JP2013541565A5 - - Google Patents
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- Publication number
- JP2013541565A5 JP2013541565A5 JP2013537018A JP2013537018A JP2013541565A5 JP 2013541565 A5 JP2013541565 A5 JP 2013541565A5 JP 2013537018 A JP2013537018 A JP 2013537018A JP 2013537018 A JP2013537018 A JP 2013537018A JP 2013541565 A5 JP2013541565 A5 JP 2013541565A5
- Authority
- JP
- Japan
- Prior art keywords
- nasal
- administered
- nose
- pharmaceutical formulations
- formulations adapted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001331 nose Anatomy 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 241000792859 Enema Species 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 239000007920 enema Substances 0.000 description 1
- 229940079360 enema for constipation Drugs 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 239000007923 nasal drop Substances 0.000 description 1
- 229940100662 nasal drops Drugs 0.000 description 1
- 239000007922 nasal spray Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010050558.7 | 2010-11-05 | ||
| DE102010050558A DE102010050558A1 (de) | 2010-11-05 | 2010-11-05 | 1H-Pyrrolo[2,3-b]pyridinderivate |
| PCT/EP2011/005127 WO2012059172A1 (de) | 2010-11-05 | 2011-10-12 | 1h-pyrrolo[2,3-b]pyridinderivate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013541565A JP2013541565A (ja) | 2013-11-14 |
| JP2013541565A5 true JP2013541565A5 (enExample) | 2016-01-28 |
| JP5891234B2 JP5891234B2 (ja) | 2016-03-22 |
Family
ID=44897681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537018A Expired - Fee Related JP5891234B2 (ja) | 2010-11-05 | 2011-10-12 | １ｈ−ピロロ［２，３−ｂ］ピリジン誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8664236B2 (enExample) |
| EP (1) | EP2635574B1 (enExample) |
| JP (1) | JP5891234B2 (enExample) |
| CN (1) | CN103180320B (enExample) |
| AR (1) | AR083751A1 (enExample) |
| AU (1) | AU2011325480B2 (enExample) |
| CA (1) | CA2816896C (enExample) |
| DE (1) | DE102010050558A1 (enExample) |
| ES (1) | ES2525172T3 (enExample) |
| IL (1) | IL226095A (enExample) |
| WO (1) | WO2012059172A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010050558A1 (de) * | 2010-11-05 | 2012-05-10 | Merck Patent Gmbh | 1H-Pyrrolo[2,3-b]pyridinderivate |
| DE102010053347A1 (de) * | 2010-12-03 | 2012-06-06 | Merck Patent Gmbh | 3-Hetaryl-substituierte Pyrrolo[2,3-b] pyridin-derivative als PDK1-Inhibitoren |
| AU2013263420A1 (en) * | 2012-05-15 | 2015-01-22 | Calasia Pharmaceuticals, Inc. | Pyrimidine diamine derivatives as inhibitors of cytosolic Hsp90 |
| EP2738172A1 (en) * | 2012-11-28 | 2014-06-04 | Almirall, S.A. | New bicyclic compounds as crac channel modulators |
| SG11201700777VA (en) | 2014-08-04 | 2017-02-27 | Nuevolution As | Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases |
| WO2017184549A1 (en) * | 2016-04-18 | 2017-10-26 | Innov17 Llc | Pyrrolopyridine retinoic acid receptor-related orphan receptor modulators and uses thereof |
| US11447479B2 (en) | 2019-12-20 | 2022-09-20 | Nuevolution A/S | Compounds active towards nuclear receptors |
| TWI872177B (zh) | 2019-12-20 | 2025-02-11 | 丹麥商紐韋盧森公司 | 對核受體具有活性之化合物 |
| JP7713953B2 (ja) | 2020-03-31 | 2025-07-28 | ヌエヴォリューション・アクティーゼルスカブ | 核内受容体に対して活性な化合物 |
| CA3174176A1 (en) | 2020-03-31 | 2021-10-07 | Sanne Schroder Glad | Compounds active towards nuclear receptors |
| EP4294513A1 (en) | 2021-02-19 | 2023-12-27 | Mevion Medical Systems, Inc. | Gantry for a particle therapy system |
| WO2022203399A1 (ko) * | 2021-03-26 | 2022-09-29 | 주식회사 스탠다임 | 아데노신 a2a 수용체 길항제 및 이의 용도 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5747469A (en) | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
| GB9904387D0 (en) | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
| GB0308466D0 (en) | 2003-04-11 | 2003-05-21 | Novartis Ag | Organic compounds |
| DE102006012617A1 (de) * | 2006-03-20 | 2007-09-27 | Merck Patent Gmbh | 4-(Pyrrolopyridinyl)-pyrimidinyl-2-amin-derivate |
| US20100267707A1 (en) * | 2006-06-22 | 2010-10-21 | Merck Sharp & Dohme Corp. | Tyrosine Kinase Inhibitors |
| DE102007028515A1 (de) | 2007-06-21 | 2008-12-24 | Merck Patent Gmbh | 6-(Pyrrolopyridinyl)-pyrimidinyl-2-amin-derivate |
| DE102008031517A1 (de) * | 2008-07-03 | 2010-01-07 | Merck Patent Gmbh | Pyrrolopyridinyl-pyrimidin-2-yl-amin-derivate |
| TW201016676A (en) * | 2008-10-03 | 2010-05-01 | Astrazeneca Ab | Heterocyclic derivatives and methods of use thereof |
| DE102008052943A1 (de) * | 2008-10-23 | 2010-04-29 | Merck Patent Gmbh | Azaindolderivate |
| DE102009060174A1 (de) * | 2009-12-23 | 2011-06-30 | Merck Patent GmbH, 64293 | Pyrrolopyridinyl-pyrimidin-2-yl-amin-derivate |
| DE102010050558A1 (de) * | 2010-11-05 | 2012-05-10 | Merck Patent Gmbh | 1H-Pyrrolo[2,3-b]pyridinderivate |
-
2010
- 2010-11-05 DE DE102010050558A patent/DE102010050558A1/de not_active Withdrawn
-
2011
- 2011-10-12 JP JP2013537018A patent/JP5891234B2/ja not_active Expired - Fee Related
- 2011-10-12 WO PCT/EP2011/005127 patent/WO2012059172A1/de not_active Ceased
- 2011-10-12 EP EP11773397.2A patent/EP2635574B1/de not_active Not-in-force
- 2011-10-12 US US13/883,411 patent/US8664236B2/en not_active Expired - Fee Related
- 2011-10-12 CA CA2816896A patent/CA2816896C/en not_active Expired - Fee Related
- 2011-10-12 AU AU2011325480A patent/AU2011325480B2/en not_active Ceased
- 2011-10-12 CN CN201180053259.7A patent/CN103180320B/zh not_active Expired - Fee Related
- 2011-10-12 ES ES11773397.2T patent/ES2525172T3/es active Active
- 2011-11-04 AR ARP110104105A patent/AR083751A1/es not_active Application Discontinuation
-
2013
- 2013-05-01 IL IL226095A patent/IL226095A/en not_active IP Right Cessation
- 2013-10-02 US US14/044,330 patent/US8895575B2/en not_active Expired - Fee Related
-
2014
- 2014-08-13 US US14/458,759 patent/US9238651B2/en not_active Expired - Fee Related
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