RU2478384C2 - Курс лечения с использованием агониста рецептора s1p - Google Patents
Курс лечения с использованием агониста рецептора s1p Download PDFInfo
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- RU2478384C2 RU2478384C2 RU2007124327/15A RU2007124327A RU2478384C2 RU 2478384 C2 RU2478384 C2 RU 2478384C2 RU 2007124327/15 A RU2007124327/15 A RU 2007124327/15A RU 2007124327 A RU2007124327 A RU 2007124327A RU 2478384 C2 RU2478384 C2 RU 2478384C2
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- Prior art keywords
- alkyl
- dose
- agonist
- fty720
- treatment
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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Landscapes
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
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| US63148304P | 2004-11-29 | 2004-11-29 | |
| US60/631,483 | 2004-11-29 | ||
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| RU2012141951/15A Division RU2012141951A (ru) | 2004-11-29 | 2012-10-02 | Курс лечения с использованием агониста рецептора sip |
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| RU2012141951/15A RU2012141951A (ru) | 2004-11-29 | 2012-10-02 | Курс лечения с использованием агониста рецептора sip |
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| EP (3) | EP2384749A1 (enExample) |
| JP (4) | JP2008521827A (enExample) |
| KR (4) | KR20070085465A (enExample) |
| CN (2) | CN102600472A (enExample) |
| AU (1) | AU2005309378B2 (enExample) |
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| CA (1) | CA2589265A1 (enExample) |
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| MA (1) | MA29034B1 (enExample) |
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| PT (1) | PT1819326E (enExample) |
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| BRPI0514316A (pt) | 2004-08-13 | 2008-06-10 | Praecis Pharm Inc | métodos e composições para modulação de atividade de receptor de esfingosina-1-fosfato (s1p) |
| EP2384749A1 (en) * | 2004-11-29 | 2011-11-09 | Novartis AG | Dosage regimen of an S1P receptor agonist |
| NZ566137A (en) * | 2005-09-09 | 2011-05-27 | Novartis Ag | The use of diphenyl thioether derivatives to treat autoimmune diseases |
| GB0612721D0 (en) * | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
| EP2142184B1 (en) | 2007-05-04 | 2018-10-24 | Novartis AG | Use of s1p receptor modulator |
| CA2716448A1 (en) * | 2008-03-17 | 2009-09-24 | Patrick Brossard | Dosing regimen for a selective s1p1 receptor agonist |
| EP2305305A4 (en) * | 2008-05-20 | 2013-02-13 | Kyorin Seiyaku Kk | MEDIUM FOR INTRODUCTION / MAINTENANCE OF THE REMISSION |
| RU2521286C2 (ru) * | 2008-07-23 | 2014-06-27 | Новартис Аг | Модуляторы рецептора сфингозин-1-фосфата (s1p) и их применение для лечения воспаления мышечной ткани |
| CA2733508A1 (en) * | 2008-08-18 | 2010-02-25 | David Leppert | Compounds for the treatment of peripheral neuropathies |
| AU2009327405A1 (en) * | 2008-12-18 | 2011-06-30 | Novartis Ag | New polymorphic form of 1- (4- { l- [ (E) -4-cyclohexyl--3-trifluoromethyl-benzyloxyimino] -ethyl) -2-ethyl-benzy l) -azetidine-3-carboxylic |
| HRP20131106T1 (hr) * | 2008-12-18 | 2013-12-20 | Novartis Ag | Hemifumaratna sol od 1-[4-[1-(4-cikloheksil-3-trifluorometil-benziloksiimino)-etil]-2-etil-benzil]-azetidin-3-karboksilne kiseline |
| RU2011129229A (ru) * | 2008-12-18 | 2013-01-27 | Новартис Аг | Новые соли |
| MX367667B (es) * | 2008-12-22 | 2019-08-30 | Novartis Ag | Régimen de dosificación de un agonista de los receptores de s1p. |
| US20100160259A1 (en) * | 2008-12-22 | 2010-06-24 | Robert Schmouder | Dosage regimen for a s1p receptor agonist |
| AU2015275246B2 (en) * | 2008-12-22 | 2018-02-01 | Novartis Ag | Dosage regimen for a S1P receptor agonist |
| EP3831371A1 (en) | 2009-09-29 | 2021-06-09 | Novartis AG | Dosage regimen of an s1p receptor modulator |
| US20110124605A1 (en) * | 2009-11-20 | 2011-05-26 | Shreeram Aradhye | Use of an S1P Receptor Agonist |
| US8791100B2 (en) | 2010-02-02 | 2014-07-29 | Novartis Ag | Aryl benzylamine compounds |
| WO2011138398A1 (en) * | 2010-05-06 | 2011-11-10 | Novartis Ag | Dosage regimen of diaryl sulfide derivatives |
| SG191286A1 (en) | 2011-01-07 | 2013-07-31 | Novartis Ag | Immunosuppressant formulations |
| CA2852142A1 (en) * | 2011-10-21 | 2013-04-25 | Novartis Ag | Dosage regimen for an s1p receptor modulator or agonist |
| HUE050733T2 (hu) | 2012-08-17 | 2021-01-28 | Actelion Pharmaceuticals Ltd | Eljárás (2Z,5Z)-5-(3-klór-4-((R)-2,3-dihidroxipropoxi)benzilidén)-2-(pro-pilimino)-3-(O-tolil)tiazolidin-4-on elõállítására és ezen eljárásban alkalmazott köztitermék |
| CN102887829B (zh) * | 2012-09-05 | 2014-07-02 | 中国科学院上海药物研究所 | 芬戈莫德粘酸盐及其晶体的制备方法和用途 |
| EP3054933A4 (en) | 2013-10-11 | 2017-03-15 | Teikoku Pharma USA, Inc. | Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same |
| WO2015053879A1 (en) | 2013-10-11 | 2015-04-16 | Teikoku Pharma Usa, Inc. | Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same |
| HUE057865T2 (hu) | 2014-12-11 | 2022-06-28 | Actelion Pharmaceuticals Ltd | A poneszimodra, egy szelektív S1P1 receptor agonistára vonatkozó adagolási rend |
| MA41139B1 (fr) | 2014-12-11 | 2026-02-27 | Laboratoires Juvise Pharmaceuticals | Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque |
| WO2016135644A1 (en) | 2015-02-26 | 2016-09-01 | Novartis Ag | Treatment of autoimmune disease in a patient receiving additionally a beta-blocker |
| US10250466B2 (en) * | 2016-03-29 | 2019-04-02 | Juniper Networks, Inc. | Application signature generation and distribution |
| US11629124B2 (en) | 2017-03-09 | 2023-04-18 | Novartis Ag | Solid forms comprising an oxime ether compound, compositions and methods of use thereof |
| CA3156298A1 (en) | 2019-10-31 | 2021-05-06 | Laetitia POUZOL | Combination of a cxcr7 antagonist with an s1p1 receptor modulator |
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| KR0155015B1 (ko) | 1992-10-21 | 1998-12-01 | 고우야 마사시 | 2-아미노-1,3-프로판디올 화합물 및 면역 억제제 |
| DE69524962T4 (de) | 1994-08-22 | 2003-08-28 | Mitsubishi Pharma Corp., Osaka | Benzolderivate und deren medizinische verwendung |
| WO1997024112A1 (en) * | 1995-12-28 | 1997-07-10 | Yoshitomi Pharmaceutical Industries, Ltd. | External preparation |
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| JPH11116479A (ja) * | 1997-10-10 | 1999-04-27 | Sugen Inc | 脳癌のための組み合わせ化学療法処置 |
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| WO2002018395A1 (en) | 2000-08-31 | 2002-03-07 | Merck & Co., Inc. | Phosphate derivatives as immunoregulatory agents |
| MXPA03008755A (es) | 2001-03-26 | 2004-02-18 | Novartis Ag | Derivados de 2-amino-propanol. |
| CZ20032647A3 (cs) * | 2001-04-02 | 2004-09-15 | Astrazeneca Ab | Pevná farmaceutická kompozice obsahující 4-kyanotrifluor-3-(4-fluorfenylsulfonyl)-2-hydroxy-2-methylpropiono-m-toluidin a PVP |
| JP4679035B2 (ja) * | 2001-04-02 | 2011-04-27 | ジェネンテック， インコーポレイテッド | 併用療法 |
| JP2002316985A (ja) | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ベンゾチオフェン誘導体 |
| ES2322442T3 (es) * | 2001-06-08 | 2009-06-22 | Novartis Ag | Tratamiento o profilaxis del rechazo de injertos de celulas productoras de insulina. |
| DE60329073D1 (de) | 2002-01-18 | 2009-10-15 | Merck & Co Inc | Edg-rezeptoragonisten |
| EP1469863A2 (en) | 2002-01-18 | 2004-10-27 | Merck & Co., Inc. | Selective s1p1/edg1 receptor agonists |
| ATE448193T1 (de) | 2002-01-18 | 2009-11-15 | Merck & Co Inc | ßN-(BENZYL)AMINOALKYL CARBOXYLATE, PHOSPHINATE, PHOSPHONATE UND TETRAZOLE ALS EDG REZEPTORAGONISTENß |
| MXPA05003254A (es) * | 2002-09-24 | 2005-06-08 | Novartis Ag | Agonistas del receptor de esfingosina-1-fosfato en el tratamiento de trastornos de desmielinacion. |
| EP1628967B1 (en) | 2003-05-19 | 2014-04-09 | Irm Llc | Immunosuppressant compounds and compositions |
| UA74941C2 (en) | 2004-04-26 | 2006-02-15 | Fos Internat S A | A metal-thermal process for producing magnesium and vacuum induction furnace for realizing the same |
| WO2005113330A1 (en) | 2004-05-05 | 2005-12-01 | Adler, Richard, S. | Systems and methods for protecting ship from attack on the surface or under water |
| JPWO2006041015A1 (ja) * | 2004-10-12 | 2008-05-15 | 杏林製薬株式会社 | アミノアルコール誘導体とその付加塩及び免疫抑制剤 |
| EP2384749A1 (en) * | 2004-11-29 | 2011-11-09 | Novartis AG | Dosage regimen of an S1P receptor agonist |
| GT200600350A (es) * | 2005-08-09 | 2007-03-28 | Formulaciones líquidas |
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- 2005-11-28 EP EP10179083A patent/EP2384749A1/en not_active Withdrawn
- 2005-11-28 CN CN2012100846463A patent/CN102600472A/zh active Pending
- 2005-11-28 PL PL05826219T patent/PL1819326T3/pl unknown
- 2005-11-28 RU RU2007124327/15A patent/RU2478384C2/ru not_active IP Right Cessation
- 2005-11-28 NZ NZ590054A patent/NZ590054A/en not_active IP Right Cessation
- 2005-11-28 CA CA002589265A patent/CA2589265A1/en not_active Abandoned
- 2005-11-28 SG SG200907947-6A patent/SG158096A1/en unknown
- 2005-11-28 KR KR1020077011969A patent/KR20070085465A/ko not_active Ceased
- 2005-11-28 MX MX2007006373A patent/MX2007006373A/es active IP Right Grant
- 2005-11-28 BR BRPI0518674-9A patent/BRPI0518674A2/pt not_active Application Discontinuation
- 2005-11-28 US US11/720,205 patent/US20090275553A1/en not_active Abandoned
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- 2005-11-28 CN CN2005800409686A patent/CN101068536B/zh not_active Expired - Fee Related
- 2005-11-28 EP EP10179081A patent/EP2359821A1/en not_active Withdrawn
- 2005-11-28 KR KR1020147018084A patent/KR20140095109A/ko not_active Withdrawn
- 2005-11-28 KR KR20157005416A patent/KR20150028858A/ko not_active Ceased
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