CA2523651A1 - Antibacterial methods and compositions - Google Patents
Antibacterial methods and compositions Download PDFInfo
- Publication number
- CA2523651A1 CA2523651A1 CA002523651A CA2523651A CA2523651A1 CA 2523651 A1 CA2523651 A1 CA 2523651A1 CA 002523651 A CA002523651 A CA 002523651A CA 2523651 A CA2523651 A CA 2523651A CA 2523651 A1 CA2523651 A1 CA 2523651A1
- Authority
- CA
- Canada
- Prior art keywords
- aureus
- mupirocin
- composition
- trna synthetase
- mrsi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46737703P | 2003-05-01 | 2003-05-01 | |
| US60/467,377 | 2003-05-01 | ||
| US48648203P | 2003-07-10 | 2003-07-10 | |
| US60/486,482 | 2003-07-10 | ||
| PCT/US2004/013614 WO2005009336A2 (en) | 2003-05-01 | 2004-05-03 | Antibacterial methods and compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2523651A1 true CA2523651A1 (en) | 2005-02-03 |
Family
ID=34107519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002523651A Abandoned CA2523651A1 (en) | 2003-05-01 | 2004-05-03 | Antibacterial methods and compositions |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040224981A1 (enExample) |
| EP (1) | EP1619947A4 (enExample) |
| JP (1) | JP2007502861A (enExample) |
| AU (1) | AU2004258821A1 (enExample) |
| CA (1) | CA2523651A1 (enExample) |
| WO (1) | WO2005009336A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004078119A2 (en) * | 2003-03-03 | 2004-09-16 | Replidyne Inc. | Substituted thiophenes with antibacterial activity |
| WO2006102680A2 (en) | 2005-03-23 | 2006-09-28 | Oculus Innovative Sciences, Inc. | Method of treating second and third degree burns using oxidative reductive potential water solution |
| WO2006117762A2 (en) | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Antimicrobial agents |
| BRPI0706677A2 (pt) | 2006-01-20 | 2011-04-05 | Oculus Innovative Sciences Inc | métodos de tratamento ou prevenção de sinusite com solução aquosa com potencial de oxirredução |
| WO2008039639A2 (en) * | 2006-09-26 | 2008-04-03 | Crestone, Inc. | Substituted thienopyridone compounds with antibacterial activity |
| CN101652140B (zh) * | 2006-09-26 | 2013-07-10 | 克莱斯通公司 | 具有抗菌活性的对映体化合物 |
| ES2552773T3 (es) | 2009-02-27 | 2015-12-02 | Atyr Pharma, Inc. | Motivos estructurales de polipéptidos asociados con la actividad de señalización celular |
| WO2010148004A1 (en) | 2009-06-15 | 2010-12-23 | Oculus Innovative Sciences, Inc. | Solution containing hypochlorous acid and methods of using same |
| CA2797093C (en) | 2010-04-26 | 2019-10-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase |
| CA2797362C (en) | 2010-04-27 | 2020-12-08 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases |
| CA2797259C (en) | 2010-04-27 | 2020-09-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl trna synthetases |
| WO2011139853A2 (en) | 2010-04-28 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases |
| US8986680B2 (en) | 2010-04-29 | 2015-03-24 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases |
| EP2563383B1 (en) | 2010-04-29 | 2017-03-01 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases |
| WO2011139986A2 (en) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases |
| CA2797977C (en) | 2010-05-03 | 2019-08-20 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases |
| AU2011248357B2 (en) | 2010-05-03 | 2017-02-23 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-tRNA synthetases |
| CN103140233B (zh) | 2010-05-03 | 2017-04-05 | Atyr 医药公司 | 与甲硫氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现 |
| EP2566499B1 (en) | 2010-05-04 | 2017-01-25 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex |
| US9062301B2 (en) | 2010-05-04 | 2015-06-23 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-tRNA synthetases |
| CA2799197C (en) | 2010-05-14 | 2019-10-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases |
| US9034598B2 (en) | 2010-05-17 | 2015-05-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases |
| AU2011258106B2 (en) | 2010-05-27 | 2017-02-23 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases |
| CN103118694B (zh) | 2010-06-01 | 2016-08-03 | Atyr医药公司 | 与赖氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现 |
| CA2804278C (en) | 2010-07-12 | 2021-07-13 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases |
| EP2593126B1 (en) | 2010-07-12 | 2017-09-20 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
| US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| JP6116479B2 (ja) | 2010-07-12 | 2017-04-19 | エータイアー ファーマ, インコーポレイテッド | グリシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| WO2012014109A1 (en) | 2010-07-30 | 2012-02-02 | Ranbaxy Laboratories Limited | Heterocyclic sulfonamides as inhibitors of transfer rna synthetase for use as antibacterial agents |
| JP5964304B2 (ja) | 2010-08-25 | 2016-08-03 | エータイアー ファーマ, インコーポレイテッド | チロシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| CA2812795C (en) | 2010-10-06 | 2021-08-31 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases |
| EP2624817A1 (en) * | 2010-10-08 | 2013-08-14 | Helperby Therapeutics Limited | Novel composition |
| WO2012054738A1 (en) * | 2010-10-22 | 2012-04-26 | Brown University | Combination of an aminoacyl - trna synthetase inhibitor with a further antibacterial agent for attenuating multiple drug resistance |
| WO2013022982A2 (en) | 2011-08-09 | 2013-02-14 | Atyr Pharma, Inc. | Pegylated tyrosyl-trna synthetase polypeptides |
| US9816084B2 (en) | 2011-12-06 | 2017-11-14 | Atyr Pharma, Inc. | Aspartyl-tRNA synthetases |
| WO2013086228A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Pegylated aspartyl-trna synthetase polypeptides |
| CN104220461A (zh) | 2011-12-29 | 2014-12-17 | Atyr医药公司 | 天冬氨酰-tRNA合成酶-FC缀合物 |
| AU2013246418B2 (en) * | 2012-04-13 | 2017-02-23 | Becton, Dickinson And Company | Reflex testing of samples using residual materials from a prior test |
| CN114717206A (zh) | 2013-03-15 | 2022-07-08 | Atyr 医药公司 | 组氨酰-trna合成酶-fc缀合物 |
| US10913736B2 (en) | 2014-08-22 | 2021-02-09 | University Of Washington | Specific inhibitors of methionyl-tRNA synthetase |
| JP2019196307A (ja) * | 2016-09-15 | 2019-11-14 | 武田薬品工業株式会社 | 複素環アミド化合物 |
| ES2994451T3 (en) | 2017-04-20 | 2025-01-24 | Atyr Pharma Inc | Compositions for treating lung inflammation |
| WO2019140265A1 (en) * | 2018-01-12 | 2019-07-18 | President And Fellows Of Harvard College | Trna synthetase inhibitors |
| TWI923608B (zh) * | 2020-08-25 | 2026-05-01 | 大陸商杭州中美華東製藥有限公司 | 莫匹羅星的提取方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1196284A (en) * | 1982-05-28 | 1985-11-05 | Joshua Oduro-Yeboah | Pharmaceutical formulations |
| GB8415579D0 (en) * | 1984-06-19 | 1984-07-25 | Beecham Group Plc | Compounds |
| IE59628B1 (en) * | 1986-06-26 | 1994-03-09 | Beecham Group Plc | Treatment of fungal infections |
| KR100374462B1 (ko) * | 1993-10-22 | 2003-06-09 | 스미스클라인 비참 코포레이션 | 신규조성물 |
| GB9424562D0 (en) * | 1994-12-06 | 1995-01-25 | Giltech Ltd | Product |
| GB9507825D0 (en) * | 1995-04-18 | 1995-05-31 | Wet Pieter M De | Method of treatment |
| US5726195A (en) * | 1995-07-28 | 1998-03-10 | Cubist Pharmaceuticals, Inc. | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents |
| US6169102B1 (en) * | 1996-06-25 | 2001-01-02 | Takeda Chemical Industries, Ltd. | Oxazolone derivatives and their use as anti-Helicobacter pylori agent |
| US6448059B1 (en) * | 1996-09-13 | 2002-09-10 | Thomas Jefferson University | Methods and composition for inhibition of tRNA activities |
| US5824657A (en) * | 1997-03-18 | 1998-10-20 | Cubist Pharmaceuticals, Inc. | Aminoacyl sulfamides for the treatment of hyperproliferative disorders |
| US5939458A (en) * | 1997-09-22 | 1999-08-17 | Henry; James P. | Reduction of hair growth |
| CN1307565A (zh) * | 1998-04-29 | 2001-08-08 | 史密丝克莱恩比彻姆有限公司 | 用作mrs抑制剂和杀菌剂的喹诺酮化合物 |
| WO2000017206A1 (en) * | 1998-09-18 | 2000-03-30 | Cubist Pharmaceuticals, Inc. | Tetracyclic heterocycles as antimicrobial agents |
| GB9822241D0 (en) * | 1998-10-12 | 1998-12-09 | Smithkline Beecham Plc | Novel compounds |
| US6348482B1 (en) * | 1999-05-05 | 2002-02-19 | Merck & Co., Inc. | Catechols as antimicrobial agents |
| EP1176959B1 (en) * | 1999-05-05 | 2006-03-08 | Merck & Co., Inc. | Novel prolines as antimicrobial agents |
| GB9911594D0 (en) * | 1999-05-19 | 1999-07-21 | Smithkline Beecham Plc | Novel compounds |
| WO2000071524A1 (en) * | 1999-05-19 | 2000-11-30 | Smithkline Beecham Plc | 2-nh-pyridones and pyrimidones as mrs inhibitors |
| IL137363A (en) * | 2000-07-18 | 2005-12-18 | Agis Ind 1983 Ltd | Pharmaceutical compositions containing mupirocin |
| GB0228545D0 (en) * | 2002-12-06 | 2003-01-15 | Glaxo Group Ltd | Novel compounds |
| GB0302546D0 (en) * | 2003-02-04 | 2003-03-12 | Glaxo Group Ltd | Novel compounds |
| WO2004078119A2 (en) * | 2003-03-03 | 2004-09-16 | Replidyne Inc. | Substituted thiophenes with antibacterial activity |
| DE10318991A1 (de) * | 2003-04-25 | 2004-11-18 | Heraeus Kulzer Gmbh & Co. Kg | Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung |
-
2004
- 2004-05-03 WO PCT/US2004/013614 patent/WO2005009336A2/en not_active Ceased
- 2004-05-03 JP JP2006532538A patent/JP2007502861A/ja active Pending
- 2004-05-03 US US10/837,881 patent/US20040224981A1/en not_active Abandoned
- 2004-05-03 AU AU2004258821A patent/AU2004258821A1/en not_active Abandoned
- 2004-05-03 CA CA002523651A patent/CA2523651A1/en not_active Abandoned
- 2004-05-03 EP EP04775930A patent/EP1619947A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1619947A2 (en) | 2006-02-01 |
| JP2007502861A (ja) | 2007-02-15 |
| WO2005009336A3 (en) | 2005-10-13 |
| WO2005009336A9 (en) | 2005-04-14 |
| AU2004258821A1 (en) | 2005-02-03 |
| WO2005009336A2 (en) | 2005-02-03 |
| US20040224981A1 (en) | 2004-11-11 |
| EP1619947A4 (en) | 2006-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |