ES8404783A1 - Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico. - Google Patents

Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico.

Info

Publication number
ES8404783A1
ES8404783A1 ES520813A ES520813A ES8404783A1 ES 8404783 A1 ES8404783 A1 ES 8404783A1 ES 520813 A ES520813 A ES 520813A ES 520813 A ES520813 A ES 520813A ES 8404783 A1 ES8404783 A1 ES 8404783A1
Authority
ES
Spain
Prior art keywords
dichlorophenyl
phenylacetoxyacetyl
therapeutics
amine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES520813A
Other languages
English (en)
Other versions
ES520813A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodesfarma SA
Original Assignee
Prodes SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8485497&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8404783(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prodes SA filed Critical Prodes SA
Priority to ES520813A priority Critical patent/ES520813A0/es
Priority to US06/590,018 priority patent/US4548952A/en
Priority to EP84400549A priority patent/EP0119932B1/en
Priority to AT84400549T priority patent/ATE27144T1/de
Priority to DE8484400549T priority patent/DE3463650D1/de
Priority to DE19843463650 priority patent/DE19875018I2/de
Priority to JP59054144A priority patent/JPS59205347A/ja
Publication of ES8404783A1 publication Critical patent/ES8404783A1/es
Publication of ES520813A0 publication Critical patent/ES520813A0/es
Priority to LU90073C priority patent/LU90073I2/fr
Priority to NL980015C priority patent/NL980015I1/nl
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

PROCEDIMIENTO PARA LA OBTENCION DEL ESTER DEL ACIDO 2-(2,6-DICLOROFENIL)AMINOBENCENOACETICO CON ACIO GLICOLICO.CONSISTE EN LA REACCION DE LA SAL SODICA DEL ACIDO 2-2,6-DICLOROFENIL)AMINOBENCEN OACETICO CON BROMOACETATO DE BENCILO, EN UN DISOLVENTE ORGANICO, TAL COMO DIMETILFORMAMIDA, A UNA TEMPERATURA PROXIMA A 50JC; SEGUIDA DE LA REDUCCION CATALITICA DEL PRODUCTO FORMADO, MEDIANTE TRATAMIENTO CON HIDROGENO EN EL SENDO DE ACIDO ACETICO Y EN PRESENCIA DE PD/C AL 10.ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS POR SU ACCION ANTIINFLAMATORIA.
ES520813A 1983-03-21 1983-03-21 Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico. Granted ES520813A0 (es)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ES520813A ES520813A0 (es) 1983-03-21 1983-03-21 Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico.
US06/590,018 US4548952A (en) 1983-03-21 1984-03-15 2-[(2,6-Dichlorophenyl)amino]phenylacetoxyacetyl derivatives and therapeutic compositions containing same
DE19843463650 DE19875018I2 (de) 1983-03-21 1984-03-19 2-Ä(2,6-Dichlorphenyl)aminoÜphenylacetoxyessigs{urederivate, das Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung
DE8484400549T DE3463650D1 (en) 1983-03-21 1984-03-19 New 2-((2,6-dichlorophenyl)amine)phenylacetoxyacetyl derivatives, the process for preparing the same and their use in therapeutics
AT84400549T ATE27144T1 (de) 1983-03-21 1984-03-19 2-((2,6es830321
EP84400549A EP0119932B1 (en) 1983-03-21 1984-03-19 New 2-((2,6-dichlorophenyl)amine)phenylacetoxyacetyl derivatives, the process for preparing the same and their use in therapeutics
JP59054144A JPS59205347A (ja) 1983-03-21 1984-03-21 新規な２−〔（２，６−ジクロロフエニル）アミノ〕フエニルアセトキシアセチル誘導体、その製造法およびその治療用組成物
LU90073C LU90073I2 (fr) 1983-03-21 1997-06-04 Aceclofenac et ses sels et dérivés pharmaceutiquement acceptables (Air-tal)
NL980015C NL980015I1 (nl) 1983-03-21 1998-04-16 Nieuwe 2-c(2,6-dichloorfenyl)amine!fenylacetoxyacetylderivaten, werkwijze voor de bereiding ervan enhun therapeutisch gebruik.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES520813A ES520813A0 (es) 1983-03-21 1983-03-21 Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico.

Publications (2)

Publication Number Publication Date
ES8404783A1 true ES8404783A1 (es) 1984-05-16
ES520813A0 ES520813A0 (es) 1984-05-16

Family

ID=8485497

Family Applications (1)

Application Number Title Priority Date Filing Date
ES520813A Granted ES520813A0 (es) 1983-03-21 1983-03-21 Procedimiento para la obtencion del ester del acido 2-(2,6-diclorofenil)amino bencenoacetico con acido glicolico.

Country Status (8)

Country Link
US (1) US4548952A (es)
EP (1) EP0119932B1 (es)
JP (1) JPS59205347A (es)
AT (1) ATE27144T1 (es)
DE (2) DE3463650D1 (es)
ES (1) ES520813A0 (es)
LU (1) LU90073I2 (es)
NL (1) NL980015I1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2046141A1 (es) * 1992-07-15 1994-01-16 Prodesfarma Sa "procedimiento para la obtencion del acido 2-((2,6-diclorofenil)amino) fenilacetoxiacetico"

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK8502611A (es) * 1985-08-08 1986-12-12
GB8717997D0 (en) * 1987-07-29 1987-09-03 Inverni Della Beffa Spa Derivatives of benzoyloxyacetic acid
ATE178884T1 (de) * 1994-06-29 1999-04-15 Novartis Erfind Verwalt Gmbh Salze von 2-((2,6- dichlorophenyl)amin>phenylacetoxyessigsäure mit organischen basischen kationen
ES2092962B1 (es) * 1995-04-19 1997-07-16 Prodes Sa Esteres nitricos de derivados del acido 2-(2,6-dihalofenilamino) fenilacetoxiacetico y sus procedimientos de preparacion.
CO4960662A1 (es) 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
KR100342365B1 (ko) * 1998-06-18 2002-11-11 국제약품공업주식회사 2-[(2,6-디클로로페닐)아미노]페닐아세톡시아세트산의제조방법
KR100335852B1 (ko) * 1998-08-21 2003-02-11 민연식 페닐아세톡시아세트산유도체의제조방법
KR100354271B1 (ko) * 2000-02-02 2002-09-28 신풍제약주식회사 아세클로페낙 및 그 중간체의 제조방법
US6818613B2 (en) * 2001-11-07 2004-11-16 Ortho-Mcneil Pharmaceutical, Inc. Aqueous sustained-release formulations of proteins
PE20040844A1 (es) * 2002-11-26 2004-12-30 Novartis Ag Acidos fenilaceticos y derivados como inhibidores de la cox-2
CN102924313A (zh) * 2012-11-13 2013-02-13 江苏吉贝尔药业有限公司 一种新的醋氯芬酸苄酯的制备方法
CN103086907B (zh) * 2013-02-06 2014-10-08 河南东泰制药有限公司 一种醋氯芬酸的制备方法
CN108383745B (zh) * 2018-05-08 2021-12-28 鲁南制药集团股份有限公司 一种醋氯芬酸的制备方法
CA3108680A1 (en) 2018-08-13 2020-02-20 AMEZCUA AMEZCUA, Federico Sinergic pharmaceutical composition of aceclofenac and betamethasone for the treatment of pain in localized forms of rheumatic conditions
MX2019000312A (es) 2019-01-08 2019-10-09 Federico Amezcua Amezcua Composicion farmaceutica sinergica de aceclofenaco y betametasona para el tratamiento del dolor de afecciones reumaticas o dolor postquirurgico.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137301C (es) * 1966-03-30
FR1604832A (en) * 1968-06-05 1972-04-17 Anilino phenyl acetyl esters of salicylic acid - - antiinflammatories analgesics and antipyretics

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2046141A1 (es) * 1992-07-15 1994-01-16 Prodesfarma Sa "procedimiento para la obtencion del acido 2-((2,6-diclorofenil)amino) fenilacetoxiacetico"

Also Published As

Publication number Publication date
DE19875018I2 (de) 2007-01-04
JPS59205347A (ja) 1984-11-20
DE3463650D1 (en) 1987-06-19
NL980015I1 (nl) 1998-07-01
ES520813A0 (es) 1984-05-16
ATE27144T1 (de) 1987-05-15
EP0119932B1 (en) 1987-05-13
EP0119932A1 (en) 1984-09-26
US4548952A (en) 1985-10-22
JPH0220627B2 (es) 1990-05-10
LU90073I2 (fr) 1997-08-21

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20060616