BRPI0412365A - combinações de agentes vasoativos, uso no campo farmacêutico das mesmas e cosmético e formulações contendo as mesmas - Google Patents

combinações de agentes vasoativos, uso no campo farmacêutico das mesmas e cosmético e formulações contendo as mesmas

Info

Publication number
BRPI0412365A
BRPI0412365A BRPI0412365-4A BRPI0412365A BRPI0412365A BR PI0412365 A BRPI0412365 A BR PI0412365A BR PI0412365 A BRPI0412365 A BR PI0412365A BR PI0412365 A BRPI0412365 A BR PI0412365A
Authority
BR
Brazil
Prior art keywords
phospholipids
complexed
combinations
pharmaceutical
same
Prior art date
Application number
BRPI0412365-4A
Other languages
English (en)
Inventor
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of BRPI0412365A publication Critical patent/BRPI0412365A/pt
Publication of BRPI0412365B1 publication Critical patent/BRPI0412365B1/pt
Publication of BRPI0412365B8 publication Critical patent/BRPI0412365B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof

Abstract

"COMBINAçõES DE AGENTES VASOATIVOS, USO NO CAMPO FARMACêUTICO DAS MESMAS E COSMéTICO E FORMULAçõES CONTENDO AS MESMAS". A presente invenção refere-se a combinações de substâncias vasoativas que agem no nível venoso ou arterial com inibidores de fosfodiesterase, incluindo fosfodiesterase V, em particular: visnadina ou esculosídeo; pelo menos um composto selecionado de icarin ou seus derivados ou extratos contendo-as, flavonas diméricas de Gingko biloba ou na forma livre ou complexadas com fosfolipídeos, amentoflavona; pelo menos um composto selecionado de escina, escina beta-sitosterol complexada com fosfolipídeos, sericosídeo, sericosídeo complexado com fosfolipídeos ou extrato de Centella asiatica na forma livre ou complexado com fosfolipídeos. As formulações de acordo com a invenção são úteis na redução de paniculopatia e dos problemas associados à insuficiência venosa dos membros inferiores.
BRPI0412365A 2003-07-11 2004-07-06 combinações de agentes vasoativos, uso no campo farmacêutico das mesmas e cosmético e formulações contendo as mesmas BRPI0412365B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001427A ITMI20031427A1 (it) 2003-07-11 2003-07-11 Combinazioni di agenti vasoattivi, loro uso in campo farmaceutico e cosmetico e formulazioni che li contengono
PCT/EP2004/007375 WO2005004858A1 (en) 2003-07-11 2004-07-06 Combinations of vasoactive agents, their use in the pharmaceutical and cosmetic field, and formulations containing them

Publications (3)

Publication Number Publication Date
BRPI0412365A true BRPI0412365A (pt) 2006-09-05
BRPI0412365B1 BRPI0412365B1 (pt) 2016-11-22
BRPI0412365B8 BRPI0412365B8 (pt) 2021-05-25

Family

ID=34044549

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0412365A BRPI0412365B8 (pt) 2003-07-11 2004-07-06 combinações de agentes vasoativos, uso no campo farmacêutico das mesmas e cosmético e formulações contendo as mesmas

Country Status (20)

Country Link
US (1) US7976881B2 (pt)
EP (2) EP1658064B1 (pt)
JP (1) JP4964590B2 (pt)
KR (2) KR101227788B1 (pt)
CN (1) CN1819826A (pt)
AT (1) ATE455544T1 (pt)
AU (1) AU2004255442B2 (pt)
BR (1) BRPI0412365B8 (pt)
CA (1) CA2532828C (pt)
DE (1) DE602004025253D1 (pt)
DK (2) DK2158909T3 (pt)
ES (2) ES2621505T3 (pt)
HU (1) HUE032952T2 (pt)
IT (1) ITMI20031427A1 (pt)
NO (1) NO335285B1 (pt)
PL (2) PL1658064T3 (pt)
PT (2) PT2158909T (pt)
RU (2) RU2358726C2 (pt)
SI (2) SI1658064T1 (pt)
WO (1) WO2005004858A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20031789A1 (it) * 2003-09-19 2005-03-20 Indena Spa Composizioni farmaceutiche e cosmetiche per il trattamento
JP5047940B2 (ja) 2005-03-12 2012-10-10 ユニリーバー・ナームローゼ・ベンノートシヤープ アミノ−オキソ−インドール−イリデン化合物を含む頭髪および／または頭皮ケア組成物
EP1915198B1 (en) * 2005-03-12 2011-04-06 Unilever PLC Visnadin for treating scalp skin itching
JP5179032B2 (ja) * 2006-09-15 2013-04-10 株式会社ノエビア 痩身用組成物
KR20080025960A (ko) * 2006-09-19 2008-03-24 (주)아모레퍼시픽 이카리시드 ⅰⅰ의 제조 방법 및 이를 함유하는 미백용조성물
EP2011496A1 (en) * 2007-07-03 2009-01-07 Indena S.P.A. Combinations of vasoactive substances with estrogens and their use in the treatment of female sexual dysfunctions
FR2918885B1 (fr) 2007-07-17 2009-08-28 Oreal Utilisation d'extrait de bacterie cultivee sur eau thermale pour diminuer les poches et/ou les cernes perioculaires
ITMI20110373A1 (it) * 2011-03-10 2012-09-11 Erbolario S R L L "composizioni cosmetiche per il trattamento degli inestetismi cutanei della cellulite"
WO2015099521A2 (en) 2013-12-24 2015-07-02 Biotropics Malaysia Bhd Fruit extracts and extract formulations of canarium odontophyllum as actives and related invention embodiments
CN104387430B (zh) * 2014-10-27 2017-03-15 广东东阳光药业有限公司 淫羊藿苷类化合物及其应用
RU2770422C1 (ru) * 2021-02-18 2022-04-18 Закрытое Акционерное Общество "Канонфарма Продакшн" Фармацевтическая композиция в форме гидрогеля с венотонизирующим и ранозаживляющим действием

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203515B (it) * 1987-02-26 1989-02-15 Indena Spa Complessi di saponine con fosfolipidi e composizioni farmaceutiche e cosmetiche che li contengono
IT1233753B (it) * 1989-09-21 1992-04-14 Indena Spa Composizioni farmaceutiche ad attivita' sulla microcircolazione cutanea.
IT1239281B (it) * 1989-10-27 1993-10-19 Indena Spa Composizioni per la riduzione dei depositi di grasso superfluo a base di principi attivi di origine vegetale ad attivita' agonista dell'adenilato ciclasi o/e ad attivita' antifosfodiesterasica
IT1269634B (it) 1994-05-06 1997-04-08 Indena Spa Medicamento topico ad attivita' cicatrizzante
IT1270602B (it) * 1994-07-12 1997-05-07 Indena Spa Formulazioni a base di esculoside e loro uso in campo farmaceutico e cosmetico
IT1278997B1 (it) * 1994-07-19 1997-12-02 Indena Spa Combinazioni di sostanze vasoattive con acidi grassi per combattere la caduta dei capelli
IT1270999B (it) * 1994-07-26 1997-05-26 Indena Spa Formulazioni a base di cumarine e loro uso in campo farmaceutico e cosmetico
US5529769A (en) * 1994-12-20 1996-06-25 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Cosmetic compositions containing betulinic acid
US5523090A (en) * 1995-02-24 1996-06-04 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin treatment composition
FR2740681B1 (fr) * 1995-11-07 1998-01-23 Fabre Pierre Dermo Cosmetique Composition cosmetique a base d'un extrait de viburnum
US6267996B1 (en) * 1996-10-17 2001-07-31 Indena S.P.A Pharmaceutical and cosmetic formulations with antimicrobial activity
PT1032361E (pt) * 1997-11-19 2002-09-30 Flavone Sunproducts As Composicao compreendendo um ou mais flavonoides metodo para a obtencao dessa composicao e sua utilizacao como agente absorvente de uv
US20020013280A1 (en) * 2000-06-16 2002-01-31 Zhongcheng Xin Pharmaceutical composition for preventing and treating sexual dysfunction and vasculargenic disease comprising icariin
KR100394329B1 (ko) * 1999-06-17 2003-08-09 북경동방백오의약개발유한공사 성기능장애 및 혈관계질환의 치료용 약제학적 조성물
WO2001078674A1 (en) * 2000-04-18 2001-10-25 Ceteris Holding B.V. -Amsterdam (Olanda)- Succursale Di Lugano A composition based on natural extracts useful in the prevention and treatment of cutaneous wrinkles
WO2002087700A1 (en) * 2001-04-26 2002-11-07 The Procter & Gamble Company Method, kit and device for the treatment of cosmetic skin conditions
ITMI20011182A1 (it) * 2001-06-05 2002-12-05 Indena Spa Composizioni farmaceutiche e/o cosmetiche per il trattamento di adiposita' localizzate e della cellulite

Also Published As

Publication number Publication date
RU2358726C2 (ru) 2009-06-20
SI1658064T1 (sl) 2010-04-30
US7976881B2 (en) 2011-07-12
BRPI0412365B1 (pt) 2016-11-22
ES2621505T3 (es) 2017-07-04
WO2005004858A1 (en) 2005-01-20
EP1658064B1 (en) 2010-01-20
ITMI20031427A1 (it) 2005-01-12
JP2009513519A (ja) 2009-04-02
RU2006100308A (ru) 2006-06-10
EP2158909A1 (en) 2010-03-03
ES2335995T3 (es) 2010-04-07
PL1658064T3 (pl) 2010-06-30
NO20060152L (no) 2006-01-10
CN1819826A (zh) 2006-08-16
CA2532828C (en) 2017-05-30
NO335285B1 (no) 2014-11-03
DK2158909T3 (en) 2017-06-12
HUE032952T2 (en) 2017-11-28
AU2004255442A1 (en) 2005-01-20
WO2005004858A8 (en) 2005-03-10
EP1658064A2 (en) 2006-05-24
SI2158909T1 (sl) 2017-05-31
DK1658064T3 (da) 2010-05-10
CA2532828A1 (en) 2005-01-20
RU2481852C2 (ru) 2013-05-20
ATE455544T1 (de) 2010-02-15
PT2158909T (pt) 2017-04-11
KR20120036373A (ko) 2012-04-17
JP4964590B2 (ja) 2012-07-04
EP2158909B1 (en) 2017-03-22
PT1658064E (pt) 2010-03-10
KR20060040669A (ko) 2006-05-10
DE602004025253D1 (de) 2010-03-11
KR101166935B1 (ko) 2012-07-27
US20070020349A1 (en) 2007-01-25
RU2009101337A (ru) 2010-07-27
AU2004255442B2 (en) 2010-04-08
KR101227788B1 (ko) 2013-01-29
PL2158909T3 (pl) 2017-09-29
BRPI0412365B8 (pt) 2021-05-25

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 31/37 , A61K 35/78 , A61K 31/70 , A61K 31/7048 , A61K 8/97 , A61Q 19/06 , A61P 17/00

Ipc: A61K 31/37 (2006.01), A61K 35/78 (2006.01), A61K 3

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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Ipc: A61Q 19/06 (2006.01), A61K 8/97 (2017.01), A61K 31

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/07/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF