JPS5651461A - Novel 3-phenyl-4-quinazolone derivative - Google Patents

Novel 3-phenyl-4-quinazolone derivative

Info

Publication number
JPS5651461A
JPS5651461A JP12673879A JP12673879A JPS5651461A JP S5651461 A JPS5651461 A JP S5651461A JP 12673879 A JP12673879 A JP 12673879A JP 12673879 A JP12673879 A JP 12673879A JP S5651461 A JPS5651461 A JP S5651461A
Authority
JP
Japan
Prior art keywords
compound shown
alkyl
formula
phenyl
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12673879A
Other languages
Japanese (ja)
Inventor
Masayuki Ishikawa
Masao Eguchi
Hiromichi Tanaka
Shigeru Ito
Yoshimi Takashima
Masahiko Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP12673879A priority Critical patent/JPS5651461A/en
Priority to NZ192392A priority patent/NZ192392A/en
Priority to YU03063/79A priority patent/YU306379A/en
Priority to US06/103,841 priority patent/US4276295A/en
Priority to DE19792950376 priority patent/DE2950376A1/en
Priority to SE7910376A priority patent/SE7910376L/en
Priority to IT28062/79A priority patent/IT1126577B/en
Priority to AR279316A priority patent/AR225028A1/en
Priority to AU53932/79A priority patent/AU526309B2/en
Priority to GB7943565A priority patent/GB2040927B/en
Priority to NO794135A priority patent/NO794135L/en
Priority to NL7909118A priority patent/NL7909118A/en
Priority to ES487014A priority patent/ES487014A0/en
Priority to DK539979A priority patent/DK539979A/en
Priority to CH1125779A priority patent/CH644112A5/en
Priority to FR7931059A priority patent/FR2444671A1/en
Priority to DD79217854A priority patent/DD150462A5/en
Priority to CA342,295A priority patent/CA1111849A/en
Priority to HU79II311A priority patent/HU182733B/en
Priority to ES493758A priority patent/ES493758A0/en
Publication of JPS5651461A publication Critical patent/JPS5651461A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formula I (R1 and R2 are lower alkyl; R3 and R5 is alkyl; R4 are H, halogen, alkyl, or alkoxy; R6 is H, halogen, alkyl, alkoxy, CF3, or NO2; R4 and R5 may form methylenedioxy).
EXAMPLE: 7-Ethoxycarbonyl-6,8-dimethyl-3-(2'-chlorophenyl)-4-quinazolone.
USE: A vasodilator, blood stream improving agent, or hypotensor.
PROCESS: One mole compound shown by the formula I (R is H or lower alkyl), e.g., 5-ethoxycarbonyl-2-methoxycarbonyl-4,6-dimethylaniline, etc. is reacted 1W 1.2mol compound shown by the formula III, e.g., N,N-di-(2'-chlorophenyl)-formamidine, etc. in a proper solvent with uniform stirring at about 200°C for 1W5hr to give a compound shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP12673879A 1978-12-19 1979-10-03 Novel 3-phenyl-4-quinazolone derivative Pending JPS5651461A (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
JP12673879A JPS5651461A (en) 1979-10-03 1979-10-03 Novel 3-phenyl-4-quinazolone derivative
NZ192392A NZ192392A (en) 1978-12-19 1979-12-13 3-(substituted (phenyl or pyridyl)) -3,4-dihydroquinazolin-4-ones
YU03063/79A YU306379A (en) 1978-12-19 1979-12-14 Process for producing 3-aromatically substituted 4(3h)-quinazolines
US06/103,841 US4276295A (en) 1978-12-19 1979-12-14 3-Aromatic moiety substituted-4(3H)-quinazolinones, process for production thereof, and use thereof
DE19792950376 DE2950376A1 (en) 1978-12-19 1979-12-14 4 (3H) -QUINAZOLINONES SUBSTITUTED IN A 3-POSITION WITH AROMATIC GROUP AND METHOD FOR THE PRODUCTION AND USE THEREOF
SE7910376A SE7910376L (en) 1978-12-19 1979-12-17 quinazolinone derivatives
IT28062/79A IT1126577B (en) 1978-12-19 1979-12-17 4 (3H) -CHINAZOLINONES REPLACED IN THE 3-AROMATIC HALF, PROCEDURE FOR THEIR PRODUCTION AND USE
AR279316A AR225028A1 (en) 1978-12-19 1979-12-17 A PROCEDURE FOR PRODUCING A 4 (3H) -QUINAZOLINONE 3-PHENYL OR PIRIDIL-SUBSTITUTED
AU53932/79A AU526309B2 (en) 1978-12-19 1979-12-17 Substituted quinazolinones
GB7943565A GB2040927B (en) 1978-12-19 1979-12-18 Pharmaceutically active 3 - aromatic moiety substituted - 4 (3h) - quinazolinone derivatives
NO794135A NO794135L (en) 1978-12-19 1979-12-18 SUBSTITUTED 4 (3H) CHINAZOLINONES, PROCEDURE FOR THE PREPARATION AND USE OF THESE
NL7909118A NL7909118A (en) 1978-12-19 1979-12-18 SUBSTITUTED CHINAZOLIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES AS AN ACTIVE COMPONENT.
ES487014A ES487014A0 (en) 1978-12-19 1979-12-18 A PROCEDURE TO OBTAIN 4 (3H) -QUINAZOLINONES REPLACED WITH AN AROMATIC REST IN POSITION 3
DK539979A DK539979A (en) 1978-12-19 1979-12-18 QUINAZOLINO DERIVATIVES AND THEIR PREPARATION AND USE
CH1125779A CH644112A5 (en) 1978-12-19 1979-12-19 3-AROMATIC-SUBSTITUTED-4 (3H) CHINAZOLINONES AND METHOD FOR THE PRODUCTION THEREOF.
FR7931059A FR2444671A1 (en) 1978-12-19 1979-12-19 NEW QUINAZOLINONES, THEIR PREPARATION AND THE MEDICINE CONTAINING THESE SUBSTANCES
DD79217854A DD150462A5 (en) 1978-12-19 1979-12-19 PROCESS FOR PREPARING 4 (3H) -CHINAZOLINONES SUBSTITUTED IN 3-POSITION WITH AROMATIC GROUP
CA342,295A CA1111849A (en) 1978-12-19 1979-12-19 3-aromatic moiety substituted-4(3h)-quinazolinones, process for production thereof, and use thereof
HU79II311A HU182733B (en) 1978-12-19 1979-12-19 Process for producing substituted quinazoline-derivatives
ES493758A ES493758A0 (en) 1978-12-19 1980-07-28 A PROCEDURE FOR PRODUCING A 4 (3H) -QUINAZOLINONE SUBSTITUTED WITH AN AROMATIC REST IN POSITION 3Ÿ

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12673879A JPS5651461A (en) 1979-10-03 1979-10-03 Novel 3-phenyl-4-quinazolone derivative

Publications (1)

Publication Number Publication Date
JPS5651461A true JPS5651461A (en) 1981-05-09

Family

ID=14942667

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12673879A Pending JPS5651461A (en) 1978-12-19 1979-10-03 Novel 3-phenyl-4-quinazolone derivative

Country Status (1)

Country Link
JP (1) JPS5651461A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008156358A (en) * 2004-02-13 2008-07-10 Banyu Pharmaceut Co Ltd Fused ring 4-oxopyrimidine derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008156358A (en) * 2004-02-13 2008-07-10 Banyu Pharmaceut Co Ltd Fused ring 4-oxopyrimidine derivative

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