JP2007502806A5 - - Google Patents

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Publication number
JP2007502806A5
JP2007502806A5 JP2006523683A JP2006523683A JP2007502806A5 JP 2007502806 A5 JP2007502806 A5 JP 2007502806A5 JP 2006523683 A JP2006523683 A JP 2006523683A JP 2006523683 A JP2006523683 A JP 2006523683A JP 2007502806 A5 JP2007502806 A5 JP 2007502806A5
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JP
Japan
Prior art keywords
chloro
phenoxy
phenyl
acetic acid
methylsulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006523683A
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English (en)
Japanese (ja)
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JP2007502806A (ja
JP5025264B2 (ja
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Publication date
Priority claimed from SE0302281A external-priority patent/SE0302281D0/xx
Priority claimed from GB0412448A external-priority patent/GB0412448D0/en
Application filed filed Critical
Priority claimed from PCT/GB2004/003551 external-priority patent/WO2005018529A2/en
Publication of JP2007502806A publication Critical patent/JP2007502806A/ja
Publication of JP2007502806A5 publication Critical patent/JP2007502806A5/ja
Application granted granted Critical
Publication of JP5025264B2 publication Critical patent/JP5025264B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006523683A 2003-08-21 2004-08-18 フェノキシ酢酸誘導体 Expired - Fee Related JP5025264B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE0302281A SE0302281D0 (sv) 2003-08-21 2003-08-21 Novel compounds
SE0302281-1 2003-08-21
GB0412448A GB0412448D0 (en) 2004-06-04 2004-06-04 Novel compounds
GB0412448.3 2004-06-04
PCT/GB2004/003551 WO2005018529A2 (en) 2003-08-21 2004-08-18 Phenoxiacetic acid derivatives

Publications (3)

Publication Number Publication Date
JP2007502806A JP2007502806A (ja) 2007-02-15
JP2007502806A5 true JP2007502806A5 (enExample) 2007-07-12
JP5025264B2 JP5025264B2 (ja) 2012-09-12

Family

ID=34219638

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006523683A Expired - Fee Related JP5025264B2 (ja) 2003-08-21 2004-08-18 フェノキシ酢酸誘導体

Country Status (28)

Country Link
US (2) US8003703B2 (enExample)
EP (1) EP1660431B1 (enExample)
JP (1) JP5025264B2 (enExample)
KR (1) KR101136175B1 (enExample)
AR (1) AR045470A1 (enExample)
AT (1) ATE427296T1 (enExample)
AU (1) AU2004266485B2 (enExample)
BR (1) BRPI0413490A (enExample)
CA (1) CA2535714C (enExample)
CO (1) CO5670367A2 (enExample)
CY (1) CY1110318T1 (enExample)
DE (1) DE602004020356D1 (enExample)
DK (1) DK1660431T3 (enExample)
ES (1) ES2322653T3 (enExample)
HR (1) HRP20090280T1 (enExample)
IL (1) IL173522A (enExample)
IS (1) IS2693B (enExample)
MX (1) MXPA06001954A (enExample)
MY (1) MY142029A (enExample)
NZ (1) NZ545450A (enExample)
PL (1) PL1660431T3 (enExample)
PT (1) PT1660431E (enExample)
RU (1) RU2360901C2 (enExample)
SA (1) SA04250253B1 (enExample)
SI (1) SI1660431T1 (enExample)
TW (1) TWI347313B (enExample)
UY (1) UY28482A1 (enExample)
WO (1) WO2005018529A2 (enExample)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0301009D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SE0301010D0 (sv) 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
US7714132B2 (en) 2004-03-11 2010-05-11 Actelion Pharmaceuticals, Ltd. Tetrahydropyridoindole derivatives
JP2008500991A (ja) * 2004-05-29 2008-01-17 ７ティーエム ファーマ エイ／エス 医学的使用のためのｃｒｔｈ２レセプターリガンド
WO2005115374A1 (en) * 2004-05-29 2005-12-08 7Tm Pharma A/S Crth2 receptor ligands for therapeutic use
GB0415320D0 (en) * 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) * 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
GB0422057D0 (en) * 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
ATE517085T1 (de) * 2004-11-23 2011-08-15 Astrazeneca Ab Zur behandlung von atemwegserkrankungen geeignete phenoxyessigsäurederivate
GB0510585D0 (en) * 2005-05-24 2005-06-29 Novartis Ag Organic compounds
GB0510584D0 (en) * 2005-05-24 2005-06-29 Novartis Ag Organic compounds
DK1928457T3 (da) * 2005-09-30 2013-02-04 Pulmagen Therapeutics Asthma Ltd Quinoliner og deres terapeutiske anvendelse
GB0520324D0 (en) * 2005-10-06 2005-11-16 Astrazeneca Ab Novel compounds
RU2424229C2 (ru) * 2005-10-06 2011-07-20 Астразенека Аб Производные бифенилоксиуксусной кислоты, их применение для изготовления лекарственного средства и промежуточные соединения
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
WO2007039736A1 (en) 2005-10-06 2007-04-12 Astrazeneca Ab Novel compounds
EP1948630A2 (en) * 2005-11-05 2008-07-30 AstraZeneca AB Novel compounds
WO2007062678A1 (en) * 2005-11-29 2007-06-07 7Tm Pharma A/S Phenoxyacetic acid derivatives as crth2 receptor ligands
GB0524428D0 (en) 2005-11-30 2006-01-11 7Tm Pharma As Medicinal use of receptor ligands
WO2007068894A2 (en) 2005-12-15 2007-06-21 Astrazeneca Ab Substituted diphenylethers, -amines, -sulfides and -methanes for the treatment of respiratory disease
JP2009538289A (ja) 2006-05-26 2009-11-05 アストラゼネカ・アクチエボラーグ ビアリールまたはヘテロアリール置換インドール
HUE030850T2 (en) 2006-06-16 2017-06-28 Univ Pennsylvania Prostaglandin D2 receptor antagonists for the treatment of hair loss
GB0702456D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab New combination
SI2139881T1 (sl) * 2007-04-04 2012-05-31 Pulmagen Therapeutics Asthma Ltd Kinolini in njihova terapevtska raba
UA100983C2 (ru) * 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
NZ585888A (en) 2007-12-14 2012-02-24 Pulmagen Therapeutics Asthma Ltd Indoles and their therapeutic use
WO2009151910A2 (en) * 2008-05-25 2009-12-17 Wyeth Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
GB0818365D0 (en) * 2008-10-07 2008-11-12 Argenta Discovery Ltd Quinoline compounds
RS52809B (sr) * 2008-11-17 2013-10-31 F. Hoffmann-La Roche Ag. Naftilsirćetne kiseline
PT2452944E (pt) 2009-07-09 2014-10-13 Kyorin Seiyaku Kk Derivados de sulfureto de difenilo e medicamentos que os contêm como ingredientes activos
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
WO2011073662A1 (en) 2009-12-17 2011-06-23 Astrazeneca Ab Combination of a benzoxazinone and a further agent for treating respiratory diseases
TW201201805A (en) 2010-07-05 2012-01-16 Actelion Pharmaceuticals Ltd 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
EP2526945A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. New CRTH2 Antagonists
EP2548863A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists.
EP2548876A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists
KR20140113667A (ko) 2011-12-16 2014-09-24 아토픽스 테라퓨릭스 리미티드 호산구성 식도염의 치료를 위한 ｃｒｔｈ2 길항제 및 양성자 펌프 저해제의 조합
CN104011021B (zh) 2011-12-21 2016-08-24 埃科特莱茵药品有限公司 杂环衍生物及其作为前列腺素d2受体调节剂的用途
CN104602763B (zh) 2012-03-21 2018-08-21 宾夕法尼亚大学理事会 用于调节毛发生长的组合物和方法
US9169270B2 (en) 2012-07-05 2015-10-27 Actelion Pharmaceuticals Ltd. 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators
TW201623264A (zh) 2014-03-29 2016-07-01 魯賓有限公司 作為電位閘控鈉通道調節劑之磺胺化合物
WO2016128565A1 (en) 2015-02-13 2016-08-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) Ptgdr-1 and/or ptgdr-2 antagonists for preventing and/or treating systemic lupus erythematosus
RS60749B1 (sr) * 2015-05-27 2020-10-30 Jiangsu Hengrui Medicine Co Natrijumova so inhibitora transportera mokraćne kiseline i njen kristalni oblik
WO2017019858A1 (en) 2015-07-30 2017-02-02 The Trustees Of The University Of Pennsylvania Single nucleotide polymorphic alleles of human dp-2 gene for detection of susceptibility to hair growth inhibition by pgd2
WO2017097182A1 (zh) * 2015-12-07 2017-06-15 成都海创药业有限公司 喹啉类化合物及其制备方法和作为尿酸盐转运体抑制剂类药物的用途
GB201709396D0 (en) 2017-06-13 2017-07-26 Astrazeneca Ab Compounds for use as radioligands

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB690816A (en) 1950-01-02 1953-04-29 British Drug Houses Ltd Improvements in or relating to the manufacture of substituted phenoxy acetic acids
US3278524A (en) * 1962-03-13 1966-10-11 Beecham Group Ltd Penicillins and their production
CH432119A (de) * 1963-02-22 1967-03-15 Geigy Ag J R Verwendung von Halogen-o-hydroxy-diphenyläthern als antimikrobielle Mittel
BE790679A (fr) 1971-11-03 1973-04-27 Ici Ltd Derives de l'indole
DD113545A5 (enExample) 1973-03-30 1975-06-12
JPS5239888B2 (enExample) * 1973-05-28 1977-10-07
US3954852A (en) 1973-10-19 1976-05-04 Merck & Co., Inc. Indenylacetic acid compounds
CH582476A5 (enExample) * 1973-10-29 1976-12-15 Ciba Geigy Ag
DE2451140A1 (de) * 1973-10-29 1975-04-30 Eisai Co Ltd M-phenoxyphenylpropionsaeurederivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
GB1585963A (en) * 1976-10-14 1981-03-11 Lilly Industries Ltd Aryl sulphur compounds
US4248618A (en) * 1977-05-06 1981-02-03 Ici Australia Limited Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof
DE2832435A1 (de) 1977-07-27 1979-02-08 Ciba Geigy Ag Phenoxy-phenoxy-alkancarbonsaeurederivate
FR2428629A1 (fr) 1978-06-14 1980-01-11 Hexachimie Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体
GB2041363B (en) 1979-01-19 1982-10-06 Pfizer Ltd N-benzyl-imidazoles
US4670566A (en) * 1979-07-12 1987-06-02 A. H. Robins Company, Incorporated 3-methyl-hio-4-(5-, 6-, or 7-)phenylindolindolin-2-ones
US4486593A (en) 1983-01-19 1984-12-04 The Upjohn Company 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors
DE3419009A1 (de) * 1984-05-22 1985-11-28 Dr. Karl Thomae Gmbh, 7950 Biberach Neue substituierte bis(4-aminophenyl)sulfone, ihre herstellung und ihre verwendung als arzneimittel
US5006542A (en) * 1988-10-31 1991-04-09 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5145790A (en) 1990-05-04 1992-09-08 Abbott Laboratories Reagents and method for detecting polychlorinated biphenyls
EP0540165A1 (en) 1991-10-03 1993-05-05 Zeneca Limited Alkanoic acid derivatives
WO1993012086A1 (fr) 1991-12-11 1993-06-24 Ss Pharmaceutical Co., Ltd. Derive d'arylamide
CA2090283A1 (en) * 1992-02-28 1993-08-29 Nobuyuki Hamanaka Phenoxyacetic acid derivatives
EP0607536B1 (en) * 1992-12-08 2001-01-24 Ss Pharmaceutical Co., Ltd. Arylamide derivatives
JPH06313995A (ja) * 1993-04-28 1994-11-08 Hodogaya Chem Co Ltd 静電荷像現像用トナー
EP0622816B1 (en) 1993-04-30 1998-07-22 Kabushiki Kaisha Meidensha Electrode and process for forming an electrode material
JPH07140725A (ja) 1993-06-25 1995-06-02 Hodogaya Chem Co Ltd 負帯電性トナー用摩擦帯電付与部材
BR9610207A (pt) 1995-08-28 1999-02-02 American Home Prod Acidos fenóxi acéticos como inibidores da aldose redutase e agentes anti-hiperglicêmicos
DE19544828A1 (de) 1995-12-01 1997-06-05 Hoechst Ag Hochmolekulare Copolymere
CA2260859A1 (en) 1996-07-22 1998-01-29 Monsanto Company Thiol sulfone metalloprotease inhibitors
EP0839808A1 (en) 1996-10-29 1998-05-06 Novartis AG Pyrazole derivatives, processes for their preparation, and their use as herbicides
FR2763588B1 (fr) * 1997-05-23 1999-07-09 Cird Galderma Composes triaromatiques, compositions les contenant et utilisations
CO4960662A1 (es) 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
US5942532A (en) 1997-09-05 1999-08-24 Ortho Pharmaceutical Corporation 2-substituted phenyl-benzimidazole antibacterial agents
WO1999014194A1 (en) 1997-09-12 1999-03-25 Merck Frosst Canada & Co. 2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2
KR100340273B1 (ko) * 1997-10-14 2002-06-14 야마모토 카즈모토 비페닐-5-알칸산 유도체 및 이의 용도
JP3486408B2 (ja) 1999-08-23 2004-01-13 株式会社ビー・エム・エル 物質のヒトプロスタグランジンｄ２受容体に対する性質の同定方法
DK1206457T3 (da) * 1999-08-27 2004-02-16 Lilly Co Eli Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER
US6770666B2 (en) 1999-12-27 2004-08-03 Japan Tobacco Inc. Fused-ring compounds and use thereof as drugs
EP1259494A4 (en) 2000-02-18 2004-09-15 Merck & Co Inc ARYLOXYACETIC ACIDS FOR DIABETES AND LIPID DISORDERS
CA2405170A1 (en) 2000-04-24 2001-11-01 Merck Frosst Canada & Co. Method of treatment using phenyl and biaryl derivatives as prostaglandin e inhibitors and compounds useful therefore
IL152682A0 (en) 2000-05-31 2003-06-24 Astrazeneca Ab Indole derivatives with vascular damaging activity
IL153688A0 (en) * 2000-06-28 2003-07-06 Teva Pharma Carvedilol
US6878522B2 (en) 2000-07-07 2005-04-12 Baiyong Li Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2
US20040097555A1 (en) * 2000-12-26 2004-05-20 Shinegori Ohkawa Concomitant drugs
WO2002094770A2 (en) 2001-05-24 2002-11-28 Fujisawa Pharmaceutical Co., Ltd. Aminoalcohol derivatives
WO2002100399A1 (en) * 2001-06-12 2002-12-19 Elan Pharmaceuticals, Inc. Macrocycles useful in the treatment of alzheimer's disease
KR20040044856A (ko) 2001-09-07 2004-05-31 오노 야꾸힝 고교 가부시키가이샤 인돌 유도체 화합물
EP1501826B1 (en) 2002-02-01 2006-09-27 F. Hoffman-la Roche AG Substituted indoles as alpha-1 agonists
SE0200411D0 (sv) 2002-02-05 2002-02-05 Astrazeneca Ab Novel use
WO2003068744A1 (en) * 2002-02-18 2003-08-21 Ishihara Sangyo Kaisha, Ltd. Pyridine derivatives or salts thereof and cytokine production inhibitors containing the same
BR0308537A (pt) * 2002-03-20 2005-02-09 Metabolex Inc Composto, composição, e métodos para tratar diabetes tipo 2 e hiperuricemia, para modular resistência a insulina e para aliviar hiperlipidemia em um indivìduo e agente de prodroga
WO2003097598A1 (en) 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Compound exhibiting pgd 2 receptor antagonism
WO2003097042A1 (en) * 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Pgd2 receptor antagonist
SE0201635D0 (sv) 2002-05-30 2002-05-30 Astrazeneca Ab Novel compounds
SE0202241D0 (sv) 2002-07-17 2002-07-17 Astrazeneca Ab Novel Compounds
AR042206A1 (es) 2002-11-26 2005-06-15 Novartis Ag Acidos fenilaceticos y derivados
NZ541234A (en) 2002-12-20 2008-06-30 Amgen Inc Asthma and allergic inflammation modulators
CN1768040A (zh) 2003-03-28 2006-05-03 伊莱利利公司 作为akt(蛋白激酶b)抑制剂的异喹啉－5－磺酸酰胺
SE0301009D0 (sv) 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SE0301010D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
ES2257616T3 (es) 2003-04-25 2006-08-01 Actimis Pharmaceuticals, Inc. Derivados del acido pirimidinilacetico utiles para el tratamiento de enfermedades mediadas por crth2.
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0324763D0 (en) 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
US7166738B2 (en) * 2004-04-23 2007-01-23 Roche Palo Alto Llc Non-nucleoside reverse transcriptase inhibitors
GB0409921D0 (en) 2004-05-04 2004-06-09 Novartis Ag Organic compounds
JP2008500991A (ja) 2004-05-29 2008-01-17 ７ティーエム ファーマ エイ／エス 医学的使用のためのｃｒｔｈ２レセプターリガンド
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) * 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
GB0422057D0 (en) 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
ATE517085T1 (de) 2004-11-23 2011-08-15 Astrazeneca Ab Zur behandlung von atemwegserkrankungen geeignete phenoxyessigsäurederivate
GB0510584D0 (en) 2005-05-24 2005-06-29 Novartis Ag Organic compounds
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
WO2007039736A1 (en) 2005-10-06 2007-04-12 Astrazeneca Ab Novel compounds
EP1948630A2 (en) * 2005-11-05 2008-07-30 AstraZeneca AB Novel compounds
WO2007068894A2 (en) 2005-12-15 2007-06-21 Astrazeneca Ab Substituted diphenylethers, -amines, -sulfides and -methanes for the treatment of respiratory disease
UA100983C2 (ru) * 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты

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