JP2009512663A5 - - Google Patents

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Publication number
JP2009512663A5
JP2009512663A5 JP2008536060A JP2008536060A JP2009512663A5 JP 2009512663 A5 JP2009512663 A5 JP 2009512663A5 JP 2008536060 A JP2008536060 A JP 2008536060A JP 2008536060 A JP2008536060 A JP 2008536060A JP 2009512663 A5 JP2009512663 A5 JP 2009512663A5
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JP
Japan
Prior art keywords
powder
medicament
surfactant
pharmaceutical composition
inhalation
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Application number
JP2008536060A
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English (en)
Japanese (ja)
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JP5873616B2 (ja
JP2009512663A (ja
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Publication date
Priority claimed from ITMI20051999 external-priority patent/ITMI20051999A1/it
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Publication of JP2009512663A5 publication Critical patent/JP2009512663A5/ja
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Publication of JP5873616B2 publication Critical patent/JP5873616B2/ja
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JP2008536060A 2005-10-21 2006-10-20 乾燥粉末、またはそれから得られた溶液もしくは懸濁液の形態にある吸入用医薬組成物およびその製造方法 Active JP5873616B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2005A001999 2005-10-21
ITMI20051999 ITMI20051999A1 (it) 2005-10-21 2005-10-21 Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
PCT/EP2006/067619 WO2007045689A2 (en) 2005-10-21 2006-10-20 Inhalatory pharmaceutical compositions in form of dry powders, solutions or suspensions

Publications (3)

Publication Number Publication Date
JP2009512663A JP2009512663A (ja) 2009-03-26
JP2009512663A5 true JP2009512663A5 (enExample) 2009-11-26
JP5873616B2 JP5873616B2 (ja) 2016-03-01

Family

ID=37806135

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008536060A Active JP5873616B2 (ja) 2005-10-21 2006-10-20 乾燥粉末、またはそれから得られた溶液もしくは懸濁液の形態にある吸入用医薬組成物およびその製造方法

Country Status (13)

Country Link
US (1) US9138407B2 (enExample)
EP (1) EP1937229B1 (enExample)
JP (1) JP5873616B2 (enExample)
CY (1) CY1116503T1 (enExample)
DK (1) DK1937229T3 (enExample)
ES (1) ES2537777T3 (enExample)
HU (1) HUE026045T2 (enExample)
IT (1) ITMI20051999A1 (enExample)
PL (1) PL1937229T3 (enExample)
PT (1) PT1937229E (enExample)
RU (1) RU2497507C2 (enExample)
SI (1) SI1937229T1 (enExample)
WO (1) WO2007045689A2 (enExample)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
WO2007083073A1 (en) 2006-01-19 2007-07-26 Optinose As Nasal administration
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
US8614236B2 (en) * 2006-12-12 2013-12-24 University Of Washington Methods of treating pulmonary disease using acetazolamide and structurally related derivatives
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
DK3354276T3 (da) 2007-11-13 2020-03-30 Meritage Pharma Inc Sammensætninger til behandlingen af gastrointestinal inflammation
US20090131386A1 (en) * 2007-11-13 2009-05-21 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
DK2230934T3 (da) 2007-12-14 2012-11-26 Aerodesigns Inc Afgivelse af aerosoliserbare næringsmiddelprodukter
JP5485879B2 (ja) * 2008-05-15 2014-05-07 株式会社ココカラファインネクスト 異なる物性の薬物の一剤形化
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
DK2413902T3 (da) * 2009-03-18 2019-10-07 Incarda Therapeutics Inc Enhedsdoser, aerosoler, kits og fremgangsmåder til behandling af hjertetilstande ved pulmonal indgivelse
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
RU2445119C2 (ru) * 2010-05-25 2012-03-20 Сергей Викторович Чепур Фармацевтическая композиция и способ ее ингаляционного введения
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
JP5877204B2 (ja) 2010-09-29 2016-03-02 パルマトリックス,インコーポレイテッド 吸入用の一価金属カチオン乾燥粉末
GB2488992A (en) * 2011-03-10 2012-09-19 Advanced Ophthalmic Pharma Ltd Medicament dispenser
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
DK2704724T3 (en) * 2011-05-03 2017-01-09 Chiesi Farm Spa Improved suspension formulation of beclomethasone dipropionate for administration by inhalation
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
JP6197515B2 (ja) * 2012-10-19 2017-09-20 大正製薬株式会社 医薬組成物
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
US9757395B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
AU2014249529B2 (en) * 2013-03-13 2018-08-09 Actavis Group Ptc Ehf Micronized pharmaceutical compositions
US9452139B2 (en) 2013-03-14 2016-09-27 Novartis Ag Respirable agglomerates of porous carrier particles and micronized drug
KR102246914B1 (ko) 2013-03-15 2021-04-30 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
US11554229B2 (en) 2013-03-26 2023-01-17 OptiNose Inc. Nasal administration
ITMI20130571A1 (it) * 2013-04-10 2014-10-11 Zambon Spa Composizione farmaceutica contenente budesonide e formoterolo
ITMI20130572A1 (it) * 2013-04-10 2014-10-11 Eratech Srl Composizione comprendente almeno due polveri secche ottenute per spray dry per aumentare la stabilita' della formulazione
CA2910766C (en) 2013-04-30 2020-12-15 Otitopic Inc. Dry powder formulations and methods of use
CN104274426A (zh) 2013-07-03 2015-01-14 陆克塞纳医药公司 昂丹司琼细粉、昂丹司琼气溶胶组合物及其用途
WO2016004409A1 (en) * 2014-07-03 2016-01-07 Luxena Pharmaceuticals, Inc. Novel aerosol formulations of ondansetron and uses thereof
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
RU2539374C1 (ru) * 2013-11-29 2015-01-20 Федеральное государственное автономное образовательное учреждение высшего образования "Новосибирский национальный исследовательский государственный университет" (Новосибирский государственный университет, НГУ) Высокодисперсная комбинированная фармацевтическая композиция беклометазона и сальбутамола с бета-глицином и способ ее получения
GB201321712D0 (en) * 2013-12-09 2014-01-22 Pharmachemie Bv Dry Powder Inhaler
CN112656780A (zh) 2014-02-20 2021-04-16 奥迪托皮克股份有限公司 用于吸入的干粉制剂
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
WO2015187356A1 (en) * 2014-06-04 2015-12-10 Quick Joshua Ryan System and method for delivering an inhalable sugar formulation
HUE055527T2 (hu) 2014-09-15 2021-12-28 Verona Pharma Plc RPL554-t tartalmazó folyékony inhalációs készítmény
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN107205958A (zh) * 2014-10-08 2017-09-26 萨宝公司 包含福莫特罗和布地奈德的药物组合物
JP6919093B2 (ja) * 2014-10-08 2021-08-18 ザンボン ソシエタ ペル アチオニ 配合物の安定性を高めるために噴霧乾燥によって得られる少なくとも1種の乾燥粉末を含む組成物
CA2965759C (en) 2014-10-31 2023-12-12 Glaxosmithkline Intellectual Property Development Limited Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials
WO2017022814A1 (ja) * 2015-08-05 2017-02-09 第一三共株式会社 ネブライザー用組成物
RU2731212C2 (ru) * 2015-09-09 2020-08-31 Новартис Аг Направленная доставка высушенных распылением композиций в легкие
ES2898425T3 (es) * 2015-10-20 2022-03-07 Braun Melsungen Ag Composición acuosa que comprende dantroleno
SG10202012584UA (en) 2016-02-01 2021-01-28 Incarda Therapeutics Inc Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation
EP3478265B1 (en) * 2016-06-30 2025-01-01 Philip Morris Products S.A. Nicotine particles
RU2767064C2 (ru) * 2016-06-30 2022-03-16 Филип Моррис Продактс С.А. Никотиносодержащие частицы и композиции
RU2766086C2 (ru) 2016-10-14 2022-02-07 Пулматрикс Оперэйтинг Компани, Инк. Противогрибковые сухие порошки
CN110300588A (zh) * 2017-03-07 2019-10-01 菲利普莫里斯生产公司 可吸入尼古丁调配物及其制造和使用方法
CA3060702A1 (en) 2017-05-10 2018-11-15 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
WO2019036483A1 (en) * 2017-08-15 2019-02-21 Nephron Pharmaceuticals Corporation AQUEOUS NEBULIZATION COMPOSITION
US10786456B2 (en) 2017-09-22 2020-09-29 Otitopic Inc. Inhaled aspirin and magnesium to treat inflammation
CA3076353A1 (en) 2017-09-22 2019-03-28 Otitopic Inc. Dry powder compositions with magnesium stearate
AU2019205329B2 (en) 2018-01-05 2023-04-20 Impel Pharmaceuticals Inc. Intranasal delivery of olanzapine by precision olfactory device
EP3768378B1 (en) 2018-03-22 2025-08-06 InCarda Therapeutics, Inc. A novel method to slow ventricular rate
WO2020150460A1 (en) * 2019-01-18 2020-07-23 Milne Iii Donald A Micronized aspirin formulation
US11020384B2 (en) 2019-08-01 2021-06-01 Incarda Therapeutics, Inc. Antiarrhythmic formulation
IL290088B2 (en) 2019-08-01 2023-10-01 Incarda Therapeutics Inc A pharmaceutical preparation containing flacainide, cyclodextrin and acid, a dosage unit of the preparation and a kit containing the preparation
RU2730488C1 (ru) * 2019-08-20 2020-08-24 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт биомедицинской химии имени В.Н. Ореховича" (ИБМХ) Фармацевтическая композиция на основе глюкокортикостероида будесонида и фосфатидилхолина для сухой ингаляции
GB201914532D0 (en) * 2019-10-08 2019-11-20 Univ Of Huddersfield Lactose particles and method of production thereof
RU2735502C1 (ru) * 2020-01-09 2020-11-03 Федеральное государственное бюджетное учреждение науки Удмуртский федеральный исследовательский центр Уральского отделения Российской академии наук Аэрозоль для ингаляций при обструктивном бронхите
CN111202723A (zh) * 2020-02-15 2020-05-29 江苏艾立康药业股份有限公司 一种达芦那韦吸入干粉药物组合物及其制备方法
US20230270754A1 (en) * 2020-07-31 2023-08-31 Chemo Research, S.L. Combination therapy for inhalation administration
US20250108068A1 (en) * 2023-09-28 2025-04-03 Color Ventures LLC Compositions and methods for alleviating pulmonary ailments

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3009598B2 (ja) 1994-02-18 2000-02-14 武田薬品工業株式会社 プレフィルドシリンジ
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
ATE239447T1 (de) * 1997-09-29 2003-05-15 Inhale Therapeutic Syst In verneblern verwendbare, stabilisierte zubereitungen
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
CA2336139C (en) 1998-06-24 2008-10-14 Advanced Inhalation Research, Inc. Large porous particles emitted from an inhaler
CA2382821A1 (en) 1999-08-25 2001-03-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
CN1188111C (zh) 1999-10-29 2005-02-09 耐科塔医药公司 分散性得到改进的干粉组合物
GB9929486D0 (en) 1999-12-15 2000-02-09 Glaxo Group Ltd Inhalation delivery apparatus and method
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
CA2413692C (en) 2000-06-27 2011-10-18 Vectura Limited Method of making particles for use in a pharmaceutical composition
IL153705A0 (en) 2000-06-27 2003-07-06 Vectura Ltd Method of making particles for use in a pharmaceutical composition
US20020103139A1 (en) 2000-12-01 2002-08-01 M. Weisspapir Solid self-emulsifying controlled release drug delivery system composition for enhanced delivery of water insoluble phytosterols and other hydrophobic natural compounds for body weight and cholestrol level control
US20110123574A1 (en) * 2002-03-20 2011-05-26 Alkermes, Inc. Inhalable sustained therapeutic formulations
AU2003230689B2 (en) 2002-03-20 2006-06-29 Alkermes, Inc. Inhalable sustained therapeutic formulations
EP1531794B1 (en) 2002-06-28 2017-05-10 Civitas Therapeutics, Inc. Inhalable epinephrine
CA2500065A1 (en) 2002-09-30 2004-04-15 Acusphere, Inc. Sustained release porous microparticles for inhalation
EP1589947B2 (en) * 2002-12-31 2019-01-30 Novartis AG Pharmaceutical formulation with an insoluble active agent for pulmonary administration
EP1617820B1 (en) 2003-04-14 2018-03-21 Vectura Limited Dry power inhaler devices and dry power formulations for enhancing dosing efficiency
US20060292081A1 (en) 2003-09-15 2006-12-28 Vectura Limited Methods for preparing pharmaceutical compositions
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070043030A1 (en) 2003-09-15 2007-02-22 Vectura Limited Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
ITMI20040795A1 (it) * 2004-04-23 2004-07-23 Eratech S R L Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa

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