JP2005534672A5 - - Google Patents
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- Publication number
- JP2005534672A5 JP2005534672A5 JP2004514761A JP2004514761A JP2005534672A5 JP 2005534672 A5 JP2005534672 A5 JP 2005534672A5 JP 2004514761 A JP2004514761 A JP 2004514761A JP 2004514761 A JP2004514761 A JP 2004514761A JP 2005534672 A5 JP2005534672 A5 JP 2005534672A5
- Authority
- JP
- Japan
- Prior art keywords
- oxy
- phenyl
- pyridinyl
- acetic acid
- pentyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0214149.7A GB0214149D0 (en) | 2002-06-19 | 2002-06-19 | Chemical compounds |
| PCT/EP2003/006415 WO2004000315A1 (en) | 2002-06-19 | 2003-06-18 | Phenylalkanoic acid and phenyloxyalkanoic acid derivatives as hppar activators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005534672A JP2005534672A (ja) | 2005-11-17 |
| JP2005534672A5 true JP2005534672A5 (https=) | 2006-06-15 |
Family
ID=9938916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004514761A Pending JP2005534672A (ja) | 2002-06-19 | 2003-06-18 | ｈＰＰＡＲ活性化物質としてのフェニルアルカン酸及びフェニルオキシアルカン酸誘導体 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7338960B2 (https=) |
| EP (1) | EP1513526B1 (https=) |
| JP (1) | JP2005534672A (https=) |
| KR (1) | KR20050030624A (https=) |
| CN (1) | CN1674897A (https=) |
| AT (1) | ATE377420T1 (https=) |
| AU (1) | AU2003245962B2 (https=) |
| BR (1) | BR0311931A (https=) |
| CA (1) | CA2487909A1 (https=) |
| CY (1) | CY1107168T1 (https=) |
| DE (1) | DE60317326T2 (https=) |
| DK (1) | DK1513526T3 (https=) |
| ES (1) | ES2295601T3 (https=) |
| GB (1) | GB0214149D0 (https=) |
| IL (1) | IL165476A0 (https=) |
| IS (1) | IS7574A (https=) |
| MX (1) | MXPA04012857A (https=) |
| NO (1) | NO20045328L (https=) |
| NZ (1) | NZ537210A (https=) |
| PL (1) | PL375148A1 (https=) |
| PT (1) | PT1513526E (https=) |
| RU (1) | RU2323929C2 (https=) |
| SI (1) | SI1513526T1 (https=) |
| WO (1) | WO2004000315A1 (https=) |
| ZA (1) | ZA200410061B (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7244763B2 (en) | 2003-04-17 | 2007-07-17 | Warner Lambert Company Llc | Compounds that modulate PPAR activity and methods of preparation |
| WO2005042478A2 (en) | 2003-09-19 | 2005-05-12 | Janssen Pharmaceutica, N.V. | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| AU2004291262C1 (en) | 2003-11-05 | 2011-08-11 | F. Hoffmann-La Roche Ag | Phenyl derivatives as PPAR agonists |
| AU2004309271A1 (en) | 2003-12-25 | 2005-07-14 | Takeda Pharmaceutical Company Limited | 3-(4-benzyloxyphenyl)propanoic acid derivatives |
| CA2558585C (en) * | 2004-02-27 | 2010-10-12 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders |
| AR048523A1 (es) * | 2004-04-07 | 2006-05-03 | Kalypsys Inc | Compuestos con estructura de aril sulfonamida y sulfonilo como moduladores de ppar y metodos para tratar trastornos metabolicos |
| WO2005105736A1 (en) | 2004-05-05 | 2005-11-10 | Novo Nordisk A/S | Novel compounds, their preparation and use |
| ES2352085T3 (es) | 2004-05-05 | 2011-02-15 | High Point Pharmaceuticals, Llc | Nuevos compuestos, su preparación y uso. |
| MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| US7465804B2 (en) * | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| ATE529404T1 (de) | 2005-06-30 | 2011-11-15 | High Point Pharmaceuticals Llc | Phenoxyessigsäuren als ppar-delta-aktivatoren |
| JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| EP1924546A1 (en) * | 2005-09-14 | 2008-05-28 | Amgen, Inc | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| BRPI0620468A2 (pt) | 2005-12-22 | 2011-11-08 | Transtech Pharma, Inc. | ácidos fenóxi acéticos como ativadores de ppar delta |
| WO2007101864A2 (en) | 2006-03-09 | 2007-09-13 | High Point Pharmaceuticals, Llc | Compounds that modulate ppar activity, their preparation and use |
| MX2008011615A (es) * | 2006-03-14 | 2008-09-22 | Amgen Inc | Derivados de acidos carboxilicos biciclicos utiles para tratar trastornos metabolicos. |
| PE20080188A1 (es) | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
| CN101591227B (zh) * | 2006-06-23 | 2012-09-05 | 赵昱 | 一类肉桂醇类衍生物及其制备方法和药物用途 |
| CA2662242C (en) | 2006-09-07 | 2012-06-12 | Amgen Inc. | Benzo-fused compounds for use in treating metabolic disorders |
| EP2064193A1 (en) * | 2006-09-07 | 2009-06-03 | Amgen, Inc | Heterocyclic gpr40 modulators |
| CN101595089A (zh) * | 2006-12-02 | 2009-12-02 | 财团法人首尔大学校产学协力财团 | 作为ppar配体的芳基化合物及其用途 |
| AU2008241490B2 (en) | 2007-04-16 | 2011-07-21 | Amgen Inc. | Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid GPR40 modulators |
| WO2009012650A1 (en) * | 2007-07-25 | 2009-01-29 | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. | Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof |
| US8030354B2 (en) | 2007-10-10 | 2011-10-04 | Amgen Inc. | Substituted biphenyl GPR40 modulators |
| WO2009111056A1 (en) | 2008-03-06 | 2009-09-11 | Amgen Inc. | Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders |
| AU2009303475B2 (en) * | 2008-10-15 | 2012-09-13 | Amgen Inc. | Spirocyclic GPR40 modulators |
| EP2699569B1 (en) * | 2011-04-22 | 2017-08-30 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| KR20140138243A (ko) | 2012-02-28 | 2014-12-03 | 피라말 엔터프라이지즈 리미티드 | G 단백질 연결 수용체 작용물질로서의 페닐알칸산 유도체 |
| KR101569522B1 (ko) | 2013-04-18 | 2015-11-17 | 현대약품 주식회사 | 신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물 |
| WO2015035171A1 (en) | 2013-09-09 | 2015-03-12 | High Point Pharmaceuticals, Llc | Use of a ppar-delta agonist for treating muscle atrophy |
| CN108503581A (zh) * | 2018-04-12 | 2018-09-07 | 苏州康润医药有限公司 | 一种3-溴-6-氟-2-吡啶乙酮的合成方法 |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS175831B1 (https=) * | 1974-12-17 | 1977-05-31 | ||
| FR2401459A1 (fr) * | 1977-08-26 | 1979-03-23 | Cii Honeywell Bull | Support d'information portatif muni d'un microprocesseur et d'une memoire morte programmable |
| DE4038335A1 (de) * | 1990-12-01 | 1992-06-04 | Boehringer Mannheim Gmbh | Neue pyridinderivate, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| CN1233241A (zh) * | 1996-08-19 | 1999-10-27 | 日本烟草产业株式会社 | 丙酸衍生物及其用途 |
| WO1999011255A1 (en) * | 1997-08-28 | 1999-03-11 | Ono Pharmaceutical Co., Ltd. | Peroxisome proliferator-activated receptor controllers |
| ATE451346T1 (de) * | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| US6586475B1 (en) * | 1998-11-20 | 2003-07-01 | Takeda Chemical Industries, Ltd. | β-amyloid protein production/secretion inhibitors |
| PL351470A1 (en) * | 1999-04-28 | 2003-04-22 | Aventis Pharma Gmbh | Tri-aryl acid derivatives as ppar receptor ligands |
| US6677473B1 (en) * | 1999-11-19 | 2004-01-13 | Corvas International Inc | Plasminogen activator inhibitor antagonists |
| CA2407088A1 (en) * | 2000-05-19 | 2001-11-22 | Takeda Chemical Industries, Ltd. | Beta-secretase inhibitors |
-
2002
- 2002-06-19 GB GBGB0214149.7A patent/GB0214149D0/en not_active Ceased
-
2003
- 2003-06-18 BR BR0311931-9A patent/BR0311931A/pt not_active IP Right Cessation
- 2003-06-18 PT PT03738056T patent/PT1513526E/pt unknown
- 2003-06-18 EP EP03738056A patent/EP1513526B1/en not_active Expired - Lifetime
- 2003-06-18 SI SI200331089T patent/SI1513526T1/sl unknown
- 2003-06-18 JP JP2004514761A patent/JP2005534672A/ja active Pending
- 2003-06-18 PL PL03375148A patent/PL375148A1/xx not_active Application Discontinuation
- 2003-06-18 US US10/518,679 patent/US7338960B2/en not_active Expired - Fee Related
- 2003-06-18 DK DK03738056T patent/DK1513526T3/da active
- 2003-06-18 CN CNA03819290XA patent/CN1674897A/zh active Pending
- 2003-06-18 AU AU2003245962A patent/AU2003245962B2/en not_active Ceased
- 2003-06-18 WO PCT/EP2003/006415 patent/WO2004000315A1/en not_active Ceased
- 2003-06-18 NZ NZ537210A patent/NZ537210A/en unknown
- 2003-06-18 MX MXPA04012857A patent/MXPA04012857A/es active IP Right Grant
- 2003-06-18 AT AT03738056T patent/ATE377420T1/de not_active IP Right Cessation
- 2003-06-18 KR KR1020047020583A patent/KR20050030624A/ko not_active Ceased
- 2003-06-18 IL IL16547603A patent/IL165476A0/xx unknown
- 2003-06-18 CA CA002487909A patent/CA2487909A1/en not_active Abandoned
- 2003-06-18 RU RU2004135539/04A patent/RU2323929C2/ru not_active IP Right Cessation
- 2003-06-18 ES ES03738056T patent/ES2295601T3/es not_active Expired - Lifetime
- 2003-06-18 DE DE60317326T patent/DE60317326T2/de not_active Expired - Fee Related
-
2004
- 2004-11-30 IS IS7574A patent/IS7574A/is unknown
- 2004-12-03 NO NO20045328A patent/NO20045328L/no not_active Application Discontinuation
- 2004-12-13 ZA ZA200410061A patent/ZA200410061B/en unknown
-
2008
- 2008-01-31 CY CY20081100116T patent/CY1107168T1/el unknown
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