CA2589265A1 - Dosage regimen of an s1p receptor agonist - Google Patents
Dosage regimen of an s1p receptor agonist Download PDFInfo
- Publication number
- CA2589265A1 CA2589265A1 CA002589265A CA2589265A CA2589265A1 CA 2589265 A1 CA2589265 A1 CA 2589265A1 CA 002589265 A CA002589265 A CA 002589265A CA 2589265 A CA2589265 A CA 2589265A CA 2589265 A1 CA2589265 A1 CA 2589265A1
- Authority
- CA
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- Prior art keywords
- agonist
- daily dosage
- receptor modulator
- receptor
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
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Publications (1)
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| AU2005272619A1 (en) | 2004-08-13 | 2006-02-23 | Praecis Pharmaceuticals, Inc. | Methods and compositions for modulating sphingosine-1-phosphate (SIP) receptor activity |
| SG187468A1 (en) * | 2004-11-29 | 2013-02-28 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
| NZ588372A (en) * | 2005-09-09 | 2012-03-30 | Novartis Ag | Diphenyl ether or thioether derivatives for treatment of autoimmune diseases |
| GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
| CA2684953C (en) | 2007-05-04 | 2016-08-09 | Novartis Ag | Use of s1p receptor modulator |
| WO2009115954A1 (en) | 2008-03-17 | 2009-09-24 | Actelion Pharmaceuticals Ltd | Dosing regimen for a selective s1p1 receptor agonist |
| EP2305305A4 (en) * | 2008-05-20 | 2013-02-13 | Kyorin Seiyaku Kk | MEDIUM FOR INTRODUCTION / MAINTENANCE OF THE REMISSION |
| DK2307007T3 (da) | 2008-07-23 | 2014-11-10 | Novartis Ag | Sphingosin-1-phosphat-receptormodulatorer samt deres anvendelse til behandling af muskelinflammation |
| ES2526119T3 (es) | 2008-08-18 | 2015-01-07 | Novartis Ag | Derivado de azetidina para el tratamiento de neuropatías periféricas |
| EP2379499B1 (en) | 2008-12-18 | 2014-04-09 | Novartis AG | Hydrochloride salt of 1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl)-2-ethyl-benzyl)-azetidine-3-carboxylic acid |
| AU2009327405A1 (en) * | 2008-12-18 | 2011-06-30 | Novartis Ag | New polymorphic form of 1- (4- { l- [ (E) -4-cyclohexyl--3-trifluoromethyl-benzyloxyimino] -ethyl) -2-ethyl-benzy l) -azetidine-3-carboxylic |
| RS53041B (sr) * | 2008-12-18 | 2014-04-30 | Novartis Ag | Hemifumaratna so 1-[4-[1-(4-cikloheksil-3-trifluorometil-benziloksiimino)-etil]-2-etil-benzil]-azetidin-3-karboksilne kiseline |
| AU2015275246B2 (en) * | 2008-12-22 | 2018-02-01 | Novartis Ag | Dosage regimen for a S1P receptor agonist |
| PL2379067T3 (pl) * | 2008-12-22 | 2016-02-29 | Novartis Ag | Schemat dawkowania fingolimodu w leczeniu stwardnienia rozsianego |
| WO2010072703A1 (en) * | 2008-12-22 | 2010-07-01 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
| EP3061449A1 (en) * | 2009-09-29 | 2016-08-31 | Novartis AG | Dosage regimen of an s1p receptor modulator |
| US20110124605A1 (en) * | 2009-11-20 | 2011-05-26 | Shreeram Aradhye | Use of an S1P Receptor Agonist |
| US8791100B2 (en) | 2010-02-02 | 2014-07-29 | Novartis Ag | Aryl benzylamine compounds |
| AU2011249789B2 (en) * | 2010-05-06 | 2015-03-19 | Novartis Ag | Dosage regimen of diaryl sulfide derivatives |
| JP6111202B2 (ja) | 2011-01-07 | 2017-04-05 | ノバルティス アーゲー | 免疫抑制製剤 |
| US20150218090A1 (en) * | 2011-10-21 | 2015-08-06 | Novartis Ag | Dosage regimen for an s1p receptor modulator or agonist |
| SMT202000298T1 (it) | 2012-08-17 | 2020-07-08 | Actelion Pharmaceuticals Ltd | Processo per la produzione di (2z,5z)-5-(3-cloro-4((r)-2,3-diidrossipropossi) benziliden)-2-(propilimmino)-3-(o-tolil)tiazolidin-4-one e intermedio usato in detto processo |
| CN102887829B (zh) * | 2012-09-05 | 2014-07-02 | 中国科学院上海药物研究所 | 芬戈莫德粘酸盐及其晶体的制备方法和用途 |
| US10675254B2 (en) | 2013-10-11 | 2020-06-09 | Teikoku Seiyaku Co., Ltd. | Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same |
| US10022340B2 (en) | 2013-10-11 | 2018-07-17 | Teikoku Pharma Usa, Inc. | Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same |
| MA41139B1 (fr) | 2014-12-11 | 2026-02-27 | Laboratoires Juvise Pharmaceuticals | Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque |
| DK3256125T3 (da) | 2014-12-11 | 2022-03-21 | Actelion Pharmaceuticals Ltd | Doseringsregimen for ponesimod, en selektiv s1p1-receptoragonist |
| US20180042895A1 (en) | 2015-02-26 | 2018-02-15 | Novartis Ag | Treatment of autoimmune disease in a patient receiving additionally a beta-blocker |
| US10250466B2 (en) * | 2016-03-29 | 2019-04-02 | Juniper Networks, Inc. | Application signature generation and distribution |
| US11629124B2 (en) | 2017-03-09 | 2023-04-18 | Novartis Ag | Solid forms comprising an oxime ether compound, compositions and methods of use thereof |
| TW202131921A (zh) | 2019-10-31 | 2021-09-01 | 瑞士商愛杜西亞製藥有限公司 | Cxcr7拮抗劑與s1p1受體調節劑之組合 |
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| EP0627406B1 (en) | 1992-10-21 | 1998-10-28 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-amino-1,3-propanediol compound and immunosuppressant |
| JP3870419B2 (ja) | 1994-08-22 | 2007-01-17 | 三菱ウェルファーマ株式会社 | ベンゼン化合物およびその医薬としての用途 |
| ATE279185T1 (de) * | 1995-12-28 | 2004-10-15 | Mitsubishi Pharma Corp | 2-amino-2-(2-(4-octylphenyl)ethyl)propan-1,3-di l enthaltendes arzneimittel zur topischen anwendung zur behandlung von erkrankungen die durch eine störung des immunsystems hervorgerufen werden |
| US6476004B1 (en) * | 1996-07-18 | 2002-11-05 | Mitsubishi Pharma Corporation | Pharmaceutical composition |
| DE69840169D1 (de) * | 1997-02-27 | 2008-12-11 | Novartis Ag | Arzneimittel zubereitung enthaltend 2-amino-2-ä2-(4-octylphenyl)ethylüpropane-1,3-diol, ein lecithin und ein saccharid |
| CA2286315C (en) | 1997-04-04 | 2007-03-06 | Yoshitomi Pharmaceutical Industries Ltd. | 2-aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor |
| JPH1180026A (ja) * | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
| JPH11116479A (ja) * | 1997-10-10 | 1999-04-27 | Sugen Inc | 脳癌のための組み合わせ化学療法処置 |
| NZ533997A (en) | 2000-07-13 | 2005-11-25 | Sankyo Co | Amino alcohol derivatives |
| AU8533101A (en) | 2000-08-31 | 2002-03-13 | Merck & Co Inc | Phosphate derivatives as immunoregulatory agents |
| US7326801B2 (en) | 2001-03-26 | 2008-02-05 | Novartis Ag | 2-amino-propanol derivatives |
| ES2364816T3 (es) * | 2001-04-02 | 2011-09-14 | Genentech, Inc. | Terapia de combinación. |
| CA2443040A1 (en) * | 2001-04-02 | 2002-10-17 | Nicola Frances Bateman | Solid pharmaceutical composition comprising 4 -cyano-trifluoro-3-(4-fluorophenyl-sulphonyl) -2-hydroxy-2-methylpropiono- m toluidide and pvp |
| JP2002316985A (ja) | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ベンゾチオフェン誘導体 |
| NZ529044A (en) * | 2001-06-08 | 2008-03-28 | Novartis Ag | Treatment or prophylaxis of insulin-producing cell graft rejection |
| AU2002332289B2 (en) | 2001-09-27 | 2007-05-10 | Kyorin Pharmaceutical Co., Ltd. | Diaryl sulfide derivative, addition salt thereof, and immunosuppressant |
| ATE463478T1 (de) * | 2001-09-27 | 2010-04-15 | Kyorin Seiyaku Kk | Diaryletherderivat, dessen additionssalz und immunosuppressivum |
| ATE441654T1 (de) | 2002-01-18 | 2009-09-15 | Merck & Co Inc | Edg-rezeptoragonisten |
| US20050070506A1 (en) | 2002-01-18 | 2005-03-31 | Doherty George A. | Selective s1p1/edg1 receptor agonists |
| AU2003202994B2 (en) | 2002-01-18 | 2007-11-22 | Merck Sharp & Dohme Corp. | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists |
| MXPA05003254A (es) * | 2002-09-24 | 2005-06-08 | Novartis Ag | Agonistas del receptor de esfingosina-1-fosfato en el tratamiento de trastornos de desmielinacion. |
| AU2004251146A1 (en) | 2003-05-19 | 2005-01-06 | Irm, Llc | Immunosuppressant compounds and compositions |
| MY150088A (en) | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
| UA74941C2 (en) | 2004-04-26 | 2006-02-15 | Fos Internat S A | A metal-thermal process for producing magnesium and vacuum induction furnace for realizing the same |
| WO2005113330A1 (en) | 2004-05-05 | 2005-12-01 | Adler, Richard, S. | Systems and methods for protecting ship from attack on the surface or under water |
| WO2006041015A1 (ja) * | 2004-10-12 | 2006-04-20 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体とその付加塩及び免疫抑制剤 |
| SG187468A1 (en) * | 2004-11-29 | 2013-02-28 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
| GT200600350A (es) * | 2005-08-09 | 2007-03-28 | Formulaciones líquidas |
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- 2005-11-28 KR KR20157005416A patent/KR20150028858A/ko not_active Ceased
- 2005-11-28 SG SG200907947-6A patent/SG158096A1/en unknown
- 2005-11-28 CN CN2012100846463A patent/CN102600472A/zh active Pending
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2007
- 2007-04-24 ZA ZA200703328A patent/ZA200703328B/xx unknown
- 2007-05-10 NO NO20072401A patent/NO20072401L/no not_active Application Discontinuation
- 2007-05-10 IL IL183134A patent/IL183134A0/en unknown
- 2007-05-22 MA MA29926A patent/MA29034B1/fr unknown
- 2007-05-28 TN TNP2007000209A patent/TNSN07209A1/fr unknown
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2011
- 2011-11-22 US US13/302,881 patent/US20120071446A1/en not_active Abandoned
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2012
- 2012-02-27 JP JP2012040574A patent/JP2012107059A/ja not_active Withdrawn
- 2012-10-02 RU RU2012141951/15A patent/RU2012141951A/ru unknown
- 2012-11-06 NO NO20121305A patent/NO20121305L/no not_active Application Discontinuation
- 2012-12-06 IL IL223502A patent/IL223502A0/en unknown
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2013
- 2013-03-05 JP JP2013043351A patent/JP2013129664A/ja not_active Withdrawn
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2014
- 2014-10-16 US US14/516,153 patent/US20150087720A1/en not_active Abandoned
- 2014-12-26 JP JP2014266267A patent/JP2015061883A/ja active Pending
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| FZDE | Discontinued |
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