JP2009538866A5 - - Google Patents
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- Publication number
- JP2009538866A5 JP2009538866A5 JP2009512568A JP2009512568A JP2009538866A5 JP 2009538866 A5 JP2009538866 A5 JP 2009538866A5 JP 2009512568 A JP2009512568 A JP 2009512568A JP 2009512568 A JP2009512568 A JP 2009512568A JP 2009538866 A5 JP2009538866 A5 JP 2009538866A5
- Authority
- JP
- Japan
- Prior art keywords
- diaza
- bicyclo
- alkyl
- phenyl
- oxadiazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80902406P | 2006-05-30 | 2006-05-30 | |
| DKPA200600731 | 2006-05-30 | ||
| PCT/EP2007/055168 WO2007138037A1 (en) | 2006-05-30 | 2007-05-29 | Novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their medical use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009538866A JP2009538866A (ja) | 2009-11-12 |
| JP2009538866A5 true JP2009538866A5 (https=) | 2010-04-15 |
Family
ID=40616686
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009512569A Expired - Fee Related JP5290964B2 (ja) | 2006-05-30 | 2007-05-29 | 新規１，４−ジアザ−ビシクロ［３．２．２］ノニルオキサジアゾリル誘導体及びそれらの医学的使用 |
| JP2009512568A Pending JP2009538866A (ja) | 2006-05-30 | 2007-05-29 | 新規１，４−ジアザ−ビシクロ［３．２．２］ノニルオキサジアゾリル誘導体及びそれらの医学的使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009512569A Expired - Fee Related JP5290964B2 (ja) | 2006-05-30 | 2007-05-29 | 新規１，４−ジアザ−ビシクロ［３．２．２］ノニルオキサジアゾリル誘導体及びそれらの医学的使用 |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US8158619B2 (https=) |
| EP (3) | EP2032575B1 (https=) |
| JP (2) | JP5290964B2 (https=) |
| KR (1) | KR101458194B1 (https=) |
| CN (2) | CN101432286A (https=) |
| AT (3) | ATE463497T1 (https=) |
| AU (2) | AU2007267174B2 (https=) |
| BR (1) | BRPI0708843A2 (https=) |
| CA (2) | CA2653769A1 (https=) |
| DE (2) | DE602007005802D1 (https=) |
| DK (2) | DK2032574T3 (https=) |
| ES (1) | ES2342334T3 (https=) |
| IL (1) | IL193925A (https=) |
| MX (2) | MX2008014887A (https=) |
| MY (1) | MY147764A (https=) |
| NO (1) | NO20085398L (https=) |
| NZ (1) | NZ571288A (https=) |
| PL (1) | PL2032575T3 (https=) |
| PT (1) | PT2032575E (https=) |
| RU (1) | RU2427581C2 (https=) |
| UA (1) | UA95946C2 (https=) |
| WO (2) | WO2007138038A1 (https=) |
| ZA (1) | ZA200807756B (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8158619B2 (en) | 2006-05-30 | 2012-04-17 | Neurosearch A/S | 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl compounds and their medical use |
| EP2079734A1 (en) * | 2006-10-25 | 2009-07-22 | NeuroSearch A/S | Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
| JP2010536726A (ja) | 2007-08-17 | 2010-12-02 | ノイロサーチ アクティーゼルスカブ | ニコチン性アセチルコリン受容体リガンドとして有用な新規１，４−ジアザ−ビシクロ〔３．２．２〕ノニルヘテロアリール誘導体 |
| CN101952288A (zh) | 2008-03-11 | 2011-01-19 | 神经研究公司 | 可用作烟碱乙酰胆碱受体的调节剂的新颖的1,4-二氮杂-双环[3.2.2]壬基二唑基衍生物 |
| EP2288608A1 (en) * | 2008-06-10 | 2011-03-02 | NeuroSearch A/S | Novel oxadiazolyl-diazabicyclononane derivatives and their medical use |
| WO2010043539A1 (en) * | 2008-10-13 | 2010-04-22 | Neurosearch A/S | Novel oxadiazolyl-diazabicyclononane derivatives and their medical use |
| WO2010063784A1 (en) * | 2008-12-04 | 2010-06-10 | Neurosearch A/S | Novel diaza-bicyclononyl-phenyl derivatives and their medical use |
| MX2011007449A (es) | 2009-01-26 | 2011-10-24 | Neurosearch As | Derivados de indolil-oxadiazolil-diazabiciclononano y su uso medico y diagnostico. |
| WO2010086280A1 (en) | 2009-01-27 | 2010-08-05 | Neurosearch A/S | Novel n-oxides of furanyl-oxadiazolyl-diazabicyclononane derivatives and their medical use |
| US20120028968A1 (en) | 2009-01-27 | 2012-02-02 | Neurosearch A/S | Novel dibenzofuranyl-oxadiazolyl-diazabicyclononane derivatives and their medical use |
| WO2010086278A1 (en) | 2009-01-27 | 2010-08-05 | Neurosearch A/S | Novel benzodioxolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use |
| US20120071469A1 (en) * | 2009-05-14 | 2012-03-22 | Neurosearch A/S | Novel 1,4-diaza-bicyclo[3.2.1]octane derivatives useful as nicotinic acetylcholine receptor modulators |
| JO3250B1 (ar) | 2009-09-22 | 2018-09-16 | Novartis Ag | إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7 |
| US20120288443A1 (en) | 2009-11-11 | 2012-11-15 | Neurosearch A/S | Labelled pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their use in diagnostic methods |
| EP2513097A1 (en) | 2009-12-18 | 2012-10-24 | NeuroSearch AS | Diazabicyclononyl oxadiazole compounds and their use as nicotinic acetylcholine receptor modulators |
| US8986654B2 (en) | 2011-04-15 | 2015-03-24 | Danpet Ab | Labelled and un-labelled methyl-pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use |
| JP7312749B2 (ja) | 2017-08-04 | 2023-07-21 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングをモジュレートする方法および組成物 |
| CR20200553A (es) | 2018-04-18 | 2021-04-08 | Constellation Pharmaceuticals Inc | Moduladores de enzimas modificadoras de metilo, composiciones y usos de estos |
| CN120097995A (zh) | 2018-05-21 | 2025-06-06 | 星座制药公司 | 甲基修饰酶的调节剂、其组合物和用途 |
| EP3920910A4 (en) * | 2019-02-04 | 2022-11-09 | Skyhawk Therapeutics, Inc. | METHODS AND COMPOSITIONS FOR MODULATION OF SPLICING |
| JP7551629B2 (ja) | 2019-02-05 | 2024-09-17 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| WO2020163405A1 (en) | 2019-02-05 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| JP7603595B2 (ja) | 2019-02-06 | 2024-12-20 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| JP7603594B2 (ja) | 2019-02-06 | 2024-12-20 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| WO2021016414A1 (en) | 2019-07-24 | 2021-01-28 | Constellation Pharmaceuticals, Inc. | Crystalline forms of 7-chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2,4-dimethyl-n-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646289A (en) * | 1994-10-24 | 1997-07-08 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
| FR2809732B1 (fr) * | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE |
| FR2809731B1 (fr) | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique |
| FR2832712B1 (fr) | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique |
| FR2832713B1 (fr) | 2001-11-23 | 2004-02-13 | Sanofi Synthelabo | Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique |
| MXPA05003344A (es) * | 2002-09-30 | 2005-11-23 | Neurosearch As | Derivados novedosos de 1,4-diazabicicloalcano, su preparacion y uso. |
| US7220741B2 (en) * | 2002-09-30 | 2007-05-22 | Neurosearch A/S | 1,4-diazabicycloalkane derivatives, their preparation and use |
| DK1562945T3 (da) * | 2002-11-11 | 2007-03-05 | Neurosearch As | Hidtil ukendte diazebicykliske biarylderivater |
| US6996399B2 (en) * | 2003-01-13 | 2006-02-07 | Micrel, Inc. | Wireless device and method using frequency hopping and sweep modes |
| ATE450263T1 (de) * | 2004-02-04 | 2009-12-15 | Neurosearch As | Diazabicyclische aryl-derivate als cholinerge rezeptor-modulatoren |
| WO2006087306A2 (en) | 2005-02-16 | 2006-08-24 | Neurosearch A/S | Diazabicyclic aryl derivatives and their use as cholinergic ligands at the nicotinic acetylcholine receptors |
| US8158619B2 (en) | 2006-05-30 | 2012-04-17 | Neurosearch A/S | 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl compounds and their medical use |
-
2007
- 2007-05-29 US US12/297,333 patent/US8158619B2/en not_active Expired - Fee Related
- 2007-05-29 UA UAA200811110A patent/UA95946C2/ru unknown
- 2007-05-29 DK DK07729590.5T patent/DK2032574T3/da active
- 2007-05-29 DE DE602007005802T patent/DE602007005802D1/de active Active
- 2007-05-29 CA CA002653769A patent/CA2653769A1/en not_active Abandoned
- 2007-05-29 RU RU2008139481/04A patent/RU2427581C2/ru not_active IP Right Cessation
- 2007-05-29 US US12/300,060 patent/US7807667B2/en not_active Expired - Fee Related
- 2007-05-29 MX MX2008014887A patent/MX2008014887A/es active IP Right Grant
- 2007-05-29 AU AU2007267174A patent/AU2007267174B2/en not_active Expired - Fee Related
- 2007-05-29 CA CA002653818A patent/CA2653818A1/en not_active Abandoned
- 2007-05-29 JP JP2009512569A patent/JP5290964B2/ja not_active Expired - Fee Related
- 2007-05-29 AT AT07729591T patent/ATE463497T1/de active
- 2007-05-29 ZA ZA200807756A patent/ZA200807756B/xx unknown
- 2007-05-29 AT AT10154049T patent/ATE518862T1/de not_active IP Right Cessation
- 2007-05-29 ES ES07729591T patent/ES2342334T3/es active Active
- 2007-05-29 BR BRPI0708843-4A patent/BRPI0708843A2/pt not_active IP Right Cessation
- 2007-05-29 DE DE602007006486T patent/DE602007006486D1/de active Active
- 2007-05-29 AT AT07729590T patent/ATE467634T1/de active
- 2007-05-29 EP EP07729591A patent/EP2032575B1/en not_active Not-in-force
- 2007-05-29 EP EP10154049A patent/EP2194056B1/en not_active Not-in-force
- 2007-05-29 WO PCT/EP2007/055169 patent/WO2007138038A1/en not_active Ceased
- 2007-05-29 MX MX2008014886A patent/MX2008014886A/es active IP Right Grant
- 2007-05-29 PL PL07729591T patent/PL2032575T3/pl unknown
- 2007-05-29 PT PT07729591T patent/PT2032575E/pt unknown
- 2007-05-29 NZ NZ571288A patent/NZ571288A/en not_active IP Right Cessation
- 2007-05-29 WO PCT/EP2007/055168 patent/WO2007138037A1/en not_active Ceased
- 2007-05-29 EP EP07729590A patent/EP2032574B1/en not_active Not-in-force
- 2007-05-29 DK DK07729591.3T patent/DK2032575T3/da active
- 2007-05-29 JP JP2009512568A patent/JP2009538866A/ja active Pending
- 2007-05-29 AU AU2007267175A patent/AU2007267175A1/en not_active Abandoned
- 2007-05-29 CN CNA200780015245XA patent/CN101432286A/zh active Pending
- 2007-05-29 KR KR1020087031858A patent/KR101458194B1/ko not_active Expired - Fee Related
- 2007-05-29 MY MYPI20084717A patent/MY147764A/en unknown
- 2007-05-29 CN CN200780014526.3A patent/CN101426790B/zh not_active Expired - Fee Related
-
2008
- 2008-09-04 IL IL193925A patent/IL193925A/en not_active IP Right Cessation
- 2008-12-29 NO NO20085398A patent/NO20085398L/no not_active Application Discontinuation
-
2010
- 2010-08-23 US US12/861,420 patent/US8101598B2/en not_active Expired - Fee Related
-
2012
- 2012-03-14 US US13/420,071 patent/US8372832B2/en not_active Expired - Fee Related
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