CO4960662A1 - Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados - Google Patents

Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados

Info

Publication number
CO4960662A1
CO4960662A1 CO98045813A CO98045813A CO4960662A1 CO 4960662 A1 CO4960662 A1 CO 4960662A1 CO 98045813 A CO98045813 A CO 98045813A CO 98045813 A CO98045813 A CO 98045813A CO 4960662 A1 CO4960662 A1 CO 4960662A1
Authority
CO
Colombia
Prior art keywords
fluorine
derivatives
alkyl
certain
chlorine
Prior art date
Application number
CO98045813A
Other languages
English (en)
Inventor
Roger M Fujimoto
Wighton Mcquire Leslie
Mugrage Benjamin Biro
Duzer John Henry Van
Xu Daqiang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26736901&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO4960662(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO4960662A1 publication Critical patent/CO4960662A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

La presente invención se relaciona con compuestos de laFórmula (I): en donde R es metilo o etilo; R1 es cloro o flúor; R2 es hidrógeno o flúor; R3 es hidrógeno, flúor, cloro, metilo, etilo, metoxi, etoxi, o hidroxi; R4 es hidrógeno o flúor; y R5 es cloro, flúor, trifluorometilo, o metilo; sales farmacéuticamente aceptables de los mismos; como inhibidores de ciclo-oxigenasa COX-2 selectivos.
CO98045813A 1997-08-28 1998-08-11 Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados CO4960662A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5780397P 1997-08-28 1997-08-28
US6983797P 1997-08-28 1997-08-28

Publications (1)

Publication Number Publication Date
CO4960662A1 true CO4960662A1 (es) 2000-09-25

Family

ID=26736901

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98045813A CO4960662A1 (es) 1997-08-28 1998-08-11 Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados

Country Status (35)

Country Link
US (5) US6291523B1 (es)
EP (1) EP1007505B1 (es)
JP (1) JP3704470B2 (es)
KR (1) KR100637296B1 (es)
CN (1) CN1140500C (es)
AR (1) AR015157A1 (es)
AT (1) ATE237580T1 (es)
AU (1) AU743371B2 (es)
BR (1) BR9812010B1 (es)
CA (1) CA2298033C (es)
CO (1) CO4960662A1 (es)
CY (1) CY2007020I2 (es)
CZ (1) CZ298522B6 (es)
DE (4) DE122007000035I2 (es)
DK (1) DK1007505T3 (es)
ES (1) ES2197508T3 (es)
FR (1) FR09C0011I2 (es)
HK (1) HK1031374A1 (es)
HU (1) HU225774B1 (es)
ID (1) ID23953A (es)
IL (2) IL134498A0 (es)
LU (2) LU91346I2 (es)
MY (1) MY127881A (es)
NL (1) NL300379I2 (es)
NO (2) NO326196B1 (es)
NZ (1) NZ502669A (es)
PE (1) PE108099A1 (es)
PL (1) PL194480B1 (es)
PT (1) PT1007505E (es)
RU (1) RU2186762C2 (es)
SI (1) SI1007505T1 (es)
SK (1) SK283773B6 (es)
TR (1) TR200000447T2 (es)
TW (1) TWI250142B (es)
WO (1) WO1999011605A1 (es)

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