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Priority claimed from JP12673879Aexternal-prioritypatent/JPS5651461A/ja
Priority claimed from JP13358279Aexternal-prioritypatent/JPS5657768A/ja
Priority claimed from JP14198779Aexternal-prioritypatent/JPS5665877A/ja
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Publication of ES487014A0publicationCriticalpatent/ES487014A0/es
Publication of ES8102102A1publicationCriticalpatent/ES8102102A1/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE 4(3H)-QUINOAZOLINONAS SUSTITUIDAS, DE FORMULA (I), DONDE R1 Y R3 SON GRUPOS ALCOHILO, R2 ES UN GRUPO ALCOXICARBONILO, R4 PUEDE SER HIDROGENO O DIFERENTES RADICALES Y Q ES UN RESTO AROMATICO SITUADO EN LA POSICION 3. EL PROCEDIMIENTO DE OBTENCION SE INICIA CON LA REACCION DE UN COMPUESTO DE FORMULA (II) CON EL COMPUESTO DE FORMULA (III), DONDE ES UN ATOMO DE HALOGENO O UN GRUPO DE FORMULA (IV). A CONTINUACION SE HACE REACCIONAR EL PRODUCTO RESULTANTE CON UN COMPUESTO DE FORMULA (V), PARA POSTERIORMENTE HIDROLIZAR O REDUCIR, SEGUN CASOS, EL PRODUCTO OBTENIDO. ESTOS COMPUESTOS PRESENTAN ACTICIDAD FARMACOLOGICA COMO AGENTES VASODILATADORES, HIPOTENSORES Y ANTIARTEROESCLEROTICOS. *FORMULA*
ES487014A1978-12-191979-12-18Un procedimiento para obtener 4(3h)-quinazolinonas sustitui-das con un resto aromatico en la posicion 3
ExpiredES8102102A1
(es)