101171010B
(zh)
|
2005-03-07 |
2014-09-17 |
芝加哥大学 |
阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途
|
|
AR057325A1
(es)
|
2005-05-25 |
2007-11-28 |
Progenics Pharm Inc |
Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
|
|
AR057035A1
(es)
|
2005-05-25 |
2007-11-14 |
Progenics Pharm Inc |
SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
|
|
AU2006255274A1
(en)
|
2005-06-03 |
2006-12-14 |
The University Of Chicago |
Modulation of microbial pathogen-host cell interactions
|
|
CA2609985A1
(en)
|
2005-06-03 |
2007-05-10 |
The University Of Chicago |
Modulation of cell barrier dysfunction
|
|
US20080194611A1
(en)
|
2005-06-03 |
2008-08-14 |
Alverdy John C |
Modulation of Cell Barrier Dysfunction
|
|
AU2006258060A1
(en)
|
2005-06-09 |
2006-12-21 |
Mallinckrodt Inc. |
Method for separation and purification of naltrexone by preparative chromatography
|
|
PE20070207A1
(es)
|
2005-07-22 |
2007-03-09 |
Genentech Inc |
Tratamiento combinado de los tumores que expresan el her
|
|
JP2009506080A
(ja)
|
2005-08-30 |
2009-02-12 |
クィーンズ ユニバーシティー アット キングストン |
超低用量のα−２−受容体アンタゴニストを用いる、オピオイド受容体アゴニストの治療作用の増強方法および／またはオピオイド受容体アゴニストに対する耐性の阻害方法もしくは逆転方法
|
|
PL116330U1
(en)
|
2005-10-31 |
2007-04-02 |
Alza Corp |
Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
|
|
US20070259939A1
(en)
|
2006-05-04 |
2007-11-08 |
Accelerated Technologies |
Using naltrexone as a multi-purpose health supplement to improve the human condition and preventing multiple diseases and infirmities by stimulating immune system vitality and robustness
|
|
CA2671200A1
(en)
|
2006-07-21 |
2008-01-24 |
Lab International Srl |
Hydrophilic abuse deterrent delivery system
|
|
TW200815451A
(en)
|
2006-08-04 |
2008-04-01 |
Wyeth Corp |
6-carboxy-normorphinan derivatives, synthesis and uses thereof
|
|
TWI489984B
(zh)
|
2006-08-04 |
2015-07-01 |
Wyeth Corp |
用於非經腸道傳輸化合物之配方及其用途
|
|
WO2008021394A2
(en)
|
2006-08-15 |
2008-02-21 |
Theraquest Biosciences, Llc |
Pharmaceutical formulations of cannabinoids and method of use
|
|
TW200817048A
(en)
|
2006-09-08 |
2008-04-16 |
Wyeth Corp |
Dry powder compound formulations and uses thereof
|
|
CA2670136A1
(en)
|
2006-11-22 |
2008-05-29 |
Progenics Pharmaceuticals, Inc. |
7,8-saturated-4,5-epoxy-morphinanium analogs
|
|
CA2670386A1
(en)
|
2006-11-22 |
2008-05-29 |
Progenics Pharmaceuticals, Inc. |
Processes for synthesizing quaternary 4,5-epoxy-morphinan analogs and isolating their n-stereoisomers
|
|
JP2010510326A
(ja)
|
2006-11-22 |
2010-04-02 |
プロジェニックス ファーマスーティカルス インコーポレーテッド |
４，５−エポキシ−モルフィナニウム類似体のｎ−オキシド類
|
|
TW200843802A
(en)
|
2007-02-09 |
2008-11-16 |
Drugtech Corp |
Compositions for improving gastrointestinal nutrient and drug absorption
|
|
CA2945356C
(en)
|
2007-03-29 |
2021-03-23 |
Progenics Pharmaceuticals, Inc. |
(r)-n-methylnaltrexone bromide and pharmaceutical compostitions therof useful as peripheral .mu. opioid receptor antagonist
|
|
PL2137191T3
(pl)
|
2007-03-29 |
2016-12-30 |
|
Antagoniści obwodowego receptora opioidowego i ich zastosowania
|
|
PT2565195E
(pt)
|
2007-03-29 |
2015-07-28 |
Wyeth Llc |
Antagonistas e receptor opióide periférico e respectivas utilizações
|
|
CN101959892B
(zh)
|
2008-02-06 |
2014-01-08 |
普罗热尼奇制药公司 |
(r),(r)-2,2’-二-甲基纳曲酮的制备和用途
|
|
BRPI0912219A2
(pt)
|
2008-05-07 |
2015-10-06 |
Nektar Therapeutics |
método, forma de dose unitária, e, antagonista de opióide oralmente administrável que atua perifericamente.
|
|
CA2676881C
(en)
|
2008-09-30 |
2017-04-25 |
Wyeth |
Peripheral opioid receptor antagonists and uses thereof
|
|
CN101845047B
(zh)
|
2009-12-31 |
2011-12-07 |
南京臣功制药有限公司 |
一种溴甲基纳曲酮的制备方法
|
|
US8524276B2
(en)
|
2010-03-11 |
2013-09-03 |
Wyeth, Llc |
Oral formulations and lipophilic salts of methylnaltrexone
|
|
CN110384701A
(zh)
|
2011-12-19 |
2019-10-29 |
萨利克斯药品有限公司 |
使用甲基纳曲酮口服组合物治疗和预防阿片类诱发型便秘的方法
|
|
US10485798B2
(en)
|
2012-08-22 |
2019-11-26 |
Aptapharma Inc. |
Methylnaltrexone nasal formulations, methods of making, and use thereof
|
|
BR112021022194A2
(pt)
|
2019-05-07 |
2021-12-28 |
Bausch Health Ireland Ltd |
Formulações líquidas para dosagem oral de metilnaltrexona
|