JPS55115877A - Novel amidine compound and its preparation - Google Patents
Novel amidine compound and its preparationInfo
- Publication number
- JPS55115877A JPS55115877A JP2396879A JP2396879A JPS55115877A JP S55115877 A JPS55115877 A JP S55115877A JP 2396879 A JP2396879 A JP 2396879A JP 2396879 A JP2396879 A JP 2396879A JP S55115877 A JPS55115877 A JP S55115877A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- compound shown
- preparation
- amidine compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An amidine compound shown by the formula I (X is N or methine; Y os O or S; R1 is H, alkyl, aminoalkyl or cycloalkylaminoalkyl which may be bonded through O in its chain; R2 is H or alkyl; m and n are 1W3; R3 is cyano, acyl, carbamoyl, trihalogenomethylcarbonyl; R4 is H, alkyl, alkenyl, etc.; R3 and R4 together with N form 5 or 6 membered heterocyclic ring) and its acid addition salt.
EXAMPLE: N-cyano-3-[ ( 5-dimethylaminomethylfuran-2-yl )methylthio ] propionamidine.
USE: An inhibitor of the secretion of acid in the stomach. Not depending upon an anticholinergic action.
PROCESS: For example, a compound shown by the formula III is reacted with an amine shown by the formula H2N-R4 to give a compound shown by the formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2396879A JPS55115877A (en) | 1979-02-28 | 1979-02-28 | Novel amidine compound and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2396879A JPS55115877A (en) | 1979-02-28 | 1979-02-28 | Novel amidine compound and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55115877A true JPS55115877A (en) | 1980-09-06 |
Family
ID=12125342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2396879A Pending JPS55115877A (en) | 1979-02-28 | 1979-02-28 | Novel amidine compound and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55115877A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0087274A2 (en) * | 1982-02-20 | 1983-08-31 | Smith Kline & French Laboratories Limited | Pyrimidone derivatives |
US4694008A (en) * | 1984-08-23 | 1987-09-15 | Smith Kline & French Laboratories Limited | Chemical compounds |
US4748165A (en) * | 1981-05-18 | 1988-05-31 | Imperial Chemical Industries Plc | Amidine derivatives |
JP2008162063A (en) * | 2006-12-27 | 2008-07-17 | King Jim Co Ltd | Binder and filing implement |
WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
-
1979
- 1979-02-28 JP JP2396879A patent/JPS55115877A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4748165A (en) * | 1981-05-18 | 1988-05-31 | Imperial Chemical Industries Plc | Amidine derivatives |
EP0087274A2 (en) * | 1982-02-20 | 1983-08-31 | Smith Kline & French Laboratories Limited | Pyrimidone derivatives |
US4808589A (en) * | 1982-02-20 | 1989-02-28 | Smith Kline & French Laboratories Limited | Pyrimidone derivatives |
US4694008A (en) * | 1984-08-23 | 1987-09-15 | Smith Kline & French Laboratories Limited | Chemical compounds |
JP2008162063A (en) * | 2006-12-27 | 2008-07-17 | King Jim Co Ltd | Binder and filing implement |
WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
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