CA2555694C - Anti-epcam immunoglobulins - Google Patents

Anti-epcam immunoglobulins Download PDF

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Publication number
CA2555694C
CA2555694C CA2555694A CA2555694A CA2555694C CA 2555694 C CA2555694 C CA 2555694C CA 2555694 A CA2555694 A CA 2555694A CA 2555694 A CA2555694 A CA 2555694A CA 2555694 C CA2555694 C CA 2555694C
Authority
CA
Canada
Prior art keywords
cancer
epcam
immunoglobulin
serum
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2555694A
Other languages
English (en)
French (fr)
Other versions
CA2555694A1 (en
Inventor
Malte Peters
Mathias Locher
Nadja Prang
Cornelia Quadt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Research Munich GmbH
Original Assignee
Amgen Research Munich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Research Munich GmbH filed Critical Amgen Research Munich GmbH
Publication of CA2555694A1 publication Critical patent/CA2555694A1/en
Application granted granted Critical
Publication of CA2555694C publication Critical patent/CA2555694C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA2555694A 2004-02-13 2005-02-09 Anti-epcam immunoglobulins Expired - Fee Related CA2555694C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/778,915 US20050180979A1 (en) 2004-02-13 2004-02-13 Anti-EpCAM immunoglobulins
US10/778,915 2004-02-13
PCT/EP2005/001307 WO2005080428A2 (en) 2004-02-13 2005-02-09 Anti-epcam immunoglobulins

Publications (2)

Publication Number Publication Date
CA2555694A1 CA2555694A1 (en) 2005-09-01
CA2555694C true CA2555694C (en) 2013-04-16

Family

ID=34838270

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2555694A Expired - Fee Related CA2555694C (en) 2004-02-13 2005-02-09 Anti-epcam immunoglobulins

Country Status (23)

Country Link
US (3) US20050180979A1 (enExample)
EP (2) EP1713830B1 (enExample)
JP (1) JP5220315B2 (enExample)
KR (1) KR101236224B1 (enExample)
CN (1) CN1976951B (enExample)
AT (1) ATE437186T1 (enExample)
AU (1) AU2005215874B2 (enExample)
BR (1) BRPI0507660A (enExample)
CA (1) CA2555694C (enExample)
DE (1) DE602005015544D1 (enExample)
DK (1) DK1713830T3 (enExample)
EA (1) EA011951B1 (enExample)
ES (1) ES2328159T3 (enExample)
IL (1) IL177069A (enExample)
MX (1) MXPA06008942A (enExample)
NO (1) NO339364B1 (enExample)
NZ (1) NZ549125A (enExample)
PL (1) PL1713830T3 (enExample)
PT (1) PT1713830E (enExample)
SI (1) SI1713830T1 (enExample)
UA (1) UA87128C2 (enExample)
WO (1) WO2005080428A2 (enExample)
ZA (1) ZA200606083B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070122406A1 (en) 2005-07-08 2007-05-31 Xencor, Inc. Optimized proteins that target Ep-CAM
EP2474822A1 (en) 2003-01-24 2012-07-11 University of Utah Methods of predicting mortality risk by determining telomere length
AU2007213920B2 (en) * 2006-02-09 2013-08-29 Amgen Research (Munich) Gmbh Treatment of metastatic breast cancer
DK2041181T3 (da) * 2006-06-08 2011-08-29 Helmholtz Zentrum Muenchen Specifikke proteaseinhibitorer og deres anvendelse i cancerterapi
EP1865001A1 (en) * 2006-06-08 2007-12-12 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Specific protease inhibitors and their use in cancer therapy
EP2142570B1 (en) * 2007-04-04 2011-06-15 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Anti-epcam antibody and uses thereof
CA2748265C (en) 2008-12-22 2018-04-03 University Of Utah Research Foundation Monochrome multiplex quantitative pcr
EP2480687B1 (en) * 2009-09-21 2015-01-28 Paul Walfish Methods and compositions for the diagnosis and treatment of thyroid cancer
EP2819695B1 (en) * 2012-03-02 2018-06-27 Academia Sinica ANTI-EPITHELIAL CELL ADHESION MOLECULE (EpCAM) ANTIBODIES AND METHODS OF USE THEREOF
CN103387988B (zh) * 2012-09-24 2016-01-06 厦门大学 上皮细胞粘附分子的核酸适体EpCAM Ccut及其制备方法
EP2999800B1 (en) 2013-05-22 2019-09-25 Telomere Diagnostics Inc. Measures of short telomere abundance
CN103275226B (zh) * 2013-06-09 2017-08-29 中国科学技术大学 特异性抗人上皮细胞粘附分子(EpCAM)的单克隆抗体的制备、鉴定及应用
ES2728668T3 (es) * 2014-01-08 2019-10-28 Univ Leland Stanford Junior Terapia dirigida para el cáncer de pulmón de células pequeñas
CA2971169A1 (en) 2014-12-30 2016-07-07 Telomere Diagnostics, Inc. Multiplex quantitative pcr
AU2016358296B2 (en) * 2015-11-19 2020-05-21 Revitope Limited Functional antibody fragment complementation for a two-components system for redirected killing of unwanted cells
KR20190038567A (ko) 2016-07-26 2019-04-08 테사 테라퓨틱스 피티이. 엘티디. 키메라 항원 수용체
WO2020018964A1 (en) 2018-07-20 2020-01-23 Fred Hutchinson Cancer Research Center Compositions and methods for controlled expression of antigen-specific receptors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853697A (en) * 1995-10-25 1998-12-29 The United States Of America, As Represented By The Department Of Health & Human Services Methods of treating established colitis using antibodies against IL-12
BRPI9809391B8 (pt) * 1997-04-14 2021-05-25 Amgen Res Munich Gmbh processo para a produção de um receptor de antígeno anti-humano, anticorpo humano e composição farmacêutica
US6855544B1 (en) * 1999-04-15 2005-02-15 Crucell Holland B.V. Recombinant protein production in a human cell
US7605238B2 (en) * 1999-08-24 2009-10-20 Medarex, Inc. Human CTLA-4 antibodies and their uses
DK1383785T3 (da) * 2001-05-03 2011-05-23 Merck Patent Gmbh Rekombinant tumorspecifikt antistof og anvendelse deraf
US20030175268A1 (en) * 2002-01-11 2003-09-18 Saint-Remy Jean-Marie R. Method and pharmaceutical composition for preventing and/or treating systemic inflammatory response syndrome
PL375064A1 (en) * 2002-05-20 2005-11-14 Abgenix, Inc. Treatment of renal carcinoma using antibodies against the egfr

Also Published As

Publication number Publication date
WO2005080428A2 (en) 2005-09-01
PL1713830T3 (pl) 2010-01-29
JP2008500277A (ja) 2008-01-10
JP5220315B2 (ja) 2013-06-26
DK1713830T3 (da) 2009-10-12
AU2005215874B2 (en) 2011-01-27
PT1713830E (pt) 2009-10-19
CN1976951B (zh) 2012-03-14
US20120294873A1 (en) 2012-11-22
ATE437186T1 (de) 2009-08-15
HK1096103A1 (en) 2007-05-25
ZA200606083B (en) 2007-10-31
WO2005080428A3 (en) 2005-11-10
SI1713830T1 (sl) 2009-10-31
EA200601386A1 (ru) 2007-06-29
NO20064136L (no) 2006-11-07
MXPA06008942A (es) 2007-01-26
AU2005215874A1 (en) 2005-09-01
US20050180979A1 (en) 2005-08-18
KR20070009988A (ko) 2007-01-19
IL177069A0 (en) 2006-12-10
US20070274982A1 (en) 2007-11-29
CA2555694A1 (en) 2005-09-01
KR101236224B1 (ko) 2013-02-22
BRPI0507660A (pt) 2007-07-17
UA87128C2 (ru) 2009-06-25
EA011951B1 (ru) 2009-06-30
NZ549125A (en) 2008-09-26
NO339364B1 (no) 2016-12-05
EP2107071A2 (en) 2009-10-07
EP1713830A2 (en) 2006-10-25
EP1713830B1 (en) 2009-07-22
EP2107071A3 (en) 2009-12-30
DE602005015544D1 (de) 2009-09-03
CN1976951A (zh) 2007-06-06
ES2328159T3 (es) 2009-11-10
IL177069A (en) 2010-11-30

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Effective date: 20200210