JP2008521827A5 - - Google Patents
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- Publication number
- JP2008521827A5 JP2008521827A5 JP2007543584A JP2007543584A JP2008521827A5 JP 2008521827 A5 JP2008521827 A5 JP 2008521827A5 JP 2007543584 A JP2007543584 A JP 2007543584A JP 2007543584 A JP2007543584 A JP 2007543584A JP 2008521827 A5 JP2008521827 A5 JP 2008521827A5
- Authority
- JP
- Japan
- Prior art keywords
- agonist
- receptor modulator
- ethyl
- phenyl
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63148304P | 2004-11-29 | 2004-11-29 | |
| PCT/US2005/043044 WO2006058316A1 (en) | 2004-11-29 | 2005-11-28 | Dosage regimen of an s1p receptor agonist |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012040574A Division JP2012107059A (ja) | 2004-11-29 | 2012-02-27 | S1p受容体アゴニストの投与レジメン |
| JP2013043351A Division JP2013129664A (ja) | 2004-11-29 | 2013-03-05 | S1p受容体アゴニストの投与レジメン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008521827A JP2008521827A (ja) | 2008-06-26 |
| JP2008521827A5 true JP2008521827A5 (enExample) | 2009-02-05 |
Family
ID=36046868
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007543584A Withdrawn JP2008521827A (ja) | 2004-11-29 | 2005-11-28 | S1p受容体アゴニストの投与レジメン |
| JP2012040574A Withdrawn JP2012107059A (ja) | 2004-11-29 | 2012-02-27 | S1p受容体アゴニストの投与レジメン |
| JP2013043351A Withdrawn JP2013129664A (ja) | 2004-11-29 | 2013-03-05 | S1p受容体アゴニストの投与レジメン |
| JP2014266267A Pending JP2015061883A (ja) | 2004-11-29 | 2014-12-26 | S1p受容体アゴニストの投与レジメン |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012040574A Withdrawn JP2012107059A (ja) | 2004-11-29 | 2012-02-27 | S1p受容体アゴニストの投与レジメン |
| JP2013043351A Withdrawn JP2013129664A (ja) | 2004-11-29 | 2013-03-05 | S1p受容体アゴニストの投与レジメン |
| JP2014266267A Pending JP2015061883A (ja) | 2004-11-29 | 2014-12-26 | S1p受容体アゴニストの投与レジメン |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US20090275553A1 (enExample) |
| EP (3) | EP1819326B1 (enExample) |
| JP (4) | JP2008521827A (enExample) |
| KR (4) | KR20130041385A (enExample) |
| CN (2) | CN101068536B (enExample) |
| AU (1) | AU2005309378B2 (enExample) |
| BR (1) | BRPI0518674A2 (enExample) |
| CA (1) | CA2589265A1 (enExample) |
| ES (1) | ES2495690T3 (enExample) |
| IL (2) | IL183134A0 (enExample) |
| MA (1) | MA29034B1 (enExample) |
| MX (1) | MX2007006373A (enExample) |
| NO (2) | NO20072401L (enExample) |
| NZ (2) | NZ554720A (enExample) |
| PL (1) | PL1819326T3 (enExample) |
| PT (1) | PT1819326E (enExample) |
| RU (2) | RU2478384C2 (enExample) |
| SG (2) | SG158096A1 (enExample) |
| TN (1) | TNSN07209A1 (enExample) |
| WO (1) | WO2006058316A1 (enExample) |
| ZA (1) | ZA200703328B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2007109207A (ru) | 2004-08-13 | 2008-09-20 | Прикис Фамэсьютикэлс, Инк. (US) | Соединения-модуляторы активности рецептора сфингозин-1-фосфата (варианты), фармацевтическая композиция, содержащая указанные соединения, и способ лечения нарушения, ассоциированного со сфингозин-1-фосфатом |
| CA2589265A1 (en) * | 2004-11-29 | 2006-06-01 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
| PL1926483T3 (pl) * | 2005-09-09 | 2011-05-31 | Novartis Ag | Leczenie chorób autoimmunologicznych |
| GB0612721D0 (en) * | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
| AU2008248648B2 (en) * | 2007-05-04 | 2012-02-23 | Novartis Ag | Use of S1P receptor modulator |
| DK2278960T4 (da) | 2008-03-17 | 2020-01-27 | Actelion Pharmaceuticals Ltd | Dosisregimen til en selektiv sip1 receptoragonist |
| NZ589412A (en) * | 2008-05-20 | 2012-11-30 | Kyorin Seiyaku Kk | Use of a sphingosine-1-phosphate (S1P) agonist for maintance of induced remission of autoimmune or inflammatory diseases after inital treatment |
| AU2009273259B2 (en) * | 2008-07-23 | 2013-05-02 | Novartis Ag | Sphingosine 1 phosphate receptor modulators and their use to treat muscle inflammation |
| WO2010020610A1 (en) * | 2008-08-18 | 2010-02-25 | Novartis Ag | Compounds for the treatment of peripheral neuropathies |
| MX2011006610A (es) | 2008-12-18 | 2011-06-30 | Novartis Ag | Nueva forma polimorfica de acido 1-(4-{l-[(e)-4-ciclohexil-3 -trifluorometil-benciloxi-imino]-etil)-2-etil-bencil)-azetidin-3 carboxilico. |
| ES2478842T3 (es) * | 2008-12-18 | 2014-07-23 | Novartis Ag | Sal clorhidrato del ácido 1-(4-(1-((E)-4-ciclohexil-3-trifluorometil-benziloxiimino)-etil)-2-etil-benzil)-azetidina-3-carboxílico |
| KR20160064245A (ko) * | 2008-12-18 | 2016-06-07 | 노파르티스 아게 | 1-[4-[1-(4-시클로헥실-3-트리플루오로메틸-벤질옥시이미노)-에틸]-2-에틸-벤질]-아제티딘-3-카르복실산의 헤미푸마레이트 염 |
| AR074826A1 (es) * | 2008-12-22 | 2011-02-16 | Novartis Ag | Regimen de dosificacion para un agonista de los receptores de s1p |
| CA2747992C (en) * | 2008-12-22 | 2017-11-07 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
| AU2015275246B2 (en) * | 2008-12-22 | 2018-02-01 | Novartis Ag | Dosage regimen for a S1P receptor agonist |
| AU2010300919A1 (en) | 2009-09-29 | 2012-03-22 | Novartis Ag | Dosage regimen of an S1P receptor modulator |
| US20110124605A1 (en) * | 2009-11-20 | 2011-05-26 | Shreeram Aradhye | Use of an S1P Receptor Agonist |
| US8791100B2 (en) | 2010-02-02 | 2014-07-29 | Novartis Ag | Aryl benzylamine compounds |
| CA2794607A1 (en) * | 2010-05-06 | 2011-11-10 | Novartis Ag | Dosage regimen of diaryl sulfide derivatives |
| PH12013501442B1 (en) | 2011-01-07 | 2018-04-20 | Novartis Ag | Immunosuppressant formulations |
| BR112014009141A8 (pt) * | 2011-10-21 | 2017-06-20 | Novartis Ag | regime de dosagem para um modulador ou agonista do receptor s1p |
| HRP20200883T1 (hr) | 2012-08-17 | 2020-09-04 | Actelion Pharmaceuticals Ltd. | Postupak za pripremanje (2z,5z)-5-(3-kloro-4-((r)-2,3-dihidroksipropoksi)benziliden)-2-(propilimino)-3-(o-tolil)tiazolidin-4-ona i međuproizvodi koji se koriste u navedenom postupku |
| CN102887829B (zh) * | 2012-09-05 | 2014-07-02 | 中国科学院上海药物研究所 | 芬戈莫德粘酸盐及其晶体的制备方法和用途 |
| JP6401257B2 (ja) | 2013-10-11 | 2018-10-10 | テイコク ファーマ ユーエスエー インコーポレーテッド | 局所用スフィンゴシン−1−リン酸受容体アゴニスト製剤及びその使用方法 |
| WO2015053879A1 (en) | 2013-10-11 | 2015-04-16 | Teikoku Pharma Usa, Inc. | Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same |
| MA41139B1 (fr) | 2014-12-11 | 2026-02-27 | Laboratoires Juvise Pharmaceuticals | Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque |
| EA036075B1 (ru) | 2014-12-11 | 2020-09-23 | Актелион Фармасьютиклз Лтд | Схема дозирования для селективного агониста рецептора s1p1 |
| US20180042895A1 (en) | 2015-02-26 | 2018-02-15 | Novartis Ag | Treatment of autoimmune disease in a patient receiving additionally a beta-blocker |
| US10250466B2 (en) * | 2016-03-29 | 2019-04-02 | Juniper Networks, Inc. | Application signature generation and distribution |
| US11629124B2 (en) | 2017-03-09 | 2023-04-18 | Novartis Ag | Solid forms comprising an oxime ether compound, compositions and methods of use thereof |
| WO2021084068A1 (en) | 2019-10-31 | 2021-05-06 | Idorsia Pharmaceuticals Ltd | Combination of a cxcr7 antagonist with an s1p1 receptor modulator |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994008943A1 (fr) * | 1992-10-21 | 1994-04-28 | Yoshitomi Pharmaceutical Industries, Ltd. | Compose 2-amino-1,3-propanediol et immunosuppresseur |
| ATE211726T1 (de) | 1994-08-22 | 2002-01-15 | Welfide Corp | Benzolderivate und deren medizinische verwendung |
| HU224814B1 (en) * | 1995-12-28 | 2006-02-28 | Mitsubishi Pharma Corp | Use of propane-1,3-diol derivative for the preparation of a medicament useful for the topical treating of inflammatory and immune diseases |
| US6476004B1 (en) * | 1996-07-18 | 2002-11-05 | Mitsubishi Pharma Corporation | Pharmaceutical composition |
| KR20000075745A (ko) * | 1997-02-27 | 2000-12-26 | 가마후라 아키오 | 의약 조성물 |
| USRE39072E1 (en) | 1997-04-04 | 2006-04-18 | Mitsubishi Pharma Corporation | 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same |
| JPH1180026A (ja) * | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
| JPH11116479A (ja) * | 1997-10-10 | 1999-04-27 | Sugen Inc | 脳癌のための組み合わせ化学療法処置 |
| EP1300405B1 (en) | 2000-07-13 | 2007-04-18 | Sankyo Company, Limited | Amino alcohol derivatives |
| EP1315735A4 (en) | 2000-08-31 | 2005-04-06 | Merck & Co Inc | Phosphate derivatives as immunoregulatory compounds |
| MXPA03008755A (es) | 2001-03-26 | 2004-02-18 | Novartis Ag | Derivados de 2-amino-propanol. |
| WO2002080902A1 (en) * | 2001-04-02 | 2002-10-17 | Astrazeneca Ab | Solid pharmaceutical composition comprising 4 -cyano-trifluoro-3-(4-fluorophenylsulphonyl)-2-hydroxy-2-methylpropiono- m toluidide and pvp |
| EP1383532B1 (en) * | 2001-04-02 | 2011-05-04 | Genentech, Inc. | Combination therapy |
| JP2002316985A (ja) | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ベンゾチオフェン誘導体 |
| JP4476623B2 (ja) * | 2001-06-08 | 2010-06-09 | ノバルティス アーゲー | インスリン産生細胞移植片拒絶の処置または予防 |
| DE60235900D1 (de) | 2001-09-27 | 2010-05-20 | Kyorin Seiyaku Kk | Osuppressivum |
| CA2461212C (en) | 2001-09-27 | 2010-08-17 | Kyorin Pharmaceutical Co., Ltd. | Diaryl sulfide derivatives, salts thereof and immunosuppressive agents using the same |
| ATE441654T1 (de) | 2002-01-18 | 2009-09-15 | Merck & Co Inc | Edg-rezeptoragonisten |
| US20050070506A1 (en) | 2002-01-18 | 2005-03-31 | Doherty George A. | Selective s1p1/edg1 receptor agonists |
| AU2003202994B2 (en) | 2002-01-18 | 2007-11-22 | Merck Sharp & Dohme Corp. | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists |
| BR0314760A (pt) * | 2002-09-24 | 2005-07-26 | Novartis Ag | Compostos orgânicos |
| MY150088A (en) * | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
| WO2005000833A1 (en) | 2003-05-19 | 2005-01-06 | Irm, Llc | Immunosuppressant compounds and compositions |
| UA74941C2 (en) | 2004-04-26 | 2006-02-15 | Fos Internat S A | A metal-thermal process for producing magnesium and vacuum induction furnace for realizing the same |
| WO2005113330A1 (en) | 2004-05-05 | 2005-12-01 | Adler, Richard, S. | Systems and methods for protecting ship from attack on the surface or under water |
| WO2006041015A1 (ja) * | 2004-10-12 | 2006-04-20 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体とその付加塩及び免疫抑制剤 |
| CA2589265A1 (en) * | 2004-11-29 | 2006-06-01 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
| GT200600350A (es) * | 2005-08-09 | 2007-03-28 | Formulaciones líquidas |
-
2005
- 2005-11-28 CA CA002589265A patent/CA2589265A1/en not_active Abandoned
- 2005-11-28 ES ES05826219.7T patent/ES2495690T3/es not_active Expired - Lifetime
- 2005-11-28 PT PT58262197T patent/PT1819326E/pt unknown
- 2005-11-28 RU RU2007124327/15A patent/RU2478384C2/ru not_active IP Right Cessation
- 2005-11-28 JP JP2007543584A patent/JP2008521827A/ja not_active Withdrawn
- 2005-11-28 WO PCT/US2005/043044 patent/WO2006058316A1/en not_active Ceased
- 2005-11-28 CN CN2005800409686A patent/CN101068536B/zh not_active Expired - Fee Related
- 2005-11-28 SG SG200907947-6A patent/SG158096A1/en unknown
- 2005-11-28 NZ NZ554720A patent/NZ554720A/en not_active IP Right Cessation
- 2005-11-28 NZ NZ590054A patent/NZ590054A/en not_active IP Right Cessation
- 2005-11-28 US US11/720,205 patent/US20090275553A1/en not_active Abandoned
- 2005-11-28 BR BRPI0518674-9A patent/BRPI0518674A2/pt not_active Application Discontinuation
- 2005-11-28 EP EP05826219.7A patent/EP1819326B1/en not_active Revoked
- 2005-11-28 KR KR1020137008529A patent/KR20130041385A/ko not_active Ceased
- 2005-11-28 EP EP10179081A patent/EP2359821A1/en not_active Withdrawn
- 2005-11-28 CN CN2012100846463A patent/CN102600472A/zh active Pending
- 2005-11-28 AU AU2005309378A patent/AU2005309378B2/en not_active Ceased
- 2005-11-28 KR KR1020077011969A patent/KR20070085465A/ko not_active Ceased
- 2005-11-28 PL PL05826219T patent/PL1819326T3/pl unknown
- 2005-11-28 MX MX2007006373A patent/MX2007006373A/es active IP Right Grant
- 2005-11-28 EP EP10179083A patent/EP2384749A1/en not_active Withdrawn
- 2005-11-28 SG SG2013002662A patent/SG187468A1/en unknown
- 2005-11-28 KR KR20157005416A patent/KR20150028858A/ko not_active Ceased
- 2005-11-28 KR KR1020147018084A patent/KR20140095109A/ko not_active Withdrawn
-
2007
- 2007-04-24 ZA ZA200703328A patent/ZA200703328B/xx unknown
- 2007-05-10 IL IL183134A patent/IL183134A0/en unknown
- 2007-05-10 NO NO20072401A patent/NO20072401L/no not_active Application Discontinuation
- 2007-05-22 MA MA29926A patent/MA29034B1/fr unknown
- 2007-05-28 TN TNP2007000209A patent/TNSN07209A1/fr unknown
-
2011
- 2011-11-22 US US13/302,881 patent/US20120071446A1/en not_active Abandoned
-
2012
- 2012-02-27 JP JP2012040574A patent/JP2012107059A/ja not_active Withdrawn
- 2012-10-02 RU RU2012141951/15A patent/RU2012141951A/ru unknown
- 2012-11-06 NO NO20121305A patent/NO20121305L/no not_active Application Discontinuation
- 2012-12-06 IL IL223502A patent/IL223502A0/en unknown
-
2013
- 2013-03-05 JP JP2013043351A patent/JP2013129664A/ja not_active Withdrawn
-
2014
- 2014-10-16 US US14/516,153 patent/US20150087720A1/en not_active Abandoned
- 2014-12-26 JP JP2014266267A patent/JP2015061883A/ja active Pending
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