JP2007502861A5 - - Google Patents

Download PDF

Info

Publication number
JP2007502861A5
JP2007502861A5 JP2006532538A JP2006532538A JP2007502861A5 JP 2007502861 A5 JP2007502861 A5 JP 2007502861A5 JP 2006532538 A JP2006532538 A JP 2006532538A JP 2006532538 A JP2006532538 A JP 2006532538A JP 2007502861 A5 JP2007502861 A5 JP 2007502861A5
Authority
JP
Japan
Prior art keywords
trna synthetase
composition
pharmaceutically acceptable
synthetase inhibitor
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006532538A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007502861A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/013614 external-priority patent/WO2005009336A2/en
Publication of JP2007502861A publication Critical patent/JP2007502861A/ja
Publication of JP2007502861A5 publication Critical patent/JP2007502861A5/ja
Pending legal-status Critical Current

Links

JP2006532538A 2003-05-01 2004-05-03 抗菌方法及び組成物 Pending JP2007502861A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46737703P 2003-05-01 2003-05-01
US48648203P 2003-07-10 2003-07-10
PCT/US2004/013614 WO2005009336A2 (en) 2003-05-01 2004-05-03 Antibacterial methods and compositions

Publications (2)

Publication Number Publication Date
JP2007502861A JP2007502861A (ja) 2007-02-15
JP2007502861A5 true JP2007502861A5 (enExample) 2007-06-21

Family

ID=34107519

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006532538A Pending JP2007502861A (ja) 2003-05-01 2004-05-03 抗菌方法及び組成物

Country Status (6)

Country Link
US (1) US20040224981A1 (enExample)
EP (1) EP1619947A4 (enExample)
JP (1) JP2007502861A (enExample)
AU (1) AU2004258821A1 (enExample)
CA (1) CA2523651A1 (enExample)
WO (1) WO2005009336A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004218481A1 (en) * 2003-03-03 2004-09-16 Replidyne Inc Substituted thiophenes with antibacterial activity
AU2006226750B2 (en) 2005-03-23 2012-07-19 Oculus Innovative Sciences, Inc. Method of treating skin ulcers using oxidative reductive potential water solution
CA2606804A1 (en) * 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Antimicrobial agents
WO2007085018A2 (en) 2006-01-20 2007-07-26 Oculus Innovative Sciences, Inc. Methods of treating or preventing inflammation and hypersensitivity with oxidative reductive potential water solution
AU2007300290B2 (en) * 2006-09-26 2012-11-15 Crestone, Inc. Enantiomeric compounds with antibacterial activity
ES2392897T3 (es) * 2006-09-26 2012-12-14 Crestone, Inc. Compuestos tienopiridona sustituidos con actividad antibacteriana
WO2010099477A2 (en) 2009-02-27 2010-09-02 Atyr Pharma, Inc. Polypeptide structural motifs associated with cell signaling activity
CN102480972B (zh) 2009-06-15 2014-12-10 奥古露丝创新科学公司 含有次氯酸的溶液及其使用方法
JP6066900B2 (ja) 2010-04-26 2017-01-25 エータイアー ファーマ, インコーポレイテッド システイニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
US8961960B2 (en) 2010-04-27 2015-02-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases
ES2638311T3 (es) 2010-04-27 2017-10-19 Atyr Pharma, Inc. Descubrimiento innovador de composiciones terapéuticas, diagnósticas y de anticuerpos relacionadas con fragmentos de proteína de treonil ARNt sintetasas
JP6008837B2 (ja) 2010-04-28 2016-10-19 エータイアー ファーマ, インコーポレイテッド アラニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
US8986680B2 (en) 2010-04-29 2015-03-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases
WO2011139907A2 (en) 2010-04-29 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
CA2797799C (en) 2010-05-03 2020-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-trna synthetases
JP6008841B2 (ja) 2010-05-03 2016-10-19 エータイアー ファーマ, インコーポレイテッド メチオニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
AU2011248227B2 (en) 2010-05-03 2016-12-01 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases
US8961961B2 (en) 2010-05-03 2015-02-24 a Tyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of arginyl-tRNA synthetases
EP2566499B1 (en) 2010-05-04 2017-01-25 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex
JP6008843B2 (ja) 2010-05-04 2016-10-19 エータイアー ファーマ, インコーポレイテッド グルタミル−プロリルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
EP2568996B1 (en) 2010-05-14 2017-10-04 aTyr Pharma, Inc. Therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
AU2011256366C1 (en) 2010-05-17 2017-06-15 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases
CN103096913B (zh) 2010-05-27 2017-07-18 Atyr 医药公司 与谷氨酰胺酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CA2800281C (en) 2010-06-01 2021-01-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases
CA2804416C (en) 2010-07-12 2020-04-28 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases
US8999321B2 (en) 2010-07-12 2015-04-07 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
CA2804278C (en) 2010-07-12 2021-07-13 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases
KR20130102534A (ko) 2010-07-12 2013-09-17 에이티와이알 파마, 인코포레이티드 히스티딜­trna 합성효소의 단백질 단편에 관련된 치료적, 진단적, 및 항체 조성물의 혁신적 발견
WO2012014109A1 (en) 2010-07-30 2012-02-02 Ranbaxy Laboratories Limited Heterocyclic sulfonamides as inhibitors of transfer rna synthetase for use as antibacterial agents
JP5964304B2 (ja) 2010-08-25 2016-08-03 エータイアー ファーマ, インコーポレイテッド チロシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
EP2624857B1 (en) 2010-10-06 2017-08-02 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tryptophanyl trna synthetases
JP2013538868A (ja) * 2010-10-08 2013-10-17 ヘルパービー セラピューティクス リミテッド 新規な組成物
WO2012054738A1 (en) * 2010-10-22 2012-04-26 Brown University Combination of an aminoacyl - trna synthetase inhibitor with a further antibacterial agent for attenuating multiple drug resistance
US9714419B2 (en) 2011-08-09 2017-07-25 Atyr Pharma, Inc. PEGylated tyrosyl-tRNA synthetase polypeptides
US9816084B2 (en) 2011-12-06 2017-11-14 Atyr Pharma, Inc. Aspartyl-tRNA synthetases
WO2013086228A1 (en) 2011-12-06 2013-06-13 Atyr Pharma, Inc. Pegylated aspartyl-trna synthetase polypeptides
CA2858613A1 (en) 2011-12-29 2013-08-08 Atyr Pharma, Inc. Aspartyl-trna synthetase-fc conjugates
CA2869717C (en) 2012-04-13 2022-09-06 Becton, Dickinson And Company Reflex testing of samples using residual materials from a prior test
ES2708565T3 (es) 2013-03-15 2019-04-10 Atyr Pharma Inc Conjugados de Fc-histidil-ARNt sintetasa
US10913736B2 (en) 2014-08-22 2021-02-09 University Of Washington Specific inhibitors of methionyl-tRNA synthetase
JP2019196307A (ja) 2016-09-15 2019-11-14 武田薬品工業株式会社 複素環アミド化合物
EP3612215B1 (en) 2017-04-20 2024-08-28 aTyr Pharma, Inc. Compositions for treating lung inflammation
US11261201B2 (en) 2018-01-12 2022-03-01 President And Fellows Of Harvard College TRNA synthetase inhibitors
TW202214611A (zh) * 2020-08-25 2022-04-16 大陸商杭州中美華東製藥有限公司 莫匹羅星的提取方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1196284A (en) * 1982-05-28 1985-11-05 Joshua Oduro-Yeboah Pharmaceutical formulations
GB8415579D0 (en) * 1984-06-19 1984-07-25 Beecham Group Plc Compounds
IE59628B1 (en) * 1986-06-26 1994-03-09 Beecham Group Plc Treatment of fungal infections
AU692486B2 (en) * 1993-10-22 1998-06-11 Smithkline Beecham Corporation Pharmaceutical or veterinary composition comprising mupirocin or a salt thereof in a cream base
GB9424562D0 (en) * 1994-12-06 1995-01-25 Giltech Ltd Product
GB9507825D0 (en) * 1995-04-18 1995-05-31 Wet Pieter M De Method of treatment
US5726195A (en) * 1995-07-28 1998-03-10 Cubist Pharmaceuticals, Inc. Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents
US6169102B1 (en) * 1996-06-25 2001-01-02 Takeda Chemical Industries, Ltd. Oxazolone derivatives and their use as anti-Helicobacter pylori agent
US6448059B1 (en) * 1996-09-13 2002-09-10 Thomas Jefferson University Methods and composition for inhibition of tRNA activities
US5824657A (en) * 1997-03-18 1998-10-20 Cubist Pharmaceuticals, Inc. Aminoacyl sulfamides for the treatment of hyperproliferative disorders
US5939458A (en) * 1997-09-22 1999-08-17 Henry; James P. Reduction of hair growth
JP2002513005A (ja) * 1998-04-29 2002-05-08 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー Mrs阻害剤および殺菌剤用のキノロン類
AU5822099A (en) * 1998-09-18 2000-04-10 Cubist Pharmaceuticals, Inc. Tetracyclic heterocycles as antimicrobial agents
GB9822241D0 (en) * 1998-10-12 1998-12-09 Smithkline Beecham Plc Novel compounds
AU769652B2 (en) * 1999-05-05 2004-01-29 Cubist Pharmaceuticals, Inc. Novel prolines as antimicrobial agents
AU776773B2 (en) * 1999-05-05 2004-09-23 Cubist Pharmaceuticals, Inc. Novel catechols as antimicrobial agents
JP2003500397A (ja) * 1999-05-19 2003-01-07 スミスクライン ビーチャム パブリック リミテッド カンパニー Mrs阻害剤としての2−nh−ピリドンおよびピリミドン
GB9911594D0 (en) * 1999-05-19 1999-07-21 Smithkline Beecham Plc Novel compounds
IL137363A (en) * 2000-07-18 2005-12-18 Agis Ind 1983 Ltd Pharmaceutical compositions containing mupirocin
GB0228545D0 (en) * 2002-12-06 2003-01-15 Glaxo Group Ltd Novel compounds
GB0302546D0 (en) * 2003-02-04 2003-03-12 Glaxo Group Ltd Novel compounds
AU2004218481A1 (en) * 2003-03-03 2004-09-16 Replidyne Inc Substituted thiophenes with antibacterial activity
DE10318991A1 (de) * 2003-04-25 2004-11-18 Heraeus Kulzer Gmbh & Co. Kg Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung

Similar Documents

Publication Publication Date Title
JP2007502861A5 (enExample)
JP2021063088A5 (enExample)
CN1878757A (zh) 吡啶酮衍生物及其应用
AR055363A1 (es) Formulaciones farmaceuticas que comprenden un beta 2- agonista de accion prolongada para administracion por nebulizacion
EA201101672A1 (ru) Замещенные производные аминомасляной кислоты в качестве ингибиторов неприлизина
HRP20120494T1 (hr) Derivati purina za uporabu kao agonista adenozin a2a receptora
JP2009545603A5 (enExample)
RU2009126767A (ru) Производное 1-фенил-1-тио-d-глюцитола
HRP20211762T1 (hr) Derivati benzoksaborola za liječenje bakterijskih infekcija
AR050838A1 (es) Formulacion farmaceutica. para el tratamiento de una infeccion optica
JP2009544665A5 (enExample)
RU2011138962A (ru) Производные 4-изопропилфенилглюцита в качестве ингибиторов sglt1
EP1816122A3 (en) 3,4,5-substituted piperidines as therapeutic compounds
JP2005508368A5 (enExample)
RU2002100058A (ru) Кристаллические производные 1-метилкарбапенема
DE502004006500D1 (de) Pharmazeutische formulierung des telmisartan natriumsalzes
AR038618A1 (es) Forma poliformica cristalina de clorhidratos de irinotecan
JP2004532828A5 (enExample)
EP1885380A4 (en) PHARMACEUTICAL COMPOSITIONS CONTAINING ARSENE (III ACID), SODIUM SALT AND THEIR DERIVATIVES FOR THE TREATMENT OF UROGENITAL CANCER AND METASTASES THEREOF
FR2906140B1 (fr) Forme galenique pour l'administration par voie trans-muqueuse de principes actifs
RU2005128132A (ru) Лечение бактериальных заболеваний органов дыхания путем местного применения фторхинолонов
BR9807330A (pt) Agentes inibidores do progresso de pterìgio e recorrência pós-operatória do mesmo
JP2005511708A5 (enExample)
EP1867329A3 (en) 5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamides as therapeutic compounds
JP2007153892A5 (enExample)