JP2009513519A - 血管作用剤の組合せ物、それらの薬剤および化粧品分野での使用、ならびにそれらを含む製剤 - Google Patents
血管作用剤の組合せ物、それらの薬剤および化粧品分野での使用、ならびにそれらを含む製剤 Download PDFInfo
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Abstract
Description
− ビスナジンまたはエスクロシド;
− イカリンまたはその誘導体またはそれを含む抽出物、遊離状態またはホスホリピドと錯体化した状態のイチョウ(Gingko biloba)の2量体フラボン、およびアメントフラボンから選ばれる少くとも1つの化合物;
− エスシン、ホスホリピドと錯体化したエスシンβ−シトステロール、セリコシド、ホスホリピドと錯体化したセリコシド、または遊離状態もしくはホスホリピドと錯体化したツボクサ(Centella asiatica)抽出物から選ばれる少くとも1つの化合物。
− ビスナジンまたはエスクロシド:0.05〜2%;
− アメントフラボン、または遊離状態もしくはホスホリピドと錯体化した状態のイチョウ(Gingko biloba)2量体:0.1〜1%;
− イカリンもしくはその誘導体またはそれを含む抽出物:0.1〜1%;
− エスシン、ホスホリピドと錯体化したエスシンβ−シトステロール、セリコシド、ホスホリピドと錯体化したセリコシド、または遊離状態もしくはホスホリピドと錯体化したツボクサ(Centella asiatica)抽出物、のうちから選ばれる少くとも1つの化合物:0.5〜2%。
ビスナジン 0.25g
7−ヒドロキシエチル−7−デスグルコ−イカリン 0.35g
アメントフラボン 0.25g
エスシン 1.00g
レシチン 20.00g
コレステロール 0.50g
エタノール 8.00g
ブチルヒドロキシトルエン 0.01g
イミダゾリン尿素 0.30g
ヒドロキシプロピル−メチルセルロース 2.00g
水 十分な量で100gにする。
エスクロシド 1.00g
イカリン 0.35g
アメントフラボン 0.25g
エスシン 1.00g
レシチン 20.00g
コレステロール 0.50g
エタノール 8.00g
ブチルヒドロキシトルエン 0.01g
イミダゾリン尿素 0.30g
ヒドロキシプロピル−メチルセルロース 2.00g
水 十分量で100gにする。
ビスナジン 0.25g
7−ヒドロキシエチル−7−デスグルコ−イカリン 0.35g
ホスホリピドと錯体化したイチョウ2量体 0.25g
ホスホリピドと錯体化したエスシンβ−シトステロール 1.00g
レシチン 20.00g
コレステロール 0.50g
エタノール 8.00g
ブチルヒドロキシトルエン 0.01g
イミダゾリン尿素 0.30g
ヒドロキシプロピル−メチルセルロース 2.00g
水 100gにする十分量
エスクロシド 0.25g
7−ヒドロキシエチル−7−デスグルコ−イカリン 0.35g
アメントフラボン 0.25g
セリコシド 1.00g
レシチン 20.00g
コレステロール 0.50g
エタノール 8.00g
ブチルヒドロキシトルエン 0.01g
イミダゾリン尿素 0.30g
ヒドロキシプロピル−メチルセルロース 2.00g
水 100gにする十分量
ビスナジン 0.3g
アメントフラボン 0.4g
Centella asiatica抽出物 1.0g
レシチン 20.00g
コレステロール 0.50g
エタノール 8.00g
ブチルヒドロキシトルエン 0.01g
イミダゾリン尿素 0.30g
ヒドロキシプロピル−メチルセルロース 2.00g
水 qb 100g
Claims (11)
- 以下のものを含む薬剤、化粧品、ダイエット食品、または営養補給物用組成物:
− ビスナジンまたはエスクロシド;
− イカリンまたはその誘導体またはイカリンを含む抽出物、遊離状態またはホスホリピドと錯体化した状態のいずれかであるイチョウ2量体フラボン、アメントフラボンから選ばれる少くとも1つの化合物;
− エスシン、ホスホリピドと錯体化したエスシンベータ−シトステロール、セリコシド、ホスホリピドと錯体化したセリコシドまたは遊離状態もしくはホスホリピドと錯体化した状態のツボクサ抽出物から選ばれる少くとも1つの化合物。 - 重量基準で次の濃度範囲を有する、請求項1記載の組成物:
− ビスナジンまたはエスクロシド:0.05〜2%;
− アメントフラボンまたは遊離状態もしくはホスホリピドと錯体化したイチョウ2量体フラボン:0.1〜1%;
− イカリンまたはその誘導体、またはそれを含む抽出物:0.1〜1%;
− エスシン、ホスホリピドと錯体化したエスシンベータ−シトステロール、または遊離状態もしくはホスホリピドと錯体化したツボクサ抽出物:0.5〜2% - イカリン誘導体が7−ヒドロキシエチル−イカリン、7−エチルアミノ−イカリン、7−アミノエチル−イカリン、7−ヒドロキシエチル−3−0−ラムノシル−イカリン、7−アミノエチル−3−ラムノシル−イカリン、8−ジヒドロ−イカリンおよびその7−および3−のグルコシド、および7−ヒドロキシエチル−7−デスグルコ−イカリンを含む、請求項1または2記載の組成物。
- クリーム、ゲル、ローション、ミルクの形態である、請求項1ないし3のいずれか1項に記載の組成物。
- ビスナジンを含む、請求項1記載の組成物。
- ビスナジン、7−ヒドロキシエチル−7−デスグルコ−イアリン、アメントフラボン、およびエスシンを含む、請求項1記載の組成物。
- エスクロシド、イカリン、アメントフラボン、エスシンを含む、請求項1記載の組成物。
- ビスナジン、7−ヒドロキシエチル−7−デスグルコ−イカリン、遊離状態またはホスホリピドと錯体化したイチョウ2量体を含む、請求項1記載の組成物。
- ビスナジン、ホスホリピドと錯体化したイチョウ2量体、ホスホリピドと錯体化したエスシンベータ−シトステロールを含む、請求項1記載の組成物。
- エスクロシド、ホスホリピドと錯体化したイチョウ2量体、ホスホリピドと錯体化したエスシンベータ−シトステロールを含む、請求項1記載の組成物。
- 以下の組合せ物のパニクロパシーおよび下肢の静脈血不足と関連する疾患の治療用組成物の製造のための使用:
− ビスナジンまたはエスクロシド;
− イカリンまたはその誘導体またはそれを含む抽出物、遊離状態またはホスホリピドと錯体化した状態のイチョウ2量体フラボン、アメントフラボンから選ばれる少くとも1つの化合物;
− エスシン、ホスホリピドと錯体化したエスシンベータ−シトステロール、セリコシド、ホスホリピドと錯体化したセリコシド、または遊離状態もしくはホスホリピドと錯体化したツボクサ抽出物から選ばれる少くとも1つの化合物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2003A001427 | 2003-07-11 | ||
IT001427A ITMI20031427A1 (it) | 2003-07-11 | 2003-07-11 | Combinazioni di agenti vasoattivi, loro uso in campo farmaceutico e cosmetico e formulazioni che li contengono |
PCT/EP2004/007375 WO2005004858A1 (en) | 2003-07-11 | 2004-07-06 | Combinations of vasoactive agents, their use in the pharmaceutical and cosmetic field, and formulations containing them |
Publications (2)
Publication Number | Publication Date |
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JP2009513519A true JP2009513519A (ja) | 2009-04-02 |
JP4964590B2 JP4964590B2 (ja) | 2012-07-04 |
Family
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Application Number | Title | Priority Date | Filing Date |
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JP2006518124A Active JP4964590B2 (ja) | 2003-07-11 | 2004-07-06 | 血管作用剤の組合せ物、それらの薬剤および化粧品分野での使用、ならびにそれらを含む製剤 |
Country Status (20)
Country | Link |
---|---|
US (1) | US7976881B2 (ja) |
EP (2) | EP1658064B1 (ja) |
JP (1) | JP4964590B2 (ja) |
KR (2) | KR101166935B1 (ja) |
CN (1) | CN1819826A (ja) |
AT (1) | ATE455544T1 (ja) |
AU (1) | AU2004255442B2 (ja) |
BR (1) | BRPI0412365B8 (ja) |
CA (1) | CA2532828C (ja) |
DE (1) | DE602004025253D1 (ja) |
DK (2) | DK2158909T3 (ja) |
ES (2) | ES2335995T3 (ja) |
HU (1) | HUE032952T2 (ja) |
IT (1) | ITMI20031427A1 (ja) |
NO (1) | NO335285B1 (ja) |
PL (2) | PL2158909T3 (ja) |
PT (2) | PT1658064E (ja) |
RU (2) | RU2358726C2 (ja) |
SI (2) | SI1658064T1 (ja) |
WO (1) | WO2005004858A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008069132A (ja) * | 2006-09-15 | 2008-03-27 | Noevir Co Ltd | 痩身用組成物 |
JP2008532962A (ja) * | 2005-03-12 | 2008-08-21 | ユニリーバー・ナームローゼ・ベンノートシヤープ | ビスナジンを含む頭髪および/または頭皮ケア組成物 |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20031789A1 (it) * | 2003-09-19 | 2005-03-20 | Indena Spa | Composizioni farmaceutiche e cosmetiche per il trattamento |
ES2346900T3 (es) | 2005-03-12 | 2010-10-21 | Unilever N.V. | Composiciones para el cuidado del cabello y/o el cuero cabelludo que incorporan compuestos amino-oxo-indol-ilideno. |
KR20080025960A (ko) * | 2006-09-19 | 2008-03-24 | (주)아모레퍼시픽 | 이카리시드 ⅰⅰ의 제조 방법 및 이를 함유하는 미백용조성물 |
EP2011496A1 (en) * | 2007-07-03 | 2009-01-07 | Indena S.P.A. | Combinations of vasoactive substances with estrogens and their use in the treatment of female sexual dysfunctions |
FR2918885B1 (fr) | 2007-07-17 | 2009-08-28 | Oreal | Utilisation d'extrait de bacterie cultivee sur eau thermale pour diminuer les poches et/ou les cernes perioculaires |
ITMI20110373A1 (it) * | 2011-03-10 | 2012-09-11 | Erbolario S R L L | "composizioni cosmetiche per il trattamento degli inestetismi cutanei della cellulite" |
WO2015099521A2 (en) | 2013-12-24 | 2015-07-02 | Biotropics Malaysia Bhd | Fruit extracts and extract formulations of canarium odontophyllum as actives and related invention embodiments |
CN104387430B (zh) * | 2014-10-27 | 2017-03-15 | 广东东阳光药业有限公司 | 淫羊藿苷类化合物及其应用 |
RU2770422C1 (ru) * | 2021-02-18 | 2022-04-18 | Закрытое Акционерное Общество "Канонфарма Продакшн" | Фармацевтическая композиция в форме гидрогеля с венотонизирующим и ранозаживляющим действием |
Citations (7)
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JPS63277691A (ja) * | 1987-02-26 | 1988-11-15 | インデナ エス.ピー.エー. | サポニンとりん脂質との複合体及びそれらを含有する薬学的及び化粧用の組成物 |
JPH03145427A (ja) * | 1989-09-21 | 1991-06-20 | Indena Spa | 皮膚の微小循環に対して作用する薬剤組成物 |
JPH03167133A (ja) * | 1989-10-27 | 1991-07-19 | Indena Spa | 人体中の沈着脂肪を処理するための組成物 |
JPH0859463A (ja) * | 1994-07-26 | 1996-03-05 | Indena Spa | クマリンを含む調製物および薬剤および美容分野におけるそれらの使用 |
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JP2008532962A (ja) * | 2005-03-12 | 2008-08-21 | ユニリーバー・ナームローゼ・ベンノートシヤープ | ビスナジンを含む頭髪および/または頭皮ケア組成物 |
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