JP2008521861A5 - - Google Patents

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Publication number
JP2008521861A5
JP2008521861A5 JP2007543838A JP2007543838A JP2008521861A5 JP 2008521861 A5 JP2008521861 A5 JP 2008521861A5 JP 2007543838 A JP2007543838 A JP 2007543838A JP 2007543838 A JP2007543838 A JP 2007543838A JP 2008521861 A5 JP2008521861 A5 JP 2008521861A5
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JP
Japan
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compound
formula
group
alkyl
hydrogen
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JP2007543838A
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English (en)
Japanese (ja)
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JP5164574B2 (ja
JP2008521861A (ja
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Priority claimed from DE102004058337A external-priority patent/DE102004058337A1/de
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Publication of JP5164574B2 publication Critical patent/JP5164574B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007543838A 2004-12-02 2005-11-29 環付加ピペラジン−2−オン誘導体の製造方法及び前記方法の中間体 Expired - Lifetime JP5164574B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004058337A DE102004058337A1 (de) 2004-12-02 2004-12-02 Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
DE102004058337.4 2004-12-02
PCT/EP2005/056291 WO2006058876A1 (de) 2004-12-02 2005-11-29 Verfahren zur herstellung von annelierten piperazin-2-on derivaten sowie zwischenprodukte des verfahrens

Publications (3)

Publication Number Publication Date
JP2008521861A JP2008521861A (ja) 2008-06-26
JP2008521861A5 true JP2008521861A5 (https=) 2009-01-22
JP5164574B2 JP5164574B2 (ja) 2013-03-21

Family

ID=35923724

Family Applications (1)

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JP2007543838A Expired - Lifetime JP5164574B2 (ja) 2004-12-02 2005-11-29 環付加ピペラジン−2−オン誘導体の製造方法及び前記方法の中間体

Country Status (34)

Country Link
US (9) US7238807B2 (https=)
EP (2) EP1819706B1 (https=)
JP (1) JP5164574B2 (https=)
KR (2) KR101395591B1 (https=)
CN (3) CN101065381B (https=)
AR (1) AR053100A1 (https=)
AU (1) AU2005311308B2 (https=)
BR (1) BRPI0518601A2 (https=)
CA (1) CA2588857C (https=)
CL (1) CL2013002895A1 (https=)
CY (1) CY1113625T1 (https=)
DE (1) DE102004058337A1 (https=)
DK (2) DK1819706T3 (https=)
EA (1) EA012624B1 (https=)
ES (2) ES2548680T3 (https=)
HR (1) HRP20120980T1 (https=)
HU (1) HUE027689T2 (https=)
IL (1) IL183568A (https=)
ME (1) ME01470B (https=)
MX (1) MX2007006549A (https=)
MY (1) MY147459A (https=)
NO (1) NO20072283L (https=)
NZ (1) NZ556182A (https=)
PE (2) PE20061061A1 (https=)
PL (2) PL2436685T3 (https=)
PT (1) PT1819706E (https=)
RS (1) RS52533B (https=)
SG (2) SG158848A1 (https=)
SI (1) SI1819706T1 (https=)
TW (1) TWI362391B (https=)
UA (1) UA89390C2 (https=)
UY (1) UY29233A1 (https=)
WO (1) WO2006058876A1 (https=)
ZA (1) ZA200703368B (https=)

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CN102020643A (zh) 2009-09-22 2011-04-20 上海恒瑞医药有限公司 二氢喋啶酮类衍生物、其制备方法及其在医药上的应用
CA2773827A1 (en) 2009-09-25 2011-03-31 Vertex Pharmaceuticals Incorporated Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
SG179206A1 (en) 2009-09-25 2012-04-27 Vertex Pharma Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
CA2827770A1 (en) 2011-02-25 2012-11-01 Takeda Pharmaceutical Company Limited N-substituted oxazinopteridines and oxazinopteridinones
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
TW201414734A (zh) 2012-07-10 2014-04-16 Takeda Pharmaceutical 氮雜吲哚衍生物
US20150031699A1 (en) 2013-07-26 2015-01-29 Boehringer Ingelheim International Gmbh Treatment of myelodysplastic syndrome
AR099052A1 (es) 2014-01-09 2016-06-29 Takeda Pharmaceuticals Co Derivados de azaindol
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

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EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
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EP2185559A1 (en) 2007-08-03 2010-05-19 Boehringer Ingelheim International GmbH Crystalline form of a dihydropteridione derivative

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