ME01470B - Postupak za dobijanje anelacijskih piperazin-2-on derivata i intermedijera navedenog postupka - Google Patents

Postupak za dobijanje anelacijskih piperazin-2-on derivata i intermedijera navedenog postupka

Info

Publication number
ME01470B
ME01470B MEP-2012-124A MEP12412A ME01470B ME 01470 B ME01470 B ME 01470B ME P12412 A MEP12412 A ME P12412A ME 01470 B ME01470 B ME 01470B
Authority
ME
Montenegro
Prior art keywords
piperayin
annelated
intermediates
derivatives
producing
Prior art date
Application number
MEP-2012-124A
Other languages
English (en)
Unknown language (me)
Inventor
Guenter Linz
Adil Duran
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35923724&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME01470(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ME01470B publication Critical patent/ME01470B/me

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MEP-2012-124A 2004-12-02 2005-11-29 Postupak za dobijanje anelacijskih piperazin-2-on derivata i intermedijera navedenog postupka ME01470B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004058337A DE102004058337A1 (de) 2004-12-02 2004-12-02 Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
PCT/EP2005/056291 WO2006058876A1 (de) 2004-12-02 2005-11-29 Verfahren zur herstellung von annelierten piperazin-2-on derivaten sowie zwischenprodukte des verfahrens
EP05823799A EP1819706B1 (de) 2004-12-02 2005-11-29 Verfahren zur herstellung von annelierten piperazin-2-on derivaten sowie zwischenprodukte des verfahrens

Publications (1)

Publication Number Publication Date
ME01470B true ME01470B (me) 2014-04-20

Family

ID=35923724

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2012-124A ME01470B (me) 2004-12-02 2005-11-29 Postupak za dobijanje anelacijskih piperazin-2-on derivata i intermedijera navedenog postupka

Country Status (34)

Country Link
US (9) US7238807B2 (https=)
EP (2) EP1819706B1 (https=)
JP (1) JP5164574B2 (https=)
KR (2) KR101395591B1 (https=)
CN (3) CN101065381B (https=)
AR (1) AR053100A1 (https=)
AU (1) AU2005311308B2 (https=)
BR (1) BRPI0518601A2 (https=)
CA (1) CA2588857C (https=)
CL (1) CL2013002895A1 (https=)
CY (1) CY1113625T1 (https=)
DE (1) DE102004058337A1 (https=)
DK (2) DK1819706T3 (https=)
EA (1) EA012624B1 (https=)
ES (2) ES2548680T3 (https=)
HR (1) HRP20120980T1 (https=)
HU (1) HUE027689T2 (https=)
IL (1) IL183568A (https=)
ME (1) ME01470B (https=)
MX (1) MX2007006549A (https=)
MY (1) MY147459A (https=)
NO (1) NO20072283L (https=)
NZ (1) NZ556182A (https=)
PE (2) PE20061061A1 (https=)
PL (2) PL2436685T3 (https=)
PT (1) PT1819706E (https=)
RS (1) RS52533B (https=)
SG (2) SG158848A1 (https=)
SI (1) SI1819706T1 (https=)
TW (1) TWI362391B (https=)
UA (1) UA89390C2 (https=)
UY (1) UY29233A1 (https=)
WO (1) WO2006058876A1 (https=)
ZA (1) ZA200703368B (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861422B2 (en) * 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
DE102004029784A1 (de) * 2004-06-21 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004033670A1 (de) * 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US20060035903A1 (en) * 2004-08-14 2006-02-16 Boehringer Ingelheim International Gmbh Storage stable perfusion solution for dihydropteridinones
US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
US20060074088A1 (en) * 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
US7728134B2 (en) * 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US7759485B2 (en) * 2004-08-14 2010-07-20 Boehringer Ingelheim International Gmbh Process for the manufacture of dihydropteridinones
EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1632493A1 (de) * 2004-08-25 2006-03-08 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004058337A1 (de) * 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
US7439358B2 (en) * 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
TW200804389A (en) 2006-02-14 2008-01-16 Vertex Pharma Dihydrodiazepines useful as inhibitors of protein kinases
JP4958461B2 (ja) * 2006-03-30 2012-06-20 富士フイルム株式会社 近赤外吸収色素含有硬化性組成物
MX2009008084A (es) 2007-02-01 2009-10-12 Astrazeneca Ab Derivados de 5,6,7,8-tetrahidropteridina como inhibidores de hsp90.
EP2185559A1 (en) * 2007-08-03 2010-05-19 Boehringer Ingelheim International GmbH Crystalline form of a dihydropteridione derivative
EP2100894A1 (en) 2008-03-12 2009-09-16 4Sc Ag Pyridopyrimidines used as Plk1 (polo-like kinase) inhibitors
CN102020643A (zh) 2009-09-22 2011-04-20 上海恒瑞医药有限公司 二氢喋啶酮类衍生物、其制备方法及其在医药上的应用
CA2773827A1 (en) 2009-09-25 2011-03-31 Vertex Pharmaceuticals Incorporated Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
SG179206A1 (en) 2009-09-25 2012-04-27 Vertex Pharma Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
CA2827770A1 (en) 2011-02-25 2012-11-01 Takeda Pharmaceutical Company Limited N-substituted oxazinopteridines and oxazinopteridinones
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
TW201414734A (zh) 2012-07-10 2014-04-16 Takeda Pharmaceutical 氮雜吲哚衍生物
US20150031699A1 (en) 2013-07-26 2015-01-29 Boehringer Ingelheim International Gmbh Treatment of myelodysplastic syndrome
AR099052A1 (es) 2014-01-09 2016-06-29 Takeda Pharmaceuticals Co Derivados de azaindol
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032639A (en) * 1976-03-22 1977-06-28 American Home Products Corporation 2,3,4,4A-Tetrahydro-1H-pyrazino[1,2-a,]quinoxalin-5(6H)-ones and derivatives thereof for relieving hypertension
US4182872A (en) * 1976-03-22 1980-01-08 American Home Products Corporation 4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid chemical intermediates
NL8303657A (nl) 1983-10-24 1985-05-17 Pharmachemie Bv Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
DE68908786T2 (de) 1988-06-16 1994-03-17 Smith Kline French Lab Condensierte Pyrimidinderivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.
FR2645152B1 (fr) 1989-03-30 1991-05-31 Lipha 3h-pteridinones-4, procedes de preparation et medicaments les contenant
US5043270A (en) 1989-03-31 1991-08-27 The Board Of Trustees Of The Leland Stanford Junior University Intronic overexpression vectors
CA2029651C (en) 1989-11-17 2000-06-06 David D. Davey Tricyclic pteridinones and a process for their preparation
US5198547A (en) 1992-03-16 1993-03-30 South Alabama Medical Science Foundation, Usa Process for N5-formylating tetrahydropteridines
TW274550B (https=) * 1992-09-26 1996-04-21 Hoechst Ag
EP1195372A1 (en) 1994-04-18 2002-04-10 Mitsubishi Pharma Corporation N-heterocyclic substituted benzamide derivatives with antihypertensive activity
CO4410191A1 (es) 1994-09-19 1997-01-09 Lilly Co Eli SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
ES2154825T3 (es) * 1995-05-19 2001-04-16 Novartis Ag Procedimiento para la hidrogenacion catalitica de nitro compuestos aromaticos.
US5698556A (en) * 1995-06-07 1997-12-16 Chan; Carcy L. Methotrexate analogs and methods of using same
CZ299247B6 (cs) 1996-09-23 2008-05-28 Eli Lilly And Company Olanzapin dihydrát D
JP2002522541A (ja) * 1998-08-11 2002-07-23 ファイザー・プロダクツ・インク ホスホジエステラーゼ４阻害剤としての置換１，８−ナフチリジン−４（１ｈ）−オン
EP1409487A1 (en) * 1999-09-15 2004-04-21 Warner-Lambert Company Llc Pteridinones as kinase inhibitors
GB2359551A (en) 2000-02-23 2001-08-29 Astrazeneca Uk Ltd Pharmaceutically active pyrimidine derivatives
PL358271A1 (pl) 2000-03-06 2004-08-09 Warner-Lambert Company 5-alkilopirydo[2,3-D]pirymidyny jako inhibitory kinazy tyrozyny
DE10018783A1 (de) 2000-04-15 2001-10-25 Fresenius Kabi De Gmbh Lagerstabile Infusionslösung des Ciprofloxacins mit verringertem Säuregehalt
US20020183292A1 (en) * 2000-10-31 2002-12-05 Michel Pairet Pharmaceutical compositions based on anticholinergics and corticosteroids
DE10058119A1 (de) * 2000-11-22 2002-05-23 Bayer Ag Pepinotan-Kit
US6756374B2 (en) 2001-01-22 2004-06-29 Hoffmann-La Roche Inc. Diaminothiazoles having antiproliferative activity
WO2002076954A1 (en) 2001-03-23 2002-10-03 Smithkline Beecham Corporation Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases
WO2002076985A1 (en) 2001-03-23 2002-10-03 Smithkline Beecham Corporation Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6806272B2 (en) * 2001-09-04 2004-10-19 Boehringer Ingelheim Pharma Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
PT1427730E (pt) 2001-09-04 2006-11-30 Boehringer Ingelheim Pharma Novas di-hidropteridinonas, processo para sua preparação e sua utilização como medicamento
PT1463493E (pt) * 2001-12-14 2008-01-04 Serono Lab Método para induzir a ovulação utilizando um modulador de nível camp não polipeptídico
JP2005538048A (ja) 2002-05-03 2005-12-15 シエーリング アクチエンゲゼルシャフト チアゾリジノン類、それらの生成及び医薬剤としての使用
MXPA05001544A (es) 2002-08-08 2005-04-19 Smithkline Beecham Corp Compuestos de tiofeno.
US6862422B2 (en) * 2003-02-12 2005-03-01 Kabushiki Kaisha Toshiba Image forming apparatus and image forming method having pressing members for pressing a belt-like member
US6861422B2 (en) * 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
BR0318145A (pt) 2003-02-26 2006-02-21 Boehringer Ingelheim Pharma dihidropteridinonas, processos para a sua preparação e sua aplicação como medicamento
US20040180898A1 (en) * 2003-03-03 2004-09-16 Bang-Chi Chen Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines
US20070134200A1 (en) 2003-03-26 2007-06-14 Wyeth Immunogenic composition and methods
JP2006522634A (ja) 2003-04-14 2006-10-05 ベクトゥラ・リミテッド 投与効率を向上させるデバイス及び製薬組成
JP2007517828A (ja) 2004-01-17 2007-07-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 気道の疾患を治療するための置換プテリジンの使用
DE102004002557A1 (de) * 2004-01-17 2005-08-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von substituierten Pyrimido(5,4-d)pyrimidinen zur Behandlung von Atemwegserkrankungen
DE102004029784A1 (de) * 2004-06-21 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004033670A1 (de) * 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
DE102004034623A1 (de) * 2004-07-16 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 6-Formyl-tetrahydropteridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7759485B2 (en) 2004-08-14 2010-07-20 Boehringer Ingelheim International Gmbh Process for the manufacture of dihydropteridinones
US7728134B2 (en) * 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US20060035903A1 (en) 2004-08-14 2006-02-16 Boehringer Ingelheim International Gmbh Storage stable perfusion solution for dihydropteridinones
US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
US20060074088A1 (en) * 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
EP1632493A1 (de) * 2004-08-25 2006-03-08 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
CA2575804A1 (en) * 2004-08-26 2006-03-02 Boehringer Ingelheim International Gmbh Pteridinones used as plk (polo like kinase) inhibitors
JP2008510771A (ja) * 2004-08-27 2008-04-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ジヒドロプテリジノン、その製造方法および医薬薬剤としてのその使用
DE102004058337A1 (de) * 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
WO2007014838A1 (en) 2005-08-03 2007-02-08 Boehringer Ingelheim International Gmbh Dihydropteridinones in the treatment of respiratory diseases
US7439358B2 (en) * 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
JP2009529038A (ja) 2006-03-07 2009-08-13 アストラゼネカ・アクチエボラーグ ピペリジン誘導体、それらの製造法、治療剤としてのそれらの使用およびそれらを含む医薬組成物
EP2185559A1 (en) 2007-08-03 2010-05-19 Boehringer Ingelheim International GmbH Crystalline form of a dihydropteridione derivative

Also Published As

Publication number Publication date
HUE027689T2 (hu) 2021-12-28
UY29233A1 (es) 2006-07-31
US20070213530A1 (en) 2007-09-13
AR053100A1 (es) 2007-04-25
US20070213528A1 (en) 2007-09-13
MY147459A (en) 2012-12-14
PE20061061A1 (es) 2006-11-10
KR20070092252A (ko) 2007-09-12
DK1819706T3 (da) 2013-01-02
EP1819706B1 (de) 2012-09-19
UA89390C2 (ru) 2010-01-25
CN101065381A (zh) 2007-10-31
EP2436685B1 (de) 2015-07-01
CN102093361B (zh) 2014-05-07
TW200628471A (en) 2006-08-16
ES2548680T3 (es) 2015-10-20
CY1113625T1 (el) 2016-06-22
NZ556182A (en) 2009-08-28
CL2013002895A1 (es) 2014-03-14
PL2436685T3 (pl) 2015-11-30
SG141461A1 (en) 2008-04-28
RS52533B (sr) 2013-04-30
AU2005311308A1 (en) 2006-06-08
HK1158200A1 (en) 2012-07-13
USRE43115E1 (en) 2012-01-17
CN102070637B (zh) 2012-09-26
HK1158199A1 (en) 2012-07-13
JP5164574B2 (ja) 2013-03-21
JP2008521861A (ja) 2008-06-26
SG158848A1 (en) 2010-02-26
KR101395591B1 (ko) 2014-05-16
ES2395829T3 (es) 2013-02-15
DE102004058337A1 (de) 2006-06-14
PT1819706E (pt) 2012-12-06
PL1819706T3 (pl) 2013-03-29
EA200701164A1 (ru) 2007-12-28
CA2588857A1 (en) 2006-06-08
US20070213531A1 (en) 2007-09-13
US7238807B2 (en) 2007-07-03
DK2436685T3 (en) 2015-09-14
SI1819706T1 (sl) 2013-01-31
BRPI0518601A2 (pt) 2008-11-25
ZA200703368B (en) 2008-09-25
PE20090488A1 (es) 2009-05-27
EP2436685A1 (de) 2012-04-04
WO2006058876A1 (de) 2006-06-08
CA2588857C (en) 2013-10-08
CN101065381B (zh) 2011-03-30
CN102070637A (zh) 2011-05-25
EA012624B1 (ru) 2009-10-30
US20060122393A1 (en) 2006-06-08
US7626019B2 (en) 2009-12-01
IL183568A (en) 2015-02-26
IL183568A0 (en) 2007-09-20
US20070213529A1 (en) 2007-09-13
US20070219369A1 (en) 2007-09-20
HRP20120980T1 (hr) 2012-12-31
US20070213534A1 (en) 2007-09-13
AU2005311308B2 (en) 2012-04-12
NO20072283L (no) 2007-06-28
TWI362391B (en) 2012-04-21
MX2007006549A (es) 2007-06-18
US20070208027A1 (en) 2007-09-06
KR101362131B1 (ko) 2014-02-19
CN102093361A (zh) 2011-06-15
KR20120136414A (ko) 2012-12-18
HK1113489A1 (en) 2008-10-03
EP1819706A1 (de) 2007-08-22

Similar Documents

Publication Publication Date Title
ME01470B (me) Postupak za dobijanje anelacijskih piperazin-2-on derivata i intermedijera navedenog postupka
IL180742A0 (en) Method of manufacture
GB0704028D0 (en) Method of expansion
IL188898A0 (en) Processes for preparing pyrazol-o-glycoside derivatives and novel intermediates of said processes
GB2464421B (en) Method of forming tubing
EP1764416A4 (en) METHOD OF PRODUCTION OF THEANINE
PL1716141T3 (pl) Pochodne benzopiranu, sposób ich wytwarzania i ich zastosowanie
IL181339A0 (en) Method for the production of diarylcycloalkyl derivatives
IL177649A0 (en) Method of preparing benzazepines and derivatives thereof
PL371171A1 (pl) Nowe pochodne takryny i sposób ich otrzymywania
MD2577F1 (en) Method of abdominal wing peritonization after hemicolectomy
GB2415547B (en) Tubular member and method of production
HU0400586D0 (en) Facing gacaparget and method of producing thereof
PL380363A1 (pl) Nowe pochodne disorbityloaminy i sposób ich otrzymywania
IL179724A0 (en) Method for producing acetamidopyrrolidine derivatives and novel benzamidoacetic acid derivatives as intermediates therefor
PL384045A1 (pl) Sposób wytwarzania olanzapiny
PL371700A1 (pl) Nowe pochodne okta-μ₃-oxododeka-μ-karboksylanocyklohexacyrkonu(IV) oraz sposób ich wytwarzania
HU0401827D0 (en) Method for production of ceramics
PL366960A1 (en) Method for modification of bio-membranes
HU0401136D0 (en) Method for post-blinding of gas-plumbing
PL370547A1 (pl) Sposób wytwarzania poliestroli o budowie rozgałęzionej
PL367920A1 (en) Method for manufacture of oligoetheroles
HU2947U (en) Apparatus for producing of biogas
PL359296A1 (en) New derivative of isoxasol and method for manufacture of new derivative of isoxasol
PL359295A1 (en) New derivative of isoxasol and method for manufacture of new derivative of isoxasol