JP2008500277A5 - - Google Patents
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- Publication number
- JP2008500277A5 JP2008500277A5 JP2006552536A JP2006552536A JP2008500277A5 JP 2008500277 A5 JP2008500277 A5 JP 2008500277A5 JP 2006552536 A JP2006552536 A JP 2006552536A JP 2006552536 A JP2006552536 A JP 2006552536A JP 2008500277 A5 JP2008500277 A5 JP 2008500277A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- days
- human immunoglobulin
- administration
- formulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108060003951 Immunoglobulin Proteins 0.000 claims 10
- 102000018358 immunoglobulin Human genes 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 5
- 210000002966 serum Anatomy 0.000 claims 5
- 102000018651 Epithelial Cell Adhesion Molecule Human genes 0.000 claims 2
- 108010066687 Epithelial Cell Adhesion Molecule Proteins 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 208000006990 cholangiocarcinoma Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 230000001613 neoplastic effect Effects 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 206010004593 Bile duct cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 206010014733 Endometrial cancer Diseases 0.000 claims 1
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 208000022072 Gallbladder Neoplasms Diseases 0.000 claims 1
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims 1
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims 1
- 102000013463 Immunoglobulin Light Chains Human genes 0.000 claims 1
- 108010065825 Immunoglobulin Light Chains Proteins 0.000 claims 1
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 206010038389 Renal cancer Diseases 0.000 claims 1
- 208000004337 Salivary Gland Neoplasms Diseases 0.000 claims 1
- 206010061934 Salivary gland cancer Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 208000026900 bile duct neoplasm Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 201000010175 gallbladder cancer Diseases 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 201000010982 kidney cancer Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 201000002314 small intestine cancer Diseases 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 201000002510 thyroid cancer Diseases 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/778,915 US20050180979A1 (en) | 2004-02-13 | 2004-02-13 | Anti-EpCAM immunoglobulins |
| US10/778,915 | 2004-02-13 | ||
| PCT/EP2005/001307 WO2005080428A2 (en) | 2004-02-13 | 2005-02-09 | Anti-epcam immunoglobulins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008500277A JP2008500277A (ja) | 2008-01-10 |
| JP2008500277A5 true JP2008500277A5 (enExample) | 2008-04-03 |
| JP5220315B2 JP5220315B2 (ja) | 2013-06-26 |
Family
ID=34838270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552536A Expired - Fee Related JP5220315B2 (ja) | 2004-02-13 | 2005-02-09 | 抗ＥｐＣＡＭ免疫グロブリン |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20050180979A1 (enExample) |
| EP (2) | EP1713830B1 (enExample) |
| JP (1) | JP5220315B2 (enExample) |
| KR (1) | KR101236224B1 (enExample) |
| CN (1) | CN1976951B (enExample) |
| AT (1) | ATE437186T1 (enExample) |
| AU (1) | AU2005215874B2 (enExample) |
| BR (1) | BRPI0507660A (enExample) |
| CA (1) | CA2555694C (enExample) |
| DE (1) | DE602005015544D1 (enExample) |
| DK (1) | DK1713830T3 (enExample) |
| EA (1) | EA011951B1 (enExample) |
| ES (1) | ES2328159T3 (enExample) |
| IL (1) | IL177069A (enExample) |
| MX (1) | MXPA06008942A (enExample) |
| NO (1) | NO339364B1 (enExample) |
| NZ (1) | NZ549125A (enExample) |
| PL (1) | PL1713830T3 (enExample) |
| PT (1) | PT1713830E (enExample) |
| SI (1) | SI1713830T1 (enExample) |
| UA (1) | UA87128C2 (enExample) |
| WO (1) | WO2005080428A2 (enExample) |
| ZA (1) | ZA200606083B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070122406A1 (en) | 2005-07-08 | 2007-05-31 | Xencor, Inc. | Optimized proteins that target Ep-CAM |
| EP2474822A1 (en) | 2003-01-24 | 2012-07-11 | University of Utah | Methods of predicting mortality risk by determining telomere length |
| AU2007213920B2 (en) * | 2006-02-09 | 2013-08-29 | Amgen Research (Munich) Gmbh | Treatment of metastatic breast cancer |
| DK2041181T3 (da) * | 2006-06-08 | 2011-08-29 | Helmholtz Zentrum Muenchen | Specifikke proteaseinhibitorer og deres anvendelse i cancerterapi |
| EP1865001A1 (en) * | 2006-06-08 | 2007-12-12 | Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh | Specific protease inhibitors and their use in cancer therapy |
| EP2142570B1 (en) * | 2007-04-04 | 2011-06-15 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Anti-epcam antibody and uses thereof |
| CA2748265C (en) | 2008-12-22 | 2018-04-03 | University Of Utah Research Foundation | Monochrome multiplex quantitative pcr |
| EP2480687B1 (en) * | 2009-09-21 | 2015-01-28 | Paul Walfish | Methods and compositions for the diagnosis and treatment of thyroid cancer |
| EP2819695B1 (en) * | 2012-03-02 | 2018-06-27 | Academia Sinica | ANTI-EPITHELIAL CELL ADHESION MOLECULE (EpCAM) ANTIBODIES AND METHODS OF USE THEREOF |
| CN103387988B (zh) * | 2012-09-24 | 2016-01-06 | 厦门大学 | 上皮细胞粘附分子的核酸适体EpCAM Ccut及其制备方法 |
| EP2999800B1 (en) | 2013-05-22 | 2019-09-25 | Telomere Diagnostics Inc. | Measures of short telomere abundance |
| CN103275226B (zh) * | 2013-06-09 | 2017-08-29 | 中国科学技术大学 | 特异性抗人上皮细胞粘附分子（EpCAM）的单克隆抗体的制备、鉴定及应用 |
| ES2728668T3 (es) * | 2014-01-08 | 2019-10-28 | Univ Leland Stanford Junior | Terapia dirigida para el cáncer de pulmón de células pequeñas |
| CA2971169A1 (en) | 2014-12-30 | 2016-07-07 | Telomere Diagnostics, Inc. | Multiplex quantitative pcr |
| AU2016358296B2 (en) * | 2015-11-19 | 2020-05-21 | Revitope Limited | Functional antibody fragment complementation for a two-components system for redirected killing of unwanted cells |
| KR20190038567A (ko) | 2016-07-26 | 2019-04-08 | 테사 테라퓨틱스 피티이. 엘티디. | 키메라 항원 수용체 |
| WO2020018964A1 (en) | 2018-07-20 | 2020-01-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for controlled expression of antigen-specific receptors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5853697A (en) * | 1995-10-25 | 1998-12-29 | The United States Of America, As Represented By The Department Of Health & Human Services | Methods of treating established colitis using antibodies against IL-12 |
| BRPI9809391B8 (pt) * | 1997-04-14 | 2021-05-25 | Amgen Res Munich Gmbh | processo para a produção de um receptor de antígeno anti-humano, anticorpo humano e composição farmacêutica |
| US6855544B1 (en) * | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
| US7605238B2 (en) * | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| DK1383785T3 (da) * | 2001-05-03 | 2011-05-23 | Merck Patent Gmbh | Rekombinant tumorspecifikt antistof og anvendelse deraf |
| US20030175268A1 (en) * | 2002-01-11 | 2003-09-18 | Saint-Remy Jean-Marie R. | Method and pharmaceutical composition for preventing and/or treating systemic inflammatory response syndrome |
| PL375064A1 (en) * | 2002-05-20 | 2005-11-14 | Abgenix, Inc. | Treatment of renal carcinoma using antibodies against the egfr |
-
2004
- 2004-02-13 US US10/778,915 patent/US20050180979A1/en not_active Abandoned
-
2005
- 2005-02-09 EA EA200601386A patent/EA011951B1/ru not_active IP Right Cessation
- 2005-02-09 BR BRPI0507660-9A patent/BRPI0507660A/pt not_active Application Discontinuation
- 2005-02-09 AT AT05707293T patent/ATE437186T1/de active
- 2005-02-09 UA UAA200608985A patent/UA87128C2/ru unknown
- 2005-02-09 EP EP05707293A patent/EP1713830B1/en not_active Expired - Lifetime
- 2005-02-09 EP EP09165284A patent/EP2107071A3/en not_active Withdrawn
- 2005-02-09 CN CN2005800099764A patent/CN1976951B/zh not_active Expired - Fee Related
- 2005-02-09 NZ NZ549125A patent/NZ549125A/en not_active IP Right Cessation
- 2005-02-09 DK DK05707293T patent/DK1713830T3/da active
- 2005-02-09 SI SI200530759T patent/SI1713830T1/sl unknown
- 2005-02-09 PT PT05707293T patent/PT1713830E/pt unknown
- 2005-02-09 CA CA2555694A patent/CA2555694C/en not_active Expired - Fee Related
- 2005-02-09 KR KR1020067016339A patent/KR101236224B1/ko not_active Expired - Fee Related
- 2005-02-09 MX MXPA06008942A patent/MXPA06008942A/es active IP Right Grant
- 2005-02-09 DE DE602005015544T patent/DE602005015544D1/de not_active Expired - Lifetime
- 2005-02-09 JP JP2006552536A patent/JP5220315B2/ja not_active Expired - Fee Related
- 2005-02-09 WO PCT/EP2005/001307 patent/WO2005080428A2/en not_active Ceased
- 2005-02-09 AU AU2005215874A patent/AU2005215874B2/en not_active Ceased
- 2005-02-09 US US10/589,450 patent/US20070274982A1/en not_active Abandoned
- 2005-02-09 PL PL05707293T patent/PL1713830T3/pl unknown
- 2005-02-09 ES ES05707293T patent/ES2328159T3/es not_active Expired - Lifetime
-
2006
- 2006-07-21 ZA ZA200606083A patent/ZA200606083B/en unknown
- 2006-07-25 IL IL177069A patent/IL177069A/en not_active IP Right Cessation
- 2006-09-13 NO NO20064136A patent/NO339364B1/no not_active IP Right Cessation
-
2012
- 2012-06-01 US US13/486,749 patent/US20120294873A1/en not_active Abandoned