IE830686L - 1,2,5-thiadiazoles - Google Patents
1,2,5-thiadiazolesInfo
- Publication number
- IE830686L IE830686L IE830686A IE68683A IE830686L IE 830686 L IE830686 L IE 830686L IE 830686 A IE830686 A IE 830686A IE 68683 A IE68683 A IE 68683A IE 830686 L IE830686 L IE 830686L
- Authority
- IE
- Ireland
- Prior art keywords
- thienyl
- formula
- image
- thiadiazoles
- gb2149406a
- Prior art date
Links
- 150000004868 1,2,5-thiadiazoles Chemical class 0.000 title 1
- -1 pyrrolidino - methylphenyl Chemical group 0.000 abstract 3
- 229940122957 Histamine H2 receptor antagonist Drugs 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- RDJGIQPSSNMJPF-UHFFFAOYSA-N ethanediimidamide Chemical class NC(=N)C(N)=N RDJGIQPSSNMJPF-UHFFFAOYSA-N 0.000 abstract 1
- 239000003485 histamine H2 receptor antagonist Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Substituted ethanediimidamides of the formula <IMAGE> wherein m is 0-2, n is 2-5, Z is O, S or methylene, R<1> is H or alkyl and A is exemplified as piperidino - or pyrrolidino - methylphenyl, dimethylaminomethyl-furyl or thienyl, or piperidinomethyl- thienyl or - pyridyl are used as intermediates to prepare histamine H2-receptor antagonists of the formula <IMAGE> as disclosed in parent specification No. 2117769.
[GB2149406A]
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE705/88A IE55560B1 (en) | 1982-03-29 | 1983-03-28 | Substituted diamino thiadiazole intermediates |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36320782A | 1982-03-29 | 1982-03-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE830686L true IE830686L (en) | 1983-09-29 |
| IE55596B1 IE55596B1 (en) | 1990-11-21 |
Family
ID=23429274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE686/83A IE55596B1 (en) | 1982-03-29 | 1983-03-28 | Substituted diamino thiadiazoles |
Country Status (30)
| Country | Link |
|---|---|
| JP (2) | JPS58180477A (en) |
| KR (1) | KR880002209B1 (en) |
| AT (1) | AT386599B (en) |
| AU (2) | AU557577B2 (en) |
| BE (1) | BE896291A (en) |
| CH (2) | CH655111A5 (en) |
| CS (2) | CS250229B2 (en) |
| DD (2) | DD210909A5 (en) |
| DE (1) | DE3311281A1 (en) |
| DK (2) | DK166677B1 (en) |
| ES (3) | ES520982A0 (en) |
| FR (2) | FR2542741B1 (en) |
| GB (2) | GB2117769B (en) |
| GR (1) | GR78524B (en) |
| HU (2) | HU188742B (en) |
| IE (1) | IE55596B1 (en) |
| IL (1) | IL68259A0 (en) |
| IT (1) | IT1164633B (en) |
| LU (1) | LU84716A1 (en) |
| MY (1) | MY8700942A (en) |
| NL (1) | NL8301063A (en) |
| NO (1) | NO163055C (en) |
| NZ (1) | NZ203726A (en) |
| OA (1) | OA07356A (en) |
| PT (1) | PT76459B (en) |
| SE (2) | SE461040B (en) |
| SU (2) | SU1419518A3 (en) |
| YU (1) | YU44849B (en) |
| ZA (1) | ZA832154B (en) |
| ZW (1) | ZW7683A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2222083A (en) * | 1982-12-14 | 1984-06-21 | Smith Kline & French Laboratories Limited | Pyridine derivatives |
| US4593039A (en) * | 1984-04-02 | 1986-06-03 | Merck & Co., Inc. | 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols |
| US4644006A (en) * | 1984-06-22 | 1987-02-17 | Bristol-Myers Company | Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity |
| JPH0622828B2 (en) * | 1986-06-30 | 1994-03-30 | フアナツク株式会社 | Direct pressure type mold clamping mechanism |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3018289A (en) * | 1960-02-10 | 1962-01-23 | Wyandotte Chemicals Corp | Process for preparing oxamidines |
| GB1595291A (en) * | 1976-09-21 | 1981-08-12 | Smith Kline French Lab | Pyrimidone and thiopyrimidone derivatives |
| FI76795C (en) * | 1979-09-04 | 1988-12-12 | Bristol Myers Co | Process for the preparation of novel, therapeutically useful 3,4-disubstituted 1,2,5-thiadiazole-1-oxides and -1,1-dioxides and novel intermediates |
| EP0040696B1 (en) * | 1980-04-30 | 1986-08-27 | Merck & Co. Inc. | Aminothiadiazoles as gastric secretion inhibitors |
| AU2222083A (en) * | 1982-12-14 | 1984-06-21 | Smith Kline & French Laboratories Limited | Pyridine derivatives |
-
1983
- 1983-03-25 ZA ZA832154A patent/ZA832154B/en unknown
- 1983-03-25 NL NL8301063A patent/NL8301063A/en not_active Application Discontinuation
- 1983-03-25 ZW ZW76/83A patent/ZW7683A1/en unknown
- 1983-03-25 FR FR838304934A patent/FR2542741B1/en not_active Expired
- 1983-03-25 ES ES520982A patent/ES520982A0/en active Granted
- 1983-03-28 GB GB08308518A patent/GB2117769B/en not_active Expired
- 1983-03-28 SE SE8301725A patent/SE461040B/en not_active IP Right Cessation
- 1983-03-28 AU AU12907/83A patent/AU557577B2/en not_active Ceased
- 1983-03-28 BE BE0/210417A patent/BE896291A/en not_active IP Right Cessation
- 1983-03-28 NZ NZ203726A patent/NZ203726A/en unknown
- 1983-03-28 HU HU831040A patent/HU188742B/en not_active IP Right Cessation
- 1983-03-28 IT IT48005/83A patent/IT1164633B/en active
- 1983-03-28 IL IL68259A patent/IL68259A0/en not_active IP Right Cessation
- 1983-03-28 GR GR70903A patent/GR78524B/el unknown
- 1983-03-28 DE DE19833311281 patent/DE3311281A1/en not_active Withdrawn
- 1983-03-28 DK DK141383A patent/DK166677B1/en not_active IP Right Cessation
- 1983-03-28 LU LU84716A patent/LU84716A1/en unknown
- 1983-03-28 NO NO831100A patent/NO163055C/en unknown
- 1983-03-28 SU SU833568849A patent/SU1419518A3/en active
- 1983-03-28 PT PT76459A patent/PT76459B/en not_active IP Right Cessation
- 1983-03-28 IE IE686/83A patent/IE55596B1/en not_active IP Right Cessation
- 1983-03-28 HU HU854071A patent/HU196386B/en not_active IP Right Cessation
- 1983-03-29 KR KR1019830001283A patent/KR880002209B1/en not_active Expired
- 1983-03-29 YU YU744/83A patent/YU44849B/en unknown
- 1983-03-29 CH CH1749/83A patent/CH655111A5/en not_active IP Right Cessation
- 1983-03-29 AT AT0111083A patent/AT386599B/en not_active IP Right Cessation
- 1983-03-29 DD DD83249300A patent/DD210909A5/en not_active IP Right Cessation
- 1983-03-29 DD DD83260707A patent/DD219768A5/en not_active IP Right Cessation
- 1983-03-29 OA OA57955A patent/OA07356A/en unknown
- 1983-03-29 JP JP58051740A patent/JPS58180477A/en active Granted
- 1983-03-29 CH CH575/86A patent/CH660880A5/en not_active IP Right Cessation
- 1983-03-29 CS CS832191A patent/CS250229B2/en unknown
- 1983-03-29 CS CS841958A patent/CS250240B2/en unknown
- 1983-11-30 ES ES527685A patent/ES527685A0/en active Granted
- 1983-11-30 ES ES527686A patent/ES527686A0/en active Granted
-
1984
- 1984-06-08 SU SU843750493A patent/SU1355123A3/en active
- 1984-12-31 GB GB08432809A patent/GB2149406B/en not_active Expired
-
1986
- 1986-09-30 AU AU63272/86A patent/AU586037B2/en not_active Ceased
-
1987
- 1987-05-22 FR FR878707197A patent/FR2597867B1/en not_active Expired
- 1987-11-25 SE SE8704689A patent/SE464302B/en not_active IP Right Cessation
- 1987-12-30 MY MY942/87A patent/MY8700942A/en unknown
-
1992
- 1992-06-18 DK DK92811A patent/DK81192D0/en not_active Application Discontinuation
-
1993
- 1993-04-16 JP JP5124585A patent/JPH06135925A/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |