JP2009541269A5 - - Google Patents
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- Publication number
- JP2009541269A5 JP2009541269A5 JP2009515888A JP2009515888A JP2009541269A5 JP 2009541269 A5 JP2009541269 A5 JP 2009541269A5 JP 2009515888 A JP2009515888 A JP 2009515888A JP 2009515888 A JP2009515888 A JP 2009515888A JP 2009541269 A5 JP2009541269 A5 JP 2009541269A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- phenoxy
- propyl
- phenyl
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *c1ccc(*NOc2cc(*)c(*)c(*)c2)c(*)c1 Chemical compound *c1ccc(*NOc2cc(*)c(*)c(*)c2)c(*)c1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0605540A FR2902789A1 (fr) | 2006-06-21 | 2006-06-21 | Derives de 1,3-diphenylpropane substitues, preparations et utilisations |
| FR0605540 | 2006-06-21 | ||
| PCT/EP2007/056224 WO2007147879A1 (fr) | 2006-06-21 | 2007-06-21 | Derives de 1,3-diphenylpropane substitues, preparations et utilisations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009541269A JP2009541269A (ja) | 2009-11-26 |
| JP2009541269A5 true JP2009541269A5 (https=) | 2010-08-12 |
| JP5350230B2 JP5350230B2 (ja) | 2013-11-27 |
Family
ID=37845179
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009515889A Expired - Fee Related JP5350231B2 (ja) | 2006-06-21 | 2007-06-21 | 置換された１，３−ジフェニルプロパン誘導体、その製造および使用 |
| JP2009515888A Active JP5350230B2 (ja) | 2006-06-21 | 2007-06-21 | 置換された１，３−ジフェニルプロパン誘導体、その製造および使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009515889A Expired - Fee Related JP5350231B2 (ja) | 2006-06-21 | 2007-06-21 | 置換された１，３−ジフェニルプロパン誘導体、その製造および使用 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8188148B2 (https=) |
| EP (2) | EP2046716B1 (https=) |
| JP (2) | JP5350231B2 (https=) |
| KR (2) | KR101416257B1 (https=) |
| CN (3) | CN104193660B (https=) |
| AU (2) | AU2007262938B2 (https=) |
| BR (1) | BRPI0713600B1 (https=) |
| CA (2) | CA2655744C (https=) |
| CY (2) | CY1115082T1 (https=) |
| DK (2) | DK2046715T5 (https=) |
| EA (1) | EA018437B1 (https=) |
| ES (2) | ES2434071T3 (https=) |
| FR (1) | FR2902789A1 (https=) |
| IL (2) | IL196071A0 (https=) |
| MX (1) | MX2008016239A (https=) |
| NO (1) | NO341866B1 (https=) |
| NZ (1) | NZ573674A (https=) |
| PL (2) | PL2046715T3 (https=) |
| PT (2) | PT2046716E (https=) |
| SI (2) | SI2046715T1 (https=) |
| WO (2) | WO2007147880A1 (https=) |
| ZA (1) | ZA200810709B (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2902789A1 (fr) * | 2006-06-21 | 2007-12-28 | Genfit Sa | Derives de 1,3-diphenylpropane substitues, preparations et utilisations |
| FR2917084B1 (fr) * | 2007-06-05 | 2009-07-17 | Galderma Res & Dev | Nouveaux derives d'acide 3-phenyl propanoique activateurs des recpteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques. |
| LT2641596T (lt) * | 2009-11-26 | 2018-08-10 | Genfit | 1,3-difenilprop-2-en-1-ono darinių panaudojimas kepenų sutrikimų gydymui |
| US10722575B2 (en) | 2009-11-26 | 2020-07-28 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
| US9221751B2 (en) | 2009-11-26 | 2015-12-29 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
| WO2011080276A1 (en) | 2009-12-29 | 2011-07-07 | Genfit | Pharmaceutical combinations comprising a dpp-4 inhibitor and a 1,3-diphenylprop-2-en-1-one derivative |
| EP2571843B1 (en) | 2010-05-17 | 2017-12-27 | Genfit | Improved preparation of chalcone derivatives |
| WO2012007365A1 (en) * | 2010-07-12 | 2012-01-19 | F. Hoffmann-La Roche Ag | 1-hydroxyimino-3-phenyl-propanes |
| BR112014011581A2 (pt) * | 2011-11-14 | 2017-05-09 | Hoffmann La Roche | 1-piridazinil-hidroxiimino-3-fenil-propanos como agonistas de gpbar1 |
| EA031899B9 (ru) * | 2011-12-28 | 2019-08-30 | Жанфит | Производные 1,3-дифенилпропана, их получение и применение |
| WO2017143038A1 (en) * | 2016-02-16 | 2017-08-24 | Concert Pharmaceuticals, Inc. | Deuterated gft-505 |
| US12053445B2 (en) | 2016-03-31 | 2024-08-06 | Genfit | Methods of treatment of cholestatic diseases |
| IT201600098338A1 (it) | 2016-09-30 | 2018-03-30 | Univ Degli Studi Padova | Composti 1-fenilpropanone e loro impiego |
| RU186145U1 (ru) * | 2018-08-08 | 2019-01-11 | Общество с ограниченной ответственностью "Научно-производственное объединение "Центротех" (ООО "НПО "Центротех") | Каркас виброрамы вибросита |
| US11634387B2 (en) | 2019-09-26 | 2023-04-25 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| MX2022009776A (es) | 2020-02-10 | 2022-09-09 | Genfit | Tratamiento de la colangitis biliar primaria con elafibranor. |
| CN114901641B (zh) * | 2020-02-28 | 2025-06-17 | 四川科伦博泰生物医药股份有限公司 | 芳香族化合物及其药物组合物和用途 |
| JP2023526410A (ja) * | 2020-05-18 | 2023-06-21 | ジェンフィット | 原発性硬化性胆管炎の治療のためのエラフィブラノール |
| CN115884765A (zh) | 2020-08-26 | 2023-03-31 | 基恩菲特公司 | 用于治疗原发性胆汁性胆管炎的组合物和方法 |
| JP2024519337A (ja) | 2021-05-11 | 2024-05-10 | ジェンフィット | 敗血症の治療において使用するためのｐｐａｒのエラフィブラノール誘導体アゴニスト |
| AU2022274304A1 (en) | 2021-05-11 | 2023-10-26 | Genfit | Ppar-agonists for use in the treatment of liver failure |
| TW202527918A (zh) | 2023-10-13 | 2025-07-16 | 法商Ｇｅｎｆｉｔ公司 | 原發性膽汁性膽管炎之治療方法 |
| WO2025088067A1 (en) | 2023-10-25 | 2025-05-01 | Genfit | Elafibranor for the treatment of primary biliary cholangitis |
| WO2025215081A1 (en) | 2024-04-09 | 2025-10-16 | Genfit | Elafibranor for use for long-term treatment of primary biliary cholangitis |
| WO2026047132A1 (en) | 2024-08-29 | 2026-03-05 | Genfit | Treatment of advanced primary biliary cholangitis |
| CN119490528A (zh) * | 2025-01-17 | 2025-02-21 | 山东第一医科大学附属肿瘤医院(山东省肿瘤防治研究院、山东省肿瘤医院) | 一种HSP90α选择性抑制剂及其合成方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2149070C3 (de) | 1971-10-01 | 1978-03-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Phenoxyalkylcarbonsäurederivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel |
| HU200591B (en) * | 1986-07-11 | 1990-07-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing new diphenyl propylamine derivatives and pharmaceutical compositions comprising such compounds |
| DE4121849A1 (de) * | 1991-07-02 | 1993-01-14 | Rhone Poulenc Rorer Gmbh | (4-((omega)-arylalkyl)-phenyl)alkansaeuren, ihre salze und/oder ihre derivate |
| DE4327365A1 (de) * | 1993-08-14 | 1995-02-16 | Boehringer Mannheim Gmbh | Verwendung von Phenolen und Phenolderivaten als Arzneimittel mit fibrinogensenkender Wirkung |
| YU72201A (sh) * | 1999-04-28 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | Derivati di-aril kiseline kao ppar receptorski ligandi |
| DE19933421A1 (de) * | 1999-07-16 | 2001-01-25 | Gruenenthal Gmbh | 2-Benzyl-3-dimethylamino-1-phenyl-propanderi- vate |
| FR2841900B1 (fr) | 2002-07-08 | 2007-03-02 | Genfit S A | Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations |
| MXPA06003019A (es) * | 2003-10-28 | 2006-06-23 | Reddys Lab Ltd Dr | Nuevos compuestos y su uso en medicina: proceso para su preparacion y composiciones farmaceuticas que los contienen. |
| MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| FR2902789A1 (fr) | 2006-06-21 | 2007-12-28 | Genfit Sa | Derives de 1,3-diphenylpropane substitues, preparations et utilisations |
-
2006
- 2006-06-21 FR FR0605540A patent/FR2902789A1/fr not_active Withdrawn
-
2007
- 2007-06-21 WO PCT/EP2007/056225 patent/WO2007147880A1/fr not_active Ceased
- 2007-06-21 CN CN201410016196.3A patent/CN104193660B/zh active Active
- 2007-06-21 PL PL07730296T patent/PL2046715T3/pl unknown
- 2007-06-21 KR KR1020097001318A patent/KR101416257B1/ko not_active Expired - Fee Related
- 2007-06-21 AU AU2007262938A patent/AU2007262938B2/en active Active
- 2007-06-21 JP JP2009515889A patent/JP5350231B2/ja not_active Expired - Fee Related
- 2007-06-21 US US12/308,558 patent/US8188148B2/en not_active Expired - Fee Related
- 2007-06-21 EP EP07786798.4A patent/EP2046716B1/fr active Active
- 2007-06-21 SI SI200731453T patent/SI2046715T1/sl unknown
- 2007-06-21 MX MX2008016239A patent/MX2008016239A/es active IP Right Grant
- 2007-06-21 CN CN2007800310203A patent/CN101506139B/zh not_active Expired - Fee Related
- 2007-06-21 ES ES07786798T patent/ES2434071T3/es active Active
- 2007-06-21 CA CA2655744A patent/CA2655744C/fr active Active
- 2007-06-21 BR BRPI0713600-5A patent/BRPI0713600B1/pt not_active IP Right Cessation
- 2007-06-21 PT PT77867984T patent/PT2046716E/pt unknown
- 2007-06-21 DK DK07730296.6T patent/DK2046715T5/da active
- 2007-06-21 KR KR1020097001319A patent/KR101416262B1/ko active Active
- 2007-06-21 PT PT77302966T patent/PT2046715E/pt unknown
- 2007-06-21 CN CN200780030962.XA patent/CN101506138B/zh active Active
- 2007-06-21 NZ NZ573674A patent/NZ573674A/en not_active IP Right Cessation
- 2007-06-21 US US12/308,580 patent/US8258182B2/en active Active
- 2007-06-21 ES ES07730296.6T patent/ES2466268T3/es active Active
- 2007-06-21 WO PCT/EP2007/056224 patent/WO2007147879A1/fr not_active Ceased
- 2007-06-21 EP EP07730296.6A patent/EP2046715B1/fr active Active
- 2007-06-21 DK DK07786798.4T patent/DK2046716T3/da active
- 2007-06-21 CA CA2655643A patent/CA2655643C/fr active Active
- 2007-06-21 JP JP2009515888A patent/JP5350230B2/ja active Active
- 2007-06-21 PL PL07786798T patent/PL2046716T3/pl unknown
- 2007-06-21 AU AU2007262939A patent/AU2007262939B2/en not_active Ceased
- 2007-06-21 EA EA200900044A patent/EA018437B1/ru not_active IP Right Cessation
- 2007-06-21 SI SI200731347T patent/SI2046716T1/sl unknown
-
2008
- 2008-12-18 IL IL196071A patent/IL196071A0/en active IP Right Grant
- 2008-12-18 IL IL196057A patent/IL196057A/en active IP Right Grant
- 2008-12-19 ZA ZA200810709A patent/ZA200810709B/xx unknown
- 2008-12-19 NO NO20085338A patent/NO341866B1/no not_active IP Right Cessation
-
2013
- 2013-10-30 CY CY20131100955T patent/CY1115082T1/el unknown
-
2014
- 2014-05-27 CY CY20141100379T patent/CY1115414T1/el unknown
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